Loading...

FITC anti-mouse CD3ε Antibody FITC anti-mouse CD3ε Antibody

Pricing & Availability
Clone
145-2C11 (See other available formats)
Regulatory Status
RUO
Other Names
CD3ε, T3, CD3
Isotype
Armenian Hamster IgG
Ave. Rating
Submit a Review
Product Citations
publications
145-2C11_FITC_021606
C57BL/6 mouse splenocytes were stained with CD3e (clone 145-2C11) FITC and CD127 (clone SB/199) PE.
  • 145-2C11_FITC_021606
    C57BL/6 mouse splenocytes were stained with CD3e (clone 145-2C11) FITC and CD127 (clone SB/199) PE.
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability Save
100305 50 µg NOK248
Check Availability


Need larger quantities of this item?
Request Bulk Quote
100306 500 µg NOK817
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
H-2Kb-specific mouse cytotoxic T lymphocyte clone BM10-37
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone 145-2C11 is useful for in vitro blocking of target-specific CTL-mediated cell lysis1, as well as T cell activation assays, inducing proliferation and cytokine production1,2,7,12,16. It also induces apoptosis in immature thymocytes32,  and in vivo T cell depletion8-10. Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1, immunohistochemical staining14,15 of acetone-fixed frozen sections and zinc-fixed paraffin-embedded sections, Western blotting4, complement-mediated cytotoxicity6, in vitro and in vivo stimulation of T cells1,2,7,12,16, immunofluorescent staining5, and in vivo T cell depletion8-10. The 145-2C11 antibody has been reported to block the binding of 17A2 antibody to CD3 epsilon-specific T cells11. Clone 145-2C11 is not recommended for formalin-fixed paraffin embedded sections. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 100314). For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 100340) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).

Application References
  1. Leo O, et al. 1987. P. Natl. Acad. Sci. USA 84:1374. (IP, Activ, Block)
  2. Kruisbeek AM, et al. 1991. In Current Protocols in Immunology. 3.12.1. (Activ)
  3. Duke RC, et al. 1995. Current Protocols in Immunology. 3.17.1.
  4. Salvadori S, et al. 1994. J. Immunol. 153:5176. (WB)
  5. Payer E, et al. 1991. J. Immunol. 146:2536. (IF)
  6. Jacobs H, et al. 1994. Eur. J. Immunol. 24:934. (CMCD)
  7. Vossen ACTM, et al. 1995. Eur. J. Immunol. 25:1492. (Activ)
  8. Henrickson M, et al. 1995. Transplantation 60:828. (Deplete)
  9. Kinnaert P, et al. 1996. Transpl. Int. 9:386. (Deplete)
  10. Han WR, et al. 1999. Transpl. Immunol. 7:207. (Deplete)
  11. Miescher GC, et al. 1989. Immunol. Lett. 23:113. (Block)
  12. Terrazas LI, et al. 2005. Intl. J. Parasitology. 35:1349. (Activ)
  13. Ko SY, et al. 2005. J. Immunol. 175:3309.
  14. Podd BS, et al. 2006. J. Immunol. 176:6532. (IHC-F)
  15. Tilley SL, et al. 2007. J. Immunol. 178:3208. (IHC-F)
  16. Wang W, et al. 2007. J. Immunol. 178:4885. (Activ)
  17. Xiao S, et al. 2007. J. Exp. Med. 204:1691.
  18. Chappaz S, et al. 2007. Blood doi:10.1182/blood-2007-02-074245. (FC) PubMed.
  19. Curtsinger JM, et al.2005. J. Immunol. 175:4392. PubMed
  20. Guo Y, et al. 2008. Blood 112:480. PubMed
  21. Kenna TJ, et al. 2008. Blood 111:2091.
  22. Perchonock CE, et al. 2007. J. Immunol. 179:1768. PubMed
  23. Perchonock GE, et al. 2006. Mol. Cell. Biol. 26:6005. PubMed
  24. Kanaya T, et al. 2008. Am. J. Physiol. Gastrointest. Liver Physiol. 295:G273. PubMed
  25. de Koning BA, et al. 2006. Int. Immunol. 18:941. PubMed
  26. Schulteis RD, et al. 2008. Blood 295:G273. PubMed
  27. Qi Q, et al. 2009. Blood 114:564. PubMed
  28. Helmersson S, et al. 2013. Am J Pathol. 9440:123. Pubmed
  29. Wu S, et al. 2014. Clin Vaccine Immunol. 21:156. PubMed
  30. Yan J, et al. 2014. Vaccine. 32:2833. PubMed
  31. Guiterrez DA, et al. 2014. Diaebetes. 63:3827. PubMed
  32. Shi YF, et al. 1991. J Immunol. 146:3340. (Apop)
Product Citations
  1. Chei S, et al. 2020. Front Nutr. 7:583186. PubMed
  2. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  3. Bertrand F, et al. 2017. Nat Commun. 8:2256. PubMed
  4. Katsumura KR, et al. 2018. Proc Natl Acad Sci U S A. 115:E10109. PubMed
  5. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  6. Russler-Germain EV, et al. 2021. Immunity. 54:2547. PubMed
  7. Li DD, et al. 2022. J Cell Mol Med. 26:2438. PubMed
  8. Jou E, et al. 2022. Sci Immunol. 7:eabn0175. PubMed
  9. Zhao X, et al. 2022. STAR Protoc. 3:101859. PubMed
  10. Yang L, et al. 2023. Acta Pharmacol Sin. :. PubMed
  11. Lu T, et al. 2023. Cancer Immunol Immunother. :. PubMed
  12. Smith LA, et al. 2023. Front Oncol. 12:1031174. PubMed
  13. Murakata Y, et al. 2023. Front Cardiovasc Med. 9:1075358. PubMed
  14. Jerome JR, et al. 2023. Int J Mol Sci. 24: . PubMed
  15. Drijvers JM, et al. 2021. Cancer Immunol Res. 9:184. PubMed
  16. Glorieux C, et al. 2022. J Adv Res. 40:109. PubMed
  17. Wu R, et al. 2022. Nat Immunol. 23:1536. PubMed
  18. Lu C, et al. 2023. Antiviral Res. 212:105556. PubMed
  19. Wang JX, et al. 2023. JCI Insight. 8:. PubMed
  20. Wu Y, et al. 2023. Nat Cancer. 4:382. PubMed
  21. Brunner SM, et al. 2023. Int J Mol Sci. 24:. PubMed
  22. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  23. Stitzlein LM, et al. 2023. Front Neurol. 14:1112207. PubMed
  24. van Os BW, et al. 2023. Front Cardiovasc Med. 10:1171764. PubMed
  25. Ye S, et al. 2023. Front Oncol. 13:1202750. PubMed
  26. Lentucci C, et al. 2017. J Biol Chem. 292:2754-2772. PubMed
  27. Schulteis R, et al. 2008. Blood. 112:4905. PubMed
  28. Wang L, et al. 2019. Cell Rep. 29:1848. PubMed
  29. Groza D, et al. 2018. Oncoimmunology. 7:e1424676. PubMed
  30. Zhou J, et al. 2021. Int J Med Sci. 18:3516. PubMed
  31. Fornari T, et al. 2015. PLoS One. 10: 0142688. PubMed
  32. Koning B, et al. 2006. Int Immunol. 1.403472222. PubMed
  33. Hewitson JP, et al. 2020. J Immunol. 204:2949. PubMed
  34. Johnson KD, et al. 2022. Blood Adv. 6:1464. PubMed
  35. Lou F, et al. 2020. STAR Protoc. 1:100115. PubMed
  36. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  37. Gruber T, et al. 2020. JCI Insight. 5:00. PubMed
  38. Allegrezza M, et al. 2016. Cancer Res . 76: 6253 - 6265. PubMed
  39. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  40. Isoda T et al. 2017. Cell. 171(1):103-119 . PubMed
  41. Waide ML, et al. 2020. Cell Rep. 33:108503. PubMed
  42. Kremenovic M, et al. 2022. J Immunother Cancer. 10:. PubMed
  43. Tian H, et al. 2022. Cancer Sci. 113:875. PubMed
  44. Bartleson JM, et al. 2020. Nat Immunol. 1384:21. PubMed
  45. Hung PJ, et al. 2018. Mol Cell. 71:332. PubMed
  46. Patnode M, et al. 2013. Glycobiology. 23:381. PubMed
  47. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
  48. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  49. Yi M, et al. 2021. J Hematol Oncol. 14:27. PubMed
  50. Zhang X, et al. 2020. J Immunol. 205:1743. PubMed
  51. Peng L, et al. 2020. Transl Lung Cancer Res. 0.892361111. PubMed
  52. Best SA, et al. 2018. Cell Metab. 27:935. PubMed
  53. Uchida A, et al. 2021. J Inflamm Res. 14:3089. PubMed
  54. Sato Y, et al. 2021. J Clin Invest. Online ahead of print. PubMed
  55. Pereira JL, et al. 2021. Transl Oncol. 14:101125. PubMed
  56. Collin R, et al. 2014. J Immunol. 193:3503. PubMed
  57. Yin Q, et al. 2015. PLoS One. 10: 0137808. PubMed
  58. Ma Y, et al. 2015. J Immunol. 195: 3769 - 3780. PubMed
  59. Matsumura K, et al. 2016. J Immunol. 197: 3233 - 3244. PubMed
  60. Qi X, et al. 2019. Nat Med. 25:1225. PubMed
  61. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  62. Lin JR et al. 2018. eLife. 7 pii: e31657. PubMed
  63. Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed
  64. Li H, et al. 2022. Theranostics. 12:6422. PubMed
  65. Jeong SH, et al. 2021. Nat Commun. 12:4405. PubMed
  66. Huang Y, et al. 2020. FASEB J. 34:1768. PubMed
  67. Kawakami R, et al. 2021. Immunity. 54(5):947-961.e8. PubMed
  68. Burrack K, et al. 2015. PLoS Pathog. 11: e1005191. PubMed
  69. Skeate JG, et al. 2018. PLoS One. 13:e0191311. PubMed
  70. He L, et al. 2019. iScience. 0.790972222. PubMed
  71. Cheng HW, et al. 2019. Nat Commun. 10:1739. PubMed
  72. Cong J et al. 2018. Cell metabolism. 28(2):243-255 . PubMed
  73. Tang CC, et al. 2021. eLife. 10:00. PubMed
  74. Gong Y, et al. 2020. Cell Metabolism. 33(1):51-64.e9. PubMed
  75. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  76. Souza COS, et al. 2021. iScience. 24(6):102548. PubMed
  77. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  78. Miki Y, et al. 2016. J Biol Chem. 291: 15588 - 15601. PubMed
  79. Knolle MD et al. 2018. Frontiers in immunology. 1.925 . PubMed
  80. Doonan J, et al. 2019. Nat Commun. 10:1554. PubMed
  81. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  82. Russler-Germain EV, et al. 2021. Elife. 10:. PubMed
  83. Pardy RD, et al. 2021. Nat Commun. 12:4051. PubMed
  84. Yang H, et al. 2022. Nutrients. 14:. PubMed
  85. Kondratieva T, et al. 2020. PLoS One. 15:e0239668. PubMed
  86. Ringel AE, et al. 2020. Cell. 183(7):1848-1866.e26. PubMed
  87. Yi X, et al. 2020. Sci Adv. 6:eaba3546. PubMed
  88. Burrack K, et al. 2015. J Immunol. 194:678. PubMed
  89. Siamishi I, et al. 2020. Cell Reports. 31(11):107756. PubMed
  90. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  91. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  92. Stotesbury C, et al. 2020. J Immunol. 204:1582. PubMed
  93. Wanner-Seleznik GM, et al. 2020. Immunohorizons. 0.644444444. PubMed
  94. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  95. Kim SH, et al. 2021. Cell Reports. 35(2):108995. PubMed
  96. Kacherovsky N, et al. 2019. Nat Biomed Eng. 0.66875. PubMed
  97. Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
  98. Murakami K, et al. 2021. Cell Reports. 34(1):108579. PubMed
  99. Ni J, et al. 2020. Immunity. 52(6):1075-1087.e8. PubMed
  100. Bian G, et al. 2020. British Journal of Pharmacology. 178(3):636-653. PubMed
  101. Galle-Treger L, et al. 2016. Nat Commun. 7:13202. PubMed
  102. Sendler M, et al. 2020. Gastroenterology. 158:253. PubMed
  103. Denny JE, et al. 2019. Sci Rep. 2.786111111. PubMed
  104. Kim MY, et al. 2017. Plant Biotechnol J. 1.729166667. PubMed
  105. Huang J, et al. 2014. J Immunol. 192:1972. PubMed
  106. Xu M, et al. 2013. J Immunol. 190:5436. PubMed
  107. Xu Q, et al. 2021. Theranostics. 11:1937. PubMed
  108. Zhang P, et al. 2022. Nat Commun. 13:1588. PubMed
  109. Vacca F, et al. 2020. eLife. 9:e54017.. PubMed
  110. Labiano S, et al. 2017. Oncoimmunology. 6:e1283468. PubMed
  111. Engblom C, et al. 2017. Science. 358:6367. PubMed
  112. Baomei Wang et al. 2019. Cell reports. 26(6):1614-1626 . PubMed
  113. Lind L, et al. 2021. J Neurovirol. 27:145. PubMed
  114. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  115. Eisemann T, et al. 2019. Front Oncol. 9:187. PubMed
  116. Yue W, et al. 2019. Nat Commun. 10:2025. PubMed
  117. Oliveira AC et al. 2017. eLife. 6 pii: e30883. PubMed
  118. Agrawal M, et al. 2022. Blood. 140:1094. PubMed
  119. Zhao X, et al. 2022. iScience. 25:104690. PubMed
  120. Soria-Castro R, et al. 2020. Sci Rep. 10:17802. PubMed
  121. Casselli T, et al. 2021. PLoS Pathog. 17:e1009256. PubMed
  122. Okada R, et al. 2021. EBioMedicine. 67:103345. PubMed
  123. Luo L, et al. 2021. J Neuroinflammation. 18:27. PubMed
  124. Damgaard RB et al. 2016. Cell. 166(5):1215-1230 . PubMed
  125. Baglaenko Y, et al. 2016. PLoS One. 11: 0150515. PubMed
  126. Wang J, et al. 2019. Aging (Albany NY). 11:3463. PubMed
  127. Lin JC, et al. 2019. Nat Commun. 10:1057. PubMed
  128. Liu Y, et al. 2018. Cancer Cell. 33:480. PubMed
  129. Sánchez-del-Campo L, et al. 2021. J Exp Clin Cancer Res. 40:117. PubMed
  130. Okuyama Y, et al. 2020. FASEB J. 540:34. PubMed
  131. La Salvia S, et al. 2020. Am J Physiol Renal Physiol. 319:F868. PubMed
  132. Sparber F, et al. 2019. Cell Host Microbe. 25:389. PubMed
  133. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  134. Fitzpatrick Z, et al. 2020. Nature. 587:472. PubMed
  135. Srivastava S, et al. 2020. Cancer Cell. 39(2):193-208.e10. PubMed
  136. Sheng J, et al. 2021. eLife. 10:00. PubMed
  137. Nakagawa Y, et al. 2015. Immunol Lett. 167: 72-86. PubMed
  138. Ikeda T, et al. 2014. PLoS One. 9:115198. PubMed
  139. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  140. Tippimanchai DD, et al. 2018. Oncoimmunology. 7:e1438105. PubMed
  141. Schofield L, et al. 2017. BMC Med. 10.1186/s12916-017-0883-8. PubMed
  142. Oh J, et al. 2021. Clin Cancer Res. 27:4781. PubMed
  143. Harding CL, et al. 2020. Front Cell Infect Microbiol. 10:328. PubMed
  144. Xiao Z, et al. 2022. Mater Today Bio. 15:100297. PubMed
  145. Ma C, et al. 2021. Mol Metab. 47:101170. PubMed
  146. Tian T, et al. 2020. Cancer Immunol Res. 660:8. PubMed
  147. Zhou X, et al. 2021. Nutr Metab (Lond). 18:64. PubMed
  148. Zhang S, et al. 2016. PLoS Pathog. 12: 1005617. PubMed
  149. L M, et al. 2016. Brain. 139: 1939-1957. PubMed
  150. Krotova K, et al. 2019. Mol Ther Oncolytics. 15:166. PubMed
  151. Lai NY, et al. 2020. Cell. 180:33:00. PubMed
  152. Kanaya T, et al. 2008. Am J Physiol Gastrointest Liver Physiol. 295:273. PubMed
  153. Hilt ZT, et al. 2019. JCI Insight. 4:5. PubMed
  154. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  155. Rivera CA, et al. 2022. Immunity. 55:129. PubMed
  156. Awida Z, et al. 2021. Int J Mol Sci. 23:. PubMed
  157. Amatruda M, et al. 2022. Brain Commun. 4:fcac044. PubMed
  158. Aggarwal N, et al. 2021. Cell Rep. 37:110170. PubMed
  159. Chei S, et al. 2020. Front Nutr. 7:583186. PubMed
  160. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  161. Bertrand F, et al. 2017. Nat Commun. 8:2256. PubMed
  162. Katsumura KR, et al. 2018. Proc Natl Acad Sci U S A. 115:E10109. PubMed
  163. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  164. Russler-Germain EV, et al. 2021. Immunity. 54:2547. PubMed
  165. Li DD, et al. 2022. J Cell Mol Med. 26:2438. PubMed
  166. Jou E, et al. 2022. Sci Immunol. 7:eabn0175. PubMed
  167. Zhao X, et al. 2022. STAR Protoc. 3:101859. PubMed
  168. Yang L, et al. 2023. Acta Pharmacol Sin. :. PubMed
  169. Lu T, et al. 2023. Cancer Immunol Immunother. :. PubMed
  170. Smith LA, et al. 2023. Front Oncol. 12:1031174. PubMed
  171. Murakata Y, et al. 2023. Front Cardiovasc Med. 9:1075358. PubMed
  172. Jerome JR, et al. 2023. Int J Mol Sci. 24: . PubMed
  173. Drijvers JM, et al. 2021. Cancer Immunol Res. 9:184. PubMed
  174. Glorieux C, et al. 2022. J Adv Res. 40:109. PubMed
  175. Wu R, et al. 2022. Nat Immunol. 23:1536. PubMed
  176. Lu C, et al. 2023. Antiviral Res. 212:105556. PubMed
  177. Wang JX, et al. 2023. JCI Insight. 8:. PubMed
  178. Wu Y, et al. 2023. Nat Cancer. 4:382. PubMed
  179. Brunner SM, et al. 2023. Int J Mol Sci. 24:. PubMed
  180. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  181. Stitzlein LM, et al. 2023. Front Neurol. 14:1112207. PubMed
  182. van Os BW, et al. 2023. Front Cardiovasc Med. 10:1171764. PubMed
  183. Ye S, et al. 2023. Front Oncol. 13:1202750. PubMed
  184. Lentucci C, et al. 2017. J Biol Chem. 292:2754-2772. PubMed
  185. Schulteis R, et al. 2008. Blood. 112:4905. PubMed
  186. Wang L, et al. 2019. Cell Rep. 29:1848. PubMed
  187. Groza D, et al. 2018. Oncoimmunology. 7:e1424676. PubMed
  188. Zhou J, et al. 2021. Int J Med Sci. 18:3516. PubMed
  189. Fornari T, et al. 2015. PLoS One. 10: 0142688. PubMed
  190. Koning B, et al. 2006. Int Immunol. 1.403472222. PubMed
  191. Hewitson JP, et al. 2020. J Immunol. 204:2949. PubMed
  192. Johnson KD, et al. 2022. Blood Adv. 6:1464. PubMed
  193. Lou F, et al. 2020. STAR Protoc. 1:100115. PubMed
  194. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  195. Gruber T, et al. 2020. JCI Insight. 5:00. PubMed
  196. Allegrezza M, et al. 2016. Cancer Res . 76: 6253 - 6265. PubMed
  197. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  198. Isoda T et al. 2017. Cell. 171(1):103-119 . PubMed
  199. Waide ML, et al. 2020. Cell Rep. 33:108503. PubMed
  200. Kremenovic M, et al. 2022. J Immunother Cancer. 10:. PubMed
  201. Tian H, et al. 2022. Cancer Sci. 113:875. PubMed
  202. Bartleson JM, et al. 2020. Nat Immunol. 1384:21. PubMed
  203. Hung PJ, et al. 2018. Mol Cell. 71:332. PubMed
  204. Patnode M, et al. 2013. Glycobiology. 23:381. PubMed
  205. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
  206. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  207. Yi M, et al. 2021. J Hematol Oncol. 14:27. PubMed
  208. Zhang X, et al. 2020. J Immunol. 205:1743. PubMed
  209. Peng L, et al. 2020. Transl Lung Cancer Res. 0.892361111. PubMed
  210. Best SA, et al. 2018. Cell Metab. 27:935. PubMed
  211. Uchida A, et al. 2021. J Inflamm Res. 14:3089. PubMed
  212. Sato Y, et al. 2021. J Clin Invest. Online ahead of print. PubMed
  213. Pereira JL, et al. 2021. Transl Oncol. 14:101125. PubMed
  214. Collin R, et al. 2014. J Immunol. 193:3503. PubMed
  215. Yin Q, et al. 2015. PLoS One. 10: 0137808. PubMed
  216. Ma Y, et al. 2015. J Immunol. 195: 3769 - 3780. PubMed
  217. Matsumura K, et al. 2016. J Immunol. 197: 3233 - 3244. PubMed
  218. Qi X, et al. 2019. Nat Med. 25:1225. PubMed
  219. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  220. Lin JR et al. 2018. eLife. 7 pii: e31657. PubMed
  221. Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed
  222. Li H, et al. 2022. Theranostics. 12:6422. PubMed
  223. Jeong SH, et al. 2021. Nat Commun. 12:4405. PubMed
  224. Huang Y, et al. 2020. FASEB J. 34:1768. PubMed
  225. Kawakami R, et al. 2021. Immunity. 54(5):947-961.e8. PubMed
  226. Burrack K, et al. 2015. PLoS Pathog. 11: e1005191. PubMed
  227. Skeate JG, et al. 2018. PLoS One. 13:e0191311. PubMed
  228. He L, et al. 2019. iScience. 0.790972222. PubMed
  229. Cheng HW, et al. 2019. Nat Commun. 10:1739. PubMed
  230. Cong J et al. 2018. Cell metabolism. 28(2):243-255 . PubMed
  231. Tang CC, et al. 2021. eLife. 10:00. PubMed
  232. Gong Y, et al. 2020. Cell Metabolism. 33(1):51-64.e9. PubMed
  233. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  234. Souza COS, et al. 2021. iScience. 24(6):102548. PubMed
  235. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  236. Miki Y, et al. 2016. J Biol Chem. 291: 15588 - 15601. PubMed
  237. Knolle MD et al. 2018. Frontiers in immunology. 1.925 . PubMed
  238. Doonan J, et al. 2019. Nat Commun. 10:1554. PubMed
  239. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  240. Russler-Germain EV, et al. 2021. Elife. 10:. PubMed
  241. Pardy RD, et al. 2021. Nat Commun. 12:4051. PubMed
  242. Yang H, et al. 2022. Nutrients. 14:. PubMed
  243. Kondratieva T, et al. 2020. PLoS One. 15:e0239668. PubMed
  244. Ringel AE, et al. 2020. Cell. 183(7):1848-1866.e26. PubMed
  245. Yi X, et al. 2020. Sci Adv. 6:eaba3546. PubMed
  246. Burrack K, et al. 2015. J Immunol. 194:678. PubMed
  247. Siamishi I, et al. 2020. Cell Reports. 31(11):107756. PubMed
  248. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  249. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  250. Stotesbury C, et al. 2020. J Immunol. 204:1582. PubMed
  251. Wanner-Seleznik GM, et al. 2020. Immunohorizons. 0.644444444. PubMed
  252. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  253. Kim SH, et al. 2021. Cell Reports. 35(2):108995. PubMed
  254. Kacherovsky N, et al. 2019. Nat Biomed Eng. 0.66875. PubMed
  255. Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
  256. Murakami K, et al. 2021. Cell Reports. 34(1):108579. PubMed
  257. Ni J, et al. 2020. Immunity. 52(6):1075-1087.e8. PubMed
  258. Bian G, et al. 2020. British Journal of Pharmacology. 178(3):636-653. PubMed
  259. Galle-Treger L, et al. 2016. Nat Commun. 7:13202. PubMed
  260. Sendler M, et al. 2020. Gastroenterology. 158:253. PubMed
  261. Denny JE, et al. 2019. Sci Rep. 2.786111111. PubMed
  262. Kim MY, et al. 2017. Plant Biotechnol J. 1.729166667. PubMed
  263. Huang J, et al. 2014. J Immunol. 192:1972. PubMed
  264. Xu M, et al. 2013. J Immunol. 190:5436. PubMed
  265. Xu Q, et al. 2021. Theranostics. 11:1937. PubMed
  266. Zhang P, et al. 2022. Nat Commun. 13:1588. PubMed
  267. Vacca F, et al. 2020. eLife. 9:e54017.. PubMed
  268. Labiano S, et al. 2017. Oncoimmunology. 6:e1283468. PubMed
  269. Engblom C, et al. 2017. Science. 358:6367. PubMed
  270. Baomei Wang et al. 2019. Cell reports. 26(6):1614-1626 . PubMed
  271. Lind L, et al. 2021. J Neurovirol. 27:145. PubMed
  272. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  273. Eisemann T, et al. 2019. Front Oncol. 9:187. PubMed
  274. Yue W, et al. 2019. Nat Commun. 10:2025. PubMed
  275. Oliveira AC et al. 2017. eLife. 6 pii: e30883. PubMed
  276. Agrawal M, et al. 2022. Blood. 140:1094. PubMed
  277. Zhao X, et al. 2022. iScience. 25:104690. PubMed
  278. Soria-Castro R, et al. 2020. Sci Rep. 10:17802. PubMed
  279. Casselli T, et al. 2021. PLoS Pathog. 17:e1009256. PubMed
  280. Okada R, et al. 2021. EBioMedicine. 67:103345. PubMed
  281. Luo L, et al. 2021. J Neuroinflammation. 18:27. PubMed
  282. Damgaard RB et al. 2016. Cell. 166(5):1215-1230 . PubMed
  283. Baglaenko Y, et al. 2016. PLoS One. 11: 0150515. PubMed
  284. Wang J, et al. 2019. Aging (Albany NY). 11:3463. PubMed
  285. Lin JC, et al. 2019. Nat Commun. 10:1057. PubMed
  286. Liu Y, et al. 2018. Cancer Cell. 33:480. PubMed
  287. Sánchez-del-Campo L, et al. 2021. J Exp Clin Cancer Res. 40:117. PubMed
  288. Okuyama Y, et al. 2020. FASEB J. 540:34. PubMed
  289. La Salvia S, et al. 2020. Am J Physiol Renal Physiol. 319:F868. PubMed
  290. Sparber F, et al. 2019. Cell Host Microbe. 25:389. PubMed
  291. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  292. Fitzpatrick Z, et al. 2020. Nature. 587:472. PubMed
  293. Srivastava S, et al. 2020. Cancer Cell. 39(2):193-208.e10. PubMed
  294. Sheng J, et al. 2021. eLife. 10:00. PubMed
  295. Nakagawa Y, et al. 2015. Immunol Lett. 167: 72-86. PubMed
  296. Ikeda T, et al. 2014. PLoS One. 9:115198. PubMed
  297. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  298. Tippimanchai DD, et al. 2018. Oncoimmunology. 7:e1438105. PubMed
  299. Schofield L, et al. 2017. BMC Med. 10.1186/s12916-017-0883-8. PubMed
  300. Oh J, et al. 2021. Clin Cancer Res. 27:4781. PubMed
  301. Harding CL, et al. 2020. Front Cell Infect Microbiol. 10:328. PubMed
  302. Xiao Z, et al. 2022. Mater Today Bio. 15:100297. PubMed
  303. Ma C, et al. 2021. Mol Metab. 47:101170. PubMed
  304. Tian T, et al. 2020. Cancer Immunol Res. 660:8. PubMed
  305. Zhou X, et al. 2021. Nutr Metab (Lond). 18:64. PubMed
  306. Zhang S, et al. 2016. PLoS Pathog. 12: 1005617. PubMed
  307. L M, et al. 2016. Brain. 139: 1939-1957. PubMed
  308. Krotova K, et al. 2019. Mol Ther Oncolytics. 15:166. PubMed
  309. Lai NY, et al. 2020. Cell. 180:33:00. PubMed
  310. Kanaya T, et al. 2008. Am J Physiol Gastrointest Liver Physiol. 295:273. PubMed
  311. Hilt ZT, et al. 2019. JCI Insight. 4:5. PubMed
  312. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  313. Rivera CA, et al. 2022. Immunity. 55:129. PubMed
  314. Awida Z, et al. 2021. Int J Mol Sci. 23:. PubMed
  315. Amatruda M, et al. 2022. Brain Commun. 4:fcac044. PubMed
  316. Aggarwal N, et al. 2021. Cell Rep. 37:110170. PubMed
RRID
AB_312670 (BioLegend Cat. No. 100305)
AB_312671 (BioLegend Cat. No. 100306)

Antigen Details

Structure
Ig superfamily, forms CD3/TCR complex with CD3δ, γ and ζ subunits and TCR (α/β and γ/δ), 20 kD
Distribution

Thymocytes (differentiation dependent), mature T cells, NK-T cells

Function
TCR signal transduction, T cell activation, antigen recognition
Ligand/Receptor
Peptide antigen/MHC-complex
Cell Type
NKT cells, T cells, Thymocytes, Tregs
Biology Area
Immunology
Molecular Family
CD Molecules, TCRs
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Davis MM. 1990. Annu. Rev. Biochem. 59:475.
3. Weiss A, et al. 1994. Cell 76:263.

Gene ID
12501 View all products for this Gene ID
UniProt
View information about CD3epsilon on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD3ε Reagents Request Custom Conjugation
Description Clone Applications
PE/Cyanine7 anti-mouse CD3ε 145-2C11 FC
Purified anti-mouse CD3ε (Maxpar® Ready) 145-2C11 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse CD3ε 145-2C11 FC
Brilliant Violet 510™ anti-mouse CD3ε 145-2C11 FC
Brilliant Violet 605™ anti-mouse CD3ε 145-2C11 FC
Brilliant Violet 711™ anti-mouse CD3ε 145-2C11 FC
Brilliant Violet 785™ anti-mouse CD3ε 145-2C11 FC
APC/Fire™ 750 anti-mouse CD3ε 145-2C11 FC
GoInVivo™ Purified anti-mouse CD3ε 145-2C11 FC
APC anti-mouse CD3ε 145-2C11 FC
Biotin anti-mouse CD3ε 145-2C11 FC,IHC-F
FITC anti-mouse CD3ε 145-2C11 FC
PE anti-mouse CD3ε 145-2C11 FC
PE/Cyanine5 anti-mouse CD3ε 145-2C11 FC
Purified anti-mouse CD3ε 145-2C11 FC,IHC-F,IP,Activ,Block,WB,ICC
Alexa Fluor® 488 anti-mouse CD3ε 145-2C11 FC
Alexa Fluor® 647 anti-mouse CD3ε 145-2C11 FC,IHC-F,3D IHC
PerCP anti-mouse CD3ε 145-2C11 FC
PerCP/Cyanine5.5 anti-mouse CD3ε 145-2C11 FC
APC/Cyanine7 anti-mouse CD3ε 145-2C11 FC
Pacific Blue™ anti-mouse CD3ε 145-2C11 FC
Brilliant Violet 421™ anti-mouse CD3ε 145-2C11 FC,ICC
Ultra-LEAF™ Purified anti-mouse CD3ε 145-2C11 FC,IHC-F,IP,Activ,Block,WB,ICC
Spark YG™ 593 anti-mouse CD3 145-2C11 FC
PerCP/Fire™ 780 anti-mouse CD3ε 145-2C11 FC
Brilliant Violet 650™ anti-mouse CD3ε 145-2C11 FC
Brilliant Violet 750™ anti-mouse CD3ε 145-2C11 FC
APC/Fire™ 810 anti-mouse CD3ε Antibody 145-2C11 FC
Spark YG™ 581 anti-mouse CD3ε (Flexi-Fluor™) 145-2C11 FC
Spark NIR™ 685 anti-mouse CD3ε (Flexi-Fluor™) Antibody 145-2C11 FC
PE/Fire™ 640 anti-mouse CD3ε 145-2C11
Go To Top Version: 1    Revision Date: 11.30.2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Pricing & Availability
Clone
145-2C11 (See other available formats)
Regulatory Status
RUO
Other Names
CD3ε, T3, CD3
Isotype
Armenian Hamster IgG
Ave. Rating
Submit a Review
Product Citations
publications
145-2C11_FITC_021606
C57BL/6 mouse splenocytes were stained with CD3e (clone 145-2C11) FITC and CD127 (clone SB/199) PE.
  • 145-2C11_FITC_021606
    C57BL/6 mouse splenocytes were stained with CD3e (clone 145-2C11) FITC and CD127 (clone SB/199) PE.
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability Save
100305 50 µg NOK248
Check Availability


Need larger quantities of this item?
Request Bulk Quote
100306 500 µg NOK817
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
H-2Kb-specific mouse cytotoxic T lymphocyte clone BM10-37
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone 145-2C11 is useful for in vitro blocking of target-specific CTL-mediated cell lysis1, as well as T cell activation assays, inducing proliferation and cytokine production1,2,7,12,16. It also induces apoptosis in immature thymocytes32,  and in vivo T cell depletion8-10. Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1, immunohistochemical staining14,15 of acetone-fixed frozen sections and zinc-fixed paraffin-embedded sections, Western blotting4, complement-mediated cytotoxicity6, in vitro and in vivo stimulation of T cells1,2,7,12,16, immunofluorescent staining5, and in vivo T cell depletion8-10. The 145-2C11 antibody has been reported to block the binding of 17A2 antibody to CD3 epsilon-specific T cells11. Clone 145-2C11 is not recommended for formalin-fixed paraffin embedded sections. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 100314). For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 100340) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).

Application References
  1. Leo O, et al. 1987. P. Natl. Acad. Sci. USA 84:1374. (IP, Activ, Block)
  2. Kruisbeek AM, et al. 1991. In Current Protocols in Immunology. 3.12.1. (Activ)
  3. Duke RC, et al. 1995. Current Protocols in Immunology. 3.17.1.
  4. Salvadori S, et al. 1994. J. Immunol. 153:5176. (WB)
  5. Payer E, et al. 1991. J. Immunol. 146:2536. (IF)
  6. Jacobs H, et al. 1994. Eur. J. Immunol. 24:934. (CMCD)
  7. Vossen ACTM, et al. 1995. Eur. J. Immunol. 25:1492. (Activ)
  8. Henrickson M, et al. 1995. Transplantation 60:828. (Deplete)
  9. Kinnaert P, et al. 1996. Transpl. Int. 9:386. (Deplete)
  10. Han WR, et al. 1999. Transpl. Immunol. 7:207. (Deplete)
  11. Miescher GC, et al. 1989. Immunol. Lett. 23:113. (Block)
  12. Terrazas LI, et al. 2005. Intl. J. Parasitology. 35:1349. (Activ)
  13. Ko SY, et al. 2005. J. Immunol. 175:3309.
  14. Podd BS, et al. 2006. J. Immunol. 176:6532. (IHC-F)
  15. Tilley SL, et al. 2007. J. Immunol. 178:3208. (IHC-F)
  16. Wang W, et al. 2007. J. Immunol. 178:4885. (Activ)
  17. Xiao S, et al. 2007. J. Exp. Med. 204:1691.
  18. Chappaz S, et al. 2007. Blood doi:10.1182/blood-2007-02-074245. (FC) PubMed.
  19. Curtsinger JM, et al.2005. J. Immunol. 175:4392. PubMed
  20. Guo Y, et al. 2008. Blood 112:480. PubMed
  21. Kenna TJ, et al. 2008. Blood 111:2091.
  22. Perchonock CE, et al. 2007. J. Immunol. 179:1768. PubMed
  23. Perchonock GE, et al. 2006. Mol. Cell. Biol. 26:6005. PubMed
  24. Kanaya T, et al. 2008. Am. J. Physiol. Gastrointest. Liver Physiol. 295:G273. PubMed
  25. de Koning BA, et al. 2006. Int. Immunol. 18:941. PubMed
  26. Schulteis RD, et al. 2008. Blood 295:G273. PubMed
  27. Qi Q, et al. 2009. Blood 114:564. PubMed
  28. Helmersson S, et al. 2013. Am J Pathol. 9440:123. Pubmed
  29. Wu S, et al. 2014. Clin Vaccine Immunol. 21:156. PubMed
  30. Yan J, et al. 2014. Vaccine. 32:2833. PubMed
  31. Guiterrez DA, et al. 2014. Diaebetes. 63:3827. PubMed
  32. Shi YF, et al. 1991. J Immunol. 146:3340. (Apop)
Product Citations
  1. Chei S, et al. 2020. Front Nutr. 7:583186. PubMed
  2. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  3. Bertrand F, et al. 2017. Nat Commun. 8:2256. PubMed
  4. Katsumura KR, et al. 2018. Proc Natl Acad Sci U S A. 115:E10109. PubMed
  5. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  6. Russler-Germain EV, et al. 2021. Immunity. 54:2547. PubMed
  7. Li DD, et al. 2022. J Cell Mol Med. 26:2438. PubMed
  8. Jou E, et al. 2022. Sci Immunol. 7:eabn0175. PubMed
  9. Zhao X, et al. 2022. STAR Protoc. 3:101859. PubMed
  10. Yang L, et al. 2023. Acta Pharmacol Sin. :. PubMed
  11. Lu T, et al. 2023. Cancer Immunol Immunother. :. PubMed
  12. Smith LA, et al. 2023. Front Oncol. 12:1031174. PubMed
  13. Murakata Y, et al. 2023. Front Cardiovasc Med. 9:1075358. PubMed
  14. Jerome JR, et al. 2023. Int J Mol Sci. 24: . PubMed
  15. Drijvers JM, et al. 2021. Cancer Immunol Res. 9:184. PubMed
  16. Glorieux C, et al. 2022. J Adv Res. 40:109. PubMed
  17. Wu R, et al. 2022. Nat Immunol. 23:1536. PubMed
  18. Lu C, et al. 2023. Antiviral Res. 212:105556. PubMed
  19. Wang JX, et al. 2023. JCI Insight. 8:. PubMed
  20. Wu Y, et al. 2023. Nat Cancer. 4:382. PubMed
  21. Brunner SM, et al. 2023. Int J Mol Sci. 24:. PubMed
  22. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  23. Stitzlein LM, et al. 2023. Front Neurol. 14:1112207. PubMed
  24. van Os BW, et al. 2023. Front Cardiovasc Med. 10:1171764. PubMed
  25. Ye S, et al. 2023. Front Oncol. 13:1202750. PubMed
  26. Lentucci C, et al. 2017. J Biol Chem. 292:2754-2772. PubMed
  27. Schulteis R, et al. 2008. Blood. 112:4905. PubMed
  28. Wang L, et al. 2019. Cell Rep. 29:1848. PubMed
  29. Groza D, et al. 2018. Oncoimmunology. 7:e1424676. PubMed
  30. Zhou J, et al. 2021. Int J Med Sci. 18:3516. PubMed
  31. Fornari T, et al. 2015. PLoS One. 10: 0142688. PubMed
  32. Koning B, et al. 2006. Int Immunol. 1.403472222. PubMed
  33. Hewitson JP, et al. 2020. J Immunol. 204:2949. PubMed
  34. Johnson KD, et al. 2022. Blood Adv. 6:1464. PubMed
  35. Lou F, et al. 2020. STAR Protoc. 1:100115. PubMed
  36. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  37. Gruber T, et al. 2020. JCI Insight. 5:00. PubMed
  38. Allegrezza M, et al. 2016. Cancer Res . 76: 6253 - 6265. PubMed
  39. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  40. Isoda T et al. 2017. Cell. 171(1):103-119 . PubMed
  41. Waide ML, et al. 2020. Cell Rep. 33:108503. PubMed
  42. Kremenovic M, et al. 2022. J Immunother Cancer. 10:. PubMed
  43. Tian H, et al. 2022. Cancer Sci. 113:875. PubMed
  44. Bartleson JM, et al. 2020. Nat Immunol. 1384:21. PubMed
  45. Hung PJ, et al. 2018. Mol Cell. 71:332. PubMed
  46. Patnode M, et al. 2013. Glycobiology. 23:381. PubMed
  47. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
  48. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  49. Yi M, et al. 2021. J Hematol Oncol. 14:27. PubMed
  50. Zhang X, et al. 2020. J Immunol. 205:1743. PubMed
  51. Peng L, et al. 2020. Transl Lung Cancer Res. 0.892361111. PubMed
  52. Best SA, et al. 2018. Cell Metab. 27:935. PubMed
  53. Uchida A, et al. 2021. J Inflamm Res. 14:3089. PubMed
  54. Sato Y, et al. 2021. J Clin Invest. Online ahead of print. PubMed
  55. Pereira JL, et al. 2021. Transl Oncol. 14:101125. PubMed
  56. Collin R, et al. 2014. J Immunol. 193:3503. PubMed
  57. Yin Q, et al. 2015. PLoS One. 10: 0137808. PubMed
  58. Ma Y, et al. 2015. J Immunol. 195: 3769 - 3780. PubMed
  59. Matsumura K, et al. 2016. J Immunol. 197: 3233 - 3244. PubMed
  60. Qi X, et al. 2019. Nat Med. 25:1225. PubMed
  61. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  62. Lin JR et al. 2018. eLife. 7 pii: e31657. PubMed
  63. Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed
  64. Li H, et al. 2022. Theranostics. 12:6422. PubMed
  65. Jeong SH, et al. 2021. Nat Commun. 12:4405. PubMed
  66. Huang Y, et al. 2020. FASEB J. 34:1768. PubMed
  67. Kawakami R, et al. 2021. Immunity. 54(5):947-961.e8. PubMed
  68. Burrack K, et al. 2015. PLoS Pathog. 11: e1005191. PubMed
  69. Skeate JG, et al. 2018. PLoS One. 13:e0191311. PubMed
  70. He L, et al. 2019. iScience. 0.790972222. PubMed
  71. Cheng HW, et al. 2019. Nat Commun. 10:1739. PubMed
  72. Cong J et al. 2018. Cell metabolism. 28(2):243-255 . PubMed
  73. Tang CC, et al. 2021. eLife. 10:00. PubMed
  74. Gong Y, et al. 2020. Cell Metabolism. 33(1):51-64.e9. PubMed
  75. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  76. Souza COS, et al. 2021. iScience. 24(6):102548. PubMed
  77. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  78. Miki Y, et al. 2016. J Biol Chem. 291: 15588 - 15601. PubMed
  79. Knolle MD et al. 2018. Frontiers in immunology. 1.925 . PubMed
  80. Doonan J, et al. 2019. Nat Commun. 10:1554. PubMed
  81. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  82. Russler-Germain EV, et al. 2021. Elife. 10:. PubMed
  83. Pardy RD, et al. 2021. Nat Commun. 12:4051. PubMed
  84. Yang H, et al. 2022. Nutrients. 14:. PubMed
  85. Kondratieva T, et al. 2020. PLoS One. 15:e0239668. PubMed
  86. Ringel AE, et al. 2020. Cell. 183(7):1848-1866.e26. PubMed
  87. Yi X, et al. 2020. Sci Adv. 6:eaba3546. PubMed
  88. Burrack K, et al. 2015. J Immunol. 194:678. PubMed
  89. Siamishi I, et al. 2020. Cell Reports. 31(11):107756. PubMed
  90. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  91. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  92. Stotesbury C, et al. 2020. J Immunol. 204:1582. PubMed
  93. Wanner-Seleznik GM, et al. 2020. Immunohorizons. 0.644444444. PubMed
  94. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  95. Kim SH, et al. 2021. Cell Reports. 35(2):108995. PubMed
  96. Kacherovsky N, et al. 2019. Nat Biomed Eng. 0.66875. PubMed
  97. Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
  98. Murakami K, et al. 2021. Cell Reports. 34(1):108579. PubMed
  99. Ni J, et al. 2020. Immunity. 52(6):1075-1087.e8. PubMed
  100. Bian G, et al. 2020. British Journal of Pharmacology. 178(3):636-653. PubMed
  101. Galle-Treger L, et al. 2016. Nat Commun. 7:13202. PubMed
  102. Sendler M, et al. 2020. Gastroenterology. 158:253. PubMed
  103. Denny JE, et al. 2019. Sci Rep. 2.786111111. PubMed
  104. Kim MY, et al. 2017. Plant Biotechnol J. 1.729166667. PubMed
  105. Huang J, et al. 2014. J Immunol. 192:1972. PubMed
  106. Xu M, et al. 2013. J Immunol. 190:5436. PubMed
  107. Xu Q, et al. 2021. Theranostics. 11:1937. PubMed
  108. Zhang P, et al. 2022. Nat Commun. 13:1588. PubMed
  109. Vacca F, et al. 2020. eLife. 9:e54017.. PubMed
  110. Labiano S, et al. 2017. Oncoimmunology. 6:e1283468. PubMed
  111. Engblom C, et al. 2017. Science. 358:6367. PubMed
  112. Baomei Wang et al. 2019. Cell reports. 26(6):1614-1626 . PubMed
  113. Lind L, et al. 2021. J Neurovirol. 27:145. PubMed
  114. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  115. Eisemann T, et al. 2019. Front Oncol. 9:187. PubMed
  116. Yue W, et al. 2019. Nat Commun. 10:2025. PubMed
  117. Oliveira AC et al. 2017. eLife. 6 pii: e30883. PubMed
  118. Agrawal M, et al. 2022. Blood. 140:1094. PubMed
  119. Zhao X, et al. 2022. iScience. 25:104690. PubMed
  120. Soria-Castro R, et al. 2020. Sci Rep. 10:17802. PubMed
  121. Casselli T, et al. 2021. PLoS Pathog. 17:e1009256. PubMed
  122. Okada R, et al. 2021. EBioMedicine. 67:103345. PubMed
  123. Luo L, et al. 2021. J Neuroinflammation. 18:27. PubMed
  124. Damgaard RB et al. 2016. Cell. 166(5):1215-1230 . PubMed
  125. Baglaenko Y, et al. 2016. PLoS One. 11: 0150515. PubMed
  126. Wang J, et al. 2019. Aging (Albany NY). 11:3463. PubMed
  127. Lin JC, et al. 2019. Nat Commun. 10:1057. PubMed
  128. Liu Y, et al. 2018. Cancer Cell. 33:480. PubMed
  129. Sánchez-del-Campo L, et al. 2021. J Exp Clin Cancer Res. 40:117. PubMed
  130. Okuyama Y, et al. 2020. FASEB J. 540:34. PubMed
  131. La Salvia S, et al. 2020. Am J Physiol Renal Physiol. 319:F868. PubMed
  132. Sparber F, et al. 2019. Cell Host Microbe. 25:389. PubMed
  133. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  134. Fitzpatrick Z, et al. 2020. Nature. 587:472. PubMed
  135. Srivastava S, et al. 2020. Cancer Cell. 39(2):193-208.e10. PubMed
  136. Sheng J, et al. 2021. eLife. 10:00. PubMed
  137. Nakagawa Y, et al. 2015. Immunol Lett. 167: 72-86. PubMed
  138. Ikeda T, et al. 2014. PLoS One. 9:115198. PubMed
  139. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  140. Tippimanchai DD, et al. 2018. Oncoimmunology. 7:e1438105. PubMed
  141. Schofield L, et al. 2017. BMC Med. 10.1186/s12916-017-0883-8. PubMed
  142. Oh J, et al. 2021. Clin Cancer Res. 27:4781. PubMed
  143. Harding CL, et al. 2020. Front Cell Infect Microbiol. 10:328. PubMed
  144. Xiao Z, et al. 2022. Mater Today Bio. 15:100297. PubMed
  145. Ma C, et al. 2021. Mol Metab. 47:101170. PubMed
  146. Tian T, et al. 2020. Cancer Immunol Res. 660:8. PubMed
  147. Zhou X, et al. 2021. Nutr Metab (Lond). 18:64. PubMed
  148. Zhang S, et al. 2016. PLoS Pathog. 12: 1005617. PubMed
  149. L M, et al. 2016. Brain. 139: 1939-1957. PubMed
  150. Krotova K, et al. 2019. Mol Ther Oncolytics. 15:166. PubMed
  151. Lai NY, et al. 2020. Cell. 180:33:00. PubMed
  152. Kanaya T, et al. 2008. Am J Physiol Gastrointest Liver Physiol. 295:273. PubMed
  153. Hilt ZT, et al. 2019. JCI Insight. 4:5. PubMed
  154. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  155. Rivera CA, et al. 2022. Immunity. 55:129. PubMed
  156. Awida Z, et al. 2021. Int J Mol Sci. 23:. PubMed
  157. Amatruda M, et al. 2022. Brain Commun. 4:fcac044. PubMed
  158. Aggarwal N, et al. 2021. Cell Rep. 37:110170. PubMed
  159. Chei S, et al. 2020. Front Nutr. 7:583186. PubMed
  160. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  161. Bertrand F, et al. 2017. Nat Commun. 8:2256. PubMed
  162. Katsumura KR, et al. 2018. Proc Natl Acad Sci U S A. 115:E10109. PubMed
  163. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  164. Russler-Germain EV, et al. 2021. Immunity. 54:2547. PubMed
  165. Li DD, et al. 2022. J Cell Mol Med. 26:2438. PubMed
  166. Jou E, et al. 2022. Sci Immunol. 7:eabn0175. PubMed
  167. Zhao X, et al. 2022. STAR Protoc. 3:101859. PubMed
  168. Yang L, et al. 2023. Acta Pharmacol Sin. :. PubMed
  169. Lu T, et al. 2023. Cancer Immunol Immunother. :. PubMed
  170. Smith LA, et al. 2023. Front Oncol. 12:1031174. PubMed
  171. Murakata Y, et al. 2023. Front Cardiovasc Med. 9:1075358. PubMed
  172. Jerome JR, et al. 2023. Int J Mol Sci. 24: . PubMed
  173. Drijvers JM, et al. 2021. Cancer Immunol Res. 9:184. PubMed
  174. Glorieux C, et al. 2022. J Adv Res. 40:109. PubMed
  175. Wu R, et al. 2022. Nat Immunol. 23:1536. PubMed
  176. Lu C, et al. 2023. Antiviral Res. 212:105556. PubMed
  177. Wang JX, et al. 2023. JCI Insight. 8:. PubMed
  178. Wu Y, et al. 2023. Nat Cancer. 4:382. PubMed
  179. Brunner SM, et al. 2023. Int J Mol Sci. 24:. PubMed
  180. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  181. Stitzlein LM, et al. 2023. Front Neurol. 14:1112207. PubMed
  182. van Os BW, et al. 2023. Front Cardiovasc Med. 10:1171764. PubMed
  183. Ye S, et al. 2023. Front Oncol. 13:1202750. PubMed
  184. Lentucci C, et al. 2017. J Biol Chem. 292:2754-2772. PubMed
  185. Schulteis R, et al. 2008. Blood. 112:4905. PubMed
  186. Wang L, et al. 2019. Cell Rep. 29:1848. PubMed
  187. Groza D, et al. 2018. Oncoimmunology. 7:e1424676. PubMed
  188. Zhou J, et al. 2021. Int J Med Sci. 18:3516. PubMed
  189. Fornari T, et al. 2015. PLoS One. 10: 0142688. PubMed
  190. Koning B, et al. 2006. Int Immunol. 1.403472222. PubMed
  191. Hewitson JP, et al. 2020. J Immunol. 204:2949. PubMed
  192. Johnson KD, et al. 2022. Blood Adv. 6:1464. PubMed
  193. Lou F, et al. 2020. STAR Protoc. 1:100115. PubMed
  194. Delacher M, et al. 2021. Immunity. 54(4):702-720.e17. PubMed
  195. Gruber T, et al. 2020. JCI Insight. 5:00. PubMed
  196. Allegrezza M, et al. 2016. Cancer Res . 76: 6253 - 6265. PubMed
  197. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  198. Isoda T et al. 2017. Cell. 171(1):103-119 . PubMed
  199. Waide ML, et al. 2020. Cell Rep. 33:108503. PubMed
  200. Kremenovic M, et al. 2022. J Immunother Cancer. 10:. PubMed
  201. Tian H, et al. 2022. Cancer Sci. 113:875. PubMed
  202. Bartleson JM, et al. 2020. Nat Immunol. 1384:21. PubMed
  203. Hung PJ, et al. 2018. Mol Cell. 71:332. PubMed
  204. Patnode M, et al. 2013. Glycobiology. 23:381. PubMed
  205. Mann M, et al. 2018. Cell Rep. 25:2992. PubMed
  206. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  207. Yi M, et al. 2021. J Hematol Oncol. 14:27. PubMed
  208. Zhang X, et al. 2020. J Immunol. 205:1743. PubMed
  209. Peng L, et al. 2020. Transl Lung Cancer Res. 0.892361111. PubMed
  210. Best SA, et al. 2018. Cell Metab. 27:935. PubMed
  211. Uchida A, et al. 2021. J Inflamm Res. 14:3089. PubMed
  212. Sato Y, et al. 2021. J Clin Invest. Online ahead of print. PubMed
  213. Pereira JL, et al. 2021. Transl Oncol. 14:101125. PubMed
  214. Collin R, et al. 2014. J Immunol. 193:3503. PubMed
  215. Yin Q, et al. 2015. PLoS One. 10: 0137808. PubMed
  216. Ma Y, et al. 2015. J Immunol. 195: 3769 - 3780. PubMed
  217. Matsumura K, et al. 2016. J Immunol. 197: 3233 - 3244. PubMed
  218. Qi X, et al. 2019. Nat Med. 25:1225. PubMed
  219. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  220. Lin JR et al. 2018. eLife. 7 pii: e31657. PubMed
  221. Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed
  222. Li H, et al. 2022. Theranostics. 12:6422. PubMed
  223. Jeong SH, et al. 2021. Nat Commun. 12:4405. PubMed
  224. Huang Y, et al. 2020. FASEB J. 34:1768. PubMed
  225. Kawakami R, et al. 2021. Immunity. 54(5):947-961.e8. PubMed
  226. Burrack K, et al. 2015. PLoS Pathog. 11: e1005191. PubMed
  227. Skeate JG, et al. 2018. PLoS One. 13:e0191311. PubMed
  228. He L, et al. 2019. iScience. 0.790972222. PubMed
  229. Cheng HW, et al. 2019. Nat Commun. 10:1739. PubMed
  230. Cong J et al. 2018. Cell metabolism. 28(2):243-255 . PubMed
  231. Tang CC, et al. 2021. eLife. 10:00. PubMed
  232. Gong Y, et al. 2020. Cell Metabolism. 33(1):51-64.e9. PubMed
  233. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  234. Souza COS, et al. 2021. iScience. 24(6):102548. PubMed
  235. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  236. Miki Y, et al. 2016. J Biol Chem. 291: 15588 - 15601. PubMed
  237. Knolle MD et al. 2018. Frontiers in immunology. 1.925 . PubMed
  238. Doonan J, et al. 2019. Nat Commun. 10:1554. PubMed
  239. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  240. Russler-Germain EV, et al. 2021. Elife. 10:. PubMed
  241. Pardy RD, et al. 2021. Nat Commun. 12:4051. PubMed
  242. Yang H, et al. 2022. Nutrients. 14:. PubMed
  243. Kondratieva T, et al. 2020. PLoS One. 15:e0239668. PubMed
  244. Ringel AE, et al. 2020. Cell. 183(7):1848-1866.e26. PubMed
  245. Yi X, et al. 2020. Sci Adv. 6:eaba3546. PubMed
  246. Burrack K, et al. 2015. J Immunol. 194:678. PubMed
  247. Siamishi I, et al. 2020. Cell Reports. 31(11):107756. PubMed
  248. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  249. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  250. Stotesbury C, et al. 2020. J Immunol. 204:1582. PubMed
  251. Wanner-Seleznik GM, et al. 2020. Immunohorizons. 0.644444444. PubMed
  252. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  253. Kim SH, et al. 2021. Cell Reports. 35(2):108995. PubMed
  254. Kacherovsky N, et al. 2019. Nat Biomed Eng. 0.66875. PubMed
  255. Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
  256. Murakami K, et al. 2021. Cell Reports. 34(1):108579. PubMed
  257. Ni J, et al. 2020. Immunity. 52(6):1075-1087.e8. PubMed
  258. Bian G, et al. 2020. British Journal of Pharmacology. 178(3):636-653. PubMed
  259. Galle-Treger L, et al. 2016. Nat Commun. 7:13202. PubMed
  260. Sendler M, et al. 2020. Gastroenterology. 158:253. PubMed
  261. Denny JE, et al. 2019. Sci Rep. 2.786111111. PubMed
  262. Kim MY, et al. 2017. Plant Biotechnol J. 1.729166667. PubMed
  263. Huang J, et al. 2014. J Immunol. 192:1972. PubMed
  264. Xu M, et al. 2013. J Immunol. 190:5436. PubMed
  265. Xu Q, et al. 2021. Theranostics. 11:1937. PubMed
  266. Zhang P, et al. 2022. Nat Commun. 13:1588. PubMed
  267. Vacca F, et al. 2020. eLife. 9:e54017.. PubMed
  268. Labiano S, et al. 2017. Oncoimmunology. 6:e1283468. PubMed
  269. Engblom C, et al. 2017. Science. 358:6367. PubMed
  270. Baomei Wang et al. 2019. Cell reports. 26(6):1614-1626 . PubMed
  271. Lind L, et al. 2021. J Neurovirol. 27:145. PubMed
  272. Kang YH, et al. 2019. Nat Commun. 10:912. PubMed
  273. Eisemann T, et al. 2019. Front Oncol. 9:187. PubMed
  274. Yue W, et al. 2019. Nat Commun. 10:2025. PubMed
  275. Oliveira AC et al. 2017. eLife. 6 pii: e30883. PubMed
  276. Agrawal M, et al. 2022. Blood. 140:1094. PubMed
  277. Zhao X, et al. 2022. iScience. 25:104690. PubMed
  278. Soria-Castro R, et al. 2020. Sci Rep. 10:17802. PubMed
  279. Casselli T, et al. 2021. PLoS Pathog. 17:e1009256. PubMed
  280. Okada R, et al. 2021. EBioMedicine. 67:103345. PubMed
  281. Luo L, et al. 2021. J Neuroinflammation. 18:27. PubMed
  282. Damgaard RB et al. 2016. Cell. 166(5):1215-1230 . PubMed
  283. Baglaenko Y, et al. 2016. PLoS One. 11: 0150515. PubMed
  284. Wang J, et al. 2019. Aging (Albany NY). 11:3463. PubMed
  285. Lin JC, et al. 2019. Nat Commun. 10:1057. PubMed
  286. Liu Y, et al. 2018. Cancer Cell. 33:480. PubMed
  287. Sánchez-del-Campo L, et al. 2021. J Exp Clin Cancer Res. 40:117. PubMed
  288. Okuyama Y, et al. 2020. FASEB J. 540:34. PubMed
  289. La Salvia S, et al. 2020. Am J Physiol Renal Physiol. 319:F868. PubMed
  290. Sparber F, et al. 2019. Cell Host Microbe. 25:389. PubMed
  291. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  292. Fitzpatrick Z, et al. 2020. Nature. 587:472. PubMed
  293. Srivastava S, et al. 2020. Cancer Cell. 39(2):193-208.e10. PubMed
  294. Sheng J, et al. 2021. eLife. 10:00. PubMed
  295. Nakagawa Y, et al. 2015. Immunol Lett. 167: 72-86. PubMed
  296. Ikeda T, et al. 2014. PLoS One. 9:115198. PubMed
  297. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  298. Tippimanchai DD, et al. 2018. Oncoimmunology. 7:e1438105. PubMed
  299. Schofield L, et al. 2017. BMC Med. 10.1186/s12916-017-0883-8. PubMed
  300. Oh J, et al. 2021. Clin Cancer Res. 27:4781. PubMed
  301. Harding CL, et al. 2020. Front Cell Infect Microbiol. 10:328. PubMed
  302. Xiao Z, et al. 2022. Mater Today Bio. 15:100297. PubMed
  303. Ma C, et al. 2021. Mol Metab. 47:101170. PubMed
  304. Tian T, et al. 2020. Cancer Immunol Res. 660:8. PubMed
  305. Zhou X, et al. 2021. Nutr Metab (Lond). 18:64. PubMed
  306. Zhang S, et al. 2016. PLoS Pathog. 12: 1005617. PubMed
  307. L M, et al. 2016. Brain. 139: 1939-1957. PubMed
  308. Krotova K, et al. 2019. Mol Ther Oncolytics. 15:166. PubMed
  309. Lai NY, et al. 2020. Cell. 180:33:00. PubMed
  310. Kanaya T, et al. 2008. Am J Physiol Gastrointest Liver Physiol. 295:273. PubMed
  311. Hilt ZT, et al. 2019. JCI Insight. 4:5. PubMed
  312. Guo Y, et al. 2021. Nat Immunol. 22:746. PubMed
  313. Rivera CA, et al. 2022. Immunity. 55:129. PubMed
  314. Awida Z, et al. 2021. Int J Mol Sci. 23:. PubMed
  315. Amatruda M, et al. 2022. Brain Commun. 4:fcac044. PubMed
  316. Aggarwal N, et al. 2021. Cell Rep. 37:110170. PubMed
RRID
AB_312670 (BioLegend Cat. No. 100305)
AB_312671 (BioLegend Cat. No. 100306)

Antigen Details

Structure
Ig superfamily, forms CD3/TCR complex with CD3δ, γ and ζ subunits and TCR (α/β and γ/δ), 20 kD
Distribution

Thymocytes (differentiation dependent), mature T cells, NK-T cells

Function
TCR signal transduction, T cell activation, antigen recognition
Ligand/Receptor
Peptide antigen/MHC-complex
Cell Type
NKT cells, T cells, Thymocytes, Tregs
Biology Area
Immunology
Molecular Family
CD Molecules, TCRs
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Davis MM. 1990. Annu. Rev. Biochem. 59:475.
3. Weiss A, et al. 1994. Cell 76:263.

Gene ID
12501 View all products for this Gene ID
UniProt
View information about CD3epsilon on UniProt.org

Other Formats

View All CD3ε Reagents Request Custom Conjugation
Description Clone Applications
PE/Cyanine7 anti-mouse CD3ε 145-2C11 FC
Purified anti-mouse CD3ε (Maxpar® Ready) 145-2C11 FC,CyTOF®
PE/Dazzle™ 594 anti-mouse CD3ε 145-2C11 FC
Brilliant Violet 510™ anti-mouse CD3ε 145-2C11 FC
Brilliant Violet 605™ anti-mouse CD3ε 145-2C11 FC
Brilliant Violet 711™ anti-mouse CD3ε 145-2C11 FC
Brilliant Violet 785™ anti-mouse CD3ε 145-2C11 FC
APC/Fire™ 750 anti-mouse CD3ε 145-2C11 FC
GoInVivo™ Purified anti-mouse CD3ε 145-2C11 FC
APC anti-mouse CD3ε 145-2C11 FC
Biotin anti-mouse CD3ε 145-2C11 FC,IHC-F
FITC anti-mouse CD3ε 145-2C11 FC
PE anti-mouse CD3ε 145-2C11 FC
PE/Cyanine5 anti-mouse CD3ε 145-2C11 FC
Purified anti-mouse CD3ε 145-2C11 FC,IHC-F,IP,Activ,Block,WB,ICC
Alexa Fluor® 488 anti-mouse CD3ε 145-2C11 FC
Alexa Fluor® 647 anti-mouse CD3ε 145-2C11 FC,IHC-F,3D IHC
PerCP anti-mouse CD3ε 145-2C11 FC
PerCP/Cyanine5.5 anti-mouse CD3ε 145-2C11 FC
APC/Cyanine7 anti-mouse CD3ε 145-2C11 FC
Pacific Blue™ anti-mouse CD3ε 145-2C11 FC
Brilliant Violet 421™ anti-mouse CD3ε 145-2C11 FC,ICC
Ultra-LEAF™ Purified anti-mouse CD3ε 145-2C11 FC,IHC-F,IP,Activ,Block,WB,ICC
Spark YG™ 593 anti-mouse CD3 145-2C11 FC
PerCP/Fire™ 780 anti-mouse CD3ε 145-2C11 FC
Brilliant Violet 650™ anti-mouse CD3ε 145-2C11 FC
Brilliant Violet 750™ anti-mouse CD3ε 145-2C11 FC
APC/Fire™ 810 anti-mouse CD3ε Antibody 145-2C11 FC
Spark YG™ 581 anti-mouse CD3ε (Flexi-Fluor™) 145-2C11 FC
Spark NIR™ 685 anti-mouse CD3ε (Flexi-Fluor™) Antibody 145-2C11 FC
PE/Fire™ 640 anti-mouse CD3ε 145-2C11
Go To Top Version: 1    Revision Date: 11.30.2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account