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Purified anti-mouse CD16/32 Antibody

Pricing & Availability
Clone
93 (See other available formats)
Regulatory Status
RUO
Other Names
Fcγ R III/II, Ly-17
Isotype
Rat IgG2a, λ
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Product Citations
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93_purified_051906
C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
  • 93_purified_051906
    C57BL/6 mouse splenocytes stained with purified 93, followed by anti-rat IgGs FITC
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101301 50 µg £25
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101302 500 µg £79
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Description

CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Sorted pre-B cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The CD16/32 antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IP, Block - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone 93 can be used for blocking of CD16/CD32 interactions with the Fc domain of immunoglobulins, but is not the same clone as 2.4G2.

The 93 mAb is specific to the common epitope of CD16/CD32. Additional reported applications (for the relevant formats) include: immunoprecipitation1 and blocking of Fc-mediated reactions in functional studies2,4,23. It is useful for blocking non-specific binding of immunoglobulin to Fc receptors. For blocking of Fc receptors in flow cytometric analysis, pre-incubate the cells with purified anti-CD16/CD32 antibody (=1.0 µg per 106 cells in 100 µL volume) for 5-10 minutes on ice prior to immunostaining. For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 101330) (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered).

Application References

(PubMed link indicates BioLegend citation)
  1. Personal communication (IP)
  2. Oliver AM, et al. 1999. Hybridoma 18:113. (Block)
  3. Brummel R and Lenert P. 2005. J. Immunol. 174:2429.
  4. Terrazas LI, et al. 2005. Int. J. Parasitol. 35:1349. (Block)
  5. Clements JL, et al. 2006. J. Immunol. 177:905.
  6. Mohamed W, et al. 2010. Infect Immun. 78:3306. PubMed
  7. Ouchi T, et al. 2011. J. Exp Med. 208:2607. PubMed
  8. Kmieciak M, et al. 2011. J. Vis. Exp. 47:2381. PubMed
  9. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  10. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  11. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  12. Koon HW, et al. 2013. J. Vis. Exp. 68:4208. PubMed
  13. Hegde VL, et al. 2013. J Biol Chem. 288:36810. PubMed
  14. Huang J, et al. 2013. J. Immunol Methods. 387:254. PubMed
  15. Dutow P, et al. 2014. J Infect Dis. PubMed
  16. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  17. Huang HN, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  18. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  19. Richardson ML, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  20. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  21. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  22. Everad A, et al. 2014. Nat Commun. 5:5648. PubMed
  23. Cenci E, et al. 2006. J. Leuko. Biol. 79(1):40-5. (Block)
Product Citations
  1. Sade-Feldman M,et al. 2017. Nat Commun.. 10.1038/s41467-017-01062-w. PubMed
  2. Michela Miani et al. 2018. Cell metabolism. 28(4):557-572 . PubMed
  3. Gan T, et al. 2019. Front Microbiol. 9:3174. PubMed
  4. Furuhashi K, et al. 2017. Immunology. 151:227. PubMed
  5. Fomin ME, et al. 2017. Cell Med. 0.45625. PubMed
  6. Jebbawi F, et al. 2021. Parasite Immunol. 43:e12834. PubMed
  7. Thomas R, et al. 2021. Immunology. 163:478. PubMed
  8. Herz J, et al. 2021. Neuron. 109:3609. PubMed
  9. Li H, et al. 2022. Cancer Cell. 40:36. PubMed
  10. Glynn RA, et al. 2022. J Immunol. 208:371. PubMed
  11. Kozuki S, et al. 2022. Genes Cells. 27:192. PubMed
  12. Bettke JA, et al. 2022. Infect Immun. 90:e0007022. PubMed
  13. Guttman O, et al. 2022. J Cell Biol. 221: . PubMed
  14. Miyao T, et al. 2022. Elife. 11: . PubMed
  15. Yin K, et al. 2022. Genes Dev. 36:533. PubMed
  16. Malhi H, et al. 2022. Cell Rep Med. 3:100658. PubMed
  17. Zhang Y, et al. 2022. Vaccines (Basel). 10: . PubMed
  18. Sugimoto S, et al. 2022. Nat Metab. 4:775. PubMed
  19. Hong Y, et al. 2022. J Leukoc Biol. 112:425. PubMed
  20. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  21. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  22. Akalu YT, et al. 2022. Elife. 11: . PubMed
  23. Zhang X, et al. 2022. EBioMedicine. 84:104275. PubMed
  24. Bottermann K, et al. 2022. Basic Res Cardiol. 117:48. PubMed
  25. Hao J, et al. 2022. Cell Rep. 41:111804. PubMed
  26. McNamara NB, et al. 2023. Nature. 613:120. PubMed
  27. Miró L, et al. 2022. Cancers (Basel). 14: . PubMed
  28. Liu P, et al. 2023. Clin Immunol. 246:109212. PubMed
  29. Ullah I, et al. 2023. Cell Rep Med. 4:100893. PubMed
  30. Al-Saafeen BH, et al. 2023. Front Immunol. 13:1017780. PubMed
  31. Cousin N, et al. 2022. Cells. 12: . PubMed
  32. Peng Q, et al. 2023. EMBO Rep. 24:e56034. PubMed
  33. Tichet M, et al. 2023. Immunity. 56:162. PubMed
  34. Zhou H, et al. 2023. Front Immunol. 13:1059687. PubMed
  35. Mandour MF, et al. 2023. Front Med (Lausanne). 9:1057252. PubMed
  36. Kemna J, et al. 2023. Nat Immunol. 24:414. PubMed
  37. Novaj A, et al. 2023. Int J Mol Sci. 24: . PubMed
  38. Ishikawa T, et al. 2023. Bio Protoc. 13:e4588. PubMed
  39. Liu X, et al. 2022. Pain. 163:508. PubMed
  40. Zhang M, et al. 2022. Mol Imaging Biol. 24:280. PubMed
  41. Zhang W, et al. 2022. Dev Cell. 57:329. PubMed
  42. Kodali S, et al. 2022. J Immunol. 208:1085. PubMed
  43. Chen K, et al. 2022. Adv Sci (Weinh). 9:e2104106. PubMed
  44. Zhang H, et al. 2022. Nat Cancer. 3:808. PubMed
  45. Fang Y, et al. 2022. Sci Immunol. 7:eabp9962. PubMed
  46. Koch MS, et al. 2022. Mol Ther Oncolytics. 26:275. PubMed
  47. Harapas CR, et al. 2022. Sci Immunol. 7:eabi4611. PubMed
  48. Ding P, et al. 2022. Elife. 11:. PubMed
  49. Deák P, et al. 2022. Cell Rep. 41:111563. PubMed
  50. Zhong J, et al. 2022. J Adv Res. 41:145. PubMed
  51. Melo-Silva CR, et al. 2022. Cell Rep. 41:111676. PubMed
  52. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  53. Wu Q, et al. 2023. Front Immunol. 13:1081719. PubMed
  54. Li L, et al. 2023. iScience. 26:106095. PubMed
  55. Torrente D, et al. 2023. J Neuroinflammation. 20:56. PubMed
  56. Bai X, et al. 2023. Nat Commun. 14:1247. PubMed
  57. Rocca Y, et al. 2023. Methods Mol Biol. 2618:187. PubMed
  58. Dang YZ, et al. 2023. Neoplasma. 70:123. PubMed
  59. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  60. Kudo T, et al. 2023. iScience. 26:106342. PubMed
  61. Liu KY, et al. 2023. Environ Health Perspect. 131:37014. PubMed
  62. Zhang YN, et al. 2023. Nat Commun. 14:1985. PubMed
  63. Iguchi A, et al. 2023. iScience. 26:106375. PubMed
  64. Feng Y, et al. 2023. J Transl Med. 21:290. PubMed
  65. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  66. Liu JC, et al. 2023. Int J Mol Sci. 24:. PubMed
  67. Petenkova A, et al. 2023. Nat Commun. 14:2761. PubMed
  68. Xu J, et al. 2023. Discov Oncol. 14:68. PubMed
  69. An R, et al. 2022. Cell Insight. 1:100047. PubMed
  70. Wang K, et al. 2023. Nat Commun. 14:2950. PubMed
  71. Amirova KM, et al. 2023. Int J Mol Sci. 24:. PubMed
  72. Li M, et al. 2023. BMC Cancer. 23:497. PubMed
  73. Mawambo G, et al. 2023. J Neuroinflammation. 20:145. PubMed
  74. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  75. Rajagopalan A, et al. 2021. Cell Rep Methods. 1:. PubMed
  76. Guo H, et al. 2020. Curr Protoc Immunol. 131:e107. PubMed
  77. Van Braeckel-Budimir N, et al. 2021. J Immunother Cancer. 9:. PubMed
  78. Wang Z, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  79. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  80. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  81. Cerrato G, et al. 2021. Cell Death Differ. 28:1733. PubMed
  82. Da Mesquita S, et al. 2021. Nature. 593:255. PubMed
  83. Liu C, et al. 2022. Nat Nanotechnol. 17:531. PubMed
  84. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  85. Chida J, et al. 2020. PLoS Pathog. 16:e1008823. PubMed
  86. Iyer S, et al. 2021. Cancer Discov. 0.725. PubMed
  87. Park E, et al. 2021. Journal of Neuroscience Research. . PubMed
  88. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  89. Kosti P, et al. 2021. Cell Reports Medicine. 2(4):100227. PubMed
  90. Barkaway A, et al. 2021. Immunity. . PubMed
  91. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  92. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  93. Foster A, et al. 2021. EBioMedicine. 71:103571. PubMed
  94. Kiepura A, et al. 2021. Int J Mol Sci. 22:. PubMed
  95. Lee J, et al. 2015. Hum Reprod. 10.1093/humrep/dev222. PubMed
  96. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  97. Filippini D, et al. 2019. Sci Rep. 9:12286. PubMed
  98. Flamar AL, et al. 2020. Immunity. 52(4):606-619.e6.. PubMed
  99. Biljes D, et al. 2017. EXCLI J. 0.86875. PubMed
  100. Zhang R, et al. 2019. Cell Rep. 28:2647. PubMed
  101. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  102. Zou B, et al. 2017. PLoS Pathogens. 13(6):e1006436. PubMed
  103. Kitagawa S, et al. 2022. NPJ Vaccines. 7:115. PubMed
  104. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  105. Yu Y, et al. 2022. iScience. 25:105004. PubMed
  106. Huang Y, et al. 2021. Nat Immunol. 22:586. PubMed
  107. MacLean M, et al. 2022. Commun Biol. 5:177. PubMed
  108. Effern M, et al. 2022. STAR Protoc. 3:101038. PubMed
  109. Rødahl I, et al. 2021. STAR Protoc. 2:100842. PubMed
  110. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
  111. Wong Fok Lung T, et al. 2020. Nat Microbiol. 141:5. PubMed
  112. Qian Y, et al. 2021. Cell Reports. 36(8):109602. PubMed
  113. Benitez AA, et al. 2020. Commun Biol. 0.371527778. PubMed
  114. Castoldi Â, et al. 2020. Nat Commun. 3.310416667. PubMed
  115. Mevel R, et al. 2020. eLife. 9:00. PubMed
  116. Fan Y, et al. 2014. J Exp Med. 211:313. PubMed
  117. Berry CT, et al. 2020. Cell Reports. 31(2):107474.. PubMed
  118. Rendeiro AF, et al. 2020. Nat Commun. 11:577. PubMed
  119. Tan H,et al. 2017. Mucosal Immunol. . 10.1038/mi.2017.89. PubMed
  120. Clarke F,et al. 2017. PLoS One. 10.1371/journal.pone.0186625. PubMed
  121. Postat J et al. 2018. Immunity. 49(4):654-665 . PubMed
  122. Minutti CM, et al. 2019. Immunity. 50:645. PubMed
  123. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  124. Takeda Y, et al. 2018. Innate Immun. 24:323. PubMed
  125. Goel S, et al. 2017. Nature. 548:471. PubMed
  126. Matsui S, et al. 2018. Am J Pathol. 188:2059. PubMed
  127. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  128. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  129. Khamissi FZ, et al. 2022. Sci Adv. 8:eabm5900. PubMed
  130. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  131. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  132. Feng J, et al. 2021. iScience. 24:103004. PubMed
  133. Wu L, et al. 2022. Front Immunol. 13:860761. PubMed
  134. Browning D, et al. 2017. Gene Ther. 10.1038/gt.2016.88. PubMed
  135. Morris MG, et al. 2020. Comp Med. 70:336. PubMed
  136. Sano T, et al. 2021. Cell Reports. 36:109608. PubMed
  137. Martos-Rus C, et al. 2021. Sci Rep. 11:2974. PubMed
  138. Liu P, et al. 2021. Front Med (Lausanne). 8:625130. PubMed
  139. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  140. Weng L, et al. 2016. Sci Rep. 6:38632. PubMed
  141. Bhatia D, et al. 2019. JCI Insight. 4:e132826. PubMed
  142. Noh JR, et al. 2018. Sci Rep. 8:15222. PubMed
  143. Flores M, et al. 2008. FASEB J. 3.459027778. PubMed
  144. Tong J, et al. 2011. J Immunol. 186:3686. PubMed
  145. Gawden‐Bone CM et al. 2018. Immunity. 49(3):427-437 . PubMed
  146. Tyagi AM et al. 2018. Immunity. 49(6):1116-1131 . PubMed
  147. Oyarce C, et al. 2018. Front Immunol. 8:1794. PubMed
  148. Diao L, et al. 2022. iScience. 25:105511. PubMed
  149. Zhang Y, et al. 2022. Cancers (Basel). 14:. PubMed
  150. Mirshahi F, et al. 2022. Cell Rep. 38:110454. PubMed
  151. Sun SJ, et al. 2022. Commun Biol. 5:867. PubMed
  152. Chen X, et al. 2021. Cell Death Differ. 28:1237. PubMed
  153. Roberto Raúl SG, et al. 2022. Breast Cancer (Auckl). 16:11782234211065154. PubMed
  154. Matthias J, et al. 2020. J Clin Invest. 130:4587. PubMed
  155. Menzel L, et al. 2021. Cell Rep. 37:109878. PubMed
  156. Liang F, et al. 2021. Front Immunol. 12:658715. PubMed
  157. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  158. Clark AL, et al. 2021. Diabetes Obesity and Metabolism. :. PubMed
  159. Stahnke S, et al. 2021. Current Biology. 31(10):2051-2064.e8. PubMed
  160. Yang SB, et al. 2021. Cancers (Basel). 13:00. PubMed
  161. Elisabeth Schrumpf, Xiaojun Jiang 2017. Physiol Rep. 10.14814/phy2.13117. PubMed
  162. Koon H, et al. 2012. J Vis Exp. 68: 4208. PubMed
  163. Azuma M, et al. 2012. Oncoimmunology. 1:581. PubMed
  164. Yamazaki S, et al. 2012. PLoS One. 7:e51665. PubMed
  165. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  166. Hays C, et al. 2020. eLife. 8:e48772.. PubMed
  167. Li Y, et al. 2020. Cell Rep. 30:1753. PubMed
  168. Nakagawa S et al. 2017. Cell host & microbe. 22(5):667-677 . PubMed
  169. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
  170. Fiala GJ, et al. 2019. J Immunol. 203:569. PubMed
  171. Dave K et al. 2017. eLife. 6 pii: e23382. PubMed
  172. Kitashima DY, et al. 2018. EBioMedicine. 27:293. PubMed
  173. Li Y, et al. 2018. J Immunol. 201:2910. PubMed
  174. Shen H, et al. 2022. Nat Commun. 13:6030. PubMed
  175. Armaka M, et al. 2022. Genome Med. 14:78. PubMed
  176. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  177. Hazama D, et al. 2020. Cell Chemical Biology. 27(9):1181-1191.e7. PubMed
  178. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  179. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  180. Okuniewska M, et al. 2021. Cell Reports. 36(2):109368. PubMed
  181. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  182. Webster HC, et al. 2020. J Immunol Methods. 112702:477. PubMed
  183. Godbersen-Palmer C, et al. 2020. J Immunol. 204:2973. PubMed
  184. Yang C, et al. 2020. J Control Release. 326:324. PubMed
  185. Liu D, et al. 2021. JCI Insight. 6:. PubMed
  186. Carlson P, et al. 2019. Nat Cell Biol. 21:238. PubMed
  187. Wu J, et al. 2020. Sci Adv. 6:eaba3458. PubMed
  188. Guan H, et al. 2012. PLoS One. 7:e35650. PubMed
  189. Sereni L, et al. 2018. J Allergy Clin Immunol. 142:1272. PubMed
  190. Fransen F, et al. 2017. Front Immunol. 1.295138889. PubMed
  191. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  192. Wlodarska M et al. 2017. Cell host & microbe. 22(1):25-37 . PubMed
  193. Wang Y, et al. 2022. Front Immunol. 13:767630. PubMed
  194. Ma J, et al. 2021. Aging (Albany NY). 13:7211. PubMed
  195. Yu M, et al. 2021. J Clin Invest. 131:. PubMed
  196. Cousin N, et al. 2021. Cancer Res. 81:4133. PubMed
  197. Haugh KA, et al. 2021. eLife. 0.416666666666667. PubMed
  198. Tal MC, et al. 2020. MBio. 11:00. PubMed
  199. Zhang X, et al. 2020. J Immunol. 205:1743. PubMed
  200. Kovacs L, et al. 2020. PLoS One. 15:e0240455. PubMed
  201. Vackova J, et al. 2020. Int J Mol Sci. 21:00. PubMed
  202. Terrazas LI, et al. 2005. Int J Parasit. 35:1349. PubMed
  203. Bhattacherjee A, et al. 2019. Commun Biol. 2:450. PubMed
  204. Lieschke S, et al. 2019. Cells. 0.420833333. PubMed
  205. Wang L, et al. 2017. Front Immunol.. 10.3389/fimmu.2017.01754. PubMed
  206. Fiaturi N, et al. 2018. J Cell Commun Signal. 314:L127. PubMed
  207. Barajas‐Mora EM et al. 2018. Molecular cell. 73(1):48-60 . PubMed
  208. Fujita Y et al. 2018. Cell reports. 24(12):3296-3311 . PubMed
  209. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  210. Koliaraki V et al. 2019. Cell reports. 26(3):536-545 . PubMed
  211. Finn J et al. 2019. Cell reports. 26(11):2942-2954 . PubMed
  212. Barger SR, et al. 2019. Nat Commun. 10:1249. PubMed
  213. Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed
  214. Caronni N, et al. 2018. Cancer Res. 78:1685. PubMed
  215. Escudero-Lara A, et al. 2022. Front Behav Neurosci. 16:946975. PubMed
  216. Mao W, et al. 2021. Int J Mol Sci. 22:. PubMed
  217. Dang Y, et al. 2022. Cancer Cell Int. 22:88. PubMed
  218. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  219. Cong M, et al. 2021. Methods Mol Biol. 2388:59. PubMed
  220. Menzel L, et al. 2022. STAR Protoc. 3:101267. PubMed
  221. Cheng XS, et al. 2020. J Cell Mol Med. 24:8391. PubMed
  222. Kohn M, et al. 2021. Front Immunol. 580594:12. PubMed
  223. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  224. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  225. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  226. Sheller-Miller S, et al. 2021. Sci Adv. 7:. PubMed
  227. Weiner AI, et al. 2019. NPJ Regen Med. 4:17. PubMed
  228. Russell SL, et al. 2019. Cell Rep. 29:3564. PubMed
  229. Khaw YM, et al. 2020. J Neuroinflammation. 17:49. PubMed
  230. Chen C, et al. 2019. Cell Rep. 29:4200. PubMed
  231. Damle SR, et al. 2018. Allergy. 73:125. PubMed
  232. Lagares D, et al. 2017. Sci Transl Med. 9:eaal3765. PubMed
  233. McLaughlin PA et al. 2019. PLoS Pathog. 15(7):e1007847 . PubMed
  234. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  235. Go MJ, et al. 2018. Mol Med Rep. 13:e0194423. PubMed
  236. McGrath-Morrow S, et al. 2017. Cytokine. 10.1016/j.cyto.2017.06.002. PubMed
  237. Lopez DA, et al. 2022. Cell Rep. 41:111677. PubMed
  238. Ruf B, et al. 2021. Cancer Immunol Res. 9:1024. PubMed
  239. Muñoz NM, et al. 2022. Sci Rep. 12:14449. PubMed
  240. Hu G, et al. 2022. Cell Death Dis. 13:640. PubMed
  241. Sun Y, et al. 2022. Nat Commun. 13:3916. PubMed
  242. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  243. Flommersfeld S, et al. 2021. Immunity. :. PubMed
  244. Wong HS, et al. 2021. Cell. . PubMed
  245. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  246. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  247. Gereke M, et al. 2012. J Vis Exp. 70: 4322. PubMed
  248. MacConmara M, et al. 2011. J Leukoc Biol. 89:137. PubMed
  249. Cassidy LD, et al. 2018. Autophagy. 1.455555556. PubMed
  250. Fransen F, et al. 2017. Front Immunol. 8:154. PubMed
  251. Yang SH, et al. 2017. Front Immunol. 8:1192. PubMed
  252. Csóka B, et al. 2018. JCI Insight. 38:200. PubMed
  253. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  254. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  255. Imani J, et al. 2021. JCI Insight. 6:. PubMed
  256. Dang Y, et al. 2021. J Cancer. 12:7158. PubMed
  257. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  258. Pishesha N, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  259. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  260. Hong CH, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:925. PubMed
  261. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  262. Baasch S, et al. 2021. Cell. . PubMed
  263. Sutherland TE, et al. 2021. Frontiers in Immunology. 12:715209. PubMed
  264. Zheng J, et al. 2020. bioRxiv. . PubMed
  265. Everard A, et al. 2014. Nat Commun. 5:5648. PubMed
  266. Francis M, et al. 2017. Toxicol Sci. 155(1):182-195. PubMed
  267. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  268. Hashimoto M, et al. 2019. FASEB J. 33:8069. PubMed
  269. Qi S et al. 2016. eLife. 5 pii: e14756. PubMed
  270. Roy K, et al. 2019. Immunity. 50:616. PubMed
  271. Lin C, et al. 2022. Nat Commun. 13:6869. PubMed
  272. De Santi C, et al. 2022. Mol Ther Nucleic Acids. 29:643. PubMed
  273. Pereira M, et al. 2022. Cell Rep. 40:111225. PubMed
  274. Kim S, et al. 2022. Redox Biol. 54:102347. PubMed
  275. Chen Y, et al. 2022. Front Immunol. 13:835690. PubMed
  276. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  277. Welte T, et al. 2021. iScience. 24:103349. PubMed
  278. Baier FA, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:745. PubMed
  279. Li Y, et al. 2021. Sci Transl Med. 13:. PubMed
  280. Dobosz E, et al. 2021. Dis Model Mech. :14. PubMed
  281. Hubbard JJ, et al. 2020. J Exp Med. :217. PubMed
  282. Xu S, et al. 2021. Immunity. . PubMed
  283. Tacconi C, et al. 2021. Cell Reports. 35(2):108993. PubMed
  284. Dieterich LC, et al. 2020. Angiogenesis. 1.24375. PubMed
  285. Duvigneau S, et al. 2016. Sci Rep. 6:37045. PubMed
  286. Siggs O, et al. 2015. Proc Natl Acad Sci U S A. 112: E5706 - E5714. PubMed
  287. Moon H, et al. 2020. Nat Commun. 4.270138889. PubMed
  288. Kulkarni U, et al. 2019. Mucosal Immunol. 12:545. PubMed
  289. Tsubaki T, et al. 2018. Oncotarget. 9:11209. PubMed
  290. Matsumoto K, et al. 2017. PLoS One. 12(6):e0175406. PubMed
  291. Sauma D, et al. 2017. Immunol Res. 10.1007/s12026-017-8936-9. PubMed
  292. Gil-Pulido J, et al. 2017. PLoS One.. 10.1371/journal.pone.0181947. PubMed
  293. Yu L, et al. 2019. Elife. 8:e46677. PubMed
  294. Chen JC, et al. 2018. Front Immunol. 0.665277778. PubMed
  295. Jeong M, et al. 2022. JCI Insight. 7:. PubMed
  296. Yan W, et al. 2021. Front Med (Lausanne). 8:752223. PubMed
  297. Sun C, et al. 2022. J Adv Res. 35:71. PubMed
  298. Lüönd F, et al. 2022. STAR Protoc. 3:101438. PubMed
  299. Germundson DL, et al. 2022. Front Allergy. 3:870513. PubMed
  300. Sundararaj K, et al. 2021. Immunology. 162:418. PubMed
  301. Lehmann GL, et al. 2020. J Exp Med. 217:00:00. PubMed
  302. Zhao L, et al. 2020. EBioMedicine. 60:103020. PubMed
  303. Riedelberger M, et al. 2020. Bio Protoc. e3552:10. PubMed
  304. Dutow P, et al. 2014. J Infect Dis. 209:1269. PubMed
  305. Huang H, et al. 2014. Antimicrob Agents Chemother. 58:1538. PubMed
  306. Peng L, et al. 2019. Mol Med Rep. 19:2876. PubMed
  307. Shin J, et al. 2018. Diabetes. 67:1068. PubMed
  308. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  309. Chu A, et al. 2021. J Reprod Immunol. 145:103309. PubMed
  310. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  311. Moon S, et al. 2021. J Exp Med. 218:. PubMed
  312. Hu CF, et al. 2021. Front Immunol. 12:638381. PubMed
  313. Zheng J, et al. 2020. Nature. . PubMed
  314. Unudurthi SD, et al. 2020. Life Sci. 117440:247. PubMed
  315. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  316. Troutman TD, et al. 2021. STAR Protocols. 2(1):100363. PubMed
  317. Li X, et al. 2020. Nat Commun. 4.877777778. PubMed
  318. Siggs O, et al. 2016. Proc Natl Acad Sci U S A. 113: 3706 - 3715. PubMed
  319. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  320. Cekanaviciute E, et al. 2014. J Immunol. 193:139. PubMed
  321. Hegde V, et al. 2013. J Biol Chem. 288:36810. PubMed
  322. Kyburz A, et al. 2019. J Allergy Clin Immunol. 143:1496. PubMed
  323. Enomoto D, et al. 2017. PLoS One.. 10.1371/journal.pone.0183584. PubMed
  324. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  325. Zeng J, et al. 2018. J Immunol. 200:3407. PubMed
  326. Hsu BE et al. 2019. Cell Rep. 27(13):3902-3915 . PubMed
  327. Di Mitri D, et al. 2019. Cell Rep. 28:2156. PubMed
  328. Rebecca S Dickinson et al. 2017. Wellcome open research. 0.155555556 . PubMed
  329. Li B, et al. 2019. Oncol Rep. 41:608. PubMed
  330. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  331. Tuong ZK, et al. 2021. iScience. 24:103326. PubMed
  332. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  333. Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
  334. Blanchard L, et al. 2022. STAR Protoc. 3:101444. PubMed
  335. Babagana M, et al. 2021. Aging (Albany NY). 13:19207. PubMed
  336. Huang BR, et al. 2020. Int J Mol Sci. 21:00. PubMed
  337. Lindborg JA, et al. 2021. Cell Reports. 34(9):108777. PubMed
  338. Ahn D, et al. 2021. Cell Reports. 35(9):109196. PubMed
  339. Kmieciak M, et al. 2011. J Vis Exp. 47: 2381. PubMed
  340. Kretschmer L, et al. 2020. Nat Commun. 0.536805556. PubMed
  341. Fujimoto N, et al. 2020. PLoS Biol. 18:e3000704. PubMed
  342. Akk A, et al. 2019. Mol Immunol. 114:629. PubMed
  343. Sanchez M et al. 2017. Cell host & microbe. 22(4):543-551 . PubMed
  344. Shibamoto M, et al. 2019. Int Heart J. 60:944. PubMed
  345. Matsuda T, et al. 2022. iScience. 25:105324. PubMed
  346. Takahashi F, et al. 2022. iScience. 25:104278. PubMed
  347. Saveljeva S, et al. 2022. Cell Metab. 34:106. PubMed
  348. Zhang YN, et al. 2021. Sci Adv. 7:eabj3107. PubMed
  349. Shibuya M, et al. 2021. iScience. 24:103131. PubMed
  350. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  351. Mohammadi MR, et al. 2021. Commun Biol. 4:685. PubMed
  352. Vilcaes AA, et al. 2020. Int J Mol Sci. :21. PubMed
  353. Zhao L, et al. 2021. STAR Protocols. 2:100732. PubMed
  354. Desai P, et al. 2021. Cell. 184(5):1214-1231.e16. PubMed
  355. Lehmann ML, et al. 2020. Brain Behav Immun. 88:735. PubMed
  356. Xu G, et al. 2020. Cell Rep. 32:108170. PubMed
  357. Takei S, et al. 2014. Vaccine. 32:3066. PubMed
  358. Constantinides M, et al. 2011. J Immunol. 187:309. PubMed
  359. Lenert R 2005. J Immunol. 174:2429. PubMed
  360. Ramachandran P, et al. 2019. Nature. 575:512. PubMed
  361. Spranger S, et al. 2017. Cancer Cell. 31:711. PubMed
  362. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  363. Okuma A, et al. 2017. Nat Commun.. 10.1038/s41467-017-02281-x. PubMed
  364. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  365. Tellechea M, et al. 2018. J Immunol. 200:305. PubMed
  366. Oliveira AC et al. 2017. eLife. 6 pii: e30883. PubMed
  367. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  368. López-Sanz C, et al. 2022. STAR Protoc. 3:101755. PubMed
  369. Bi J, et al. 2022. Front Microbiol. 13:927122. PubMed
  370. Zhang MH, et al. 2020. Front Immunol. 11:560. PubMed
  371. Miura N, et al. 2017. Mol Ther. 10.1016/j.ymthe.2017.01.020. PubMed
  372. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  373. Zhang Y, et al. 2020. Cancer Res. 80:3345. PubMed
  374. Lyle C, et al. 2019. Sci Rep. 9:20257. PubMed
  375. Roussey JA, et al. 2017. J Immunol. 199:3535. PubMed
  376. Mandour MF, et al. 2020. Infect Agent Cancer. 15:30. PubMed
  377. Kolter J, et al. 2020. Immunity. 50(6):1482-1497. PubMed
  378. Nakav S, et al. 2009. Nephrol Dial Transplant. 25:931. PubMed
  379. Miranda-Hernandez S, et al. 2011. J Immunol. 187:791. PubMed
  380. Heinen A, et al. 2019. Mol Ther. 27:46:00. PubMed
  381. Simmons S et al. 2019. Elife. 8 pii: e41239. PubMed
  382. William M, et al. 2018. J Immunol. 200:4102. PubMed
  383. Contreras NA, et al. 2019. PLoS Pathog. 15:e1007890. PubMed
  384. Miura Y et al. 2018. eLife. 7 pii: e36572. PubMed
  385. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  386. Alshetaiwi H, et al. 2020. Methods Mol Biol. 2236:177. PubMed
  387. Ma L, et al. 2022. Sci Adv. 8:eabm3470. PubMed
  388. Leary N, et al. 2022. J Extracell Vesicles. 11:e12197. PubMed
  389. Lee SA, et al. 2021. Cells. 10:. PubMed
  390. Chida K, et al. 2021. Biol Pharm Bull. 44:1551. PubMed
  391. Saxena M, et al. 2020. Cancer Res. 80:3631. PubMed
  392. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  393. Ouchi T, et al. 2011. J Exp Med. 208:2607. PubMed
  394. Baumann D, et al. 2020. Nat Commun. 1.969444444. PubMed
  395. Forster R, et al. 2019. FASEB J. 33:11210. PubMed
  396. Gaya M et al. 2018. Cell. 172(3):517-533 . PubMed
  397. Freeman SA et al. 2018. Cell. 172(1-2):305-317 . PubMed
  398. Glodde N et al. 2017. Immunity. 47(4):789-802 . PubMed
  399. Knox T, et al. 2019. Sci Rep. 9:6136. PubMed
  400. Rojo R, et al. 2019. Nat Commun. 10:3215. PubMed
  401. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  402. Magaletta ME, et al. 2022. Nat Commun. 13:457. PubMed
  403. Tzeng TT, et al. 2022. NPJ Vaccines. 7:60. PubMed
  404. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  405. Senatus L, et al. 2020. JCI Insight. 5:00. PubMed
  406. Matsumoto M, et al. 2021. Cell Host Microbe. 29(6):930-940.e4. PubMed
  407. Jin HS, et al. 2020. Cancer Immunol Res. 8:912. PubMed
  408. Sakurai Y, et al. 2021. Pharmaceutics. 13:. PubMed
  409. Kimura T, et al. 2014. Int Immunol. 26:697. PubMed
  410. Howe C, et al. 2016. Sci Rep. 6:28699. PubMed
  411. Schaftenaar FH, et al. 2019. Sci Rep. 9:17391. PubMed
  412. Deng M, et al. 2019. J Exp Med. 216:2838. PubMed
  413. Hong JP, et al. 2020. Cell Reports Medicine. 1(3):100035. PubMed
  414. Clements J, et al. 2006. J Immunol. 177:905. PubMed
  415. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  416. Blaszczak AM, et al. 2019. J Immunol. 202:2451. PubMed
  417. Sivaram N, et al. 2019. J Clin Invest. 130. PubMed
  418. Litwinoff EMS, et al. 2017. Obes Res Clin Pract. 12:174. PubMed
  419. Burl RB et al. 2018. Cell metabolism. 28(2):300-309 . PubMed
  420. Chryplewicz A, et al. 2022. Cancer Cell. 40:1111. PubMed
  421. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  422. Dong H, et al. 2022. Nat Metab. 4:90. PubMed
  423. Chetty A, et al. 2021. Cell Host Microbe. 29:579. PubMed
  424. Qiu Z, et al. 2020. Cancer Genet. 245:6. PubMed
  425. Kohn M, et al. 2021. Front Immunol. 626627:12. PubMed
  426. Bonavita E, et al. 2020. Immunity. 1215:53. PubMed
  427. Luo X, et al. 2021. Neuron. 109:2691. PubMed
  428. McDonald MM, et al. 2021. Cell. 184(5):1330-1347.e13. PubMed
  429. Alam MM, et al. 2021. eneuro. 8(1):. PubMed
  430. Sitapara RA, et al. 2020. Mol Med. 26:63. PubMed
  431. Kim K, et al. 2015. Infect Immun . 83:1150. PubMed
  432. Penzo M, et al. 2010. J Immunol. 184:4497. PubMed
  433. Mehrpouya-Bahrami P, et al. 2019. J Biol Chem. 294:7669. PubMed
  434. Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
  435. Lyons DO, et al. 2018. PLoS One. 13:e0207704. PubMed
  436. Li A, et al. 2018. Cancer Lett. 431:54. PubMed
  437. Qin J, et al. 2020. Cancer Immunol Res. 8:1426. PubMed
  438. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  439. Zhang M, et al. 2022. iScience. 25:104490. PubMed
  440. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  441. Sibler E, et al. 2022. Cancers (Basel). 14:. PubMed
  442. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  443. Goldberg EL, et al. 2021. Cell Metabolism. :. PubMed
  444. Phadke MS, et al. 2021. Cancer Immunol Res. 9:554. PubMed
  445. Sibler E, et al. 2021. Cells. 10:. PubMed
  446. Li J, et al. 2012. Arthritis Rheum. 64:1098. PubMed
  447. Melero I, et al. 2015. Cancer Res. 75:497. PubMed
  448. Hegde V, et al. 2015. J Immunol. 194:5211. PubMed
  449. Steinmann S, et al. 2020. Sci Rep. 1.160416667. PubMed
  450. Malinczak CA, et al. 2019. J Immunol. 10.4049/jimmunol.1900741. PubMed
  451. Wang X, et al. 2018. Front Immunol. 9:2615. PubMed
  452. Kabir AU, et al. 2018. JCI Insight. 3. PubMed
  453. Buschor S, et al. 2017. PLoS Pathogens. 13(6):e1006476. PubMed
  454. Effern M, et al. 2020. Immunity. 53(3):564-580.e9. PubMed
  455. Liu Q, et al. 2016. Cell Death Dis. 1.93125. PubMed
  456. Richardson M, et al. 2014. PLoS Negl Trop Dis. 8:2825. PubMed
  457. Huanga J, et al. 2013. J Immunol Methods. 387:254. PubMed
RRID
AB_312800 (BioLegend Cat. No. 101301)
AB_312801 (BioLegend Cat. No. 101302)

Antigen Details

Structure
Ig superfamily, 40-60 kD
Distribution

B cells, monocyte/macrophages, NK cells, neutrophils, mast cells, dendritic cells

Function
Low affinity receptors for IgG
Ligand/Receptor
IgG
Cell Type
B cells, Dendritic cells, Macrophages, Mast cells, Monocytes, Neutrophils, NK cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules, Fc Receptors
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Unkeless JC. 1989. J. Clin. Invest. 83:355.
3. Qiu WQ, et al. 1990. Science 248:732.

Gene ID
14130 View all products for this Gene ID 14131 View all products for this Gene ID
UniProt
View information about CD16/32 on UniProt.org

Related FAQs

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Go To Top Version: 2    Revision Date: 01/23/2015

For Research Use Only. Not for diagnostic or therapeutic use.

 

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