Product specifications and manufacturing guidelines include:

Our CD3 and CD28 antibodies are optimized for T cell activation and expansion in ex vivo cell culture applications. They are offered as Ultra-Low Endotoxin, Serum-Free (Ultra-LEAF™) antibody formulation to facilitate in vivo as well as in vitro experiments. We manufacture monoclonal antibodies Cell-Vive™ GMP Ultra-LEAF™ Purified anti-human CD3 SF Antibody (clone OKT3) and GMP Ultra-LEAF™ Purified anti-human CD28 SF Antibody (clones S20013F and CD28.2) under serum-free (SF) animal component-free conditions. This feature is important because animal-derived components, such as fetal bovine serum (FBS), are heterogeneous in nature, which negatively impacts lot-to-lot product consistency. 

CD34 markers are expressed on immature hematopoietic stem/progenitor cells (HSPCs) and downregulated as early stem cells differentiate into mature cells. This expression pattern of CD34 suggests that it plays a significant role in early hematopoiesis. Cell-Vive™ GMP Ultra-LEAF™ Purified anti-human CD34 SF Antibody is suitable for research and further ex vivo cell processing, making it ideal to identify and isolate HSPCs as well as for cell analysis to gauge cell recovery and functionality.

Our GMP Ultra-LEAF™ Purified anti-human HLA-A,B,C SF Antibody is also ideal for use in research and further ex vivo bioprocessing, HLA I molecules are part of MHC class I system that present foreign-derived peptides to cytotoxic CD8⁺ T cells, thus playing an important role in cell-mediated immune responses and tumor surveillance.

Isolate pure T cell populations with our ultra-low endotoxin, serum-free (SF) biotinylated antibodies. Our GMP Ultra-LEAF Biotin anti-human CD3 SF Antibody and GMP Ultra-LEAF Biotin anti-human CD28 SF Antibody are ideal to optimize T cell separation and characterization.

Our representative data highlights Cell-Vive GMP MojoSort Streptavidin Nanobeads that contain streptavidin on their surface to harness the high affinity binding of biotin-conjugated antibodies for positive or negative selection of targeted cells.