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Purified anti-mouse CD16/32 Antibody

Pricing & Availability
Clone
93 (See other available formats)
Regulatory Status
RUO
Other Names
Fcγ R III/II, Ly-17
Isotype
Rat IgG2a, λ
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Product Citations
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93_purified_051906
C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
  • 93_purified_051906
    C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
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101301 50 µg 29€
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101302 500 µg 92€
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Description

CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Sorted pre-B cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The CD16/32 antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IP, Block - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone 93 can be used for blocking of CD16/CD32 interactions with the Fc domain of immunoglobulins, but is not the same clone as 2.4G2.

The 93 mAb is specific to the common epitope of CD16/CD32. Additional reported applications (for the relevant formats) include: immunoprecipitation1 and blocking of Fc-mediated reactions in functional studies2,4,23. It is useful for blocking non-specific binding of immunoglobulin to Fc receptors. For blocking of Fc receptors in flow cytometric analysis, pre-incubate the cells with purified anti-CD16/CD32 antibody (=1.0 µg per 106 cells in 100 µL volume) for 5-10 minutes on ice prior to immunostaining. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 101330) (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered).

Application References

(PubMed link indicates BioLegend citation)
  1. Personal communication (IP)
  2. Oliver AM, et al. 1999. Hybridoma 18:113. (Block)
  3. Brummel R and Lenert P. 2005. J. Immunol. 174:2429.
  4. Terrazas LI, et al. 2005. Int. J. Parasitol. 35:1349. (Block)
  5. Clements JL, et al. 2006. J. Immunol. 177:905.
  6. Mohamed W, et al. 2010. Infect Immun. 78:3306. PubMed
  7. Ouchi T, et al. 2011. J. Exp Med. 208:2607. PubMed
  8. Kmieciak M, et al. 2011. J. Vis. Exp. 47:2381. PubMed
  9. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  10. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  11. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  12. Koon HW, et al. 2013. J. Vis. Exp. 68:4208. PubMed
  13. Hegde VL, et al. 2013. J Biol Chem. 288:36810. PubMed
  14. Huang J, et al. 2013. J. Immunol Methods. 387:254. PubMed
  15. Dutow P, et al. 2014. J Infect Dis. PubMed
  16. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  17. Huang HN, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  18. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  19. Richardson ML, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  20. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  21. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  22. Everad A, et al. 2014. Nat Commun. 5:5648. PubMed
  23. Cenci E, et al. 2006. J. Leuko. Biol. 79(1):40-5. (Block)
Product Citations
  1. Rajagopalan A, et al. 2021. Cell Rep Methods. 1:. PubMed
  2. Guo H, et al. 2020. Curr Protoc Immunol. 131:e107. PubMed
  3. Van Braeckel-Budimir N, et al. 2021. J Immunother Cancer. 9:. PubMed
  4. Wang Z, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  5. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  6. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  7. Jebbawi F, et al. 2021. Parasite Immunol. 43:e12834. PubMed
  8. Thomas R, et al. 2021. Immunology. 163:478. PubMed
  9. Herz J, et al. 2021. Neuron. 109:3609. PubMed
  10. Li H, et al. 2022. Cancer Cell. 40:36. PubMed
  11. Glynn RA, et al. 2022. J Immunol. 208:371. PubMed
  12. Kozuki S, et al. 2022. Genes Cells. 27:192. PubMed
  13. Bettke JA, et al. 2022. Infect Immun. 90:e0007022. PubMed
  14. Guttman O, et al. 2022. J Cell Biol. 221: . PubMed
  15. Miyao T, et al. 2022. Elife. 11: . PubMed
  16. Yin K, et al. 2022. Genes Dev. 36:533. PubMed
  17. Malhi H, et al. 2022. Cell Rep Med. 3:100658. PubMed
  18. Zhang Y, et al. 2022. Vaccines (Basel). 10: . PubMed
  19. Sugimoto S, et al. 2022. Nat Metab. 4:775. PubMed
  20. Hong Y, et al. 2022. J Leukoc Biol. 112:425. PubMed
  21. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  22. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  23. Akalu YT, et al. 2022. Elife. 11: . PubMed
  24. Zhang X, et al. 2022. EBioMedicine. 84:104275. PubMed
  25. Bottermann K, et al. 2022. Basic Res Cardiol. 117:48. PubMed
  26. Hao J, et al. 2022. Cell Rep. 41:111804. PubMed
  27. McNamara NB, et al. 2023. Nature. 613:120. PubMed
  28. Miró L, et al. 2022. Cancers (Basel). 14: . PubMed
  29. Liu P, et al. 2023. Clin Immunol. 246:109212. PubMed
  30. Ullah I, et al. 2023. Cell Rep Med. 4:100893. PubMed
  31. Al-Saafeen BH, et al. 2023. Front Immunol. 13:1017780. PubMed
  32. Cousin N, et al. 2022. Cells. 12: . PubMed
  33. Peng Q, et al. 2023. EMBO Rep. 24:e56034. PubMed
  34. Tichet M, et al. 2023. Immunity. 56:162. PubMed
  35. Zhou H, et al. 2023. Front Immunol. 13:1059687. PubMed
  36. Mandour MF, et al. 2023. Front Med (Lausanne). 9:1057252. PubMed
  37. Kemna J, et al. 2023. Nat Immunol. 24:414. PubMed
  38. Novaj A, et al. 2023. Int J Mol Sci. 24: . PubMed
  39. Ishikawa T, et al. 2023. Bio Protoc. 13:e4588. PubMed
  40. Liu X, et al. 2022. Pain. 163:508. PubMed
  41. Zhang M, et al. 2022. Mol Imaging Biol. 24:280. PubMed
  42. Zhang W, et al. 2022. Dev Cell. 57:329. PubMed
  43. Kodali S, et al. 2022. J Immunol. 208:1085. PubMed
  44. Chen K, et al. 2022. Adv Sci (Weinh). 9:e2104106. PubMed
  45. Zhang H, et al. 2022. Nat Cancer. 3:808. PubMed
  46. Fang Y, et al. 2022. Sci Immunol. 7:eabp9962. PubMed
  47. Koch MS, et al. 2022. Mol Ther Oncolytics. 26:275. PubMed
  48. Harapas CR, et al. 2022. Sci Immunol. 7:eabi4611. PubMed
  49. Ding P, et al. 2022. Elife. 11:. PubMed
  50. Deák P, et al. 2022. Cell Rep. 41:111563. PubMed
  51. Zhong J, et al. 2022. J Adv Res. 41:145. PubMed
  52. Melo-Silva CR, et al. 2022. Cell Rep. 41:111676. PubMed
  53. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  54. Wu Q, et al. 2023. Front Immunol. 13:1081719. PubMed
  55. Li L, et al. 2023. iScience. 26:106095. PubMed
  56. Torrente D, et al. 2023. J Neuroinflammation. 20:56. PubMed
  57. Bai X, et al. 2023. Nat Commun. 14:1247. PubMed
  58. Rocca Y, et al. 2023. Methods Mol Biol. 2618:187. PubMed
  59. Dang YZ, et al. 2023. Neoplasma. 70:123. PubMed
  60. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  61. Kudo T, et al. 2023. iScience. 26:106342. PubMed
  62. Liu KY, et al. 2023. Environ Health Perspect. 131:37014. PubMed
  63. Zhang YN, et al. 2023. Nat Commun. 14:1985. PubMed
  64. Iguchi A, et al. 2023. iScience. 26:106375. PubMed
  65. Feng Y, et al. 2023. J Transl Med. 21:290. PubMed
  66. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  67. Liu JC, et al. 2023. Int J Mol Sci. 24:. PubMed
  68. Petenkova A, et al. 2023. Nat Commun. 14:2761. PubMed
  69. Xu J, et al. 2023. Discov Oncol. 14:68. PubMed
  70. An R, et al. 2022. Cell Insight. 1:100047. PubMed
  71. Wang K, et al. 2023. Nat Commun. 14:2950. PubMed
  72. Amirova KM, et al. 2023. Int J Mol Sci. 24:. PubMed
  73. Li M, et al. 2023. BMC Cancer. 23:497. PubMed
  74. Mawambo G, et al. 2023. J Neuroinflammation. 20:145. PubMed
  75. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  76. Cerrato G, et al. 2021. Cell Death Differ. 28:1733. PubMed
  77. Da Mesquita S, et al. 2021. Nature. 593:255. PubMed
  78. Liu C, et al. 2022. Nat Nanotechnol. 17:531. PubMed
  79. Sade-Feldman M,et al. 2017. Nat Commun.. 10.1038/s41467-017-01062-w. PubMed
  80. Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed
  81. Gan T, et al. 2019. Front Microbiol. 9:3174. PubMed
  82. Furuhashi K, et al. 2017. Immunology. 151:227. PubMed
  83. Fomin ME, et al. 2017. Cell Med. 0.45625. PubMed
  84. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  85. Filippini D, et al. 2019. Sci Rep. 9:12286. PubMed
  86. Flamar AL, et al. 2020. Immunity. 52(4):606-619.e6.. PubMed
  87. Lee J, et al. 2015. Hum Reprod. 10.1093/humrep/dev222. PubMed
  88. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  89. Chida J, et al. 2020. PLoS Pathog. 16:e1008823. PubMed
  90. Iyer S, et al. 2021. Cancer Discov. 0.725. PubMed
  91. Park E, et al. 2021. Journal of Neuroscience Research. . PubMed
  92. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  93. Kosti P, et al. 2021. Cell Reports Medicine. 2(4):100227. PubMed
  94. Barkaway A, et al. 2021. Immunity. . PubMed
  95. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  96. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  97. Foster A, et al. 2021. EBioMedicine. 71:103571. PubMed
  98. Kiepura A, et al. 2021. Int J Mol Sci. 22:. PubMed
  99. Kitagawa S, et al. 2022. NPJ Vaccines. 7:115. PubMed
  100. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  101. Yu Y, et al. 2022. iScience. 25:105004. PubMed
  102. Huang Y, et al. 2021. Nat Immunol. 22:586. PubMed
  103. MacLean M, et al. 2022. Commun Biol. 5:177. PubMed
  104. Effern M, et al. 2022. STAR Protoc. 3:101038. PubMed
  105. Berry CT, et al. 2020. Cell Reports. 31(2):107474.. PubMed
  106. Rendeiro AF, et al. 2020. Nat Commun. 11:577. PubMed
  107. Biljes D, et al. 2017. EXCLI J. 0.86875. PubMed
  108. Zhang R, et al. 2019. Cell Rep. 28:2647. PubMed
  109. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  110. Zou B, et al. 2017. PLoS Pathogens. 13(6):e1006436. PubMed
  111. Rødahl I, et al. 2021. STAR Protoc. 2:100842. PubMed
  112. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
  113. Wong Fok Lung T, et al. 2020. Nat Microbiol. 141:5. PubMed
  114. Qian Y, et al. 2021. Cell Reports. 36(8):109602. PubMed
  115. Benitez AA, et al. 2020. Commun Biol. 0.371527778. PubMed
  116. Castoldi Â, et al. 2020. Nat Commun. 3.310416667. PubMed
  117. Mevel R, et al. 2020. eLife. 9:00. PubMed
  118. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  119. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  120. Khamissi FZ, et al. 2022. Sci Adv. 8:eabm5900. PubMed
  121. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  122. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  123. Feng J, et al. 2021. iScience. 24:103004. PubMed
  124. Wu L, et al. 2022. Front Immunol. 13:860761. PubMed
  125. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  126. Tan H,et al. 2017. Mucosal Immunol. . 10.1038/mi.2017.89. PubMed
  127. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  128. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  129. Minutti CM, et al. 2019. Immunity. 50:645. PubMed
  130. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  131. Takeda Y, et al. 2018. Innate Immun. 24:323. PubMed
  132. Goel S, et al. 2017. Nature. 548:471. PubMed
  133. Matsui S, et al. 2018. Am J Pathol. 188:2059. PubMed
  134. Bhatia D, et al. 2019. JCI Insight. 4:e132826. PubMed
  135. Noh JR, et al. 2018. Sci Rep. 8:15222. PubMed
  136. Flores M, et al. 2008. FASEB J. 3.459027778. PubMed
  137. Tong J, et al. 2011. J Immunol. 186:3686. PubMed
  138. Weng L, et al. 2016. Sci Rep. 6:38632. PubMed
  139. Browning D, et al. 2017. Gene Ther. 10.1038/gt.2016.88. PubMed
  140. Morris MG, et al. 2020. Comp Med. 70:336. PubMed
  141. Sano T, et al. 2021. Cell Reports. 36:109608. PubMed
  142. Martos-Rus C, et al. 2021. Sci Rep. 11:2974. PubMed
  143. Liu P, et al. 2021. Front Med (Lausanne). 8:625130. PubMed
  144. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  145. Diao L, et al. 2022. iScience. 25:105511. PubMed
  146. Zhang Y, et al. 2022. Cancers (Basel). 14:. PubMed
  147. Mirshahi F, et al. 2022. Cell Rep. 38:110454. PubMed
  148. Sun SJ, et al. 2022. Commun Biol. 5:867. PubMed
  149. Chen X, et al. 2021. Cell Death Differ. 28:1237. PubMed
  150. Roberto Raúl SG, et al. 2022. Breast Cancer (Auckl). 16:11782234211065154. PubMed
  151. Matthias J, et al. 2020. J Clin Invest. 130:4587. PubMed
  152. Menzel L, et al. 2021. Cell Rep. 37:109878. PubMed
  153. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  154. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  155. Hays C, et al. 2020. eLife. 8:e48772.. PubMed
  156. Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
  157. Gawden‐Bone CM et al. 2018. Immunity. 49(3):427-437 . PubMed
  158. Tyagi AM et al. 2018. Immunity. 49(6):1116-1131 . PubMed
  159. Oyarce C, et al. 2018. Front Immunol. 8:1794. PubMed
  160. Liang F, et al. 2021. Front Immunol. 12:658715. PubMed
  161. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  162. Clark AL, et al. 2021. Diabetes Obesity and Metabolism. :. PubMed
  163. Stahnke S, et al. 2021. Current Biology. 31(10):2051-2064.e8. PubMed
  164. Yang SB, et al. 2021. Cancers (Basel). 13:00. PubMed
  165. Elisabeth Schrumpf, Xiaojun Jiang 2017. Physiol Rep. 10.14814/phy2.13117. PubMed
  166. Koon H, et al. 2012. J Vis Exp. 68: 4208. PubMed
  167. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  168. Armaka M, et al. 2022. Genome Med. 14:78. PubMed
  169. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  170. Shen H, et al. 2022. Nat Commun. 13:6030. PubMed
  171. Nakagawa S et al. 2017. Cell host & microbe. 22(5):667-677 . PubMed
  172. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
  173. Fiala GJ, et al. 2019. J Immunol. 203:569. PubMed
  174. Dave K et al. 2017. eLife. 6 pii: e23382. PubMed
  175. Kitashima DY, et al. 2018. EBioMedicine. 27:293. PubMed
  176. Li Y, et al. 2018. J Immunol. 201:2910. PubMed
  177. Carlson P, et al. 2019. Nat Cell Biol. 21:238. PubMed
  178. Wu J, et al. 2020. Sci Adv. 6:eaba3458. PubMed
  179. Guan H, et al. 2012. PLoS One. 7:e35650. PubMed
  180. Hazama D, et al. 2020. Cell Chemical Biology. 27(9):1181-1191.e7. PubMed
  181. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  182. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  183. Okuniewska M, et al. 2021. Cell Reports. 36(2):109368. PubMed
  184. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  185. Webster HC, et al. 2020. J Immunol Methods. 112702:477. PubMed
  186. Godbersen-Palmer C, et al. 2020. J Immunol. 204:2973. PubMed
  187. Yang C, et al. 2020. J Control Release. 326:324. PubMed
  188. Liu D, et al. 2021. JCI Insight. 6:. PubMed
  189. Wang Y, et al. 2022. Front Immunol. 13:767630. PubMed
  190. Terrazas LI, et al. 2005. Int J Parasit. 35:1349. PubMed
  191. Bhattacherjee A, et al. 2019. Commun Biol. 2:450. PubMed
  192. Lieschke S, et al. 2019. Cells. 0.420833333. PubMed
  193. Sereni L, et al. 2018. J Allergy Clin Immunol. 142:1272. PubMed
  194. Fransen F, et al. 2017. Front Immunol. 1.295138889. PubMed
  195. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  196. Wlodarska M et al. 2017. Cell host & microbe. 22(1):25-37 . PubMed
  197. Ma J, et al. 2021. Aging (Albany NY). 13:7211. PubMed
  198. Yu M, et al. 2021. J Clin Invest. 131:. PubMed
  199. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  200. Haugh KA, et al. 2021. eLife. 0.416666666666667. PubMed
  201. Tal MC, et al. 2020. MBio. 11:00. PubMed
  202. Zhang X, et al. 2020. J Immunol. 205:1743. PubMed
  203. Kovacs L, et al. 2020. PLoS One. 15:e0240455. PubMed
  204. Vackova J, et al. 2020. Int J Mol Sci. 21:00. PubMed
  205. Mao W, et al. 2021. Int J Mol Sci. 22:. PubMed
  206. Dang Y, et al. 2022. Cancer Cell Int. 22:88. PubMed
  207. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  208. Cong M, et al. 2021. Methods Mol Biol. 2388:59. PubMed
  209. Menzel L, et al. 2022. STAR Protoc. 3:101267. PubMed
  210. Escudero-Lara A, et al. 2022. Front Behav Neurosci. 16:946975. PubMed
  211. Wang L, et al. 2017. Front Immunol.. 10.3389/fimmu.2017.01754. PubMed
  212. Fiaturi N, et al. 2018. J Cell Commun Signal. 314:L127. PubMed
  213. Barajas‐Mora EM et al. 2018. Molecular cell. 73(1):48-60 . PubMed
  214. Fujita Y et al. 2018. Cell reports. 24(12):3296-3311 . PubMed
  215. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  216. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  217. Finn J et al. 2019. Cell reports. 26(11):2942-2954 . PubMed
  218. Barger SR, et al. 2019. Nat Commun. 10:1249. PubMed
  219. Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed
  220. Caronni N, et al. 2018. Cancer Res. 78:1685. PubMed
  221. Weiner AI, et al. 2019. NPJ Regen Med. 4:17. PubMed
  222. Russell SL, et al. 2019. Cell Rep. 29:3564. PubMed
  223. Khaw YM, et al. 2020. J Neuroinflammation. 17:49. PubMed
  224. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  225. Damle SR, et al. 2018. Allergy. 73:125. PubMed
  226. Cheng XS, et al. 2020. J Cell Mol Med. 24:8391. PubMed
  227. Kohn M, et al. 2021. Front Immunol. 580594:12. PubMed
  228. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  229. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  230. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  231. Sheller-Miller S, et al. 2021. Sci Adv. 7:. PubMed
  232. Lopez DA, et al. 2022. Cell Rep. 41:111677. PubMed
  233. Ruf B, et al. 2021. Cancer Immunol Res. 9:1024. PubMed
  234. Muñoz NM, et al. 2022. Sci Rep. 12:14449. PubMed
  235. Hu G, et al. 2022. Cell Death Dis. 13:640. PubMed
  236. Sun Y, et al. 2022. Nat Commun. 13:3916. PubMed
  237. MacConmara M, et al. 2011. J Leukoc Biol. 89:137. PubMed
  238. Cassidy LD, et al. 2018. Autophagy. 1.455555556. PubMed
  239. Fransen F, et al. 2017. Front Immunol. 8:154. PubMed
  240. Yang SH, et al. 2017. Front Immunol. 8:1192. PubMed
  241. Lagares D, et al. 2017. Sci Transl Med. 9:eaal3765. PubMed
  242. McLaughlin PA et al. 2019. PLoS Pathog. 15(7):e1007847 . PubMed
  243. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  244. Go MJ, et al. 2018. Mol Med Rep. 13:e0194423. PubMed
  245. McGrath-Morrow S, et al. 2017. Cytokine. 10.1016/j.cyto.2017.06.002. PubMed
  246. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  247. Flommersfeld S, et al. 2021. Immunity. :. PubMed
  248. Wong HS, et al. 2021. Cell. . PubMed
  249. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  250. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  251. Gereke M, et al. 2012. J Vis Exp. 70: 4322. PubMed
  252. Imani J, et al. 2021. JCI Insight. 6:. PubMed
  253. Dang Y, et al. 2021. J Cancer. 12:7158. PubMed
  254. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  255. Pishesha N, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  256. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  257. Hong CH, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:925. PubMed
  258. Csóka B, et al. 2018. JCI Insight. 38:200. PubMed
  259. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  260. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  261. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  262. Hashimoto M, et al. 2019. FASEB J. 33:8069. PubMed
  263. Everard A, et al. 2014. Nat Commun. 5:5648. PubMed
  264. Francis M, et al. 2017. Toxicol Sci. 155(1):182-195. PubMed
  265. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  266. Baasch S, et al. 2021. Cell. . PubMed
  267. Sutherland TE, et al. 2021. Frontiers in Immunology. 12:715209. PubMed
  268. Zheng J, et al. 2020. bioRxiv. . PubMed
  269. Lin C, et al. 2022. Nat Commun. 13:6869. PubMed
  270. De Santi C, et al. 2022. Mol Ther Nucleic Acids. 29:643. PubMed
  271. Pereira M, et al. 2022. Cell Rep. 40:111225. PubMed
  272. Kim S, et al. 2022. Redox Biol. 54:102347. PubMed
  273. Chen Y, et al. 2022. Front Immunol. 13:835690. PubMed
  274. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  275. Welte T, et al. 2021. iScience. 24:103349. PubMed
  276. Moon H, et al. 2020. Nat Commun. 4.270138889. PubMed
  277. Kulkarni U, et al. 2019. Mucosal Immunol. 12:545. PubMed
  278. Tsubaki T, et al. 2018. Oncotarget. 9:11209. PubMed
  279. Qi S et al. 2016. eLife. 5 pii: e14756. PubMed
  280. Roy K, et al. 2019. Immunity. 50:616. PubMed
  281. Baier FA, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:745. PubMed
  282. Li Y, et al. 2021. Sci Transl Med. 13:. PubMed
  283. Dobosz E, et al. 2021. Dis Model Mech. :14. PubMed
  284. Hubbard JJ, et al. 2020. J Exp Med. :217. PubMed
  285. Xu S, et al. 2021. Immunity. . PubMed
  286. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  287. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  288. Duvigneau S, et al. 2016. Sci Rep. 6:37045. PubMed
  289. Siggs O, et al. 2015. Proc Natl Acad Sci U S A. 112: E5706 - E5714. PubMed
  290. Yan W, et al. 2021. Front Med (Lausanne). 8:752223. PubMed
  291. Sun C, et al. 2022. J Adv Res. 35:71. PubMed
  292. Lüönd F, et al. 2022. STAR Protoc. 3:101438. PubMed
  293. Germundson DL, et al. 2022. Front Allergy. 3:870513. PubMed
  294. Sundararaj K, et al. 2021. Immunology. 162:418. PubMed
  295. Jeong M, et al. 2022. JCI Insight. 7:. PubMed
  296. Matsumoto K, et al. 2017. PLoS One. 12(6):e0175406. PubMed
  297. Sauma D, et al. 2017. Immunol Res. 10.1007/s12026-017-8936-9. PubMed
  298. Gil-Pulido J, et al. 2017. PLoS One.. 10.1371/journal.pone.0181947. PubMed
  299. Yu L, et al. 2019. Elife. 8:e46677. PubMed
  300. Chen JC, et al. 2018. Front Immunol. 0.665277778. PubMed
  301. Peng L, et al. 2019. Mol Med Rep. 19:2876. PubMed
  302. Shin J, et al. 2018. Diabetes. 67:1068. PubMed
  303. Dutow P, et al. 2014. J Infect Dis. 209:1269. PubMed
  304. Huang H, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  305. Lehmann GL, et al. 2020. J Exp Med. 217:00:00. PubMed
  306. Zhao L, et al. 2020. EBioMedicine. 60:103020. PubMed
  307. Riedelberger M, et al. 2020. Bio Protoc. e3552:10. PubMed
  308. Chu A, et al. 2021. J Reprod Immunol. 145:103309. PubMed
  309. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  310. Moon S, et al. 2021. J Exp Med. 218:. PubMed
  311. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  312. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  313. Hu CF, et al. 2021. Front Immunol. 12:638381. PubMed
  314. Zheng J, et al. 2020. Nature. . PubMed
  315. Unudurthi SD, et al. 2020. Life Sci. 117440:247. PubMed
  316. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  317. Troutman TD, et al. 2021. STAR Protocols. 2(1):100363. PubMed
  318. Li X, et al. 2020. Nat Commun. 4.877777778. PubMed
  319. Siggs O, et al. 2016. Proc Natl Acad Sci U S A. 113: 3706 - 3715. PubMed
  320. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  321. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  322. Hegde V, et al. 2013. J Biol Chem. 288:36810. PubMed
  323. Tuong ZK, et al. 2021. iScience. 24:103326. PubMed
  324. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  325. Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
  326. Blanchard L, et al. 2022. STAR Protoc. 3:101444. PubMed
  327. Babagana M, et al. 2021. Aging (Albany NY). 13:19207. PubMed
  328. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  329. Enomoto D, et al. 2017. PLoS One.. 10.1371/journal.pone.0183584. PubMed
  330. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  331. Zeng J, et al. 2018. J Immunol. 200:3407. PubMed
  332. Hsu BE et al. 2019. Cell Rep. 27(13):3902-3915 . PubMed
  333. Di Mitri D, et al. 2019. Cell Rep. 28:2156. PubMed
  334. Rebecca S Dickinson et al. 2017. Wellcome open research. 0.155555556 . PubMed
  335. Li B, et al. 2019. Oncol Rep. 41:608. PubMed
  336. Kretschmer L, et al. 2020. Nat Commun. 0.536805556. PubMed
  337. Fujimoto N, et al. 2020. PLoS Biol. 18:e3000704. PubMed
  338. Akk A, et al. 2019. Mol Immunol. 114:629. PubMed
  339. Kmieciak M, et al. 2011. J Vis Exp. 47: 2381. PubMed
  340. Huang BR, et al. 2020. Int J Mol Sci. 21:00. PubMed
  341. Lindborg JA, et al. 2021. Cell Reports. 34(9):108777. PubMed
  342. Ahn D, et al. 2021. Cell Reports. 35(9):109196. PubMed
  343. Matsuda T, et al. 2022. iScience. 25:105324. PubMed
  344. Takahashi F, et al. 2022. iScience. 25:104278. PubMed
  345. Saveljeva S, et al. 2022. Cell Metab. 34:106. PubMed
  346. Zhang YN, et al. 2021. Sci Adv. 7:eabj3107. PubMed
  347. Shibuya M, et al. 2021. iScience. 24:103131. PubMed
  348. Constantinides M, et al. 2011. J Immunol. 187:309. PubMed
  349. Lenert R 2005. J Immunol. 174:2429. PubMed
  350. Ramachandran P, et al. 2019. Nature. 575:512. PubMed
  351. Spranger S, et al. 2017. Cancer Cell. 31:711. PubMed
  352. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  353. Sanchez M et al. 2017. Cell host & microbe. 22(4):543-551 . PubMed
  354. Shibamoto M, et al. 2019. Int Heart J. 60:944. PubMed
  355. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  356. Mohammadi MR, et al. 2021. Commun Biol. 4:685. PubMed
  357. Vilcaes AA, et al. 2020. Int J Mol Sci. :21. PubMed
  358. Zhao L, et al. 2021. STAR Protocols. 2:100732. PubMed
  359. Desai P, et al. 2021. Cell. 184(5):1214-1231.e16. PubMed
  360. Lehmann ML, et al. 2020. Brain Behav Immun. 88:735. PubMed
  361. Xu G, et al. 2020. Cell Rep. 32:108170. PubMed
  362. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  363. Bi J, et al. 2022. Front Microbiol. 13:927122. PubMed
  364. Zhang MH, et al. 2020. Front Immunol. 11:560. PubMed
  365. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  366. López-Sanz C, et al. 2022. STAR Protoc. 3:101755. PubMed
  367. Okuma A, et al. 2017. Nat Commun.. 10.1038/s41467-017-02281-x. PubMed
  368. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  369. Tellechea M, et al. 2018. J Immunol. 200:305. PubMed
  370. Oliveira AC et al. 2017. eLife. 6 pii: e30883. PubMed
  371. Lyle C, et al. 2019. Sci Rep. 9:20257. PubMed
  372. Roussey JA, et al. 2017. J Immunol. 199:3535. PubMed
  373. Mandour MF, et al. 2020. Infect Agent Cancer. 15:30. PubMed
  374. Kolter J, et al. 2020. Immunity. 50(6):1482-1497. PubMed
  375. Nakav S, et al. 2009. Nephrol Dial Transplant. 25:931. PubMed
  376. Miranda-Hernandez S, et al. 2011. J Immunol. 187:791. PubMed
  377. Miura N, et al. 2017. Mol Ther. 10.1016/j.ymthe.2017.01.020. PubMed
  378. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  379. Zhang Y, et al. 2020. Cancer Res. 80:3345. PubMed
  380. Alshetaiwi H, et al. 2020. Methods Mol Biol. 2236:177. PubMed
  381. Ma L, et al. 2022. Sci Adv. 8:eabm3470. PubMed
  382. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  383. Lee SA, et al. 2021. Cells. 10:. PubMed
  384. Ouchi T, et al. 2011. J Exp Med. 208:2607. PubMed
  385. Baumann D, et al. 2020. Nat Commun. 1.969444444. PubMed
  386. Forster R, et al. 2019. FASEB J. 33:11210. PubMed
  387. Heinen A, et al. 2019. Mol Ther. 27:46:00. PubMed
  388. Simmons S et al. 2019. Elife. 8 pii: e41239. PubMed
  389. William M, et al. 2018. J Immunol. 200:4102. PubMed
  390. Contreras NA, et al. 2019. PLoS Pathog. 15:e1007890. PubMed
  391. Miura Y et al. 2018. eLife. 7 pii: e36572. PubMed
  392. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  393. Chida K, et al. 2021. Biol Pharm Bull. 44:1551. PubMed
  394. Saxena M, et al. 2020. Cancer Res. 80:3631. PubMed
  395. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  396. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  397. Magaletta ME, et al. 2022. Nat Commun. 13:457. PubMed
  398. Tzeng TT, et al. 2022. NPJ Vaccines. 7:60. PubMed
  399. Gaya M et al. 2018. Cell. 172(3):517-533 . PubMed
  400. Freeman SA et al. 2018. Cell. 172(1-2):305-317 . PubMed
  401. Glodde N et al. 2017. Immunity. 47(4):789-802 . PubMed
  402. Knox T, et al. 2019. Sci Rep. 9:6136. PubMed
  403. Rojo R, et al. 2019. Nat Commun. 10:3215. PubMed
  404. Schaftenaar FH, et al. 2019. Sci Rep. 9:17391. PubMed
  405. Deng M, et al. 2019. J Exp Med. 216:2838. PubMed
  406. Hong JP, et al. 2020. Cell Reports Medicine. 1(3):100035. PubMed
  407. Clements J, et al. 2006. J Immunol. 177:905. PubMed
  408. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  409. Howe C, et al. 2016. Sci Rep. 6:28699. PubMed
  410. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  411. Senatus L, et al. 2020. JCI Insight. 5:00. PubMed
  412. Matsumoto M, et al. 2021. Cell Host Microbe. 29(6):930-940.e4. PubMed
  413. Jin HS, et al. 2020. Cancer Immunol Res. 8:912. PubMed
  414. Sakurai Y, et al. 2021. Pharmaceutics. 13:. PubMed
  415. Chryplewicz A, et al. 2022. Cancer Cell. 40:1111. PubMed
  416. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  417. Dong H, et al. 2022. Nat Metab. 4:90. PubMed
  418. Penzo M, et al. 2010. J Immunol. 184:4497. PubMed
  419. Mehrpouya-Bahrami P, et al. 2019. J Biol Chem. 294:7669. PubMed
  420. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  421. Blaszczak AM, et al. 2019. J Immunol. 202:2451. PubMed
  422. Sivaram N, et al. 2019. J Clin Invest. 130. PubMed
  423. Litwinoff EMS, et al. 2017. Obes Res Clin Pract. 12:174. PubMed
  424. Burl RB et al. 2018. Cell metabolism. 28(2):300-309 . PubMed
  425. Chetty A, et al. 2021. Cell Host Microbe. 29:579. PubMed
  426. Qiu Z, et al. 2020. Cancer Genet. 245:6. PubMed
  427. Kohn M, et al. 2021. Front Immunol. 626627:12. PubMed
  428. Bonavita E, et al. 2020. Immunity. 1215:53. PubMed
  429. Luo X, et al. 2021. Neuron. 109:2691. PubMed
  430. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  431. Alam MM, et al. 2021. eneuro. 8(1):. PubMed
  432. Sitapara RA, et al. 2020. Mol Med. 26:63. PubMed
  433. Kim K, et al. 2015. Infect Immun . 83:1150. PubMed
  434. Qin J, et al. 2020. Cancer Immunol Res. 8:1426. PubMed
  435. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  436. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  437. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  438. Sibler E, et al. 2022. Cancers (Basel). 14:. PubMed
  439. Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
  440. Lyons DO, et al. 2018. PLoS One. 13:e0207704. PubMed
  441. Li A, et al. 2018. Cancer Lett. 431:54. PubMed
  442. Steinmann S, et al. 2020. Sci Rep. 1.160416667. PubMed
  443. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  444. Melero I, et al. 2015. Cancer Res. 75:497. PubMed
  445. Hegde V, et al. 2015. J Immunol. 194:5211. PubMed
  446. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  447. Goldberg EL, et al. 2021. Cell Metabolism. :. PubMed
  448. Phadke MS, et al. 2021. Cancer Immunol Res. 9:554. PubMed
  449. Sibler E, et al. 2021. Cells. 10:. PubMed
  450. Huanga J, et al. 2013. J Immunol Methods. 387:254. PubMed
  451. Malinczak CA, et al. 2019. J Immunol. 10.4049/jimmunol.1900741. PubMed
  452. Wang X, et al. 2018. Front Immunol. 9:2615. PubMed
  453. Kabir AU, et al. 2018. JCI Insight. 3. PubMed
  454. Buschor S, et al. 2017. PLoS Pathogens. 13(6):e1006476. PubMed
  455. Effern M, et al. 2020. Immunity. 53(3):564-580.e9. PubMed
  456. Liu Q, et al. 2016. Cell Death Dis. 1.93125. PubMed
  457. Richardson M, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
RRID
AB_312800 (BioLegend Cat. No. 101301)
AB_312801 (BioLegend Cat. No. 101302)

Antigen Details

Structure
Ig superfamily, 40-60 kD
Distribution

B cells, monocyte/macrophages, NK cells, neutrophils, mast cells, dendritic cells

Function
Low affinity receptors for IgG
Ligand/Receptor
IgG
Cell Type
B cells, Dendritic cells, Macrophages, Mast cells, Monocytes, Neutrophils, NK cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules, Fc Receptors
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Unkeless JC. 1989. J. Clin. Invest. 83:355.
3. Qiu WQ, et al. 1990. Science 248:732.

Gene ID
14130 View all products for this Gene ID 14131 View all products for this Gene ID
UniProt
View information about CD16/32 on UniProt.org

Related FAQs

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Go To Top Version: 2    Revision Date: 01.23.2015

For Research Use Only. Not for diagnostic or therapeutic use.

 

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