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APC anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
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Product Citations
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30-F11_APC_090507
C57BL/6 mouse splenocytes stained with 30-F11 APC
  • 30-F11_APC_090507
    C57BL/6 mouse splenocytes stained with 30-F11 APC
Compare all formats See APC spectral data
Cat # Size Price Quantity Check Availability Save
103111 25 µg 27€
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103112 100 µg 76€
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Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Application References
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Strickley JD, et al. 2019. Nature. 575:519. PubMed
  2. Kuo PC, et al. 2021. Brain Commun. 3:fcab187. PubMed
  3. Nigam S, et al. 2020. Mol Imaging Biol. 22:685. PubMed
  4. Yang D, et al. 2022. Cell. 185:1905. PubMed
  5. Jiang Z, et al. 2021. J Clin Invest. 131: . PubMed
  6. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  7. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  8. Gavin KM, et al. 2018. Front Endocrinol (Lausanne). 9:276. PubMed
  9. Wang L, et al. 2018. Bone Res. 6:22. PubMed
  10. Cha JH et al. 2018. Molecular cell. 71(4):606-620 . PubMed
  11. Haimon Z et al. 2018. Nature immunology. 19(6):636-644 . PubMed
  12. Ying W, et al. 2019. Cell Metab. 29:457. PubMed
  13. Witherel CE, et al. 2021. Biomaterials. 269:120667. PubMed
  14. Kozuki S, et al. 2022. Genes Cells. 27:192. PubMed
  15. Cautivo KM, et al. 2022. Immunity. 55:254. PubMed
  16. Liang X, et al. 2022. Cancer Commun (Lond). 42:205. PubMed
  17. Lloyd-Lewis B, et al. 2022. Cell Rep. 38:110461. PubMed
  18. Yang Y, et al. 2022. FEBS J. 289:5279. PubMed
  19. MacLean AJ, et al. 2022. Immunity. 55:718. PubMed
  20. Yousefi M, et al. 2022. Cancer Res. 82:1589. PubMed
  21. Van Deren DA, et al. 2022. Development. 149: . PubMed
  22. Lee R, et al. 2022. Cancer Discov. 12:1702. PubMed
  23. Jiang W, et al. 2022. FASEB J. 36:e22294. PubMed
  24. Wang S, et al. 2022. Sci Adv. 8:eabn3883. PubMed
  25. Wu TJ, et al. 2022. Cell Mol Life Sci. 79:348. PubMed
  26. Malhi H, et al. 2022. Cell Rep Med. 3:100658. PubMed
  27. Campisi L, et al. 2022. Nature. 606:945. PubMed
  28. Ma Z, et al. 2022. Theranostics. 12:4965. PubMed
  29. Richards M, et al. 2022. Elife. 11: . PubMed
  30. Gao Y, et al. 2022. Cell Res. 32:1086. PubMed
  31. Ge Y, et al. 2022. iScience. 25:105437. PubMed
  32. Liang Y, et al. 2022. Theranostics. 12:7729. PubMed
  33. Cattaneo P, et al. 2022. Nat Commun. 13:7444. PubMed
  34. Wang H, et al. 2022. J Nanobiotechnology. 20:513. PubMed
  35. Kuo CS, et al. 2022. Elife. 11: . PubMed
  36. Ge Y, et al. 2022. STAR Protoc. 4:101936. PubMed
  37. Yu J, et al. 2022. Nat Commun. 13:7903. PubMed
  38. Urata S, et al. 2023. Microbiol Immunol. 67:105. PubMed
  39. Al-Saafeen BH, et al. 2023. Front Immunol. 13:1017780. PubMed
  40. Hu R, et al. 2023. Cell Death Discov. 9:50. PubMed
  41. Wang L, et al. 2023. Oxid Med Cell Longev. 2023:6480848. PubMed
  42. Dragan M, et al. 2022. J Invest Dermatol. 142:583. PubMed
  43. Wei J, et al. 2022. Cancer Prev Res (Phila). 15:285. PubMed
  44. Yang Z, et al. 2022. J Nucl Med. 63:1708. PubMed
  45. Xin DQ, et al. 2022. Neural Regen Res. 17:2238. PubMed
  46. Li DD, et al. 2022. Cell Host Microbe. 30:530. PubMed
  47. Bohrer AC, et al. 2022. Cell Rep. 40:111144. PubMed
  48. Yu L, et al. 2022. Cancer Sci. 113:3980. PubMed
  49. Kuo A, et al. 2022. Elife. 11:. PubMed
  50. Chen LC, et al. 2023. Immunology. 169:271. PubMed
  51. Wilson NG, et al. 2023. iScience. 26:105991. PubMed
  52. Peng YJ, et al. 2023. Development. 150:. PubMed
  53. Wang JX, et al. 2023. JCI Insight. 8:. PubMed
  54. Pioli KT, et al. 2023. iScience. 26:106223. PubMed
  55. Wu Y, et al. 2023. Nat Cancer. 4:382. PubMed
  56. Henn RE, et al. 2023. iScience. 26:106164. PubMed
  57. Barberio AE, et al. 2023. Bioeng Transl Med. 8:e10453. PubMed
  58. Kawai H, et al. 2023. JBMR Plus. 7:e10722. PubMed
  59. Tan X, et al. 2023. Adv Sci (Weinh). 10:e2206768. PubMed
  60. Palakurthi B, et al. 2023. Nat Commun. 14:2109. PubMed
  61. Yao H, et al. 2023. Front Immunol. 14:1147674. PubMed
  62. Hernandez VG, et al. 2023. Glia. 71:1960. PubMed
  63. Liu H, et al. 2023. Breast Cancer Res. 25:43. PubMed
  64. Petenkova A, et al. 2023. Nat Commun. 14:2761. PubMed
  65. Abdelwahab T, et al. 2023. iScience. 26:106698. PubMed
  66. Shao X, et al. 2023. Cell Discov. 9:44. PubMed
  67. Vereertbrugghen A, et al. 2023. J Neuroinflammation. 20:120. PubMed
  68. Kalgudde Gopal S, et al. 2023. Nat Commun. 14:3020. PubMed
  69. Li M, et al. 2023. BMC Cancer. 23:497. PubMed
  70. Tan L, et al. 2022. Aging Dis. 13:1562. PubMed
  71. Mourao L, et al. 2019. Sci Rep. 0.991666667. PubMed
  72. Bouchareychas L, et al. 2021. iScience. 24(8):102847. PubMed
  73. Almada AE, et al. 2021. Cell Reports. 34(4):108656. PubMed
  74. Kim JS, et al. 2020. Immunity. 54(1):176-190.e7. PubMed
  75. Garcia-Fabiani MB, et al. 2020. Methods Enzymol. 632:369. PubMed
  76. Jaiswal AK, et al. 2020. Immunobiology. 225:151956. PubMed
  77. Cayre S, et al. 2020. Development. 147:00:00. PubMed
  78. Díaz NM, et al. 2020. Invest Ophthalmol Vis Sci. 61:37:00. PubMed
  79. Oetjen LK et al. 2017. Cell. 171(1):217-228 . PubMed
  80. Testini C, et al. 2019. EMBO Rep. 20:e47845. PubMed
  81. Gao Q, et al. 2019. J Exp Med. 216:688. PubMed
  82. Shavit Stein E, et al. 2018. Neural Plast. 2018:7692182. PubMed
  83. Kang I, et al. 2012. Blood. 119:3295. PubMed
  84. Wang Y, et al. 2021. J Bone Oncol. 30:100386. PubMed
  85. Lu L, et al. 2022. Sci Rep. 12:931. PubMed
  86. Parhiz H, et al. 2022. J Control Release. 344:50. PubMed
  87. Yu K, et al. 2021. Cell Reports. 35(12):109273. PubMed
  88. Lim JT, et al. 2020. Mol Cancer Ther. 1809:19. PubMed
  89. Rosa FF, et al. 2020. Bio Protoc. 10:e3619. PubMed
  90. Karlen SJ, et al. 2018. J Neuroinflammation. 15:344. PubMed
  91. Du Q, et al. 2019. Front Microbiol. 10:2050. PubMed
  92. Ahmed M, et al. 2016. Development. 143: 1663 - 1673. PubMed
  93. Engelbrecht E, et al. 2020. eLife. 9:e52690.. PubMed
  94. Hays C, et al. 2020. eLife. 8:e48772.. PubMed
  95. Zhang Y, et al. 2022. Cancers (Basel). 14:. PubMed
  96. Barwe SP, et al. 2022. J Clin Med. 11:. PubMed
  97. Tilstam PV, et al. 2021. J Clin Invest. 131:. PubMed
  98. Yu X, et al. 2021. Nature. 594:560. PubMed
  99. Sato S, et al. 2021. Int J Mol Sci. 22:. PubMed
  100. Oliva Chávez AS, et al. 2021. Nat Commun. 12:3696. PubMed
  101. Yanagida K, et al. 2020. Dev Cell. 779:52. PubMed
  102. Hirano KI, et al. 2021. eLife. 0.416666666666667. PubMed
  103. Larouche JA, et al. 2021. eLife. 0.416666666666667. PubMed
  104. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  105. Barberio AE, et al. 2020. ACS Nano. 14:11238. PubMed
  106. Lechner AJ et al. 2017. Cell stem cell. 21(1):120-134 . PubMed
  107. Chen J, et al. 2022. Nat Commun. 13:6759. PubMed
  108. Wang S, et al. 2022. Front Immunol. 13:869061. PubMed
  109. Chiche A, et al. 2016. Oncogene. 10.1038/onc.2016.396. PubMed
  110. Eastman A, et al. 2016. J Immunol . 194: 5999-6010. PubMed
  111. Romagnoli M, et al. 2020. Development. 147:. PubMed
  112. Li Q, et al. 2021. Brain Behav Immun. 94:437. PubMed
  113. Wang X, et al. 2022. Nat Aging. 2:155. PubMed
  114. Wang T, et al. 2020. Blood Sci. 2:79. PubMed
  115. Strunz M, et al. 2020. Nat Commun. 2.929861111. PubMed
  116. Shemer A, et al. 2020. Immunity. 53(5):1033-1049.e7. PubMed
  117. Schiller M, et al. 2021. Immunity. 54(5):1022-1036.e8. PubMed
  118. Wosczyna MN, et al. 2021. Cell Stem Cell. 28(7):1323-1334.e8. PubMed
  119. Okuniewska M, et al. 2021. Cell Reports. 36(2):109368. PubMed
  120. Zhao B, et al. 2021. Cell Reports. 36(3):109401. PubMed
  121. Motoyama S, et al. 2020. Cells. :9. PubMed
  122. Park JA, et al. 2021. J Hematol Oncol. 14:142. PubMed
  123. Jin X, et al. 2019. Mol Cell. 73:22:00. PubMed
  124. Duarte N, et al. 2018. Hepatol Commun. 0.833333333. PubMed
  125. Pelletier A, et al. 2012. J Immunol. 188:5561. PubMed
  126. Herting CJ, et al. 2019. Brain. 142:3834. PubMed
  127. Romagnoli M, et al. 2019. Stem Cell Reports. 1.077083333. PubMed
  128. Xu X, et al. 2021. J Nanobiotechnology. 19:376. PubMed
  129. Bourn JR, et al. 2021. Cancer Lett. 503:75. PubMed
  130. Khateb M, et al. 2022. Cell Rep. 40:111219. PubMed
  131. Xu Q, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  132. Liu K, et al. 2022. Theranostics. 12:639. PubMed
  133. Sato Y, et al. 2021. J Clin Invest. Online ahead of print. PubMed
  134. Lv H, et al. 2020. Cell Metabolism. 33(1):110-127.e5. PubMed
  135. Amouyal C, et al. 2020. EBioMedicine. 58:102895. PubMed
  136. Ning X, et al. 2019. Mol Cell. 74:19. PubMed
  137. De S, et al. 2018. Development. 145. PubMed
  138. Xiao X, et al. 2019. Cell Discov. 5:2. PubMed
  139. Mauduit O, et al. 2022. Front Immunol. 13:1011125. PubMed
  140. Chen Z, et al. 2022. Theranostics. 12:6242. PubMed
  141. Liu L, et al. 2015. Neurol Neuroimmunol Neuroinflamm. 2: 174. PubMed
  142. Hyatt L, et al. 2014. PLoS One. 9:109072. PubMed
  143. Sambasivan R, et al. 2011. Development. 138:3647. PubMed
  144. Palathingal Bava E, et al. 2022. JCI Insight. 7:. PubMed
  145. Ma S, et al. 2021. Cell Reports. 34(6):108726. PubMed
  146. Ankawa R, et al. 2021. Developmental Cell. . PubMed
  147. Hu EY, et al. 2021. Blood Adv. 5:3152. PubMed
  148. An J,et al. 2017. Sci Rep.. 10.1038/s41598-017-13629-0. PubMed
  149. Wosczyna MN et al. 2019. Cell Rep. 27(7):2029-2035 . PubMed
  150. Maston LD, et al. 2017. Am J Physiol Lung Cell Mol Physiol. 312:L609. PubMed
  151. Bresson L, et al. 2018. Development. 145. PubMed
  152. Charmsaz S, et al. 2017. Leukemia. 31:1779. PubMed
  153. Lafkas D, et al. 2013. J Cell Biol. 203:47. PubMed
  154. Kotfis K, et al. 2020. British Journal of Pharmacology. 49(1):66-72. PubMed
  155. Fischer A, et al. 2022. Nat Immunol. 23:518. PubMed
  156. Hu J, et al. 2022. Cell Mol Neurobiol. . PubMed
  157. Chen L, et al. 2021. Cell Death Differ. 28:1880. PubMed
  158. Shcherbina A, et al. 2020. Cell Rep. 32:107964. PubMed
  159. Wu J, et al. 2020. Immunity. 53:115. PubMed
  160. Frii J, et al. 2021. Immunity. 54(5):1002-1021.e10. PubMed
  161. Alshetaiwi H, et al. 2020. Sci Immunol. 5:00. PubMed
  162. Xiao P, et al. 2019. J Exp Med. 216:337. PubMed
  163. Varol D et al. 2017. Immunity. 46(6):1030-1044 . PubMed
  164. Chen X et al. 2017. Cell stem cell. 21(6):747-760 . PubMed
  165. Zheng B, et al. 2018. J Hematol Oncol. 11:16. PubMed
  166. Pal B, et al. 2017. Nat Commun.. 10.1038/s41467-017-01560-x. PubMed
  167. Hou M, et al. 2020. Stem Cell Res Ther. 11:55. PubMed
  168. Hanasoge Somasundara AV, et al. 2021. Cell Rep. 37:110099. PubMed
  169. Thinard R, et al. 2022. Pharmaceutics. 14:. PubMed
  170. Yang H, et al. 2022. Nutrients. 14:. PubMed
  171. Hu J, et al. 2022. J Neuroinflammation. 19:71. PubMed
  172. Xie Z, et al. 2020. Light Sci Appl. 0.486805556. PubMed
  173. Morimoto A, et al. 2021. Nat Commun. 12:2136. PubMed
  174. Yuan Z, et al. 2018. Emerg Microbes Infect. 7:59. PubMed
  175. Pezoldt J, et al. 2022. Nat Commun. 13:7227. PubMed
  176. Dudek KA, et al. 2020. Proc Natl Acad Sci U S A. 117:3326. PubMed
  177. Yang J, et al. 2022. Microbiome. 10:149. PubMed
  178. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  179. Koren E, et al. 2022. Nat Commun. 13:4628. PubMed
  180. Bauer T, et al. 2021. Life (Basel). 11:. PubMed
  181. Li P, et al. 2022. EMBO Mol Med. 14:e14511. PubMed
  182. Zuo S, et al. 2021. J Immunother Cancer. 9:. PubMed
  183. Myerson JW, et al. 2021. Nat Nanotechnol. Online ahead of print. PubMed
  184. Jia Q, et al. 2021. Theranostics. 4699:11. PubMed
  185. Paiva-Oliveira E, et al. 2017. Histochem Cell Biol. 10.1007/s00418-017-1556-6. PubMed
  186. Bradley KC, et al. 2019. Cell Rep. 28:245. PubMed
  187. Crooks SD, et al. 2022. Immunohorizons. 6:705. PubMed
  188. Kaur A, et al. 2019. Cancer Discov. 9:64. PubMed
  189. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  190. Zhou G, et al. 2019. FASEB J. 33:11396. PubMed
  191. Shannon JP, et al. 2021. STAR Protoc. 2:100790. PubMed
  192. Yang Y, et al. 2022. Elife. 11:. PubMed
  193. Dey S, et al. 2020. J Immunother Cancer. 8:. PubMed
  194. Zhang Q, et al. 2022. Nat Commun. 13:2406. PubMed
  195. Mizuno T, et al. 2017. Sci Rep. 7:42714. PubMed
  196. Nosho S, et al. 2020. Int J Mol Sci. 21:00. PubMed
  197. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  198. Scur M, et al. 2022. Nat Commun. 13:7272. PubMed
  199. Wang C, et al. 2011. Hepatology. 55:108. PubMed
  200. Sim S, et al. 2016. PLoS One. 11: 0152485. PubMed
  201. Mangum L, et al. 2016. Toxicol Sci. 150: 169 - 177. PubMed
  202. Yamada KJ, et al. 2020. PLoS Pathog. 16:e1008354. PubMed
  203. Limbad C, et al. 2022. iScience. 25:103848. PubMed
  204. Chiang HY, et al. 2022. Nat Commun. 13:874. PubMed
  205. Aguilera M, et al. 2021. Int J Mol Sci. 22:. PubMed
  206. Xi W, et al. 2021. Stem Cell Res Ther. 167:12. PubMed
  207. Shannon JP, et al. 2021. Immunity. 54(2):276-290.e5. PubMed
  208. Dawson CA, et al. 2021. Nature Protocols. 16(4):1907-1935. PubMed
  209. Tu WL, et al. 2018. Am J Pathol. 188:2688. PubMed
  210. Chiche A, et al. 2019. Breast Cancer Res. 21:13. PubMed
  211. Feng J,et al. 2017. Nat Commun. . 10.1038/s41467-017-01056-8. PubMed
  212. Seki T, et al. 2015. J Biochem. 158: 485 - 495. PubMed
  213. Nowlan B, et al. 2019. Haematologica. 105:71. PubMed
  214. Liu D, et al. 2020. Front Pharmacol. 11:204. PubMed
  215. Dion-Albert L, et al. 2022. Nat Commun. 13:164. PubMed
  216. Long JT, et al. 2022. Elife. 11:. PubMed
  217. Zhang Z, et al. 2021. Exp Dermatol. 30:102. PubMed
  218. Perry JL, et al. 2020. ACS Nano. 5.583333333. PubMed
  219. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  220. Penkert RR, et al. 2020. Obesity (Silver Spring). 1631:28. PubMed
  221. Mori A, et al. 2021. Cells. :10. PubMed
  222. Echevarría-Vargas IM, et al. 2018. EMBO Mol Med. 10:e8446. PubMed
  223. Shi R, et al. 2019. J Cancer. 10:367. PubMed
  224. Subramanian K, et al. 2019. Nat Microbiol. 4:62. PubMed
  225. Usmani SM et al. 2019. Cell host & microbe. 25(1):73-86 . PubMed
  226. Zasłona Z, et al. 2017. Am J Physiol Lung Cell Mol Physiol. 312:L855. PubMed
  227. Han Y, et al. 2022. Int J Biol Sci. 18:5653. PubMed
  228. Garcia-Bonilla L, et al. 2014. J Immunol. 193:2531. PubMed
  229. Ding X, et al. 2015. J Immunol. 194:4251. PubMed
  230. Wang L, et al. 2015. Cancer Immunol Res. 3: 1030-1041. PubMed
  231. Mueller A, et al. 2016. Nature. 540:276-279. PubMed
  232. Cai B, et al. 2020. Cell Metabolism. 31(2):406-421.e7.. PubMed
  233. Lu Y, et al. 2020. Immunity. 52:782. PubMed
  234. Saber M, et al. 2021. J Neurosci Res. 99:1136. PubMed
  235. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  236. Murdock BJ, et al. 2021. JCI Insight. 6:. PubMed
  237. Yang Y, et al. 2021. Cell Reports. 34(10):108822. PubMed
  238. Taya M, et al. 2020. Endocr Relat Cancer. 27:261. PubMed
  239. Toyama K, et al. 2018. Arterioscler Thromb Vasc Biol. 38:1392. PubMed
  240. Qiao S, et al. 2019. J Neuroinflammation. 16:4. PubMed
  241. Yousef H, et al. 2019. Nat Med. 25:988. PubMed
  242. Yeo SK, et al. 2020. eLife. 9:e58810.. PubMed
  243. Zhang J, et al. 2022. Biomater Res. 26:44. PubMed
  244. Deng P, et al. 2021. Cell Stem Cell. 28(6):1057-1073.e7. PubMed
  245. Zhang Y, et al. 2020. Cancer Res. 80:3345. PubMed
  246. Carmody C et al. 2019. Endocrinology. 160(5):1205-1222 . PubMed
  247. Fu NY, et al. 2018. Dev Cell. 47:629. PubMed
  248. Hoover AR, et al. 2022. Clin Transl Med. 12:e937. PubMed
  249. Elias S, et al. 2015. PLoS Biol. 13:1002142. PubMed
  250. Nasser H, et al. 2020. Cell Death Discov. 0.29375. PubMed
  251. Sroor HM, et al. 2019. Sci Rep. 9:20217. PubMed
  252. Chen PY, et al. 2019. Nat Metab. 0.675. PubMed
  253. Zheng Y, et al. 2022. J Immunol. 208:501. PubMed
  254. Bagati A, et al. 2020. Cancer Cell. 39(1):54-67.e9. PubMed
  255. Cao Y, et al. 2019. Nat Commun. 10:1280. PubMed
  256. Liu L et al. 2018. Cell stem cell. 23(4):544-556 . PubMed
  257. Cai T, et al. 2022. Nat Commun. 13:2228. PubMed
  258. Zhang T, et al. 2020. JCI Insight. 5:00. PubMed
  259. Porrello A, et al. 2018. Nat Commun. 9:1988. PubMed
  260. Kim KS, et al. 2022. JCI Insight. 7:. PubMed
  261. Liu G, et al. 2022. Theranostics. 12:2248. PubMed
  262. Piirainen S, et al. 2021. Glia. 69:2459. PubMed
  263. Arora S, et al. 2021. Med (N Y). 2:938. PubMed
  264. Li H, et al. 2022. iScience. 25:104481. PubMed
  265. Cayre S, et al. 2020. Development. . PubMed
  266. Endo-Umeda K, et al. 2021. Sci Rep. 11:22595. PubMed
  267. Pal B, et al. 2021. Breast Cancer Res. 23:69. PubMed
  268. Maller O, et al. 2020. Nat Mater. 20:548. PubMed
  269. Saber M, et al. 2020. Eur J Neurosci. 52:2791. PubMed
  270. Ortiz A, et al. 2019. Cancer Cell. 35:33:00. PubMed
  271. Ouadah Y, et al. 2019. Cell. 179:403. PubMed
  272. Piotrowski AF, et al. 2018. Oncoimmunology. 7:e1445951. PubMed
  273. Sarshad AA, et al. 2018. Mol Cell. 71:1040. PubMed
  274. Gopalakrishnapillai A, et al. 2021. Cancers (Basel). 13:. PubMed
  275. Vaas M, et al. 2016. J Cereb Blood Flow Metab. 10.1177/0271678X16676825. PubMed
  276. Wong J, et al. 2016. Sci Signal. 9: ra103. PubMed
  277. Yuan Z, et al. 2016. J Virol. 90: 7728 - 7739. PubMed
  278. Garcia-Bonilla L, et al. 2015. J Neurosci. 35: 14783 - 14793. PubMed
  279. Jiang Y, et al. 2015. MBio. 6: e01426-15. PubMed
  280. Roberts L, et al. 2014. Infect Immun . 82:2504. PubMed
  281. Qu Y, et al. 2020. Cell Reports. 32(1):107873. PubMed
  282. Hu Y, et al. 2021. J Nanobiotechnology. 19:416. PubMed
  283. Kastenschmidt JM, et al. 2021. Cell Rep. 35:108997. PubMed
  284. Jaeger N, et al. 2020. Cell Rep. 33:108331. PubMed
  285. Koh BI, et al. 2020. Nat Commun. 3.143055556. PubMed
  286. Ren D, et al. 2020. Am J Cancer Res. 2851:10. PubMed
  287. Su M, et al. 2018. Immunol Cell Biol. 9:2448. PubMed
  288. Wunderlich CM, et al. 2018. Nat Commun. 9:1646. PubMed
  289. Peltzer N, et al. 2018. Nature. 557:112. PubMed
  290. Liu C, et al. 2022. Nat Commun. 13:1989. PubMed
  291. Saber M, et al. 2021. J Neurotrauma. 38:2862. PubMed
  292. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  293. Okubo A, et al. 2021. Int J Mol Sci. 23:. PubMed
  294. Deets KA, et al. 2021. Elife. 10:. PubMed
  295. Murray CW, et al. 2022. Nat Commun. 13:1090. PubMed
  296. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  297. Zhong J, et al. 2021. Commun Biol. 4:865. PubMed
  298. Xie Z, et al. 2020. Light Sci Appl. 9:161. PubMed
  299. Dai B, et al. 2021. Cell Reports Medicine. 2(8):100381. PubMed
  300. Bravo JI, et al. 2021. STAR Protocols. 2(2):100406. PubMed
  301. Kabir AU, et al. 2018. JCI Insight. 3. PubMed
  302. Quijano-Rubio A, et al. 2022. Nat Biotechnol. Online ahead of print. PubMed
  303. Scheyltjens I, et al. 2022. Nat Protoc. 17:2354. PubMed
  304. Chng S, et al. 2016. Sci Rep. 6: 23820. PubMed
RRID
AB_312976 (BioLegend Cat. No. 103111)
AB_312977 (BioLegend Cat. No. 103112)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine5 anti-mouse CD45 30-F11 FC
PE anti-mouse CD45 30-F11 FC
PE/Cyanine7 anti-mouse CD45 30-F11 FC
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
APC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark Blue™ 515 anti-mouse CD45 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
PE/Fire™ 810 anti-mouse CD45 30-F11 FC
Spark PLUS UV395™ anti-mouse CD45 30-F11 FC
Spark Red™ 718 anti-mouse CD45 30-F11 FC
Spark YG™ 581 anti-mouse CD45 (Flexi-Fluor™) 30-F11 FC
Spark PLUS V475™ anti-mouse CD45 Antibody 30-F11 FC
StarBright UltraViolet 740 anti-mouse CD45 30-F11 FC
Go To Top Version: 2    Revision Date: 05.14.2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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