PE anti-mouse/human CD45R/B220 Antibody PE anti-mouse/human CD45R/B220 Antibody

Pricing & Availability
Clone
RA3-6B2 (See other available formats)
Regulatory Status
RUO
Other Names
B220
Isotype
Rat IgG2a, κ
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Product Citations
publications
RA3-6B2_PE_090507
C57BL/6 mouse splenocytes stained with RA3-6B2 PE
  • RA3-6B2_PE_090507
    C57BL/6 mouse splenocytes stained with RA3-6B2 PE
  • RA3-6B2_PE_CD45RB220_Antibody__04292022
    C57BL/6 mouse splenocytes were stained with CD45R/B220 (clone RA3-6B2) PE (solid line) or rat IgG2a, κ PE isotype control (dashed line).

    Data was acquired on the Moxi Flow, exported, and processed using FlowJo software.
Compare all formats See PE spectral data
Cat # Size Price Quantity Check Availability Save
103207 50 µg DKK262
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103208 200 µg DKK636
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Description

CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human
Reported Reactivity
Cat
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Abelson murine leukemia virus-induced pre-B tumor cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone RA3-6B2 has been described to react with an epitope on the extracellular domain of the transmembrane CD45 glycoprotein which is dependent upon the expression of exon A and specific carbohydrate residues. Additional reported applications (for the relevant formats) include: immunoprecipitation1, in vitro and in vivo modulation of B cell responses2-4, immunohistochemistry of acetone-fixed frozen sections and formalin-fixed paraffin-embedded sections5,6, and spatial biology (IBEX)14,15.

Application References
  1. Coffman RL. 1982. Immunol. Rev. 69:5. (IP)
  2. George A, et al. 1994. J. Immunol. 152:1014. (Activ)
  3. Asensi V, et al. 1989. Immunology 68:204. (Activ)
  4. Domiati-Saad R, et al. 1993. J. Immunol. 151:5936. (Activ)
  5. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  6. Monteith CE, et al. 1996. Can. J. Vet. Res. 60:193. (IHC)
  7. Shih FF, et al. 2006. J. Immunol. 176:3438. (FC)
  8. Chang C L-T, et al. 2007. J. Immunol. 178:6984.
  9. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  10. Lang GL, et al. 2008. Blood 111:2158. PubMed
  11. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  12. del Rio ML, et al. 2011. Transpl. Int. 24:501. (FC) PubMed
  13. Murakami R, et al. 2013. PLoS One. 8:73270. PubMed
  14. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  15. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Hiyoshi H, et al. 2022. Cell Host Microbe. 30:163. PubMed
  2. Iberg CA, et al. 2022. Cell Rep. 39:110657. PubMed
  3. Yang K, et al. 2022. Sci Immunol. 7:eabn2888. PubMed
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  6. Liu H, et al. 2022. Cell Rep Med. 3:100660. PubMed
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  9. Lopez R, et al. 2022. Nat Biotechnol. 40:1360. PubMed
  10. Bermea KC, et al. 2022. J Vis Exp. . PubMed
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  14. Ho J, et al. 2016. PLoS Biol. 14:e2000117. PubMed
  15. Tan J, et al. 2021. iScience. 24(8):102835. PubMed
  16. Grigsby SM, et al. 2021. Cancers (Basel). 13:. PubMed
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  19. Gonalves S, et al. 2021. Cell Reports. 34(11):108860. PubMed
  20. Han X, et al. 2017. Int J Mol Sci. 10.3390/ijms18050942. PubMed
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  29. Zape J, et al. 2017. Cell Cycle. 10.1080/15384101.2017.1361569. PubMed
  30. LaFleur MW, et al. 2019. Nat Immunol. 20:1335. PubMed
  31. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
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  33. Papafragkos I, et al. 2022. Front Immunol. 13:889075. PubMed
  34. Sugimoto C, et al. 2022. Elife. 11:. PubMed
  35. Nguyen T, et al. 2014. J Exp Med. 211:1011. PubMed
  36. Cravens P, et al. 2016. PLoS One. 11:e0165248. PubMed
  37. Bartleson JM, et al. 2020. Nat Immunol. 1384:21. PubMed
  38. Lo W, Allen D 2012. Nat Immunol. 13:880. PubMed
  39. Zhang J, et al. 2022. Front Immunol. 13:931740. PubMed
  40. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  41. Artinger K, et al. 2015. PLoS One. 10: 0135087. PubMed
  42. Li J, et al. 2019. JCI Insight. 5. PubMed
  43. Zhang F, et al. 2019. Immunity. 50:738. PubMed
  44. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  45. Tsukasaki M, et al. 2020. Cell Reports. 32(10):108124. PubMed
  46. Kotfis K, et al. 2020. British Journal of Pharmacology. 49(1):66-72. PubMed
  47. Naing A et al. 2019. Cell reports. 26(5):1242-1257 . PubMed
  48. Kang SJ, et al. 2022. Food Sci Anim Resour. 42:903. PubMed
  49. Qiu Z, et al. 2016. Sci Rep. 6:31936. PubMed
  50. Doonan J, et al. 2019. Nat Commun. 10:1554. PubMed
  51. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  52. Hulsmans M et al. 2017. Cell. 169(3):510-522 . PubMed
  53. Onodera T, et al. 2016. J Immunol. 196: 4172 - 4184. PubMed
  54. Venturutti L, et al. 2020. Cell. 182(2):297-316.e27. PubMed
  55. Lasso P, et al. 2020. Front Immunol. 584959:11. PubMed
  56. Khatib–Massalha E, et al. 2020. Nat Commun. 2.921527778. PubMed
  57. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  58. St Clair JB, et al. 2017. PLoS One. 12:e0170556. PubMed
  59. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  60. Nguyen T, et al. 2016. Sci Rep. 6:36906. PubMed
  61. Fu T, et al. 2011. Mol Immunol. 48:751. PubMed
  62. Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
  63. LaFleur MW, et al. 2019. Nat Commun. 10:1668. PubMed
  64. Zhang H, et al. 2019. Mol Cell. 76:110. PubMed
  65. Cho K, et al. 2021. iScience. 24:103117. PubMed
  66. Bourque J, et al. 2021. Heliyon. 7:e08311. PubMed
  67. Alameh MG, et al. 2021. Immunity. 54:2877. PubMed
  68. Germundson DL, et al. 2022. Front Allergy. 3:870513. PubMed
  69. Liu B, et al. 2022. Mol Med Rep. 26:. PubMed
  70. Dagher T, et al. 2021. J Exp Med. 218:. PubMed
  71. White C, et al. 2015. J Immunol. 194:697. PubMed
  72. Lu X, et al. 2015. J Immunol. 194:2011. PubMed
  73. Cook KD, et al. 2015. Immunity. 43:703-714. PubMed
  74. Trefzer A, et al. 2021. Cell Reports. 34(6):108748. PubMed
  75. Zhu X et al. 2019. Cell reports. 27(4):1205-1220 . PubMed
  76. Nagatake T, et al. 2018. Int Immunol. 30:471. PubMed
  77. Uslu M, et al. 2020. J Cell Physiol. 235:9644. PubMed
  78. Murakami K, et al. 2021. Cell Reports. 34(1):108579. PubMed
  79. Walsh SM, et al. 2021. eLife. 10:00. PubMed
  80. Hanihara-Tatsuzawa F, et al. 2014. J Biol Chem. 389:30925. PubMed
  81. Wu T, et al. 2014. J Leukoc Biol. 95:215. PubMed
  82. Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
  83. Schreiber K, et al. 2020. Cancer Immunol Res. 8:192. PubMed
  84. Chen RJ, et al. 2022. iScience. 25:105595. PubMed
  85. Wang H, et al. 2020. Nat Mater. 1.655555556. PubMed
  86. Wang D, et al. 2005. Int Immunol. 1.527083333. PubMed
  87. Kalafati L, et al. 2020. Cell. 183:771. PubMed
  88. Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
  89. Saveljeva S, et al. 2022. Cell Metab. 34:106. PubMed
  90. Liang Q, et al. 2020. Front Microbiol. 11:571847. PubMed
  91. Ha TC, et al. 2020. Hum Gene Ther. 32:458. PubMed
  92. Cai Z, et al. 2020. Cell Rep. 31:107816. PubMed
  93. Lu W, et al. 2016. PLoS One. 11: 0149543. PubMed
  94. Faingold O, et al. 2013. J Biol Chem. 288:32852. PubMed
  95. Xia Y, et al. 2018. Cell. 175:1059. PubMed
  96. Omatsu Y, et al. 2022. Nat Commun. 13:2654. PubMed
  97. Kataru RP, et al. 2022. Front Aging. 3:864860. PubMed
  98. Zhu L, et al. 2022. Cells. 11:. PubMed
  99. Martin R, et al. 2014. PLoS One. 9:110609. PubMed
  100. Chen C, et al. 2020. Front Cell Neurosci. 14:8. PubMed
  101. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  102. Miyauchi K, et al. 2021. Nat Commun. 12:3789. PubMed
  103. Xu C, et al. 2020. Immunity. 53(2):417-428.e4. PubMed
  104. Sebina I, et al. 2016. PLoS Pathog. 12:e1005999. PubMed
  105. Baglaenko Y, et al. 2016. PLoS One. 11: 0150515. PubMed
  106. Golan K et al. 2018. Cell stem cell. 23(4):572-585 . PubMed
  107. Lim J, et al. 2017. Cell. 169:523. PubMed
  108. Hoyer FF, et al. 2020. Immunity. 51(5):899-914.e7.. PubMed
  109. Wu Y, et al. 2015. J Immunol. 195: 2612-2623. PubMed
  110. Montes de Oca M, et al. 2016. PLoS Pathog. 12: 1005398. PubMed
  111. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  112. Matsumoto M, et al. 2021. Cell Host Microbe. 29(6):930-940.e4. PubMed
  113. Rodríguez L, et al. 2021. Biomolecules. 11: . PubMed
  114. Chang C, et al. 2007. J Immunol . 178:6984. PubMed
  115. Platteel ACM, et al. 2018. Front Immunol. 1.544444444. PubMed
  116. Oh B, et al. 2017. Plast Reconstr Surg Glob Open. 5:e1595. PubMed
  117. Katsuyama T, et al. 2019. J Clin Invest. 129:5411. PubMed
  118. Iwanami N, et al. 2020. iScience. 23:101260. PubMed
  119. Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
  120. Le TM et al. 2018. Journal of neurochemistry. 145(2):139-153 . PubMed
  121. Uotila LM, et al. 2017. J Immunol. 199:3644. PubMed
  122. Kanaya T, et al. 2008. Am J Physiol Gastrointest Liver Physiol. 295:273. PubMed
  123. Feng M, et al. 2012. Int Immunopharmacol. 13:135. PubMed
  124. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  125. Gawish R, et al. 2022. Elife. 11:. PubMed
  126. Adachi Y, et al. 2015. J Exp Med. 212: 1709-1723. PubMed
  127. Madsen P, et al. 2016. J Neurosci. 36: 5128 - 5143. PubMed
  128. Heyde A, et al. 2021. Cell. 184(5):1348-1361.e22. PubMed
  129. Evavold CL, et al. 2021. Cell. 184(17):4495-4511.e19. PubMed
  130. Das A, et al. 2020. J Bone Miner Res. 36:199. PubMed
  131. Park CJ, et al. 2020. Cell Reports. 31(2):107496.. PubMed
  132. Zheng QY, et al. 2019. Front Immunol. 10:1866. PubMed
  133. Cabal-Hierro L, et al. 2020. Nat Commun. 11:1406. PubMed
  134. Xiang W, et al. 2020. Signal Transduct Target Ther. 0.374305556. PubMed
  135. Hiyoshi H, et al. 2022. Cell Host Microbe. 30:163. PubMed
  136. Iberg CA, et al. 2022. Cell Rep. 39:110657. PubMed
  137. Yang K, et al. 2022. Sci Immunol. 7:eabn2888. PubMed
  138. Gargaro M, et al. 2022. Immunity. 55:1032. PubMed
  139. Kiani Shabestari S, et al. 2022. Cell Rep. 39:110961. PubMed
  140. Liu H, et al. 2022. Cell Rep Med. 3:100660. PubMed
  141. Albayrak E, et al. 2022. J Cell Biochem. 123:2009. PubMed
  142. Ramdas B, et al. 2022. Mol Ther. 30:2505. PubMed
  143. Lopez R, et al. 2022. Nat Biotechnol. 40:1360. PubMed
  144. Bermea KC, et al. 2022. J Vis Exp. . PubMed
  145. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  146. Huang T, et al. 2023. Cell Death Dis. 14:354. PubMed
  147. Guo H, Cooper S, Friedman A, et al. 2017. PLoS One. 10.1371/journal.pone.0150809. PubMed
  148. Ho J, et al. 2016. PLoS Biol. 14:e2000117. PubMed
  149. Tan J, et al. 2021. iScience. 24(8):102835. PubMed
  150. Grigsby SM, et al. 2021. Cancers (Basel). 13:. PubMed
  151. Baryawno N et al. 2019. Cell. 177(7):1915-1932 . PubMed
  152. Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
  153. Gonalves S, et al. 2021. Cell Reports. 34(11):108860. PubMed
  154. Han X, et al. 2017. Int J Mol Sci. 10.3390/ijms18050942. PubMed
  155. Li Y, et al. 2016. Nat Commun. 7:10836. PubMed
  156. Luo R, et al. 2021. Theranostics. 11:117. PubMed
  157. Ma Z, et al. 2016. Clin Cancer Res. 22: 2969 - 2980. PubMed
  158. Wu R, et al. 2019. J Cell Mol Med. 24:1684. PubMed
  159. Franks SE, et al. 2019. J Immunol. 202:3381. PubMed
  160. Tan X, et al. 2021. Front Oncol. 11:768222. PubMed
  161. Wang X, et al. 2016. PLoS Pathog. 12: 1005367. PubMed
  162. Wong J, et al. 2015. Elife. 3: 07839. PubMed
  163. Zape J, et al. 2017. Cell Cycle. 10.1080/15384101.2017.1361569. PubMed
  164. LaFleur MW, et al. 2019. Nat Immunol. 20:1335. PubMed
  165. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  166. Mathur S, et al. 2021. JCI Insight. 6:. PubMed
  167. Papafragkos I, et al. 2022. Front Immunol. 13:889075. PubMed
  168. Sugimoto C, et al. 2022. Elife. 11:. PubMed
  169. Nguyen T, et al. 2014. J Exp Med. 211:1011. PubMed
  170. Cravens P, et al. 2016. PLoS One. 11:e0165248. PubMed
  171. Bartleson JM, et al. 2020. Nat Immunol. 1384:21. PubMed
  172. Lo W, Allen D 2012. Nat Immunol. 13:880. PubMed
  173. Zhang J, et al. 2022. Front Immunol. 13:931740. PubMed
  174. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  175. Artinger K, et al. 2015. PLoS One. 10: 0135087. PubMed
  176. Li J, et al. 2019. JCI Insight. 5. PubMed
  177. Zhang F, et al. 2019. Immunity. 50:738. PubMed
  178. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  179. Tsukasaki M, et al. 2020. Cell Reports. 32(10):108124. PubMed
  180. Kotfis K, et al. 2020. British Journal of Pharmacology. 49(1):66-72. PubMed
  181. Naing A et al. 2019. Cell reports. 26(5):1242-1257 . PubMed
  182. Kang SJ, et al. 2022. Food Sci Anim Resour. 42:903. PubMed
  183. Qiu Z, et al. 2016. Sci Rep. 6:31936. PubMed
  184. Doonan J, et al. 2019. Nat Commun. 10:1554. PubMed
  185. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  186. Hulsmans M et al. 2017. Cell. 169(3):510-522 . PubMed
  187. Onodera T, et al. 2016. J Immunol. 196: 4172 - 4184. PubMed
  188. Venturutti L, et al. 2020. Cell. 182(2):297-316.e27. PubMed
  189. Lasso P, et al. 2020. Front Immunol. 584959:11. PubMed
  190. Khatib–Massalha E, et al. 2020. Nat Commun. 2.921527778. PubMed
  191. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  192. St Clair JB, et al. 2017. PLoS One. 12:e0170556. PubMed
  193. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  194. Nguyen T, et al. 2016. Sci Rep. 6:36906. PubMed
  195. Fu T, et al. 2011. Mol Immunol. 48:751. PubMed
  196. Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
  197. LaFleur MW, et al. 2019. Nat Commun. 10:1668. PubMed
  198. Zhang H, et al. 2019. Mol Cell. 76:110. PubMed
  199. Cho K, et al. 2021. iScience. 24:103117. PubMed
  200. Bourque J, et al. 2021. Heliyon. 7:e08311. PubMed
  201. Alameh MG, et al. 2021. Immunity. 54:2877. PubMed
  202. Germundson DL, et al. 2022. Front Allergy. 3:870513. PubMed
  203. Liu B, et al. 2022. Mol Med Rep. 26:. PubMed
  204. Dagher T, et al. 2021. J Exp Med. 218:. PubMed
  205. White C, et al. 2015. J Immunol. 194:697. PubMed
  206. Lu X, et al. 2015. J Immunol. 194:2011. PubMed
  207. Cook KD, et al. 2015. Immunity. 43:703-714. PubMed
  208. Trefzer A, et al. 2021. Cell Reports. 34(6):108748. PubMed
  209. Zhu X et al. 2019. Cell reports. 27(4):1205-1220 . PubMed
  210. Nagatake T, et al. 2018. Int Immunol. 30:471. PubMed
  211. Uslu M, et al. 2020. J Cell Physiol. 235:9644. PubMed
  212. Murakami K, et al. 2021. Cell Reports. 34(1):108579. PubMed
  213. Walsh SM, et al. 2021. eLife. 10:00. PubMed
  214. Hanihara-Tatsuzawa F, et al. 2014. J Biol Chem. 389:30925. PubMed
  215. Wu T, et al. 2014. J Leukoc Biol. 95:215. PubMed
  216. Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
  217. Schreiber K, et al. 2020. Cancer Immunol Res. 8:192. PubMed
  218. Chen RJ, et al. 2022. iScience. 25:105595. PubMed
  219. Wang H, et al. 2020. Nat Mater. 1.655555556. PubMed
  220. Wang D, et al. 2005. Int Immunol. 1.527083333. PubMed
  221. Kalafati L, et al. 2020. Cell. 183:771. PubMed
  222. Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
  223. Saveljeva S, et al. 2022. Cell Metab. 34:106. PubMed
  224. Liang Q, et al. 2020. Front Microbiol. 11:571847. PubMed
  225. Ha TC, et al. 2020. Hum Gene Ther. 32:458. PubMed
  226. Cai Z, et al. 2020. Cell Rep. 31:107816. PubMed
  227. Lu W, et al. 2016. PLoS One. 11: 0149543. PubMed
  228. Faingold O, et al. 2013. J Biol Chem. 288:32852. PubMed
  229. Xia Y, et al. 2018. Cell. 175:1059. PubMed
  230. Omatsu Y, et al. 2022. Nat Commun. 13:2654. PubMed
  231. Kataru RP, et al. 2022. Front Aging. 3:864860. PubMed
  232. Zhu L, et al. 2022. Cells. 11:. PubMed
  233. Martin R, et al. 2014. PLoS One. 9:110609. PubMed
  234. Chen C, et al. 2020. Front Cell Neurosci. 14:8. PubMed
  235. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  236. Miyauchi K, et al. 2021. Nat Commun. 12:3789. PubMed
  237. Xu C, et al. 2020. Immunity. 53(2):417-428.e4. PubMed
  238. Sebina I, et al. 2016. PLoS Pathog. 12:e1005999. PubMed
  239. Baglaenko Y, et al. 2016. PLoS One. 11: 0150515. PubMed
  240. Golan K et al. 2018. Cell stem cell. 23(4):572-585 . PubMed
  241. Lim J, et al. 2017. Cell. 169:523. PubMed
  242. Hoyer FF, et al. 2020. Immunity. 51(5):899-914.e7.. PubMed
  243. Wu Y, et al. 2015. J Immunol. 195: 2612-2623. PubMed
  244. Montes de Oca M, et al. 2016. PLoS Pathog. 12: 1005398. PubMed
  245. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  246. Matsumoto M, et al. 2021. Cell Host Microbe. 29(6):930-940.e4. PubMed
  247. Rodríguez L, et al. 2021. Biomolecules. 11: . PubMed
  248. Chang C, et al. 2007. J Immunol . 178:6984. PubMed
  249. Platteel ACM, et al. 2018. Front Immunol. 1.544444444. PubMed
  250. Oh B, et al. 2017. Plast Reconstr Surg Glob Open. 5:e1595. PubMed
  251. Katsuyama T, et al. 2019. J Clin Invest. 129:5411. PubMed
  252. Iwanami N, et al. 2020. iScience. 23:101260. PubMed
  253. Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
  254. Le TM et al. 2018. Journal of neurochemistry. 145(2):139-153 . PubMed
  255. Uotila LM, et al. 2017. J Immunol. 199:3644. PubMed
  256. Kanaya T, et al. 2008. Am J Physiol Gastrointest Liver Physiol. 295:273. PubMed
  257. Feng M, et al. 2012. Int Immunopharmacol. 13:135. PubMed
  258. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  259. Gawish R, et al. 2022. Elife. 11:. PubMed
  260. Adachi Y, et al. 2015. J Exp Med. 212: 1709-1723. PubMed
  261. Madsen P, et al. 2016. J Neurosci. 36: 5128 - 5143. PubMed
  262. Heyde A, et al. 2021. Cell. 184(5):1348-1361.e22. PubMed
  263. Evavold CL, et al. 2021. Cell. 184(17):4495-4511.e19. PubMed
  264. Das A, et al. 2020. J Bone Miner Res. 36:199. PubMed
  265. Park CJ, et al. 2020. Cell Reports. 31(2):107496.. PubMed
  266. Zheng QY, et al. 2019. Front Immunol. 10:1866. PubMed
  267. Cabal-Hierro L, et al. 2020. Nat Commun. 11:1406. PubMed
  268. Xiang W, et al. 2020. Signal Transduct Target Ther. 0.374305556. PubMed
RRID
AB_312992 (BioLegend Cat. No. 103207)
AB_312993 (BioLegend Cat. No. 103208)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

B cells, T cell subset, NK cell subset

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4
Cell Type
B cells, NK cells, T cells
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID 5788 View all products for this Gene ID
UniProt
View information about PTPRC on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.

Other Formats

View All CD45R/B220 Reagents Request Custom Conjugation
Description Clone Applications
PE/Cyanine7 anti-mouse/human CD45R/B220 RA3-6B2 FC
APC/Cyanine7 anti-mouse/human CD45R/B220 RA3-6B2 FC
PE/Dazzle™ 594 anti-mouse/human CD45R/B220 RA3-6B2 FC
APC/Fire™ 750 anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 750™ anti-mouse/human CD45R/B220 RA3-6B2 FC
TotalSeq™-A0103 anti-mouse/human CD45R/B220 RA3-6B2 PG
Spark Blue™ 550 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark NIR™ 685 anti-mouse/human CD45R/B220 RA3-6B2 FC
TotalSeq™-B0103 anti-mouse/human CD45R/B220 RA3-6B2 PG
TotalSeq™-C0103 anti-mouse/human CD45R/B220 RA3-6B2 PG
APC/Fire™ 810 anti-mouse/human CD45R/B220 RA3-6B2 FC
Ultra-LEAF™ Purified anti-mouse/human CD45R/B220 RA3-6B2 FC,CyTOF®,IHC-F,IHC-P,IP,Activ
PE/Fire™ 700 anti-mouse/human CD45R/B220 RA3-6B2 FC
PE/Fire™ 640 anti-mouse/human CD45R/B220 RA3-6B2 FC
Alexa Fluor® 594 anti-mouse/human CD45R/B220 RA3-6B2 IHC-F,FC,3D IHC
APC anti-mouse/human CD45R/B220 RA3-6B2 FC
Biotin anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F
FITC anti-mouse/human CD45R/B220 RA3-6B2 FC
PE anti-mouse/human CD45R/B220 RA3-6B2 FC
PE/Cyanine5 anti-mouse/human CD45R/B220 RA3-6B2 FC
Purified anti-mouse/human CD45R/B220 RA3-6B2 FC,CyTOF®,IHC-F,IHC-P,IP,Activ
Alexa Fluor® 488 anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F,3D IHC
Alexa Fluor® 647 anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F,3D IHC,SB
Pacific Blue™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Alexa Fluor® 700 anti-mouse/human CD45R/B220 RA3-6B2 FC
PerCP anti-mouse/human CD45R/B220 RA3-6B2 FC
PerCP/Cyanine5.5 anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 421™ anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F
Brilliant Violet 570™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 650™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 605™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 785™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 510™ anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F,SB
Brilliant Violet 711™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark Violet™ 538 anti-mouse/human CD45R/B220 RA3-6B2 FC
Purified anti-mouse/human CD45R/B220 (Maxpar® Ready) RA3-6B2 FC,CyTOF®
Spark YG™ 581 anti-mouse/human CD45R/B220 RA3-6B2 FC
PE/Fire™ 810 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark Blue™ 574 anti-mouse/human CD45R/B220 Antibody RA3-6B2 FC
Spark YG™ 570 anti-mouse/human CD45R/B220 RA3-6B2 IHC-F
Spark Violet™ 423 anti-mouse/human CD45R/B220 Antibody RA3-6B2 FC
Spark Red™ 718 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark UV™ 387 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark PLUS UV395™ anti-mouse/human CD45R/B220 RA3-6B2 FC
PerCP/Fire™ 780 anti-mouse/human CD45R/B220 Antibody RA3-6B2 FC
Spark YG™ 593 anti-mouse/human CD45R/B220 (Flexi-Fluor™) Antibody RA3-6B2 FC
Go To Top Version: 2    Revision Date: 04/25/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Pricing & Availability
Clone
RA3-6B2 (See other available formats)
Regulatory Status
RUO
Other Names
B220
Isotype
Rat IgG2a, κ
Ave. Rating
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Product Citations
publications
RA3-6B2_PE_090507
C57BL/6 mouse splenocytes stained with RA3-6B2 PE
  • RA3-6B2_PE_090507
    C57BL/6 mouse splenocytes stained with RA3-6B2 PE
  • RA3-6B2_PE_CD45RB220_Antibody__04292022
    C57BL/6 mouse splenocytes were stained with CD45R/B220 (clone RA3-6B2) PE (solid line) or rat IgG2a, κ PE isotype control (dashed line).

    Data was acquired on the Moxi Flow, exported, and processed using FlowJo software.
Compare all formats See PE spectral data
Cat # Size Price Quantity Check Availability Save
103207 50 µg DKK262
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103208 200 µg DKK636
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Description

CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human
Reported Reactivity
Cat
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Abelson murine leukemia virus-induced pre-B tumor cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone RA3-6B2 has been described to react with an epitope on the extracellular domain of the transmembrane CD45 glycoprotein which is dependent upon the expression of exon A and specific carbohydrate residues. Additional reported applications (for the relevant formats) include: immunoprecipitation1, in vitro and in vivo modulation of B cell responses2-4, immunohistochemistry of acetone-fixed frozen sections and formalin-fixed paraffin-embedded sections5,6, and spatial biology (IBEX)14,15.

Application References
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  2. George A, et al. 1994. J. Immunol. 152:1014. (Activ)
  3. Asensi V, et al. 1989. Immunology 68:204. (Activ)
  4. Domiati-Saad R, et al. 1993. J. Immunol. 151:5936. (Activ)
  5. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  6. Monteith CE, et al. 1996. Can. J. Vet. Res. 60:193. (IHC)
  7. Shih FF, et al. 2006. J. Immunol. 176:3438. (FC)
  8. Chang C L-T, et al. 2007. J. Immunol. 178:6984.
  9. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  10. Lang GL, et al. 2008. Blood 111:2158. PubMed
  11. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  12. del Rio ML, et al. 2011. Transpl. Int. 24:501. (FC) PubMed
  13. Murakami R, et al. 2013. PLoS One. 8:73270. PubMed
  14. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  15. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
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  6. Liu H, et al. 2022. Cell Rep Med. 3:100660. PubMed
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  15. Tan J, et al. 2021. iScience. 24(8):102835. PubMed
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  29. Zape J, et al. 2017. Cell Cycle. 10.1080/15384101.2017.1361569. PubMed
  30. LaFleur MW, et al. 2019. Nat Immunol. 20:1335. PubMed
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  35. Nguyen T, et al. 2014. J Exp Med. 211:1011. PubMed
  36. Cravens P, et al. 2016. PLoS One. 11:e0165248. PubMed
  37. Bartleson JM, et al. 2020. Nat Immunol. 1384:21. PubMed
  38. Lo W, Allen D 2012. Nat Immunol. 13:880. PubMed
  39. Zhang J, et al. 2022. Front Immunol. 13:931740. PubMed
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  43. Zhang F, et al. 2019. Immunity. 50:738. PubMed
  44. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  45. Tsukasaki M, et al. 2020. Cell Reports. 32(10):108124. PubMed
  46. Kotfis K, et al. 2020. British Journal of Pharmacology. 49(1):66-72. PubMed
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  48. Kang SJ, et al. 2022. Food Sci Anim Resour. 42:903. PubMed
  49. Qiu Z, et al. 2016. Sci Rep. 6:31936. PubMed
  50. Doonan J, et al. 2019. Nat Commun. 10:1554. PubMed
  51. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
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  53. Onodera T, et al. 2016. J Immunol. 196: 4172 - 4184. PubMed
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  135. Hiyoshi H, et al. 2022. Cell Host Microbe. 30:163. PubMed
  136. Iberg CA, et al. 2022. Cell Rep. 39:110657. PubMed
  137. Yang K, et al. 2022. Sci Immunol. 7:eabn2888. PubMed
  138. Gargaro M, et al. 2022. Immunity. 55:1032. PubMed
  139. Kiani Shabestari S, et al. 2022. Cell Rep. 39:110961. PubMed
  140. Liu H, et al. 2022. Cell Rep Med. 3:100660. PubMed
  141. Albayrak E, et al. 2022. J Cell Biochem. 123:2009. PubMed
  142. Ramdas B, et al. 2022. Mol Ther. 30:2505. PubMed
  143. Lopez R, et al. 2022. Nat Biotechnol. 40:1360. PubMed
  144. Bermea KC, et al. 2022. J Vis Exp. . PubMed
  145. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  146. Huang T, et al. 2023. Cell Death Dis. 14:354. PubMed
  147. Guo H, Cooper S, Friedman A, et al. 2017. PLoS One. 10.1371/journal.pone.0150809. PubMed
  148. Ho J, et al. 2016. PLoS Biol. 14:e2000117. PubMed
  149. Tan J, et al. 2021. iScience. 24(8):102835. PubMed
  150. Grigsby SM, et al. 2021. Cancers (Basel). 13:. PubMed
  151. Baryawno N et al. 2019. Cell. 177(7):1915-1932 . PubMed
  152. Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
  153. Gonalves S, et al. 2021. Cell Reports. 34(11):108860. PubMed
  154. Han X, et al. 2017. Int J Mol Sci. 10.3390/ijms18050942. PubMed
  155. Li Y, et al. 2016. Nat Commun. 7:10836. PubMed
  156. Luo R, et al. 2021. Theranostics. 11:117. PubMed
  157. Ma Z, et al. 2016. Clin Cancer Res. 22: 2969 - 2980. PubMed
  158. Wu R, et al. 2019. J Cell Mol Med. 24:1684. PubMed
  159. Franks SE, et al. 2019. J Immunol. 202:3381. PubMed
  160. Tan X, et al. 2021. Front Oncol. 11:768222. PubMed
  161. Wang X, et al. 2016. PLoS Pathog. 12: 1005367. PubMed
  162. Wong J, et al. 2015. Elife. 3: 07839. PubMed
  163. Zape J, et al. 2017. Cell Cycle. 10.1080/15384101.2017.1361569. PubMed
  164. LaFleur MW, et al. 2019. Nat Immunol. 20:1335. PubMed
  165. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  166. Mathur S, et al. 2021. JCI Insight. 6:. PubMed
  167. Papafragkos I, et al. 2022. Front Immunol. 13:889075. PubMed
  168. Sugimoto C, et al. 2022. Elife. 11:. PubMed
  169. Nguyen T, et al. 2014. J Exp Med. 211:1011. PubMed
  170. Cravens P, et al. 2016. PLoS One. 11:e0165248. PubMed
  171. Bartleson JM, et al. 2020. Nat Immunol. 1384:21. PubMed
  172. Lo W, Allen D 2012. Nat Immunol. 13:880. PubMed
  173. Zhang J, et al. 2022. Front Immunol. 13:931740. PubMed
  174. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  175. Artinger K, et al. 2015. PLoS One. 10: 0135087. PubMed
  176. Li J, et al. 2019. JCI Insight. 5. PubMed
  177. Zhang F, et al. 2019. Immunity. 50:738. PubMed
  178. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  179. Tsukasaki M, et al. 2020. Cell Reports. 32(10):108124. PubMed
  180. Kotfis K, et al. 2020. British Journal of Pharmacology. 49(1):66-72. PubMed
  181. Naing A et al. 2019. Cell reports. 26(5):1242-1257 . PubMed
  182. Kang SJ, et al. 2022. Food Sci Anim Resour. 42:903. PubMed
  183. Qiu Z, et al. 2016. Sci Rep. 6:31936. PubMed
  184. Doonan J, et al. 2019. Nat Commun. 10:1554. PubMed
  185. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  186. Hulsmans M et al. 2017. Cell. 169(3):510-522 . PubMed
  187. Onodera T, et al. 2016. J Immunol. 196: 4172 - 4184. PubMed
  188. Venturutti L, et al. 2020. Cell. 182(2):297-316.e27. PubMed
  189. Lasso P, et al. 2020. Front Immunol. 584959:11. PubMed
  190. Khatib–Massalha E, et al. 2020. Nat Commun. 2.921527778. PubMed
  191. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  192. St Clair JB, et al. 2017. PLoS One. 12:e0170556. PubMed
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RRID
AB_312992 (BioLegend Cat. No. 103207)
AB_312993 (BioLegend Cat. No. 103208)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

B cells, T cell subset, NK cell subset

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4
Cell Type
B cells, NK cells, T cells
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID 5788 View all products for this Gene ID
UniProt
View information about PTPRC on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.

Other Formats

View All CD45R/B220 Reagents Request Custom Conjugation
Description Clone Applications
PE/Cyanine7 anti-mouse/human CD45R/B220 RA3-6B2 FC
APC/Cyanine7 anti-mouse/human CD45R/B220 RA3-6B2 FC
PE/Dazzle™ 594 anti-mouse/human CD45R/B220 RA3-6B2 FC
APC/Fire™ 750 anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 750™ anti-mouse/human CD45R/B220 RA3-6B2 FC
TotalSeq™-A0103 anti-mouse/human CD45R/B220 RA3-6B2 PG
Spark Blue™ 550 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark NIR™ 685 anti-mouse/human CD45R/B220 RA3-6B2 FC
TotalSeq™-B0103 anti-mouse/human CD45R/B220 RA3-6B2 PG
TotalSeq™-C0103 anti-mouse/human CD45R/B220 RA3-6B2 PG
APC/Fire™ 810 anti-mouse/human CD45R/B220 RA3-6B2 FC
Ultra-LEAF™ Purified anti-mouse/human CD45R/B220 RA3-6B2 FC,CyTOF®,IHC-F,IHC-P,IP,Activ
PE/Fire™ 700 anti-mouse/human CD45R/B220 RA3-6B2 FC
PE/Fire™ 640 anti-mouse/human CD45R/B220 RA3-6B2 FC
Alexa Fluor® 594 anti-mouse/human CD45R/B220 RA3-6B2 IHC-F,FC,3D IHC
APC anti-mouse/human CD45R/B220 RA3-6B2 FC
Biotin anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F
FITC anti-mouse/human CD45R/B220 RA3-6B2 FC
PE anti-mouse/human CD45R/B220 RA3-6B2 FC
PE/Cyanine5 anti-mouse/human CD45R/B220 RA3-6B2 FC
Purified anti-mouse/human CD45R/B220 RA3-6B2 FC,CyTOF®,IHC-F,IHC-P,IP,Activ
Alexa Fluor® 488 anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F,3D IHC
Alexa Fluor® 647 anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F,3D IHC,SB
Pacific Blue™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Alexa Fluor® 700 anti-mouse/human CD45R/B220 RA3-6B2 FC
PerCP anti-mouse/human CD45R/B220 RA3-6B2 FC
PerCP/Cyanine5.5 anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 421™ anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F
Brilliant Violet 570™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 650™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 605™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 785™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 510™ anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F,SB
Brilliant Violet 711™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark Violet™ 538 anti-mouse/human CD45R/B220 RA3-6B2 FC
Purified anti-mouse/human CD45R/B220 (Maxpar® Ready) RA3-6B2 FC,CyTOF®
Spark YG™ 581 anti-mouse/human CD45R/B220 RA3-6B2 FC
PE/Fire™ 810 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark Blue™ 574 anti-mouse/human CD45R/B220 Antibody RA3-6B2 FC
Spark YG™ 570 anti-mouse/human CD45R/B220 RA3-6B2 IHC-F
Spark Violet™ 423 anti-mouse/human CD45R/B220 Antibody RA3-6B2 FC
Spark Red™ 718 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark UV™ 387 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark PLUS UV395™ anti-mouse/human CD45R/B220 RA3-6B2 FC
PerCP/Fire™ 780 anti-mouse/human CD45R/B220 Antibody RA3-6B2 FC
Spark YG™ 593 anti-mouse/human CD45R/B220 (Flexi-Fluor™) Antibody RA3-6B2 FC
Go To Top Version: 2    Revision Date: 04/25/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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