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APC Anti-mouse TCR γ/δ Antibody APC Anti-mouse TCR γ/δ Antibody

Pricing & Availability
Clone
GL3 (See other available formats)
Regulatory Status
RUO
Other Names
T cell receptor γ/δ
Isotype
Armenian Hamster IgG
Ave. Rating
Submit a Review
Product Citations
publications
A_GL3_APC_083109
C57BL/6 mouse lymph node cells stained with CD3 (145-2C11) PE and GL-3 APC
  • A_GL3_APC_083109
    C57BL/6 mouse lymph node cells stained with CD3 (145-2C11) PE and GL-3 APC
  • B_GL3_APC_083109.jpg
    C57BL/6 mouse lymph node cells stained with CD3 (145-2C11) PE and Armenian hamster IgG APC isotype control
Compare all formats See APC spectral data
Cat # Size Price Quantity Check Availability Save
118116 100 µg SEK1395
Check Availability


Need larger quantities of this item?
Request Bulk Quote
118115 25 µg SEK857
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, which is involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. γ/δ TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8- although some are CD8+. T cells expressing the γ/δ TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
C57BL/6J intraepithelial lymphocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

The GL3 antibody has been shown to be useful in identifying γ/δ T cells by flow cytometry and immunohistochemistry and depleting γ/δ T cells in vivo. Additional reported applications (for the relevant formats) include: immunoprecipitation1, immunohistochemistry of acetone-fixed frozen sections2,6, and in vivo depletion of γ/δ T cells3-5.

Application References
  1. Goodman T, et al. 1989. J. Exp. Med. 170:1569. (FC, IP)
  2. Cardona AE, et al. 2003. Infect. Immun. 71:2634. (IHC)
  3. Kapp JA, et al. 2004. Immunology 111:155. (Deplete)
  4. Skelsey ME, et al. 2001. J. Immunol. 166:4327. (Deplete)
  5. Ke Y, et al. 1997. J. Immunol. 158:3610. (Deplete)
  6. Podd BS, et al. 2006. J. Immunol. 176:6532. (IHC)
  7. Kasten KR, et al. 2010. Infect. Immun. 78:4714. (FC) PubMed
  8. Stadanlick JE, et al. 2011. J. Immunol. 187:664. PubMed
  9. Van Belle AB, et al. 2012. J. Immunol. 188:462. PubMed
Product Citations
  1. Ge Y, et al. 2022. iScience. 25:105437. PubMed
  2. Peng Q, et al. 2023. EMBO Rep. 24:e56034. PubMed
  3. Giannou AD, et al. 2023. Immunity. 56:125. PubMed
  4. Elliot TAE, et al. 2022. Discov Immunol. 1:kyac009. PubMed
  5. Wang Y, et al. 2023. iScience. 26:106630. PubMed
  6. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  7. Heindl S, et al. 2021. J Exp Med. 218:. PubMed
  8. Willcox CR, et al. 2020. Immunity. 51(5):813-825.e4.. PubMed
  9. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  10. Park JH, et al. 2022. STAR Protoc. 3:101607. PubMed
  11. Tan L, et al. 2019. Cell Rep. 27:3657. PubMed
  12. Pokrovskii M, et al. 2020. EMBO J. 39:e104159. PubMed
  13. Liu X, et al. 2020. Nature. . PubMed
  14. Han Y et al. 2019. Cell reports. 27(3):835-846 . PubMed
  15. Liu X, et al. 2021. eLife. 0.416666666666667. PubMed
  16. Zhan Y, et al. 2021. JCI Insight. 6:. PubMed
  17. Wang Z, et al. 2020. Autophagy. 1:. PubMed
  18. Mantri CK, et al. 2019. J Clin Invest. 129:1094. PubMed
  19. Sophie Thiemann et al. 2017. Cell host & microbe. 21(6):682-694 . PubMed
  20. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  21. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  22. Varol D et al. 2017. Immunity. 46(6):1030-1044 . PubMed
  23. Shook BA, et al. 2020. Cell Stem Cell. 26(6):880-895. PubMed
  24. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  25. Hrdinka M, et al. 2016. PLoS One. 11: 0162863. PubMed
  26. Cai Y, et al. 2019. Cell Rep. 27:3034. PubMed
  27. Duan H, et al. 2021. J Clin Invest. 131:. PubMed
  28. Pandit M, et al. 2021. Eur J Immunol. 51:1461. PubMed
  29. Guo Y, et al. 2013. Infect Immun . 81:3923. PubMed
  30. Baomei Wang et al. 2019. Cell reports. 26(6):1614-1626 . PubMed
  31. Sakamoto K, et al. 2021. Immunity. 54:2321. PubMed
  32. Li J, et al. 2020. Development. :. PubMed
  33. Zhang X, et al. 2021. Front Pharmacol. 12:629513. PubMed
  34. Liang Q, et al. 2020. Front Microbiol. 11:571847. PubMed
  35. Zeis P, et al. 2020. Immunity. 53:775. PubMed
  36. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  37. Pai M, et al. 2016. JPEN J Parenter Enteral Nutr. 40: 383 - 391. PubMed
  38. Amezcua Vesely MC, et al. 2020. Cell. 178(5):1176-1188.e15.. PubMed
  39. Bajaña S, et al. 2022. iScience. 25:103732. PubMed
  40. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  41. Hackstein CP, et al. 2022. Nat Commun. 13:7472. PubMed
  42. Wang X, et al. 2022. Elife. 11:. PubMed
  43. Pelly V, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.4. PubMed
  44. Wunderlich CM, et al. 2018. Nat Commun. 9:1646. PubMed
  45. Zhang S, et al. 2016. PLoS Pathog. 12: 1005617. PubMed
  46. Corrado M, et al. 2020. Cell Metab. 32:981. PubMed
  47. Huang LH et al. 2018. Cell metabolism. 29(2):475-487 . PubMed
  48. Moriyasu T, et al. 2018. PLoS Negl Trop Dis. 12:e0006197. PubMed
  49. Hester AK, et al. 2022. Cell Rep. 38:110363. PubMed
  50. Ge Y, et al. 2022. iScience. 25:105437. PubMed
  51. Peng Q, et al. 2023. EMBO Rep. 24:e56034. PubMed
  52. Giannou AD, et al. 2023. Immunity. 56:125. PubMed
  53. Elliot TAE, et al. 2022. Discov Immunol. 1:kyac009. PubMed
  54. Wang Y, et al. 2023. iScience. 26:106630. PubMed
  55. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  56. Heindl S, et al. 2021. J Exp Med. 218:. PubMed
  57. Willcox CR, et al. 2020. Immunity. 51(5):813-825.e4.. PubMed
  58. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  59. Park JH, et al. 2022. STAR Protoc. 3:101607. PubMed
  60. Tan L, et al. 2019. Cell Rep. 27:3657. PubMed
  61. Pokrovskii M, et al. 2020. EMBO J. 39:e104159. PubMed
  62. Liu X, et al. 2020. Nature. . PubMed
  63. Han Y et al. 2019. Cell reports. 27(3):835-846 . PubMed
  64. Liu X, et al. 2021. eLife. 0.416666666666667. PubMed
  65. Zhan Y, et al. 2021. JCI Insight. 6:. PubMed
  66. Wang Z, et al. 2020. Autophagy. 1:. PubMed
  67. Mantri CK, et al. 2019. J Clin Invest. 129:1094. PubMed
  68. Sophie Thiemann et al. 2017. Cell host & microbe. 21(6):682-694 . PubMed
  69. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  70. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  71. Varol D et al. 2017. Immunity. 46(6):1030-1044 . PubMed
  72. Shook BA, et al. 2020. Cell Stem Cell. 26(6):880-895. PubMed
  73. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  74. Hrdinka M, et al. 2016. PLoS One. 11: 0162863. PubMed
  75. Cai Y, et al. 2019. Cell Rep. 27:3034. PubMed
  76. Duan H, et al. 2021. J Clin Invest. 131:. PubMed
  77. Pandit M, et al. 2021. Eur J Immunol. 51:1461. PubMed
  78. Guo Y, et al. 2013. Infect Immun . 81:3923. PubMed
  79. Baomei Wang et al. 2019. Cell reports. 26(6):1614-1626 . PubMed
  80. Sakamoto K, et al. 2021. Immunity. 54:2321. PubMed
  81. Li J, et al. 2020. Development. :. PubMed
  82. Zhang X, et al. 2021. Front Pharmacol. 12:629513. PubMed
  83. Liang Q, et al. 2020. Front Microbiol. 11:571847. PubMed
  84. Zeis P, et al. 2020. Immunity. 53:775. PubMed
  85. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  86. Pai M, et al. 2016. JPEN J Parenter Enteral Nutr. 40: 383 - 391. PubMed
  87. Amezcua Vesely MC, et al. 2020. Cell. 178(5):1176-1188.e15.. PubMed
  88. Bajaña S, et al. 2022. iScience. 25:103732. PubMed
  89. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  90. Hackstein CP, et al. 2022. Nat Commun. 13:7472. PubMed
  91. Wang X, et al. 2022. Elife. 11:. PubMed
  92. Pelly V, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.4. PubMed
  93. Wunderlich CM, et al. 2018. Nat Commun. 9:1646. PubMed
  94. Zhang S, et al. 2016. PLoS Pathog. 12: 1005617. PubMed
  95. Corrado M, et al. 2020. Cell Metab. 32:981. PubMed
  96. Huang LH et al. 2018. Cell metabolism. 29(2):475-487 . PubMed
  97. Moriyasu T, et al. 2018. PLoS Negl Trop Dis. 12:e0006197. PubMed
  98. Hester AK, et al. 2022. Cell Rep. 38:110363. PubMed
RRID
AB_1731813 (BioLegend Cat. No. 118116)
AB_1731824 (BioLegend Cat. No. 118115)

Antigen Details

Structure
Ig superfamily, associates with CD3 complex.
Distribution

T cell subset in thymus, intestinal epithelium, peripheral lymphoid tissues and peritoneum, most γ/δ T cells are CD4-/CD8-, some are CD8+.

Function
Antigen recognition; γ/δ T cells are thought to play a role in tolerance.
Ligand/Receptor
Some bacterial or tumor antigens bound to MHC class I.
Cell Type
Epithelial cells, T cells, Tregs
Biology Area
Adaptive Immunity, Immunology
Molecular Family
TCRs
Antigen References
  1. Skarstein K, et al. 1995. Immunology. 81:497.
  2. Harrison LC, et al. 1996. J Exp Med. 184:2167.
  3. Wildner G, et al. 1996. Eur J Immunol. 26:2140.
  4. Brandes M, et al. 2005. Science. 309:264.
Gene ID
110066 View all products for this Gene ID 110067 View all products for this Gene ID
UniProt
View information about TCR gamma/delta on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11-30-2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Pricing & Availability
Clone
GL3 (See other available formats)
Regulatory Status
RUO
Other Names
T cell receptor γ/δ
Isotype
Armenian Hamster IgG
Ave. Rating
Submit a Review
Product Citations
publications
A_GL3_APC_083109
C57BL/6 mouse lymph node cells stained with CD3 (145-2C11) PE and GL-3 APC
  • A_GL3_APC_083109
    C57BL/6 mouse lymph node cells stained with CD3 (145-2C11) PE and GL-3 APC
  • B_GL3_APC_083109.jpg
    C57BL/6 mouse lymph node cells stained with CD3 (145-2C11) PE and Armenian hamster IgG APC isotype control
Compare all formats See APC spectral data
Cat # Size Price Quantity Check Availability Save
118116 100 µg SEK1395
Check Availability


Need larger quantities of this item?
Request Bulk Quote
118115 25 µg SEK857
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, which is involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. γ/δ TCR associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8- although some are CD8+. T cells expressing the γ/δ TCR have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
C57BL/6J intraepithelial lymphocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

The GL3 antibody has been shown to be useful in identifying γ/δ T cells by flow cytometry and immunohistochemistry and depleting γ/δ T cells in vivo. Additional reported applications (for the relevant formats) include: immunoprecipitation1, immunohistochemistry of acetone-fixed frozen sections2,6, and in vivo depletion of γ/δ T cells3-5.

Application References
  1. Goodman T, et al. 1989. J. Exp. Med. 170:1569. (FC, IP)
  2. Cardona AE, et al. 2003. Infect. Immun. 71:2634. (IHC)
  3. Kapp JA, et al. 2004. Immunology 111:155. (Deplete)
  4. Skelsey ME, et al. 2001. J. Immunol. 166:4327. (Deplete)
  5. Ke Y, et al. 1997. J. Immunol. 158:3610. (Deplete)
  6. Podd BS, et al. 2006. J. Immunol. 176:6532. (IHC)
  7. Kasten KR, et al. 2010. Infect. Immun. 78:4714. (FC) PubMed
  8. Stadanlick JE, et al. 2011. J. Immunol. 187:664. PubMed
  9. Van Belle AB, et al. 2012. J. Immunol. 188:462. PubMed
Product Citations
  1. Ge Y, et al. 2022. iScience. 25:105437. PubMed
  2. Peng Q, et al. 2023. EMBO Rep. 24:e56034. PubMed
  3. Giannou AD, et al. 2023. Immunity. 56:125. PubMed
  4. Elliot TAE, et al. 2022. Discov Immunol. 1:kyac009. PubMed
  5. Wang Y, et al. 2023. iScience. 26:106630. PubMed
  6. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  7. Heindl S, et al. 2021. J Exp Med. 218:. PubMed
  8. Willcox CR, et al. 2020. Immunity. 51(5):813-825.e4.. PubMed
  9. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  10. Park JH, et al. 2022. STAR Protoc. 3:101607. PubMed
  11. Tan L, et al. 2019. Cell Rep. 27:3657. PubMed
  12. Pokrovskii M, et al. 2020. EMBO J. 39:e104159. PubMed
  13. Liu X, et al. 2020. Nature. . PubMed
  14. Han Y et al. 2019. Cell reports. 27(3):835-846 . PubMed
  15. Liu X, et al. 2021. eLife. 0.416666666666667. PubMed
  16. Zhan Y, et al. 2021. JCI Insight. 6:. PubMed
  17. Wang Z, et al. 2020. Autophagy. 1:. PubMed
  18. Mantri CK, et al. 2019. J Clin Invest. 129:1094. PubMed
  19. Sophie Thiemann et al. 2017. Cell host & microbe. 21(6):682-694 . PubMed
  20. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  21. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  22. Varol D et al. 2017. Immunity. 46(6):1030-1044 . PubMed
  23. Shook BA, et al. 2020. Cell Stem Cell. 26(6):880-895. PubMed
  24. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  25. Hrdinka M, et al. 2016. PLoS One. 11: 0162863. PubMed
  26. Cai Y, et al. 2019. Cell Rep. 27:3034. PubMed
  27. Duan H, et al. 2021. J Clin Invest. 131:. PubMed
  28. Pandit M, et al. 2021. Eur J Immunol. 51:1461. PubMed
  29. Guo Y, et al. 2013. Infect Immun . 81:3923. PubMed
  30. Baomei Wang et al. 2019. Cell reports. 26(6):1614-1626 . PubMed
  31. Sakamoto K, et al. 2021. Immunity. 54:2321. PubMed
  32. Li J, et al. 2020. Development. :. PubMed
  33. Zhang X, et al. 2021. Front Pharmacol. 12:629513. PubMed
  34. Liang Q, et al. 2020. Front Microbiol. 11:571847. PubMed
  35. Zeis P, et al. 2020. Immunity. 53:775. PubMed
  36. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  37. Pai M, et al. 2016. JPEN J Parenter Enteral Nutr. 40: 383 - 391. PubMed
  38. Amezcua Vesely MC, et al. 2020. Cell. 178(5):1176-1188.e15.. PubMed
  39. Bajaña S, et al. 2022. iScience. 25:103732. PubMed
  40. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  41. Hackstein CP, et al. 2022. Nat Commun. 13:7472. PubMed
  42. Wang X, et al. 2022. Elife. 11:. PubMed
  43. Pelly V, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.4. PubMed
  44. Wunderlich CM, et al. 2018. Nat Commun. 9:1646. PubMed
  45. Zhang S, et al. 2016. PLoS Pathog. 12: 1005617. PubMed
  46. Corrado M, et al. 2020. Cell Metab. 32:981. PubMed
  47. Huang LH et al. 2018. Cell metabolism. 29(2):475-487 . PubMed
  48. Moriyasu T, et al. 2018. PLoS Negl Trop Dis. 12:e0006197. PubMed
  49. Hester AK, et al. 2022. Cell Rep. 38:110363. PubMed
  50. Ge Y, et al. 2022. iScience. 25:105437. PubMed
  51. Peng Q, et al. 2023. EMBO Rep. 24:e56034. PubMed
  52. Giannou AD, et al. 2023. Immunity. 56:125. PubMed
  53. Elliot TAE, et al. 2022. Discov Immunol. 1:kyac009. PubMed
  54. Wang Y, et al. 2023. iScience. 26:106630. PubMed
  55. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  56. Heindl S, et al. 2021. J Exp Med. 218:. PubMed
  57. Willcox CR, et al. 2020. Immunity. 51(5):813-825.e4.. PubMed
  58. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  59. Park JH, et al. 2022. STAR Protoc. 3:101607. PubMed
  60. Tan L, et al. 2019. Cell Rep. 27:3657. PubMed
  61. Pokrovskii M, et al. 2020. EMBO J. 39:e104159. PubMed
  62. Liu X, et al. 2020. Nature. . PubMed
  63. Han Y et al. 2019. Cell reports. 27(3):835-846 . PubMed
  64. Liu X, et al. 2021. eLife. 0.416666666666667. PubMed
  65. Zhan Y, et al. 2021. JCI Insight. 6:. PubMed
  66. Wang Z, et al. 2020. Autophagy. 1:. PubMed
  67. Mantri CK, et al. 2019. J Clin Invest. 129:1094. PubMed
  68. Sophie Thiemann et al. 2017. Cell host & microbe. 21(6):682-694 . PubMed
  69. Almeida AS, et al. 2021. Bio Protoc. 11:e4012. PubMed
  70. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  71. Varol D et al. 2017. Immunity. 46(6):1030-1044 . PubMed
  72. Shook BA, et al. 2020. Cell Stem Cell. 26(6):880-895. PubMed
  73. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  74. Hrdinka M, et al. 2016. PLoS One. 11: 0162863. PubMed
  75. Cai Y, et al. 2019. Cell Rep. 27:3034. PubMed
  76. Duan H, et al. 2021. J Clin Invest. 131:. PubMed
  77. Pandit M, et al. 2021. Eur J Immunol. 51:1461. PubMed
  78. Guo Y, et al. 2013. Infect Immun . 81:3923. PubMed
  79. Baomei Wang et al. 2019. Cell reports. 26(6):1614-1626 . PubMed
  80. Sakamoto K, et al. 2021. Immunity. 54:2321. PubMed
  81. Li J, et al. 2020. Development. :. PubMed
  82. Zhang X, et al. 2021. Front Pharmacol. 12:629513. PubMed
  83. Liang Q, et al. 2020. Front Microbiol. 11:571847. PubMed
  84. Zeis P, et al. 2020. Immunity. 53:775. PubMed
  85. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  86. Pai M, et al. 2016. JPEN J Parenter Enteral Nutr. 40: 383 - 391. PubMed
  87. Amezcua Vesely MC, et al. 2020. Cell. 178(5):1176-1188.e15.. PubMed
  88. Bajaña S, et al. 2022. iScience. 25:103732. PubMed
  89. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  90. Hackstein CP, et al. 2022. Nat Commun. 13:7472. PubMed
  91. Wang X, et al. 2022. Elife. 11:. PubMed
  92. Pelly V, et al. 2016. Mucosal Immunol. 10.1038/mi.2016.4. PubMed
  93. Wunderlich CM, et al. 2018. Nat Commun. 9:1646. PubMed
  94. Zhang S, et al. 2016. PLoS Pathog. 12: 1005617. PubMed
  95. Corrado M, et al. 2020. Cell Metab. 32:981. PubMed
  96. Huang LH et al. 2018. Cell metabolism. 29(2):475-487 . PubMed
  97. Moriyasu T, et al. 2018. PLoS Negl Trop Dis. 12:e0006197. PubMed
  98. Hester AK, et al. 2022. Cell Rep. 38:110363. PubMed
RRID
AB_1731813 (BioLegend Cat. No. 118116)
AB_1731824 (BioLegend Cat. No. 118115)

Antigen Details

Structure
Ig superfamily, associates with CD3 complex.
Distribution

T cell subset in thymus, intestinal epithelium, peripheral lymphoid tissues and peritoneum, most γ/δ T cells are CD4-/CD8-, some are CD8+.

Function
Antigen recognition; γ/δ T cells are thought to play a role in tolerance.
Ligand/Receptor
Some bacterial or tumor antigens bound to MHC class I.
Cell Type
Epithelial cells, T cells, Tregs
Biology Area
Adaptive Immunity, Immunology
Molecular Family
TCRs
Antigen References
  1. Skarstein K, et al. 1995. Immunology. 81:497.
  2. Harrison LC, et al. 1996. J Exp Med. 184:2167.
  3. Wildner G, et al. 1996. Eur J Immunol. 26:2140.
  4. Brandes M, et al. 2005. Science. 309:264.
Gene ID
110066 View all products for this Gene ID 110067 View all products for this Gene ID
UniProt
View information about TCR gamma/delta on UniProt.org
Go To Top Version: 1    Revision Date: 11-30-2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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