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APC anti-mouse/human CD44 Antibody APC anti-mouse/human CD44 Antibody

Pricing & Availability
Clone
IM7 (See other available formats)
Regulatory Status
RUO
Other Names
Hermes, Pgp-1, H-CAM, HUTCH-1, ECMR III, gp85, Ly-24
Isotype
Rat IgG2b, κ
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Product Citations
publications
IM7_APC_091907
C57BL/6 mouse splenocytes stained with IM7 APC
  • IM7_APC_091907
    C57BL/6 mouse splenocytes stained with IM7 APC
Compare all formats See APC spectral data
Cat # Size Price Quantity Check Availability Save
103011 25 µg NOK273
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103012 100 µg NOK867
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Description

CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human
Reported Reactivity
Chimpanzee, Baboon, Cynomolgus, Rhesus, Squirrel Monkey, Horse, Cow, Pig, Dog, Cat
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Dexamethasone-induced myeloid leukemia M1 cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The CD44 antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone IM7 has been reported to recognize an epitope common to alloantigens and all isoforms of CD4417,18 that is located between amino acids 145 and 18620. This clone has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F). Additional reported applications (for the relevant formats) include: immunohistochemistry of acetone-fixed frozen sections and formalin-fixed paraffin-embedded sections6,7, complement-mediated cytotoxicity1, immunoprecipitation1,3, in vivo inhibition of DTH4,5, and spatial biology (IBEX)23,24. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103046, 103065 - 103069).

Cross-reactivity to ferret has been reported by a collaborator, but not verified in house.

Application References
  1. Trowbridge IS, et al. 1982. Immunogenetics 15:299. (ICFC, IP, CMCD)
  2. Katoh S, et al. 1994. J. Immunol. 153:3440. (ELISA)
  3. Budd RC, et al. 1987. J. Immunol. 138:3120. (IP)
  4. Camp RL, et al. 1993. J. Exp. Med. 178:497. (Block)
  5. Weiss JM, et al. 1997. J. Cell Biol. 137:1137. (Block)
  6. Frank NY, et al. 2005. Cancer Res. 65:4320. (IHC) PubMed
  7. Cuff CA, et al. 2001. J. Clin. Invest. 108:1031. (IHC)
  8. Lee JW, et al. 2006. Nature Immunol. 8:181.
  9. Zhang N, et al. 2005. J. Immunol. 174:6967. PubMed
  10. Huabiao C, et al. 2005. J. Immunol. 175:591. PubMed
  11. Gui J, et al. 2007. Int. Immunol. 19:1201. PubMed
  12. Wang XY, et al. 2008. Blood 111:2436. PubMed
  13. Kenna TJ, et al. 2008. Blood 111:2091. PubMed
  14. Yamazaki J, et al. 2009. Blood PubMed
  15. Kmieciak M, et al. 2009. J. Transl. Med. 7:89. (FC) PubMed
  16. Chen YW, et al. 2010. Mol. Cancer Ther. 9:2879. PubMed
  17. Zheng Z, et al. 1995. J. Cell. Biol. 130:485.
  18. Wiranowska M, et al. 2010. Int. J. Cancer 127:532.
  19. Hirokawa Y, et al. 2014. Am J Physiol Gastrointerest Liver Physiol. 306:547. PubMed
  20. Sandmaier BM, et al. 1998. Blood 91:3494.
  21. Yang Y, et al. 2015. Hypertension. 65:1047. PubMed
  22. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  23. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  24. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Cignarella F et al. 2018. Cell metabolism. 27(6):1222-1235 . PubMed
  2. Laura C Burzynski et al. 2019. Immunity. 50(4):1033-1042 . PubMed
  3. Valanparambil RM, et al. 2017. PLoS Pathog. 13:e1006647. PubMed
  4. Toubai T, et al. 2017. Blood Adv. 1.095138889. PubMed
  5. Zhou Y, et al. 2021. Methods Mol Biol. 2388:35. PubMed
  6. Xin B, et al. 2022. Hepatology. 76:630. PubMed
  7. Meng J, et al. 2022. Cell Rep. 38:110492. PubMed
  8. Yan Y, et al. 2022. Cell Death Differ. 29:1769. PubMed
  9. Li Y, et al. 2022. J Exp Clin Cancer Res. 41:128. PubMed
  10. Campisi L, et al. 2022. Nature. 606:945. PubMed
  11. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  12. Xia KS, et al. 2023. Bioact Mater. 21:69. PubMed
  13. Kang IH, et al. 2022. iScience. 25:104818. PubMed
  14. Liu M, et al. 2022. Cells. 11: . PubMed
  15. Cagle LA, et al. 2023. Front Physiol. 13:1059686. PubMed
  16. Kasuya T, et al. 2023. Sci Rep. 13:1653. PubMed
  17. Scherer S, et al. 2023. Nat Immunol. 24:501. PubMed
  18. Jiang L, et al. 2021. Nano Today. 36:. PubMed
  19. Kodali S, et al. 2022. J Immunol. 208:1085. PubMed
  20. Bajaj R, et al. 2022. Cell Rep. 40:111429. PubMed
  21. Barsheshet Y, et al. 2022. Int J Mol Sci. 23:. PubMed
  22. Che L, et al. 2023. Foods. 12:. PubMed
  23. Giampaolo S, et al. 2023. iScience. 26:106234. PubMed
  24. van Os BW, et al. 2023. Eur Heart J Open. 3:oead013. PubMed
  25. Liu Y, et al. 2023. Cancers (Basel). 15:. PubMed
  26. Ben-Yaakov H, et al. 2023. Cancers (Basel). 15:. PubMed
  27. Tarafder S, et al. 2023. Bioact Mater. 28:61. PubMed
  28. Tai W, et al. 2023. Nat Commun. 14:2962. PubMed
  29. Yen FC, et al. 2023. Nat Commun. 14:2942. PubMed
  30. Hu Y, et al. 2023. JCI Insight. 8:. PubMed
  31. Pettini E, et al. 2021. Vaccines (Basel). 9:. PubMed
  32. Bergot AS, et al. 2020. J Immunol. 204:1787. PubMed
  33. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  34. Pennock N, et al. 2014. Proc Natl Acad Sci U S A. 111:16472. PubMed
  35. Chen H, et al. 2005. J Immunol. 175:591. PubMed
  36. Viny AD, et al. 2019. Cell Stem Cell. 25:682. PubMed
  37. Shibata K, et al. 2022. Nat Commun. 13:6948. PubMed
  38. Kurosawa M, et al. 2021. Int J Mol Sci. 22:. PubMed
  39. Hamilton JAG, et al. 2021. Aging Cell. 20:e13309. PubMed
  40. Lechuga-Vieco AV, et al. 2020. Sci Adv. 6:eaba5345. PubMed
  41. Gupta SS, et al. 2019. Cell Rep. 29:1862. PubMed
  42. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  43. Liu QZ, et al. 2018. Front Immunol. 1.131944444. PubMed
  44. Nair N, et al. 2020. Curr Protoc Microbiol. 59:e127. PubMed
  45. Christian LS, et al. 2021. Cell Reports. 35(6):109118. PubMed
  46. Limon JJ et al. 2019. Cell host & microbe. 25(3):377-388 . PubMed
  47. Li J, et al. 2022. Int J Biol Sci. 18:2091. PubMed
  48. Menzel L, et al. 2021. Cell Rep. 37:109878. PubMed
  49. Ma C, et al. 2021. Signal Transduct Target Ther. 6:353. PubMed
  50. Plumlee CR, et al. 2020. Cell Host Microbe. 29(1):68-82.e5. PubMed
  51. Yasuoka T, et al. 2016. PLoS One. 11: 0157395. PubMed
  52. Wang Y, et al. 2016. Sci Rep. 6:31881. PubMed
  53. García Nores GD, et al. 2018. Nat Commun. 9:1970. PubMed
  54. Ogawa C et al. 2018. Cell reports. 25(1):19-28 . PubMed
  55. Murphy M, et al. 2017. Eur J Immunol. 47:880. PubMed
  56. Harada Y, et al. 2022. iScience. 25:104021. PubMed
  57. Zhang Q, et al. 2021. Nat Commun. 12:4592. PubMed
  58. Voga M, et al. 2021. Front Vet Sci. 7:610240. PubMed
  59. Inoue D, et al. 2021. Nat Genet. 53:707. PubMed
  60. Flaherty S, Reynolds J 2015. J Vis Exp. 98: 52739. PubMed
  61. Ni F, et al. 2019. Cell Stem Cell. 24:608. PubMed
  62. Sumigray KD et al. 2018. Developmental cell. 45(2):183-197 . PubMed
  63. Liu H, et al. 2022. Nat Commun. 13:3684. PubMed
  64. Geiger R, et al. 2016. Cell. 167:829-842. PubMed
  65. Arandjelovic S, et al. 2010. J Leukoc Biol. 88:737. PubMed
  66. Lo PK, et al. 2018. Elife. 7:e31334. PubMed
  67. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  68. Perry JSA, et al. 2018. Immunity. 48:923. PubMed
  69. Han Y, et al. 2019. Am J Cancer Res. 9:800. PubMed
  70. Yang K, et al. 2022. J Clin Invest. 132:. PubMed
  71. Wang B, et al. 2022. Nat Commun. 13:3821. PubMed
  72. Li J, et al. 2020. Cancer Discov. . PubMed
  73. Pereira JL, et al. 2021. Transl Oncol. 14:101125. PubMed
  74. Maluski M, et al. 2019. J Clin Invest. 129:5108. PubMed
  75. Cheng HW, et al. 2019. Nat Commun. 10:1739. PubMed
  76. Yin Q, et al. 2021. Proc Natl Acad Sci U S A. 118: . PubMed
  77. Skordos I, et al. 2021. STAR Protocols. 2(1):100351. PubMed
  78. Uhde A, et al. 2016. PLoS One. 11: 0161883. PubMed
  79. Kim HR, et al. 2018. Nat Commun. 9:3630. PubMed
  80. Lee CG, et al. 2019. JCI Insight. 4:5. PubMed
  81. Santos CP et al. 2019. Nat Commun. 10(1):4407 . PubMed
  82. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  83. Garhyan J, et al. 2015. Am J Pathol. 185: 1924-1934. PubMed
  84. Dai B, et al. 2012. Mol Ther. 20:1800. PubMed
  85. Place D, et al. 2017. PLoS One. 10.1371/journal.pone.0190384. PubMed
  86. Bankoti R, et al. 2017. Sci Rep. 10.1038/s41598-017-12171-3. PubMed
  87. Florêncio KGD, et al. 2022. Front Immunol. 13:941757. PubMed
  88. Hu Y, et al. 2022. J Nanobiotechnology. 20:417. PubMed
  89. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  90. Kenswil KJG, et al. 2021. Cell Stem Cell. 28(4):653-670.e11. PubMed
  91. Tartey S, et al. 2021. Cancer Research. 81(9):2358-2372. PubMed
  92. Barsoumian HB, et al. 2020. J Immunother Cancer. 8:00. PubMed
  93. Flosbach M, et al. 2020. Cell Reports. 32(4):107957. PubMed
  94. Daly CS, et al. 2018. Oncol Rep. 39:483. PubMed
  95. Kang DW, et al. 2020. J Pathol. 252:304. PubMed
  96. Huang Z, et al. 2021. Nat Commun. 12:145. PubMed
  97. Lee L, et al. 2016. PLoS One. 11:e0167693. PubMed
  98. Naik A, et al. 2015. J Immunol. 194:790. PubMed
  99. Godavarthy PS, et al. 2019. Haematologica. 104(10). PubMed
  100. Clark GC, et al. 2022. Front Oncol. 12:913656. PubMed
  101. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  102. Long H, et al. 2022. Oncol Lett. 23:95. PubMed
  103. Xiao S, et al. 2020. Cell Reports. 32(2):107892. PubMed
  104. Karandikar SH, et al. 2019. JCI Insight. 5. PubMed
  105. Yang BH, et al. 2020. Cell Reports. 27(12):3629-3645.e6.. PubMed
  106. Cañadas I, et al. 2018. Nat Med. 24:1143. PubMed
  107. Akkaya B, et al. 2017. J Immunol Methods. 441:67. PubMed
  108. Guo S, et al. 2021. Sci Rep. 11:23745. PubMed
  109. Liu S, et al. 2022. J Neuroinflammation. 19:35. PubMed
  110. Li J, et al. 2022. Nat Commun. 13:4032. PubMed
  111. Fei W, et al. 2022. Int J Stem Cells. :. PubMed
  112. Wang YT, et al. 2020. Nat Microbiol. 0.397222222. PubMed
  113. Gao Y, et al. 2020. Immunity. 52(6):1007-1021.e8. PubMed
  114. Pastushenko I, et al. 2020. Nature. 589:448. PubMed
  115. Thakur A, et al. 2018. Front Immunol. 2.336805556. PubMed
  116. Jimenez H, et al. 2019. EBioMedicine. 44:209. PubMed
  117. Revathikumar P, et al. 2018. PLoS One. 13:e0193210. PubMed
  118. King R, et al. 2021. Sci Adv. 7:eabj5293. PubMed
  119. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  120. Magness S, et al. 2013. Am J Physiol Gastrointest Liver Physiol. 305:542. PubMed
  121. Jeljeli M, et al. 2021. Front Immunol. 12:670776. PubMed
  122. Tian Q, et al. 2022. Cell Death Dis. 13:71. PubMed
  123. Wang D, et al. 2022. EMBO Rep. 23:e53691. PubMed
  124. Li M, et al. 2021. Br J Pharmacol. 178:2617. PubMed
  125. Younes AI, et al. 2021. Transl Oncol. 14:100983. PubMed
  126. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
  127. Zhang H, et al. 2021. Cell Reports. 35(6):109096. PubMed
  128. Wedekind MF, et al. 2021. iScience. 24(7):102759. PubMed
  129. Zheng B, et al. 2021. Bioact Mater. 6:3879. PubMed
  130. Shissler SC, et al. 2020. Sci Rep. 10:8218. PubMed
  131. Yamazaki M, et al. 2021. Biomedicines. 9:. PubMed
  132. Mairhofer D, et al. 2015. J Invest Dermatol. 135: 2785-93. PubMed
  133. Lau J, et al. 2015. Cancer Res . 75: 4302 - 4311. PubMed
  134. Ma Q, et al. 2022. Vaccines (Basel). 10:. PubMed
  135. Byrne K, et al. 2014. J Immunol. 192:1433. PubMed
  136. Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed
  137. Xu Y, et al. 2016. Nat Commun. 7:12073. PubMed
  138. Kobayashi A, et al. 2011. J Exp Med. 208:2641. PubMed
  139. Hwang WL, et al. 2019. J Hematol Oncol. 12:10. PubMed
  140. Sun Y, et al. 2020. J Immunol. 205:2649. PubMed
  141. Mizuno M, et al. 2021. Cancers (Basel). 13:. PubMed
  142. Norgard RJ, et al. 2021. EMBO Rep. 22:e51872. PubMed
  143. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  144. Parks CA, et al. 2019. Proc Natl Acad Sci U S A. 116:3136. PubMed
  145. Shah D, et al. 2018. Clin Cancer Res. 24:4566. PubMed
  146. Teng F, et al. 2021. Cell Rep. 37:110051. PubMed
  147. Endo-Umeda K, et al. 2021. Sci Rep. 11:22595. PubMed
  148. Weber K, et al. 2008. J Immunol. 180:1442. PubMed
  149. Gejman RS et al. 2018. eLife. 7 pii: e41090. PubMed
  150. Deptuch T, et al. 2022. Sci Rep. 12:13480. PubMed
  151. Hu Y, et al. 2021. J Nanobiotechnology. 19:416. PubMed
  152. Kerdidani D, et al. 2022. J Exp Med. 219:. PubMed
  153. Funk KE, et al. 2021. Aging Cell. 20:e13412. PubMed
  154. Gawish R, et al. 2022. Elife. 11:. PubMed
  155. Lei F, et al. 2012. J Vis Exp. 63: 3986. PubMed
  156. Liu WL, et al. 2019. Nat Commun. 10:3199. PubMed
  157. Cao Y, et al. 2022. Small. 18:e2203466. PubMed
  158. Plaza-Sirvent C, et al. 2021. Front Immunol. 12:705436. PubMed
  159. Wang W, et al. 2022. Oxid Med Cell Longev. 2022:8172866. PubMed
  160. Swanson WB, et al. 2021. Biomaterials. 272:120769. PubMed
  161. Avgustinova A, et al. 2021. Cell Stem Cell. . PubMed
  162. Guo S, et al. 2021. Frontiers in Immunology. 11:614667. PubMed
  163. Cignarella F et al. 2018. Cell metabolism. 27(6):1222-1235 . PubMed
  164. Laura C Burzynski et al. 2019. Immunity. 50(4):1033-1042 . PubMed
  165. Valanparambil RM, et al. 2017. PLoS Pathog. 13:e1006647. PubMed
  166. Toubai T, et al. 2017. Blood Adv. 1.095138889. PubMed
  167. Zhou Y, et al. 2021. Methods Mol Biol. 2388:35. PubMed
  168. Xin B, et al. 2022. Hepatology. 76:630. PubMed
  169. Meng J, et al. 2022. Cell Rep. 38:110492. PubMed
  170. Yan Y, et al. 2022. Cell Death Differ. 29:1769. PubMed
  171. Li Y, et al. 2022. J Exp Clin Cancer Res. 41:128. PubMed
  172. Campisi L, et al. 2022. Nature. 606:945. PubMed
  173. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  174. Xia KS, et al. 2023. Bioact Mater. 21:69. PubMed
  175. Kang IH, et al. 2022. iScience. 25:104818. PubMed
  176. Liu M, et al. 2022. Cells. 11: . PubMed
  177. Cagle LA, et al. 2023. Front Physiol. 13:1059686. PubMed
  178. Kasuya T, et al. 2023. Sci Rep. 13:1653. PubMed
  179. Scherer S, et al. 2023. Nat Immunol. 24:501. PubMed
  180. Jiang L, et al. 2021. Nano Today. 36:. PubMed
  181. Kodali S, et al. 2022. J Immunol. 208:1085. PubMed
  182. Bajaj R, et al. 2022. Cell Rep. 40:111429. PubMed
  183. Barsheshet Y, et al. 2022. Int J Mol Sci. 23:. PubMed
  184. Che L, et al. 2023. Foods. 12:. PubMed
  185. Giampaolo S, et al. 2023. iScience. 26:106234. PubMed
  186. van Os BW, et al. 2023. Eur Heart J Open. 3:oead013. PubMed
  187. Liu Y, et al. 2023. Cancers (Basel). 15:. PubMed
  188. Ben-Yaakov H, et al. 2023. Cancers (Basel). 15:. PubMed
  189. Tarafder S, et al. 2023. Bioact Mater. 28:61. PubMed
  190. Tai W, et al. 2023. Nat Commun. 14:2962. PubMed
  191. Yen FC, et al. 2023. Nat Commun. 14:2942. PubMed
  192. Hu Y, et al. 2023. JCI Insight. 8:. PubMed
  193. Pettini E, et al. 2021. Vaccines (Basel). 9:. PubMed
  194. Bergot AS, et al. 2020. J Immunol. 204:1787. PubMed
  195. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  196. Pennock N, et al. 2014. Proc Natl Acad Sci U S A. 111:16472. PubMed
  197. Chen H, et al. 2005. J Immunol. 175:591. PubMed
  198. Viny AD, et al. 2019. Cell Stem Cell. 25:682. PubMed
  199. Shibata K, et al. 2022. Nat Commun. 13:6948. PubMed
  200. Kurosawa M, et al. 2021. Int J Mol Sci. 22:. PubMed
  201. Hamilton JAG, et al. 2021. Aging Cell. 20:e13309. PubMed
  202. Lechuga-Vieco AV, et al. 2020. Sci Adv. 6:eaba5345. PubMed
  203. Gupta SS, et al. 2019. Cell Rep. 29:1862. PubMed
  204. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  205. Liu QZ, et al. 2018. Front Immunol. 1.131944444. PubMed
  206. Nair N, et al. 2020. Curr Protoc Microbiol. 59:e127. PubMed
  207. Christian LS, et al. 2021. Cell Reports. 35(6):109118. PubMed
  208. Limon JJ et al. 2019. Cell host & microbe. 25(3):377-388 . PubMed
  209. Li J, et al. 2022. Int J Biol Sci. 18:2091. PubMed
  210. Menzel L, et al. 2021. Cell Rep. 37:109878. PubMed
  211. Ma C, et al. 2021. Signal Transduct Target Ther. 6:353. PubMed
  212. Plumlee CR, et al. 2020. Cell Host Microbe. 29(1):68-82.e5. PubMed
  213. Yasuoka T, et al. 2016. PLoS One. 11: 0157395. PubMed
  214. Wang Y, et al. 2016. Sci Rep. 6:31881. PubMed
  215. García Nores GD, et al. 2018. Nat Commun. 9:1970. PubMed
  216. Ogawa C et al. 2018. Cell reports. 25(1):19-28 . PubMed
  217. Murphy M, et al. 2017. Eur J Immunol. 47:880. PubMed
  218. Harada Y, et al. 2022. iScience. 25:104021. PubMed
  219. Zhang Q, et al. 2021. Nat Commun. 12:4592. PubMed
  220. Voga M, et al. 2021. Front Vet Sci. 7:610240. PubMed
  221. Inoue D, et al. 2021. Nat Genet. 53:707. PubMed
  222. Flaherty S, Reynolds J 2015. J Vis Exp. 98: 52739. PubMed
  223. Ni F, et al. 2019. Cell Stem Cell. 24:608. PubMed
  224. Sumigray KD et al. 2018. Developmental cell. 45(2):183-197 . PubMed
  225. Liu H, et al. 2022. Nat Commun. 13:3684. PubMed
  226. Geiger R, et al. 2016. Cell. 167:829-842. PubMed
  227. Arandjelovic S, et al. 2010. J Leukoc Biol. 88:737. PubMed
  228. Lo PK, et al. 2018. Elife. 7:e31334. PubMed
  229. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  230. Perry JSA, et al. 2018. Immunity. 48:923. PubMed
  231. Han Y, et al. 2019. Am J Cancer Res. 9:800. PubMed
  232. Yang K, et al. 2022. J Clin Invest. 132:. PubMed
  233. Wang B, et al. 2022. Nat Commun. 13:3821. PubMed
  234. Li J, et al. 2020. Cancer Discov. . PubMed
  235. Pereira JL, et al. 2021. Transl Oncol. 14:101125. PubMed
  236. Maluski M, et al. 2019. J Clin Invest. 129:5108. PubMed
  237. Cheng HW, et al. 2019. Nat Commun. 10:1739. PubMed
  238. Yin Q, et al. 2021. Proc Natl Acad Sci U S A. 118: . PubMed
  239. Skordos I, et al. 2021. STAR Protocols. 2(1):100351. PubMed
  240. Uhde A, et al. 2016. PLoS One. 11: 0161883. PubMed
  241. Kim HR, et al. 2018. Nat Commun. 9:3630. PubMed
  242. Lee CG, et al. 2019. JCI Insight. 4:5. PubMed
  243. Santos CP et al. 2019. Nat Commun. 10(1):4407 . PubMed
  244. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  245. Garhyan J, et al. 2015. Am J Pathol. 185: 1924-1934. PubMed
  246. Dai B, et al. 2012. Mol Ther. 20:1800. PubMed
  247. Place D, et al. 2017. PLoS One. 10.1371/journal.pone.0190384. PubMed
  248. Bankoti R, et al. 2017. Sci Rep. 10.1038/s41598-017-12171-3. PubMed
  249. Florêncio KGD, et al. 2022. Front Immunol. 13:941757. PubMed
  250. Hu Y, et al. 2022. J Nanobiotechnology. 20:417. PubMed
  251. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  252. Kenswil KJG, et al. 2021. Cell Stem Cell. 28(4):653-670.e11. PubMed
  253. Tartey S, et al. 2021. Cancer Research. 81(9):2358-2372. PubMed
  254. Barsoumian HB, et al. 2020. J Immunother Cancer. 8:00. PubMed
  255. Flosbach M, et al. 2020. Cell Reports. 32(4):107957. PubMed
  256. Daly CS, et al. 2018. Oncol Rep. 39:483. PubMed
  257. Kang DW, et al. 2020. J Pathol. 252:304. PubMed
  258. Huang Z, et al. 2021. Nat Commun. 12:145. PubMed
  259. Lee L, et al. 2016. PLoS One. 11:e0167693. PubMed
  260. Naik A, et al. 2015. J Immunol. 194:790. PubMed
  261. Godavarthy PS, et al. 2019. Haematologica. 104(10). PubMed
  262. Clark GC, et al. 2022. Front Oncol. 12:913656. PubMed
  263. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  264. Long H, et al. 2022. Oncol Lett. 23:95. PubMed
  265. Xiao S, et al. 2020. Cell Reports. 32(2):107892. PubMed
  266. Karandikar SH, et al. 2019. JCI Insight. 5. PubMed
  267. Yang BH, et al. 2020. Cell Reports. 27(12):3629-3645.e6.. PubMed
  268. Cañadas I, et al. 2018. Nat Med. 24:1143. PubMed
  269. Akkaya B, et al. 2017. J Immunol Methods. 441:67. PubMed
  270. Guo S, et al. 2021. Sci Rep. 11:23745. PubMed
  271. Liu S, et al. 2022. J Neuroinflammation. 19:35. PubMed
  272. Li J, et al. 2022. Nat Commun. 13:4032. PubMed
  273. Fei W, et al. 2022. Int J Stem Cells. :. PubMed
  274. Wang YT, et al. 2020. Nat Microbiol. 0.397222222. PubMed
  275. Gao Y, et al. 2020. Immunity. 52(6):1007-1021.e8. PubMed
  276. Pastushenko I, et al. 2020. Nature. 589:448. PubMed
  277. Thakur A, et al. 2018. Front Immunol. 2.336805556. PubMed
  278. Jimenez H, et al. 2019. EBioMedicine. 44:209. PubMed
  279. Revathikumar P, et al. 2018. PLoS One. 13:e0193210. PubMed
  280. King R, et al. 2021. Sci Adv. 7:eabj5293. PubMed
  281. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  282. Magness S, et al. 2013. Am J Physiol Gastrointest Liver Physiol. 305:542. PubMed
  283. Jeljeli M, et al. 2021. Front Immunol. 12:670776. PubMed
  284. Tian Q, et al. 2022. Cell Death Dis. 13:71. PubMed
  285. Wang D, et al. 2022. EMBO Rep. 23:e53691. PubMed
  286. Li M, et al. 2021. Br J Pharmacol. 178:2617. PubMed
  287. Younes AI, et al. 2021. Transl Oncol. 14:100983. PubMed
  288. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
  289. Zhang H, et al. 2021. Cell Reports. 35(6):109096. PubMed
  290. Wedekind MF, et al. 2021. iScience. 24(7):102759. PubMed
  291. Zheng B, et al. 2021. Bioact Mater. 6:3879. PubMed
  292. Shissler SC, et al. 2020. Sci Rep. 10:8218. PubMed
  293. Yamazaki M, et al. 2021. Biomedicines. 9:. PubMed
  294. Mairhofer D, et al. 2015. J Invest Dermatol. 135: 2785-93. PubMed
  295. Lau J, et al. 2015. Cancer Res . 75: 4302 - 4311. PubMed
  296. Ma Q, et al. 2022. Vaccines (Basel). 10:. PubMed
  297. Byrne K, et al. 2014. J Immunol. 192:1433. PubMed
  298. Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed
  299. Xu Y, et al. 2016. Nat Commun. 7:12073. PubMed
  300. Kobayashi A, et al. 2011. J Exp Med. 208:2641. PubMed
  301. Hwang WL, et al. 2019. J Hematol Oncol. 12:10. PubMed
  302. Sun Y, et al. 2020. J Immunol. 205:2649. PubMed
  303. Mizuno M, et al. 2021. Cancers (Basel). 13:. PubMed
  304. Norgard RJ, et al. 2021. EMBO Rep. 22:e51872. PubMed
  305. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  306. Parks CA, et al. 2019. Proc Natl Acad Sci U S A. 116:3136. PubMed
  307. Shah D, et al. 2018. Clin Cancer Res. 24:4566. PubMed
  308. Teng F, et al. 2021. Cell Rep. 37:110051. PubMed
  309. Endo-Umeda K, et al. 2021. Sci Rep. 11:22595. PubMed
  310. Weber K, et al. 2008. J Immunol. 180:1442. PubMed
  311. Gejman RS et al. 2018. eLife. 7 pii: e41090. PubMed
  312. Deptuch T, et al. 2022. Sci Rep. 12:13480. PubMed
  313. Hu Y, et al. 2021. J Nanobiotechnology. 19:416. PubMed
  314. Kerdidani D, et al. 2022. J Exp Med. 219:. PubMed
  315. Funk KE, et al. 2021. Aging Cell. 20:e13412. PubMed
  316. Gawish R, et al. 2022. Elife. 11:. PubMed
  317. Lei F, et al. 2012. J Vis Exp. 63: 3986. PubMed
  318. Liu WL, et al. 2019. Nat Commun. 10:3199. PubMed
  319. Cao Y, et al. 2022. Small. 18:e2203466. PubMed
  320. Plaza-Sirvent C, et al. 2021. Front Immunol. 12:705436. PubMed
  321. Wang W, et al. 2022. Oxid Med Cell Longev. 2022:8172866. PubMed
  322. Swanson WB, et al. 2021. Biomaterials. 272:120769. PubMed
  323. Avgustinova A, et al. 2021. Cell Stem Cell. . PubMed
  324. Guo S, et al. 2021. Frontiers in Immunology. 11:614667. PubMed
RRID
AB_312962 (BioLegend Cat. No. 103011)
AB_312963 (BioLegend Cat. No. 103012)

Antigen Details

Structure
Variable splicing of CD44 gene generates many CD44 isoforms, 80-95 kD
Distribution

All leukocytes, epithelial cells, endothelial cells, hepatocytes, mesenchymal cells

Function
Leukocyte attachment and rolling on endothelial cells, stromal cells and ECM
Ligand/Receptor
Hyaluronan, MIP-1β, fibronectin, collagen
Cell Type
B cells, Endothelial cells, Epithelial cells, Leukocytes, Mesenchymal cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Immunology, Stem Cells
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Haynes BF, et al. 1991. Cancer Cells 3:347.
3. Goldstein LA, et al. 1989. Cell 56:1063.
4. Mikecz K, et al. 1995. Nat. Med. 1:558.
5. Hegde V, et al. 2008. J. Leukocyte Biol. 84:134.
6. Liu T, et al. 2009. Biol. Direct 4:40.

Gene ID
12505 View all products for this Gene ID 960 View all products for this Gene ID
UniProt
View information about CD44 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD44 Reagents Request Custom Conjugation
Description Clone Applications
PE/Dazzle™ 594 anti-mouse/human CD44 IM7 FC
Brilliant Violet 711™ anti-mouse/human CD44 IM7 FC
APC/Fire™ 750 anti-mouse/human CD44 IM7 FC
TotalSeq™-A0073 anti-mouse/human CD44 IM7 PG
TotalSeq™-C0073 anti-mouse/human CD44 IM7 PG
TotalSeq™-B0073 anti-mouse/human CD44 IM7 PG
Spark YG™ 570 anti-mouse/human CD44 IM7 FC,IHC-P
Spark YG™ 593 anti-mouse/human CD44 IM7 FC
TotalSeq™-D0073 anti-mouse/human CD44 IM7 PG
PE anti-mouse/human CD44 IM7 FC
Brilliant Violet 750™ anti-mouse/human CD44 IM7 FC
PerCP/Fire™ 806 anti-mouse/human CD44 IM7 FC
Spark Red™ 718 anti-mouse/human CD44 IM7 FC
PE/Fire™ 810 anti-mouse/human CD44 IM7 FC
Spark Blue™ 550 anti-mouse/human CD44 (Flexi-Fluor™) IM7 FC
Spark YG™ 581 anti-mouse/human CD44 (Flexi-Fluor™) IM7 FC
Spark NIR™ 685 anti-mouse/human CD44 (Flexi-Fluor™) Antibody IM7 FC
Spark UV™ 387 anti-mouse/human CD44 (Flexi-Fluor™) IM7 FC
StarBright UltraViolet 795 anti-mouse/human CD44 IM7 FC
Alexa Fluor® 488 anti-mouse/human CD44 IM7 FC,ICC,IHC-P,SB
Alexa Fluor® 647 anti-mouse/human CD44 IM7 FC,ICC,SB
Pacific Blue™ anti-mouse/human CD44 IM7 FC
APC anti-mouse/human CD44 IM7 FC
Biotin anti-mouse/human CD44 IM7 FC,ICC,IHC-P
FITC anti-mouse/human CD44 IM7 FC,ICC,IHC-P
PE/Cyanine5 anti-mouse/human CD44 IM7 FC
Purified anti-mouse/human CD44 IM7 FC,IHC-F,CyTOF®,ELISA,ICC,IHC-P,IP,CMCD,Stim
Alexa Fluor® 700 anti-mouse/human CD44 IM7 FC,SB
PE/Cyanine7 anti-mouse/human CD44 IM7 FC
APC/Cyanine7 anti-mouse/human CD44 IM7 FC
PerCP/Cyanine5.5 anti-mouse/human CD44 IM7 FC
PerCP anti-mouse/human CD44 IM7 FC
Brilliant Violet 421™ anti-mouse/human CD44 IM7 FC,ICC,IHC-P
Brilliant Violet 570™ anti-mouse/human CD44 IM7 FC
Brilliant Violet 785™ anti-mouse/human CD44 IM7 FC
Brilliant Violet 510™ anti-mouse/human CD44 IM7 FC
Ultra-LEAF™ Purified anti-mouse/human CD44 IM7 FC,CyTOF®,ELISA,IHC,IP,CMCD,Stim
Brilliant Violet 605™ anti-mouse/human CD44 IM7 FC
Brilliant Violet 650™ anti-mouse/human CD44 IM7 FC
Purified anti-mouse/human CD44 (Maxpar® Ready) IM7 FC,CyTOF®
Alexa Fluor® 594 anti-mouse/human CD44 IM7 ICC,FC,IHC-P,SB
Go To Top Version: 2    Revision Date: 09.11.2014

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Pricing & Availability
Clone
IM7 (See other available formats)
Regulatory Status
RUO
Other Names
Hermes, Pgp-1, H-CAM, HUTCH-1, ECMR III, gp85, Ly-24
Isotype
Rat IgG2b, κ
Ave. Rating
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Product Citations
publications
IM7_APC_091907
C57BL/6 mouse splenocytes stained with IM7 APC
  • IM7_APC_091907
    C57BL/6 mouse splenocytes stained with IM7 APC
Compare all formats See APC spectral data
Cat # Size Price Quantity Check Availability Save
103011 25 µg NOK273
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103012 100 µg NOK867
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Description

CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human
Reported Reactivity
Chimpanzee, Baboon, Cynomolgus, Rhesus, Squirrel Monkey, Horse, Cow, Pig, Dog, Cat
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Dexamethasone-induced myeloid leukemia M1 cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The CD44 antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone IM7 has been reported to recognize an epitope common to alloantigens and all isoforms of CD4417,18 that is located between amino acids 145 and 18620. This clone has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F). Additional reported applications (for the relevant formats) include: immunohistochemistry of acetone-fixed frozen sections and formalin-fixed paraffin-embedded sections6,7, complement-mediated cytotoxicity1, immunoprecipitation1,3, in vivo inhibition of DTH4,5, and spatial biology (IBEX)23,24. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103046, 103065 - 103069).

Cross-reactivity to ferret has been reported by a collaborator, but not verified in house.

Application References
  1. Trowbridge IS, et al. 1982. Immunogenetics 15:299. (ICFC, IP, CMCD)
  2. Katoh S, et al. 1994. J. Immunol. 153:3440. (ELISA)
  3. Budd RC, et al. 1987. J. Immunol. 138:3120. (IP)
  4. Camp RL, et al. 1993. J. Exp. Med. 178:497. (Block)
  5. Weiss JM, et al. 1997. J. Cell Biol. 137:1137. (Block)
  6. Frank NY, et al. 2005. Cancer Res. 65:4320. (IHC) PubMed
  7. Cuff CA, et al. 2001. J. Clin. Invest. 108:1031. (IHC)
  8. Lee JW, et al. 2006. Nature Immunol. 8:181.
  9. Zhang N, et al. 2005. J. Immunol. 174:6967. PubMed
  10. Huabiao C, et al. 2005. J. Immunol. 175:591. PubMed
  11. Gui J, et al. 2007. Int. Immunol. 19:1201. PubMed
  12. Wang XY, et al. 2008. Blood 111:2436. PubMed
  13. Kenna TJ, et al. 2008. Blood 111:2091. PubMed
  14. Yamazaki J, et al. 2009. Blood PubMed
  15. Kmieciak M, et al. 2009. J. Transl. Med. 7:89. (FC) PubMed
  16. Chen YW, et al. 2010. Mol. Cancer Ther. 9:2879. PubMed
  17. Zheng Z, et al. 1995. J. Cell. Biol. 130:485.
  18. Wiranowska M, et al. 2010. Int. J. Cancer 127:532.
  19. Hirokawa Y, et al. 2014. Am J Physiol Gastrointerest Liver Physiol. 306:547. PubMed
  20. Sandmaier BM, et al. 1998. Blood 91:3494.
  21. Yang Y, et al. 2015. Hypertension. 65:1047. PubMed
  22. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
  23. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  24. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Cignarella F et al. 2018. Cell metabolism. 27(6):1222-1235 . PubMed
  2. Laura C Burzynski et al. 2019. Immunity. 50(4):1033-1042 . PubMed
  3. Valanparambil RM, et al. 2017. PLoS Pathog. 13:e1006647. PubMed
  4. Toubai T, et al. 2017. Blood Adv. 1.095138889. PubMed
  5. Zhou Y, et al. 2021. Methods Mol Biol. 2388:35. PubMed
  6. Xin B, et al. 2022. Hepatology. 76:630. PubMed
  7. Meng J, et al. 2022. Cell Rep. 38:110492. PubMed
  8. Yan Y, et al. 2022. Cell Death Differ. 29:1769. PubMed
  9. Li Y, et al. 2022. J Exp Clin Cancer Res. 41:128. PubMed
  10. Campisi L, et al. 2022. Nature. 606:945. PubMed
  11. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  12. Xia KS, et al. 2023. Bioact Mater. 21:69. PubMed
  13. Kang IH, et al. 2022. iScience. 25:104818. PubMed
  14. Liu M, et al. 2022. Cells. 11: . PubMed
  15. Cagle LA, et al. 2023. Front Physiol. 13:1059686. PubMed
  16. Kasuya T, et al. 2023. Sci Rep. 13:1653. PubMed
  17. Scherer S, et al. 2023. Nat Immunol. 24:501. PubMed
  18. Jiang L, et al. 2021. Nano Today. 36:. PubMed
  19. Kodali S, et al. 2022. J Immunol. 208:1085. PubMed
  20. Bajaj R, et al. 2022. Cell Rep. 40:111429. PubMed
  21. Barsheshet Y, et al. 2022. Int J Mol Sci. 23:. PubMed
  22. Che L, et al. 2023. Foods. 12:. PubMed
  23. Giampaolo S, et al. 2023. iScience. 26:106234. PubMed
  24. van Os BW, et al. 2023. Eur Heart J Open. 3:oead013. PubMed
  25. Liu Y, et al. 2023. Cancers (Basel). 15:. PubMed
  26. Ben-Yaakov H, et al. 2023. Cancers (Basel). 15:. PubMed
  27. Tarafder S, et al. 2023. Bioact Mater. 28:61. PubMed
  28. Tai W, et al. 2023. Nat Commun. 14:2962. PubMed
  29. Yen FC, et al. 2023. Nat Commun. 14:2942. PubMed
  30. Hu Y, et al. 2023. JCI Insight. 8:. PubMed
  31. Pettini E, et al. 2021. Vaccines (Basel). 9:. PubMed
  32. Bergot AS, et al. 2020. J Immunol. 204:1787. PubMed
  33. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  34. Pennock N, et al. 2014. Proc Natl Acad Sci U S A. 111:16472. PubMed
  35. Chen H, et al. 2005. J Immunol. 175:591. PubMed
  36. Viny AD, et al. 2019. Cell Stem Cell. 25:682. PubMed
  37. Shibata K, et al. 2022. Nat Commun. 13:6948. PubMed
  38. Kurosawa M, et al. 2021. Int J Mol Sci. 22:. PubMed
  39. Hamilton JAG, et al. 2021. Aging Cell. 20:e13309. PubMed
  40. Lechuga-Vieco AV, et al. 2020. Sci Adv. 6:eaba5345. PubMed
  41. Gupta SS, et al. 2019. Cell Rep. 29:1862. PubMed
  42. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  43. Liu QZ, et al. 2018. Front Immunol. 1.131944444. PubMed
  44. Nair N, et al. 2020. Curr Protoc Microbiol. 59:e127. PubMed
  45. Christian LS, et al. 2021. Cell Reports. 35(6):109118. PubMed
  46. Limon JJ et al. 2019. Cell host & microbe. 25(3):377-388 . PubMed
  47. Li J, et al. 2022. Int J Biol Sci. 18:2091. PubMed
  48. Menzel L, et al. 2021. Cell Rep. 37:109878. PubMed
  49. Ma C, et al. 2021. Signal Transduct Target Ther. 6:353. PubMed
  50. Plumlee CR, et al. 2020. Cell Host Microbe. 29(1):68-82.e5. PubMed
  51. Yasuoka T, et al. 2016. PLoS One. 11: 0157395. PubMed
  52. Wang Y, et al. 2016. Sci Rep. 6:31881. PubMed
  53. García Nores GD, et al. 2018. Nat Commun. 9:1970. PubMed
  54. Ogawa C et al. 2018. Cell reports. 25(1):19-28 . PubMed
  55. Murphy M, et al. 2017. Eur J Immunol. 47:880. PubMed
  56. Harada Y, et al. 2022. iScience. 25:104021. PubMed
  57. Zhang Q, et al. 2021. Nat Commun. 12:4592. PubMed
  58. Voga M, et al. 2021. Front Vet Sci. 7:610240. PubMed
  59. Inoue D, et al. 2021. Nat Genet. 53:707. PubMed
  60. Flaherty S, Reynolds J 2015. J Vis Exp. 98: 52739. PubMed
  61. Ni F, et al. 2019. Cell Stem Cell. 24:608. PubMed
  62. Sumigray KD et al. 2018. Developmental cell. 45(2):183-197 . PubMed
  63. Liu H, et al. 2022. Nat Commun. 13:3684. PubMed
  64. Geiger R, et al. 2016. Cell. 167:829-842. PubMed
  65. Arandjelovic S, et al. 2010. J Leukoc Biol. 88:737. PubMed
  66. Lo PK, et al. 2018. Elife. 7:e31334. PubMed
  67. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  68. Perry JSA, et al. 2018. Immunity. 48:923. PubMed
  69. Han Y, et al. 2019. Am J Cancer Res. 9:800. PubMed
  70. Yang K, et al. 2022. J Clin Invest. 132:. PubMed
  71. Wang B, et al. 2022. Nat Commun. 13:3821. PubMed
  72. Li J, et al. 2020. Cancer Discov. . PubMed
  73. Pereira JL, et al. 2021. Transl Oncol. 14:101125. PubMed
  74. Maluski M, et al. 2019. J Clin Invest. 129:5108. PubMed
  75. Cheng HW, et al. 2019. Nat Commun. 10:1739. PubMed
  76. Yin Q, et al. 2021. Proc Natl Acad Sci U S A. 118: . PubMed
  77. Skordos I, et al. 2021. STAR Protocols. 2(1):100351. PubMed
  78. Uhde A, et al. 2016. PLoS One. 11: 0161883. PubMed
  79. Kim HR, et al. 2018. Nat Commun. 9:3630. PubMed
  80. Lee CG, et al. 2019. JCI Insight. 4:5. PubMed
  81. Santos CP et al. 2019. Nat Commun. 10(1):4407 . PubMed
  82. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  83. Garhyan J, et al. 2015. Am J Pathol. 185: 1924-1934. PubMed
  84. Dai B, et al. 2012. Mol Ther. 20:1800. PubMed
  85. Place D, et al. 2017. PLoS One. 10.1371/journal.pone.0190384. PubMed
  86. Bankoti R, et al. 2017. Sci Rep. 10.1038/s41598-017-12171-3. PubMed
  87. Florêncio KGD, et al. 2022. Front Immunol. 13:941757. PubMed
  88. Hu Y, et al. 2022. J Nanobiotechnology. 20:417. PubMed
  89. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  90. Kenswil KJG, et al. 2021. Cell Stem Cell. 28(4):653-670.e11. PubMed
  91. Tartey S, et al. 2021. Cancer Research. 81(9):2358-2372. PubMed
  92. Barsoumian HB, et al. 2020. J Immunother Cancer. 8:00. PubMed
  93. Flosbach M, et al. 2020. Cell Reports. 32(4):107957. PubMed
  94. Daly CS, et al. 2018. Oncol Rep. 39:483. PubMed
  95. Kang DW, et al. 2020. J Pathol. 252:304. PubMed
  96. Huang Z, et al. 2021. Nat Commun. 12:145. PubMed
  97. Lee L, et al. 2016. PLoS One. 11:e0167693. PubMed
  98. Naik A, et al. 2015. J Immunol. 194:790. PubMed
  99. Godavarthy PS, et al. 2019. Haematologica. 104(10). PubMed
  100. Clark GC, et al. 2022. Front Oncol. 12:913656. PubMed
  101. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  102. Long H, et al. 2022. Oncol Lett. 23:95. PubMed
  103. Xiao S, et al. 2020. Cell Reports. 32(2):107892. PubMed
  104. Karandikar SH, et al. 2019. JCI Insight. 5. PubMed
  105. Yang BH, et al. 2020. Cell Reports. 27(12):3629-3645.e6.. PubMed
  106. Cañadas I, et al. 2018. Nat Med. 24:1143. PubMed
  107. Akkaya B, et al. 2017. J Immunol Methods. 441:67. PubMed
  108. Guo S, et al. 2021. Sci Rep. 11:23745. PubMed
  109. Liu S, et al. 2022. J Neuroinflammation. 19:35. PubMed
  110. Li J, et al. 2022. Nat Commun. 13:4032. PubMed
  111. Fei W, et al. 2022. Int J Stem Cells. :. PubMed
  112. Wang YT, et al. 2020. Nat Microbiol. 0.397222222. PubMed
  113. Gao Y, et al. 2020. Immunity. 52(6):1007-1021.e8. PubMed
  114. Pastushenko I, et al. 2020. Nature. 589:448. PubMed
  115. Thakur A, et al. 2018. Front Immunol. 2.336805556. PubMed
  116. Jimenez H, et al. 2019. EBioMedicine. 44:209. PubMed
  117. Revathikumar P, et al. 2018. PLoS One. 13:e0193210. PubMed
  118. King R, et al. 2021. Sci Adv. 7:eabj5293. PubMed
  119. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  120. Magness S, et al. 2013. Am J Physiol Gastrointest Liver Physiol. 305:542. PubMed
  121. Jeljeli M, et al. 2021. Front Immunol. 12:670776. PubMed
  122. Tian Q, et al. 2022. Cell Death Dis. 13:71. PubMed
  123. Wang D, et al. 2022. EMBO Rep. 23:e53691. PubMed
  124. Li M, et al. 2021. Br J Pharmacol. 178:2617. PubMed
  125. Younes AI, et al. 2021. Transl Oncol. 14:100983. PubMed
  126. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
  127. Zhang H, et al. 2021. Cell Reports. 35(6):109096. PubMed
  128. Wedekind MF, et al. 2021. iScience. 24(7):102759. PubMed
  129. Zheng B, et al. 2021. Bioact Mater. 6:3879. PubMed
  130. Shissler SC, et al. 2020. Sci Rep. 10:8218. PubMed
  131. Yamazaki M, et al. 2021. Biomedicines. 9:. PubMed
  132. Mairhofer D, et al. 2015. J Invest Dermatol. 135: 2785-93. PubMed
  133. Lau J, et al. 2015. Cancer Res . 75: 4302 - 4311. PubMed
  134. Ma Q, et al. 2022. Vaccines (Basel). 10:. PubMed
  135. Byrne K, et al. 2014. J Immunol. 192:1433. PubMed
  136. Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed
  137. Xu Y, et al. 2016. Nat Commun. 7:12073. PubMed
  138. Kobayashi A, et al. 2011. J Exp Med. 208:2641. PubMed
  139. Hwang WL, et al. 2019. J Hematol Oncol. 12:10. PubMed
  140. Sun Y, et al. 2020. J Immunol. 205:2649. PubMed
  141. Mizuno M, et al. 2021. Cancers (Basel). 13:. PubMed
  142. Norgard RJ, et al. 2021. EMBO Rep. 22:e51872. PubMed
  143. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  144. Parks CA, et al. 2019. Proc Natl Acad Sci U S A. 116:3136. PubMed
  145. Shah D, et al. 2018. Clin Cancer Res. 24:4566. PubMed
  146. Teng F, et al. 2021. Cell Rep. 37:110051. PubMed
  147. Endo-Umeda K, et al. 2021. Sci Rep. 11:22595. PubMed
  148. Weber K, et al. 2008. J Immunol. 180:1442. PubMed
  149. Gejman RS et al. 2018. eLife. 7 pii: e41090. PubMed
  150. Deptuch T, et al. 2022. Sci Rep. 12:13480. PubMed
  151. Hu Y, et al. 2021. J Nanobiotechnology. 19:416. PubMed
  152. Kerdidani D, et al. 2022. J Exp Med. 219:. PubMed
  153. Funk KE, et al. 2021. Aging Cell. 20:e13412. PubMed
  154. Gawish R, et al. 2022. Elife. 11:. PubMed
  155. Lei F, et al. 2012. J Vis Exp. 63: 3986. PubMed
  156. Liu WL, et al. 2019. Nat Commun. 10:3199. PubMed
  157. Cao Y, et al. 2022. Small. 18:e2203466. PubMed
  158. Plaza-Sirvent C, et al. 2021. Front Immunol. 12:705436. PubMed
  159. Wang W, et al. 2022. Oxid Med Cell Longev. 2022:8172866. PubMed
  160. Swanson WB, et al. 2021. Biomaterials. 272:120769. PubMed
  161. Avgustinova A, et al. 2021. Cell Stem Cell. . PubMed
  162. Guo S, et al. 2021. Frontiers in Immunology. 11:614667. PubMed
  163. Cignarella F et al. 2018. Cell metabolism. 27(6):1222-1235 . PubMed
  164. Laura C Burzynski et al. 2019. Immunity. 50(4):1033-1042 . PubMed
  165. Valanparambil RM, et al. 2017. PLoS Pathog. 13:e1006647. PubMed
  166. Toubai T, et al. 2017. Blood Adv. 1.095138889. PubMed
  167. Zhou Y, et al. 2021. Methods Mol Biol. 2388:35. PubMed
  168. Xin B, et al. 2022. Hepatology. 76:630. PubMed
  169. Meng J, et al. 2022. Cell Rep. 38:110492. PubMed
  170. Yan Y, et al. 2022. Cell Death Differ. 29:1769. PubMed
  171. Li Y, et al. 2022. J Exp Clin Cancer Res. 41:128. PubMed
  172. Campisi L, et al. 2022. Nature. 606:945. PubMed
  173. Que W, et al. 2022. Sci Adv. 8:eabo4413. PubMed
  174. Xia KS, et al. 2023. Bioact Mater. 21:69. PubMed
  175. Kang IH, et al. 2022. iScience. 25:104818. PubMed
  176. Liu M, et al. 2022. Cells. 11: . PubMed
  177. Cagle LA, et al. 2023. Front Physiol. 13:1059686. PubMed
  178. Kasuya T, et al. 2023. Sci Rep. 13:1653. PubMed
  179. Scherer S, et al. 2023. Nat Immunol. 24:501. PubMed
  180. Jiang L, et al. 2021. Nano Today. 36:. PubMed
  181. Kodali S, et al. 2022. J Immunol. 208:1085. PubMed
  182. Bajaj R, et al. 2022. Cell Rep. 40:111429. PubMed
  183. Barsheshet Y, et al. 2022. Int J Mol Sci. 23:. PubMed
  184. Che L, et al. 2023. Foods. 12:. PubMed
  185. Giampaolo S, et al. 2023. iScience. 26:106234. PubMed
  186. van Os BW, et al. 2023. Eur Heart J Open. 3:oead013. PubMed
  187. Liu Y, et al. 2023. Cancers (Basel). 15:. PubMed
  188. Ben-Yaakov H, et al. 2023. Cancers (Basel). 15:. PubMed
  189. Tarafder S, et al. 2023. Bioact Mater. 28:61. PubMed
  190. Tai W, et al. 2023. Nat Commun. 14:2962. PubMed
  191. Yen FC, et al. 2023. Nat Commun. 14:2942. PubMed
  192. Hu Y, et al. 2023. JCI Insight. 8:. PubMed
  193. Pettini E, et al. 2021. Vaccines (Basel). 9:. PubMed
  194. Bergot AS, et al. 2020. J Immunol. 204:1787. PubMed
  195. Bussières-Marmen S, et al. 2017. Cell Mol Immunol. 10.1038/cmi.2016.72. PubMed
  196. Pennock N, et al. 2014. Proc Natl Acad Sci U S A. 111:16472. PubMed
  197. Chen H, et al. 2005. J Immunol. 175:591. PubMed
  198. Viny AD, et al. 2019. Cell Stem Cell. 25:682. PubMed
  199. Shibata K, et al. 2022. Nat Commun. 13:6948. PubMed
  200. Kurosawa M, et al. 2021. Int J Mol Sci. 22:. PubMed
  201. Hamilton JAG, et al. 2021. Aging Cell. 20:e13309. PubMed
  202. Lechuga-Vieco AV, et al. 2020. Sci Adv. 6:eaba5345. PubMed
  203. Gupta SS, et al. 2019. Cell Rep. 29:1862. PubMed
  204. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  205. Liu QZ, et al. 2018. Front Immunol. 1.131944444. PubMed
  206. Nair N, et al. 2020. Curr Protoc Microbiol. 59:e127. PubMed
  207. Christian LS, et al. 2021. Cell Reports. 35(6):109118. PubMed
  208. Limon JJ et al. 2019. Cell host & microbe. 25(3):377-388 . PubMed
  209. Li J, et al. 2022. Int J Biol Sci. 18:2091. PubMed
  210. Menzel L, et al. 2021. Cell Rep. 37:109878. PubMed
  211. Ma C, et al. 2021. Signal Transduct Target Ther. 6:353. PubMed
  212. Plumlee CR, et al. 2020. Cell Host Microbe. 29(1):68-82.e5. PubMed
  213. Yasuoka T, et al. 2016. PLoS One. 11: 0157395. PubMed
  214. Wang Y, et al. 2016. Sci Rep. 6:31881. PubMed
  215. García Nores GD, et al. 2018. Nat Commun. 9:1970. PubMed
  216. Ogawa C et al. 2018. Cell reports. 25(1):19-28 . PubMed
  217. Murphy M, et al. 2017. Eur J Immunol. 47:880. PubMed
  218. Harada Y, et al. 2022. iScience. 25:104021. PubMed
  219. Zhang Q, et al. 2021. Nat Commun. 12:4592. PubMed
  220. Voga M, et al. 2021. Front Vet Sci. 7:610240. PubMed
  221. Inoue D, et al. 2021. Nat Genet. 53:707. PubMed
  222. Flaherty S, Reynolds J 2015. J Vis Exp. 98: 52739. PubMed
  223. Ni F, et al. 2019. Cell Stem Cell. 24:608. PubMed
  224. Sumigray KD et al. 2018. Developmental cell. 45(2):183-197 . PubMed
  225. Liu H, et al. 2022. Nat Commun. 13:3684. PubMed
  226. Geiger R, et al. 2016. Cell. 167:829-842. PubMed
  227. Arandjelovic S, et al. 2010. J Leukoc Biol. 88:737. PubMed
  228. Lo PK, et al. 2018. Elife. 7:e31334. PubMed
  229. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  230. Perry JSA, et al. 2018. Immunity. 48:923. PubMed
  231. Han Y, et al. 2019. Am J Cancer Res. 9:800. PubMed
  232. Yang K, et al. 2022. J Clin Invest. 132:. PubMed
  233. Wang B, et al. 2022. Nat Commun. 13:3821. PubMed
  234. Li J, et al. 2020. Cancer Discov. . PubMed
  235. Pereira JL, et al. 2021. Transl Oncol. 14:101125. PubMed
  236. Maluski M, et al. 2019. J Clin Invest. 129:5108. PubMed
  237. Cheng HW, et al. 2019. Nat Commun. 10:1739. PubMed
  238. Yin Q, et al. 2021. Proc Natl Acad Sci U S A. 118: . PubMed
  239. Skordos I, et al. 2021. STAR Protocols. 2(1):100351. PubMed
  240. Uhde A, et al. 2016. PLoS One. 11: 0161883. PubMed
  241. Kim HR, et al. 2018. Nat Commun. 9:3630. PubMed
  242. Lee CG, et al. 2019. JCI Insight. 4:5. PubMed
  243. Santos CP et al. 2019. Nat Commun. 10(1):4407 . PubMed
  244. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  245. Garhyan J, et al. 2015. Am J Pathol. 185: 1924-1934. PubMed
  246. Dai B, et al. 2012. Mol Ther. 20:1800. PubMed
  247. Place D, et al. 2017. PLoS One. 10.1371/journal.pone.0190384. PubMed
  248. Bankoti R, et al. 2017. Sci Rep. 10.1038/s41598-017-12171-3. PubMed
  249. Florêncio KGD, et al. 2022. Front Immunol. 13:941757. PubMed
  250. Hu Y, et al. 2022. J Nanobiotechnology. 20:417. PubMed
  251. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  252. Kenswil KJG, et al. 2021. Cell Stem Cell. 28(4):653-670.e11. PubMed
  253. Tartey S, et al. 2021. Cancer Research. 81(9):2358-2372. PubMed
  254. Barsoumian HB, et al. 2020. J Immunother Cancer. 8:00. PubMed
  255. Flosbach M, et al. 2020. Cell Reports. 32(4):107957. PubMed
  256. Daly CS, et al. 2018. Oncol Rep. 39:483. PubMed
  257. Kang DW, et al. 2020. J Pathol. 252:304. PubMed
  258. Huang Z, et al. 2021. Nat Commun. 12:145. PubMed
  259. Lee L, et al. 2016. PLoS One. 11:e0167693. PubMed
  260. Naik A, et al. 2015. J Immunol. 194:790. PubMed
  261. Godavarthy PS, et al. 2019. Haematologica. 104(10). PubMed
  262. Clark GC, et al. 2022. Front Oncol. 12:913656. PubMed
  263. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  264. Long H, et al. 2022. Oncol Lett. 23:95. PubMed
  265. Xiao S, et al. 2020. Cell Reports. 32(2):107892. PubMed
  266. Karandikar SH, et al. 2019. JCI Insight. 5. PubMed
  267. Yang BH, et al. 2020. Cell Reports. 27(12):3629-3645.e6.. PubMed
  268. Cañadas I, et al. 2018. Nat Med. 24:1143. PubMed
  269. Akkaya B, et al. 2017. J Immunol Methods. 441:67. PubMed
  270. Guo S, et al. 2021. Sci Rep. 11:23745. PubMed
  271. Liu S, et al. 2022. J Neuroinflammation. 19:35. PubMed
  272. Li J, et al. 2022. Nat Commun. 13:4032. PubMed
  273. Fei W, et al. 2022. Int J Stem Cells. :. PubMed
  274. Wang YT, et al. 2020. Nat Microbiol. 0.397222222. PubMed
  275. Gao Y, et al. 2020. Immunity. 52(6):1007-1021.e8. PubMed
  276. Pastushenko I, et al. 2020. Nature. 589:448. PubMed
  277. Thakur A, et al. 2018. Front Immunol. 2.336805556. PubMed
  278. Jimenez H, et al. 2019. EBioMedicine. 44:209. PubMed
  279. Revathikumar P, et al. 2018. PLoS One. 13:e0193210. PubMed
  280. King R, et al. 2021. Sci Adv. 7:eabj5293. PubMed
  281. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  282. Magness S, et al. 2013. Am J Physiol Gastrointest Liver Physiol. 305:542. PubMed
  283. Jeljeli M, et al. 2021. Front Immunol. 12:670776. PubMed
  284. Tian Q, et al. 2022. Cell Death Dis. 13:71. PubMed
  285. Wang D, et al. 2022. EMBO Rep. 23:e53691. PubMed
  286. Li M, et al. 2021. Br J Pharmacol. 178:2617. PubMed
  287. Younes AI, et al. 2021. Transl Oncol. 14:100983. PubMed
  288. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
  289. Zhang H, et al. 2021. Cell Reports. 35(6):109096. PubMed
  290. Wedekind MF, et al. 2021. iScience. 24(7):102759. PubMed
  291. Zheng B, et al. 2021. Bioact Mater. 6:3879. PubMed
  292. Shissler SC, et al. 2020. Sci Rep. 10:8218. PubMed
  293. Yamazaki M, et al. 2021. Biomedicines. 9:. PubMed
  294. Mairhofer D, et al. 2015. J Invest Dermatol. 135: 2785-93. PubMed
  295. Lau J, et al. 2015. Cancer Res . 75: 4302 - 4311. PubMed
  296. Ma Q, et al. 2022. Vaccines (Basel). 10:. PubMed
  297. Byrne K, et al. 2014. J Immunol. 192:1433. PubMed
  298. Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed
  299. Xu Y, et al. 2016. Nat Commun. 7:12073. PubMed
  300. Kobayashi A, et al. 2011. J Exp Med. 208:2641. PubMed
  301. Hwang WL, et al. 2019. J Hematol Oncol. 12:10. PubMed
  302. Sun Y, et al. 2020. J Immunol. 205:2649. PubMed
  303. Mizuno M, et al. 2021. Cancers (Basel). 13:. PubMed
  304. Norgard RJ, et al. 2021. EMBO Rep. 22:e51872. PubMed
  305. Xu W, et al. 2021. Immunity. 54(3):526-541.e7. PubMed
  306. Parks CA, et al. 2019. Proc Natl Acad Sci U S A. 116:3136. PubMed
  307. Shah D, et al. 2018. Clin Cancer Res. 24:4566. PubMed
  308. Teng F, et al. 2021. Cell Rep. 37:110051. PubMed
  309. Endo-Umeda K, et al. 2021. Sci Rep. 11:22595. PubMed
  310. Weber K, et al. 2008. J Immunol. 180:1442. PubMed
  311. Gejman RS et al. 2018. eLife. 7 pii: e41090. PubMed
  312. Deptuch T, et al. 2022. Sci Rep. 12:13480. PubMed
  313. Hu Y, et al. 2021. J Nanobiotechnology. 19:416. PubMed
  314. Kerdidani D, et al. 2022. J Exp Med. 219:. PubMed
  315. Funk KE, et al. 2021. Aging Cell. 20:e13412. PubMed
  316. Gawish R, et al. 2022. Elife. 11:. PubMed
  317. Lei F, et al. 2012. J Vis Exp. 63: 3986. PubMed
  318. Liu WL, et al. 2019. Nat Commun. 10:3199. PubMed
  319. Cao Y, et al. 2022. Small. 18:e2203466. PubMed
  320. Plaza-Sirvent C, et al. 2021. Front Immunol. 12:705436. PubMed
  321. Wang W, et al. 2022. Oxid Med Cell Longev. 2022:8172866. PubMed
  322. Swanson WB, et al. 2021. Biomaterials. 272:120769. PubMed
  323. Avgustinova A, et al. 2021. Cell Stem Cell. . PubMed
  324. Guo S, et al. 2021. Frontiers in Immunology. 11:614667. PubMed
RRID
AB_312962 (BioLegend Cat. No. 103011)
AB_312963 (BioLegend Cat. No. 103012)

Antigen Details

Structure
Variable splicing of CD44 gene generates many CD44 isoforms, 80-95 kD
Distribution

All leukocytes, epithelial cells, endothelial cells, hepatocytes, mesenchymal cells

Function
Leukocyte attachment and rolling on endothelial cells, stromal cells and ECM
Ligand/Receptor
Hyaluronan, MIP-1β, fibronectin, collagen
Cell Type
B cells, Endothelial cells, Epithelial cells, Leukocytes, Mesenchymal cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Immunology, Stem Cells
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Haynes BF, et al. 1991. Cancer Cells 3:347.
3. Goldstein LA, et al. 1989. Cell 56:1063.
4. Mikecz K, et al. 1995. Nat. Med. 1:558.
5. Hegde V, et al. 2008. J. Leukocyte Biol. 84:134.
6. Liu T, et al. 2009. Biol. Direct 4:40.

Gene ID
12505 View all products for this Gene ID 960 View all products for this Gene ID
UniProt
View information about CD44 on UniProt.org

Other Formats

View All CD44 Reagents Request Custom Conjugation
Description Clone Applications
PE/Dazzle™ 594 anti-mouse/human CD44 IM7 FC
Brilliant Violet 711™ anti-mouse/human CD44 IM7 FC
APC/Fire™ 750 anti-mouse/human CD44 IM7 FC
TotalSeq™-A0073 anti-mouse/human CD44 IM7 PG
TotalSeq™-C0073 anti-mouse/human CD44 IM7 PG
TotalSeq™-B0073 anti-mouse/human CD44 IM7 PG
Spark YG™ 570 anti-mouse/human CD44 IM7 FC,IHC-P
Spark YG™ 593 anti-mouse/human CD44 IM7 FC
TotalSeq™-D0073 anti-mouse/human CD44 IM7 PG
PE anti-mouse/human CD44 IM7 FC
Brilliant Violet 750™ anti-mouse/human CD44 IM7 FC
PerCP/Fire™ 806 anti-mouse/human CD44 IM7 FC
Spark Red™ 718 anti-mouse/human CD44 IM7 FC
PE/Fire™ 810 anti-mouse/human CD44 IM7 FC
Spark Blue™ 550 anti-mouse/human CD44 (Flexi-Fluor™) IM7 FC
Spark YG™ 581 anti-mouse/human CD44 (Flexi-Fluor™) IM7 FC
Spark NIR™ 685 anti-mouse/human CD44 (Flexi-Fluor™) Antibody IM7 FC
Spark UV™ 387 anti-mouse/human CD44 (Flexi-Fluor™) IM7 FC
StarBright UltraViolet 795 anti-mouse/human CD44 IM7 FC
Alexa Fluor® 488 anti-mouse/human CD44 IM7 FC,ICC,IHC-P,SB
Alexa Fluor® 647 anti-mouse/human CD44 IM7 FC,ICC,SB
Pacific Blue™ anti-mouse/human CD44 IM7 FC
APC anti-mouse/human CD44 IM7 FC
Biotin anti-mouse/human CD44 IM7 FC,ICC,IHC-P
FITC anti-mouse/human CD44 IM7 FC,ICC,IHC-P
PE/Cyanine5 anti-mouse/human CD44 IM7 FC
Purified anti-mouse/human CD44 IM7 FC,IHC-F,CyTOF®,ELISA,ICC,IHC-P,IP,CMCD,Stim
Alexa Fluor® 700 anti-mouse/human CD44 IM7 FC,SB
PE/Cyanine7 anti-mouse/human CD44 IM7 FC
APC/Cyanine7 anti-mouse/human CD44 IM7 FC
PerCP/Cyanine5.5 anti-mouse/human CD44 IM7 FC
PerCP anti-mouse/human CD44 IM7 FC
Brilliant Violet 421™ anti-mouse/human CD44 IM7 FC,ICC,IHC-P
Brilliant Violet 570™ anti-mouse/human CD44 IM7 FC
Brilliant Violet 785™ anti-mouse/human CD44 IM7 FC
Brilliant Violet 510™ anti-mouse/human CD44 IM7 FC
Ultra-LEAF™ Purified anti-mouse/human CD44 IM7 FC,CyTOF®,ELISA,IHC,IP,CMCD,Stim
Brilliant Violet 605™ anti-mouse/human CD44 IM7 FC
Brilliant Violet 650™ anti-mouse/human CD44 IM7 FC
Purified anti-mouse/human CD44 (Maxpar® Ready) IM7 FC,CyTOF®
Alexa Fluor® 594 anti-mouse/human CD44 IM7 ICC,FC,IHC-P,SB
Go To Top Version: 2    Revision Date: 09.11.2014

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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