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PE anti-mouse CD3 Antibody PE anti-mouse CD3 Antibody

Pricing & Availability
Clone
17A2 (See other available formats)
Regulatory Status
RUO
Other Names
T cell antigen receptor complex, T3
Isotype
Rat IgG2b, κ
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Product Citations
publications
17A2_PE_021606
C57BL/6 mouse splenocytes stained with 17A2 PE
  • 17A2_PE_021606
    C57BL/6 mouse splenocytes stained with 17A2 PE
Compare all formats See PE spectral data
Cat # Size Price Quantity Check Availability Save
100206 200 µg NOK1180
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100205 50 µg NOK504
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Description

CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
γδTCR-positive T-T hybridoma D1
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported application (for relevant formats) include: spatial biology (IBEX)1,2.

Application References
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  2. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
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  186. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
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  209. Ma C, et al. 2018. Science. 360:eaan5931. PubMed
  210. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  211. Kuang Z, et al. 2020. Antib Ther. 3:227. PubMed
  212. Hu D, et al. 2021. J Cell Mol Med. 25:2900. PubMed
  213. Mathur S, et al. 2021. JCI Insight. 6:. PubMed
  214. Ohyagi M, et al. 2021. Nat Commun. 12:7344. PubMed
  215. Yan X, et al. 2022. Int J Biol Sci. 18:585. PubMed
  216. Helm M, et al. 2022. Life (Basel). 12:. PubMed
  217. Tu X, et al. 2022. Nat Commun. 13:6977. PubMed
  218. Vannini N, et al. 2019. Cell Stem Cell. 24:405. PubMed
  219. Biram A, et al. 2020. Cell Rep. 30:1910. PubMed
  220. Delgado‐Benito V et al. 2018. Molecular cell. 72(4):636-649 . PubMed
  221. Mariani SA, et al. 2019. Immunity. 50:1439. PubMed
  222. Stutchfield B, et al. 2015. Gastroenterology. 149: 1896-1909.e14. PubMed
  223. Koren N, et al. 2021. Cell Host Microbe. 29(2):197-209.e5. PubMed
  224. Stivala S, et al. 2019. J Clin Invest. 130:1596. PubMed
  225. Zhang D, et al. 2020. Signal Transduct Target Ther. 5:24. PubMed
  226. Wang F, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:257. PubMed
  227. Zhou Y, et al. 2022. Nat Commun. 13:2906. PubMed
  228. Wu J, et al. 2020. Immunity. 53:115. PubMed
  229. Domingos-Pereira S, et al. 2019. Cancer Immunol Res. 7:621. PubMed
  230. Lin H, et al. 2019. Infect Immun. 87:e00055-19. PubMed
  231. Pedraza–Zamora CP, et al. 2017. Parasite Immunol. 39:4. PubMed
  232. McAlpine CS, et al. 2021. Nature. 595:701. PubMed
  233. Wu L, et al. 2022. Theranostics. 12:842. PubMed
  234. Goldman E, et al. 2021. Cells. 10:. PubMed
  235. Cassidy BR, et al. 2020. J Neuroinflammation. 17:259. PubMed
  236. Chen Y, et al. 2015. PLoS One. 10: 0135217. PubMed
  237. Li Y, et al. 2020. Cell Stem Cell. 27(5):732-747.e7. PubMed
  238. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  239. Doonan J, et al. 2019. Nat Commun. 10:1554. PubMed
  240. Halpern KB, et al. 2018. Nat Biotechnol. 36:962. PubMed
  241. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  242. Paul S, et al. 2018. Appl Microbiol Biotechnol. 102:8895. PubMed
  243. Marinescu CI, et al. 2021. Stem Cell Res Ther. 12:319. PubMed
  244. Shi R, et al. 2022. Theranostics. 12:875. PubMed
  245. Cheng B, et al. 2022. Cancer Commun (Lond). 42:17. PubMed
  246. Glaros V, et al. 2021. Immunity. 54:2005. PubMed
  247. Hu J, et al. 2022. J Neuroinflammation. 19:71. PubMed
  248. O'Connor T, et al. 2020. Cancer Cell. 36(3):250-267. PubMed
  249. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  250. Chauveau A, et al. 2020. Immunity. 52:794. PubMed
  251. Mishra BB, et al. 2017. Nat Microbiol. 2:17072. PubMed
  252. Kim JH, et al. 2019. Mol Med. 25:33. PubMed
  253. Pedraza-Zamora C, et al. 2017. Parasite Immunol. 10.1111/pim.12420. PubMed
  254. Fang E, et al. 2022. MedComm (2020). 3:e117. PubMed
  255. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  256. Zuo S, et al. 2021. J Immunother Cancer. 9:. PubMed
  257. Lewandowski JP, et al. 2020. Genome Biol. 1.039583333. PubMed
  258. Kruta M, et al. 2021. Cell Stem Cell. :. PubMed
  259. Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
  260. Huang Z, et al. 2021. Nat Commun. 12:145. PubMed
  261. Cho K, et al. 2021. iScience. 24:103117. PubMed
  262. Zhou Z, et al. 2022. Infect Immun. 90:e0045321. PubMed
  263. Bullard BL, et al. 2022. NPJ Vaccines. 7:65. PubMed
  264. Tomala J, et al. 2020. Methods Mol Biol. 2111:101. PubMed
  265. Nikolos F, et al. 2022. Nat Commun. 13:1487. PubMed
  266. Rozanski C, et al. 2015. J Immunol. 194:4717. PubMed
  267. Zou D, et al. 2020. EBioMedicine. 52:102652. PubMed
  268. Sanmarco LM, et al. 2021. Nature. 590:473. PubMed
  269. Fang H, et al. 2020. Nat Commun. 4.661805556. PubMed
  270. Tummers B, et al. 2020. Immunity. 52(6):994-1006.e8. PubMed
  271. Sun J et al. 2018. Cell stem cell. 23(3):355-369 . PubMed
  272. Huang L, et al. 2018. Exp Neurol. 300:41. PubMed
  273. Ding Y, et al. 2020. Evid Based Complement Alternat Med. 2020:9521073. PubMed
  274. Zhang T, et al. 2020. Cell. 180(6):1115-1129. PubMed
  275. Gamrekelashvili J, et al. 2021. Bio Protoc. 11:e4007. PubMed
  276. Feng Y, et al. 2022. J Nanobiotechnology. 20:193. PubMed
  277. Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
  278. Cai Z, et al. 2020. Cell Rep. 31:107816. PubMed
  279. Yamamura K, et al. 2017. Nat Commun. 8:13946. PubMed
  280. Hsieh Y, et al. 2014. Infect Immun . 82:2087. PubMed
  281. Winchell CG, et al. 2020. Front Immunol. 1.077083333. PubMed
  282. Chan WY, et al. 2019. Infect Immun. 87:. PubMed
  283. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  284. Olson B, et al. 2021. Brain Behav Immun. 97:102. PubMed
  285. Schneider A, et al. 2014. J Leukoc Biol. 96:857. PubMed
  286. Yao C, et al. 2018. Autophagy. 1.854861111. PubMed
  287. Zhang MS, et al. 2022. Nat Commun. 13:954. PubMed
  288. Jazowiecka-Rakus J, et al. 2020. Mol Ther Oncolytics. 18:335. PubMed
  289. Chen H, et al. 2022. Front Pharmacol. 13:827520. PubMed
  290. Zhou T, et al. 2021. Bioact Mater. 0.734027778. PubMed
  291. Kim MY, et al. 2022. Nat Commun. 13:3296. PubMed
  292. Zhou H, et al. 2021. Cell Death Discov. 7:332. PubMed
  293. Zhang D, et al. 2020. Signal Transduct Target Ther. 5:24. PubMed
  294. Lu C, et al. 2020. Cancer Cell. 39(1):96-108.e6. PubMed
  295. Uluçkan ö, et al. 2020. Cell Reports. 29(4):844-859.e3.. PubMed
  296. Rodríguez L, et al. 2021. Biomolecules. 11: . PubMed
  297. Maulhardt HA, et al. 2020. Invest New Drugs. 1618:38. PubMed
  298. Yu H, et al. 2015. PLoS One. 10: 0143001. PubMed
  299. Fathman J, et al. 2010. Proc Natl Acad Sci U S A. 107:3663. PubMed
  300. Hidalgo San Jose L, et al. 2020. Cell Rep. 30:69. PubMed
  301. Gundra UM, et al. 2017. Nat Immunol. 1.195833333. PubMed
  302. Sun Y, et al. 2022. iScience. 25:104846. PubMed
  303. Vannini N, et al. 2016. Nat Commun. 7:13125. PubMed
  304. Wu L, et al. 2020. Cancer Immunol Res. 710:8. PubMed
  305. Das A, et al. 2020. J Bone Miner Res. 36:199. PubMed
  306. Crowe J, et al. 2020. PLoS Pathog. 16:e1008391. PubMed
  307. Gawish R, et al. 2022. Elife. 11:. PubMed
  308. Zeng F, et al. 2021. J Invest Dermatol. 596:141. PubMed
  309. Guo S, et al. 2021. Frontiers in Immunology. 11:614667. PubMed
  310. Xiang W, et al. 2020. Signal Transduct Target Ther. 0.374305556. PubMed
  311. Hayashi K, et al. 2020. Nat Commun. 4.832638889. PubMed
  312. He C, et al. 2021. Immunol Cell Biol. 99:611. PubMed
  313. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  314. Zuo S, et al. 2021. EBioMedicine. 64:103240. PubMed
RRID
AB_312663 (BioLegend Cat. No. 100206)
AB_312662 (BioLegend Cat. No. 100205)

Antigen Details

Structure
Ig superfamily, CD3/TCR, 20 kD
Distribution

Thymocytes (differentiation dependent), mature T cells, NK-T cells

Function
Antigen recognition, TCR signal transduction, T cell activation
Ligand/Receptor
Peptide antigen/MHC-complex
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Davis MM. 1990. Annu. Rev. Biochem. 59:475.
3. Weiss A, et al. 1994. Cell 76:263.

Gene ID
12502 View all products for this Gene ID
UniProt
View information about CD3 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.

Other Formats

View All CD3 Reagents Request Custom Conjugation
Description Clone Applications
Brilliant Violet 711™ anti-mouse CD3 17A2 FC
Biotin anti-mouse CD3 17A2 FC,IHC-F
PE/Dazzle™ 594 anti-mouse CD3 17A2 FC
APC/Fire™ 750 anti-mouse CD3 17A2 FC
Brilliant Violet 750™ anti-mouse CD3 17A2 FC
TotalSeq™-A0182 anti-mouse CD3 17A2 PG
TotalSeq™-B0182 anti-mouse CD3 17A2 PG
Spark Blue™ 550 anti-mouse CD3 17A2 FC
Spark NIR™ 685 anti-mouse CD3 17A2 FC
TotalSeq™-C0182 anti-mouse CD3 17A2 PG
APC/Fire™ 810 anti-mouse CD3 17A2 FC
PE/Fire™ 640 anti-mouse CD3 17A2 FC
PE/Fire™ 700 anti-mouse CD3 17A2 FC
Spark YG™ 570 anti-mouse CD3 17A2 IHC-F
FITC anti-mouse CD3 17A2 FC
PE anti-mouse CD3 17A2 FC
Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Test 17A2 5 17A2
Alexa Fluor® 488 anti-mouse CD3 17A2 FC,IHC-F,3D IHC
Alexa Fluor® 647 anti-mouse CD3 17A2 FC,IHC-F,3D IHC,SB
Pacific Blue™ anti-mouse CD3 17A2 FC
Alexa Fluor® 700 anti-mouse CD3 17A2 FC
PE/Cyanine7 anti-mouse CD3 17A2 FC
PerCP/Cyanine5.5 anti-mouse CD3 17A2 FC
APC/Cyanine7 anti-mouse CD3 17A2 FC
Brilliant Violet 421™ anti-mouse CD3 17A2 FC,ICC
Brilliant Violet 570™ anti-mouse CD3 17A2 FC
Brilliant Violet 650™ anti-mouse CD3 17A2 FC
Brilliant Violet 785™ anti-mouse CD3 17A2 FC
Brilliant Violet 510™ anti-mouse CD3 17A2 FC
APC anti-mouse CD3 17A2 FC
Ultra-LEAF™ Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Brilliant Violet 605™ anti-mouse CD3 17A2 FC
Alexa Fluor® 594 anti-mouse CD3 17A2 IHC-F,FC,3D IHC,SB
PE/Cyanine5 anti-mouse CD3 17A2 FC
Spark Blue™ 574 anti-mouse CD3 Antibody 17A2 FC
Spark Violet™ 423 anti-mouse CD3 17A2 FC
PE/Fire™ 810 anti-mouse CD3 17A2 FC
Spark Red™ 718 anti-mouse CD3 17A2 FC
Spark UV™ 387 anti-mouse CD3 17A2 FC
PerCP anti-mouse CD3 Antibody 17A2 FC
PerCP/Fire™ 780 anti-mouse CD3 Antibody 17A2 FC
Spark YG™ 581 anti-mouse CD3 (Flexi-Fluor™) 17A2 FC
Spark YG™ 593 anti-mouse CD3 (Flexi-Fluor™) Antibody 17A2 FC
Spark PLUS B488™ anti-mouse CD3 17A2 FC
Go To Top Version: 1    Revision Date: 11.30.2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Pricing & Availability
Clone
17A2 (See other available formats)
Regulatory Status
RUO
Other Names
T cell antigen receptor complex, T3
Isotype
Rat IgG2b, κ
Ave. Rating
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Product Citations
publications
17A2_PE_021606
C57BL/6 mouse splenocytes stained with 17A2 PE
  • 17A2_PE_021606
    C57BL/6 mouse splenocytes stained with 17A2 PE
Compare all formats See PE spectral data
Cat # Size Price Quantity Check Availability Save
100206 200 µg NOK1180
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100205 50 µg NOK504
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Description

CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
γδTCR-positive T-T hybridoma D1
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported application (for relevant formats) include: spatial biology (IBEX)1,2.

Application References
  1. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  2. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
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  2. Zhao L, et al. 2022. Oncogene. 41:4200. PubMed
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  6. Sun JY, et al. 2023. Sci Adv. 9:eade4110. PubMed
  7. Shi Y, et al. 2023. Nat Commun. 14:1884. PubMed
  8. Fiedler T, et al. 2023. J Neuroinflammation. 20:100. PubMed
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  12. Milighetti M, et al. 2023. iScience. 26:106937. PubMed
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  14. Xue G, et al. 2021. Cancer Cell. 39:1610. PubMed
  15. Hiyoshi H, et al. 2022. Cell Host Microbe. 30:163. PubMed
  16. Chan WY, et al. 2022. Infect Immun. 90:e0084618a. PubMed
  17. Wang D, et al. 2022. Cell Rep. 39:110587. PubMed
  18. Mirchandani AS, et al. 2022. Nat Immunol. 23:927. PubMed
  19. Yang K, et al. 2022. Sci Immunol. 7:eabn2888. PubMed
  20. McAlpine CS, et al. 2022. J Exp Med. 219: . PubMed
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  26. Giannou AD, et al. 2023. Immunity. 56:125. PubMed
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  37. Li Q, et al. 2022. Cell Rep. 40:111308. PubMed
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  41. Bedi B, et al. 2012. Proc Natl Acad Sci U S A. 109:275. PubMed
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  43. Liang W, et al. 2020. Nat Commun. 4.563888889. PubMed
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  45. Periasamy S, et al. 2017. Nat Commun. 8:15564. PubMed
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  140. Maulhardt HA, et al. 2020. Invest New Drugs. 1618:38. PubMed
  141. Yu H, et al. 2015. PLoS One. 10: 0143001. PubMed
  142. Fathman J, et al. 2010. Proc Natl Acad Sci U S A. 107:3663. PubMed
  143. Hidalgo San Jose L, et al. 2020. Cell Rep. 30:69. PubMed
  144. Gundra UM, et al. 2017. Nat Immunol. 1.195833333. PubMed
  145. Sun Y, et al. 2022. iScience. 25:104846. PubMed
  146. Vannini N, et al. 2016. Nat Commun. 7:13125. PubMed
  147. Wu L, et al. 2020. Cancer Immunol Res. 710:8. PubMed
  148. Das A, et al. 2020. J Bone Miner Res. 36:199. PubMed
  149. Crowe J, et al. 2020. PLoS Pathog. 16:e1008391. PubMed
  150. Gawish R, et al. 2022. Elife. 11:. PubMed
  151. Zeng F, et al. 2021. J Invest Dermatol. 596:141. PubMed
  152. Guo S, et al. 2021. Frontiers in Immunology. 11:614667. PubMed
  153. Xiang W, et al. 2020. Signal Transduct Target Ther. 0.374305556. PubMed
  154. Hayashi K, et al. 2020. Nat Commun. 4.832638889. PubMed
  155. He C, et al. 2021. Immunol Cell Biol. 99:611. PubMed
  156. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  157. Zuo S, et al. 2021. EBioMedicine. 64:103240. PubMed
  158. Zuchtriegel G, et al. 2016. PLoS Biol. 14: 1002459. PubMed
  159. Zhao L, et al. 2022. Oncogene. 41:4200. PubMed
  160. Guo D, et al. 2023. Cell Biosci. 13:51. PubMed
  161. Fan NW, et al. 2023. FASEB J. 37:e22855. PubMed
  162. Zhang X, et al. 2023. Front Immunol. 14:1116749. PubMed
  163. Sun JY, et al. 2023. Sci Adv. 9:eade4110. PubMed
  164. Shi Y, et al. 2023. Nat Commun. 14:1884. PubMed
  165. Fiedler T, et al. 2023. J Neuroinflammation. 20:100. PubMed
  166. Li Y, et al. 2023. Front Cell Infect Microbiol. 13:1117230. PubMed
  167. Bhaskar A, et al. 2023. iScience. 26:106644. PubMed
  168. Wang Y, et al. 2023. iScience. 26:106630. PubMed
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  170. Xu C, et al. 2017. Biochemical and Biophysical Research Communications. 10.1016/j.bbrc.2017.05.071. PubMed
  171. Xue G, et al. 2021. Cancer Cell. 39:1610. PubMed
  172. Hiyoshi H, et al. 2022. Cell Host Microbe. 30:163. PubMed
  173. Chan WY, et al. 2022. Infect Immun. 90:e0084618a. PubMed
  174. Wang D, et al. 2022. Cell Rep. 39:110587. PubMed
  175. Mirchandani AS, et al. 2022. Nat Immunol. 23:927. PubMed
  176. Yang K, et al. 2022. Sci Immunol. 7:eabn2888. PubMed
  177. McAlpine CS, et al. 2022. J Exp Med. 219: . PubMed
  178. TaSli PN, et al. 2022. J Food Biochem. 46:e14393. PubMed
  179. Shen Z, et al. 2022. EBioMedicine. 85:104285. PubMed
  180. Deng P, et al. 2022. J Clin Invest. 132: . PubMed
  181. Wei M, et al. 2022. Front Immunol. 13:1017574. PubMed
  182. Domingos-Pereira S, et al. 2022. Int J Mol Sci. 24: . PubMed
  183. Giannou AD, et al. 2023. Immunity. 56:125. PubMed
  184. Briukhovetska D, et al. 2023. Immunity. 56:143. PubMed
  185. Meacham CE, et al. 2022. Nat Cell Biol. 24:697. PubMed
  186. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
  187. Gonalves S, et al. 2021. Cell Reports. 34(11):108860. PubMed
  188. Reboldi A, et al. 2016. Sci Transl Med. 352: aaf4822. PubMed
  189. Gazit R, et al. 2014. J Exp Med. 211:1315. PubMed
  190. Baryawno N et al. 2019. Cell. 177(7):1915-1932 . PubMed
  191. Shen S, et al. 2018. Pain Med. 19:686. PubMed
  192. Ushijima M, et al. 2018. Front Immunol. 9:243. PubMed
  193. Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
  194. Li Q, et al. 2022. Cell Rep. 40:111308. PubMed
  195. Jong RM, et al. 2022. J Immunol. 208:407. PubMed
  196. Baptista AP et al. 2019. Immunity. 50(5):1188-1201 . PubMed
  197. Kunimura K, et al. 2020. Cell Reports. 29(9):2823-2834.e7.. PubMed
  198. Bedi B, et al. 2012. Proc Natl Acad Sci U S A. 109:275. PubMed
  199. Xu ZH, et al. 2021. Mediators Inflamm. 2021:8856326. PubMed
  200. Liang W, et al. 2020. Nat Commun. 4.563888889. PubMed
  201. Lutzmann M, et al. 2019. Cell Rep. 28:2851. PubMed
  202. Periasamy S, et al. 2017. Nat Commun. 8:15564. PubMed
  203. Lechner AJ et al. 2017. Cell stem cell. 21(1):120-134 . PubMed
  204. Shu T, et al. 2022. Eur Respir J. Online ahead of print. PubMed
  205. Al-Rifai R, et al. 2022. Nat Commun. 13:6592. PubMed
  206. Jazowiecka-Rakus J, et al. 2021. Cancers (Basel). 13:. PubMed
  207. Schmidt D, et al. 2016. PLoS One. 11: 0159059. PubMed
  208. He C, et al. 2020. Clin Transl Med. 10:e39. PubMed
  209. Ma C, et al. 2018. Science. 360:eaan5931. PubMed
  210. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  211. Kuang Z, et al. 2020. Antib Ther. 3:227. PubMed
  212. Hu D, et al. 2021. J Cell Mol Med. 25:2900. PubMed
  213. Mathur S, et al. 2021. JCI Insight. 6:. PubMed
  214. Ohyagi M, et al. 2021. Nat Commun. 12:7344. PubMed
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RRID
AB_312663 (BioLegend Cat. No. 100206)
AB_312662 (BioLegend Cat. No. 100205)

Antigen Details

Structure
Ig superfamily, CD3/TCR, 20 kD
Distribution

Thymocytes (differentiation dependent), mature T cells, NK-T cells

Function
Antigen recognition, TCR signal transduction, T cell activation
Ligand/Receptor
Peptide antigen/MHC-complex
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Davis MM. 1990. Annu. Rev. Biochem. 59:475.
3. Weiss A, et al. 1994. Cell 76:263.

Gene ID
12502 View all products for this Gene ID
UniProt
View information about CD3 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.

Other Formats

View All CD3 Reagents Request Custom Conjugation
Description Clone Applications
Brilliant Violet 711™ anti-mouse CD3 17A2 FC
Biotin anti-mouse CD3 17A2 FC,IHC-F
PE/Dazzle™ 594 anti-mouse CD3 17A2 FC
APC/Fire™ 750 anti-mouse CD3 17A2 FC
Brilliant Violet 750™ anti-mouse CD3 17A2 FC
TotalSeq™-A0182 anti-mouse CD3 17A2 PG
TotalSeq™-B0182 anti-mouse CD3 17A2 PG
Spark Blue™ 550 anti-mouse CD3 17A2 FC
Spark NIR™ 685 anti-mouse CD3 17A2 FC
TotalSeq™-C0182 anti-mouse CD3 17A2 PG
APC/Fire™ 810 anti-mouse CD3 17A2 FC
PE/Fire™ 640 anti-mouse CD3 17A2 FC
PE/Fire™ 700 anti-mouse CD3 17A2 FC
Spark YG™ 570 anti-mouse CD3 17A2 IHC-F
FITC anti-mouse CD3 17A2 FC
PE anti-mouse CD3 17A2 FC
Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Test 17A2 5 17A2
Alexa Fluor® 488 anti-mouse CD3 17A2 FC,IHC-F,3D IHC
Alexa Fluor® 647 anti-mouse CD3 17A2 FC,IHC-F,3D IHC,SB
Pacific Blue™ anti-mouse CD3 17A2 FC
Alexa Fluor® 700 anti-mouse CD3 17A2 FC
PE/Cyanine7 anti-mouse CD3 17A2 FC
PerCP/Cyanine5.5 anti-mouse CD3 17A2 FC
APC/Cyanine7 anti-mouse CD3 17A2 FC
Brilliant Violet 421™ anti-mouse CD3 17A2 FC,ICC
Brilliant Violet 570™ anti-mouse CD3 17A2 FC
Brilliant Violet 650™ anti-mouse CD3 17A2 FC
Brilliant Violet 785™ anti-mouse CD3 17A2 FC
Brilliant Violet 510™ anti-mouse CD3 17A2 FC
APC anti-mouse CD3 17A2 FC
Ultra-LEAF™ Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Brilliant Violet 605™ anti-mouse CD3 17A2 FC
Alexa Fluor® 594 anti-mouse CD3 17A2 IHC-F,FC,3D IHC,SB
PE/Cyanine5 anti-mouse CD3 17A2 FC
Spark Blue™ 574 anti-mouse CD3 Antibody 17A2 FC
Spark Violet™ 423 anti-mouse CD3 17A2 FC
PE/Fire™ 810 anti-mouse CD3 17A2 FC
Spark Red™ 718 anti-mouse CD3 17A2 FC
Spark UV™ 387 anti-mouse CD3 17A2 FC
PerCP anti-mouse CD3 Antibody 17A2 FC
PerCP/Fire™ 780 anti-mouse CD3 Antibody 17A2 FC
Spark YG™ 581 anti-mouse CD3 (Flexi-Fluor™) 17A2 FC
Spark YG™ 593 anti-mouse CD3 (Flexi-Fluor™) Antibody 17A2 FC
Spark PLUS B488™ anti-mouse CD3 17A2 FC
Go To Top Version: 1    Revision Date: 11.30.2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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