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FITC anti-mouse/human CD45R/B220 Antibody FITC anti-mouse/human CD45R/B220 Antibody

Pricing & Availability
Clone
RA3-6B2 (See other available formats)
Regulatory Status
RUO
Other Names
B220
Isotype
Rat IgG2a, κ
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Product Citations
publications
RA3-6B2_FITC
C57BL/6 mouse splenocytes stained with RA3-6B2 FITC
  • RA3-6B2_FITC
    C57BL/6 mouse splenocytes stained with RA3-6B2 FITC
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability Save
103205 50 µg SEK252
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103206 500 µg SEK882
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Description

CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human
Reported Reactivity
Cat
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Abelson murine leukemia virus-induced pre-B tumor cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone RA3-6B2 has been described to react with an epitope on the extracellular domain of the transmembrane CD45 glycoprotein which is dependent upon the expression of exon A and specific carbohydrate residues. Additional reported applications (for the relevant formats) include: immunoprecipitation1, in vitro and in vivo modulation of B cell responses2-4, immunohistochemistry of acetone-fixed frozen sections and formalin-fixed paraffin-embedded sections5,6, and spatial biology (IBEX)14,15.

Application References
  1. Coffman RL. 1982. Immunol. Rev. 69:5. (IP)
  2. George A, et al. 1994. J. Immunol. 152:1014. (Activ)
  3. Asensi V, et al. 1989. Immunology 68:204. (Activ)
  4. Domiati-Saad R, et al. 1993. J. Immunol. 151:5936. (Activ)
  5. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  6. Monteith CE, et al. 1996. Can. J. Vet. Res. 60:193. (IHC)
  7. Shih FF, et al. 2006. J. Immunol. 176:3438. (FC)
  8. Chang C L-T, et al. 2007. J. Immunol. 178:6984.
  9. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  10. Lang GL, et al. 2008. Blood 111:2158. PubMed
  11. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  12. del Rio ML, et al. 2011. Transpl. Int. 24:501. (FC) PubMed
  13. Murakami R, et al. 2013. PLoS One. 8:73270. PubMed
  14. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  15. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Katsumura KR, et al. 2018. Proc Natl Acad Sci U S A. 115:E10109. PubMed
  2. Zimmerman SM, et al. 2022. Oncogene. 41:4983. PubMed
  3. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  4. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  5. Wang Z, et al. 2023. Mediators Inflamm. 2023:9810733. PubMed
  6. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  7. Zhao J, et al. 2021. Emerg Microbes Infect. 10:913. PubMed
  8. Hutter K, et al. 2022. Front Immunol. 13:967914. PubMed
  9. Aimaitijiang A, et al. 2022. Genes Cells. 27:25. PubMed
  10. Wang B, et al. 2022. EMBO J. 41:e108946. PubMed
  11. Corral D, et al. 2022. Cell Rep. 39:110715. PubMed
  12. Xu J, et al. 2022. Invest Ophthalmol Vis Sci. 63:15. PubMed
  13. Tatsumi N, et al. 2022. STAR Protoc. 3:101845. PubMed
  14. Meacham CE, et al. 2022. Nat Cell Biol. 24:697. PubMed
  15. Bruggemann TR, et al. 2022. iScience. 25:105185. PubMed
  16. Lunardi A, et al. 2015. Cancer Discovery. 5:550. PubMed
  17. Zaman R, et al. 2021. Immunity. :. PubMed
  18. Wu N, et al. 2020. Cell Rep. 30:1129. PubMed
  19. Schönberger K, et al. 2022. Cell Stem Cell. 29:131. PubMed
  20. Zhang R, et al. 2021. Cell Mol Immunol. 18:1222. PubMed
  21. Israelow B, et al. 2020. bioRxiv. . PubMed
  22. Furuta Y, et al. 2017. PLoS One. 12(2):e0172509. PubMed
  23. Hata E, et al. 2016. Int Immunol. 28: 283 - 292. PubMed
  24. Engel O, et al. 2015. Stroke. 46: 3232 - 3240. PubMed
  25. Kaku H, et al. 2014. J Immunol. 193:5904. PubMed
  26. Stewart I et al. 2018. Immunity. 49(3):477-489 . PubMed
  27. Kim CJ, et al. 2018. Immunity. 49:1034. PubMed
  28. Kelly L, et al. 2011. J Immunol. 187:3026. PubMed
  29. Hewitson JP, et al. 2020. J Immunol. 204:2949. PubMed
  30. Johnson KD, et al. 2022. Blood Adv. 6:1464. PubMed
  31. Chen X, et al. 2021. Theranostics. 11:4655. PubMed
  32. Ota T, et al. 2013. J Immunol. 191:3179. PubMed
  33. Xia S, et al. 2014. J Leukoc Biol. 95:733. PubMed
  34. Tan X, et al. 2016. PLoS One. 11: 0160985. PubMed
  35. Bao H, et al. 2020. Mol Med Rep. 4.675. PubMed
  36. Dong L, et al. 2021. Cancer Cell. . PubMed
  37. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  38. Yang X, et al. 2020. Blood Sci. 2:89. PubMed
  39. Ma C, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  40. Zhu X, et al. 2017. Arch Oral Biol. 10.1016/j.archoralbio.2017.03.010. PubMed
  41. Jones M, et al. 2016. PLoS One. 11: 0157271. PubMed
  42. Wang X, et al. 2016. PLoS Pathog. 12: 1005367. PubMed
  43. Ohyagi M, et al. 2021. Nat Commun. 12:7344. PubMed
  44. Xu F, et al. 2022. Cell Death Discov. 8:142. PubMed
  45. Tu X, et al. 2022. Nat Commun. 13:6977. PubMed
  46. Carbonneau C, et al. 2012. Blood. 119:717. PubMed
  47. Luff DH, et al. 2021. Front Immunol. 631271:12. PubMed
  48. Delgado‐Benito V et al. 2018. Molecular cell. 72(4):636-649 . PubMed
  49. Zanotti KJ, et al. 2019. J Immunol. 202:1573. PubMed
  50. Mariani SA, et al. 2019. Immunity. 50:1439. PubMed
  51. Dey A et al. 2019. The EMBO journal. 38(7) pii: e100293. PubMed
  52. Huang L, et al. 2017. PLoS Biol.. 10.1371/journal.pbio.2001750. PubMed
  53. Dai B, et al. 2022. Theranostics. 12:7603. PubMed
  54. Tanaka Y, et al. 2021. Int J Mol Sci. 22:. PubMed
  55. Fujikura D, et al. 2013. PLoS One. 8:e55321. PubMed
  56. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  57. Qi X, et al. 2019. Nat Med. 25:1225. PubMed
  58. Nakata T, et al. 2020. Proc Natl Acad Sci U S A. 117:28930. PubMed
  59. Yang K, et al. 2022. J Clin Invest. 132:. PubMed
  60. Jing L, et al. 2022. Front Immunol. 13:864995. PubMed
  61. Wang Z, et al. 2021. J Virol. 95:e0141421. PubMed
  62. Zhang X, et al. 2021. Front Immunol. 12:680068. PubMed
  63. Ma Y, et al. 2015. J Immunol. 195: 3769 - 3780. PubMed
  64. Wong R, et al. 2020. Immunity. 53(5):1078-1094.e7. PubMed
  65. Park HB, et al. 2020. Oncoimmunology. 9:1772663. PubMed
  66. Wang GZ, et al. 2019. Nat Commun. 10:1125. PubMed
  67. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  68. Zhang L, et al. 2021. Methods Mol Biol. 2388:175. PubMed
  69. Yang L, et al. 2021. Cell Death Differ. 28:2616. PubMed
  70. Nabar NR, et al. 2022. Autophagy. 18:204. PubMed
  71. Zhang B, et al. 2021. Nat Biomed Eng. 5:1288. PubMed
  72. Köchl R, et al. 2020. Elife. 9:00. PubMed
  73. Pang D, et al. 2015. Clin Transl Immunology. 4: e41. PubMed
  74. Greenwald AC, et al. 2019. J Exp Med. 216:215. PubMed
  75. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  76. Paul S, et al. 2018. Appl Microbiol Biotechnol. 102:8895. PubMed
  77. Marinescu CI, et al. 2021. Stem Cell Res Ther. 12:319. PubMed
  78. Zhu Y, et al. 2022. Clin Transl Med. 12:e887. PubMed
  79. Lu X, et al. 2016. Nat Commun. 7: 12719. PubMed
  80. Hrdinka M, et al. 2016. PLoS One. 11: 0162863. PubMed
  81. Li Y, et al. 2020. Cell Stem Cell. 27(5):732-747.e7. PubMed
  82. DeVito NC, et al. 2021. Cell Reports. 35(5):109071. PubMed
  83. Noah AC, et al. 2020. J Appl Physiol (1985). 473:128. PubMed
  84. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  85. Hutter K, et al. 2020. FEBS J. . PubMed
  86. Siamishi I, et al. 2020. Cell Reports. 31(11):107756. PubMed
  87. St Clair JB, et al. 2017. PLoS One. 12:e0170556. PubMed
  88. Roy K, et al. 2019. Immunity. 50:616. PubMed
  89. Garo LP, et al. 2019. Cell Rep. 28:3353. PubMed
  90. Reismann D, et al. 2017. Nat Commun.. 10.1038/s41467-017-01538-9. PubMed
  91. Chen X, et al. 2021. Cell Rep. 37:109991. PubMed
  92. Elahi S, et al. 2020. Stem Cell Res. 43:101710. PubMed
  93. Zhang YN, et al. 2020. EBioMedicine. 56:102819. PubMed
  94. Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
  95. Zhang H, et al. 2019. Mol Cell. 76:110. PubMed
  96. Li H, et al. 2020. Nature. 584:274. PubMed
  97. Gu X, et al. 2022. Vaccines (Basel). 10:. PubMed
  98. Ku C, et al. 2015. Genes Dev. 29: 1930-1941. PubMed
  99. Lim CX, et al. 2020. Cell Rep. 3793:30. PubMed
  100. Jamali A, et al. 2020. Cell Reports. 32(9):108099. PubMed
  101. Wittner J, et al. 2022. Mucosal Immunol. 15:668. PubMed
  102. Kang X, et al. 2022. J Immunol Res. 2022:8118577. PubMed
  103. Kondo M, et al. 2016. J Immunol. 196: 563 - 572. PubMed
  104. Hayashi K, et al. 2015. Int Immunol. 27: 435-445. PubMed
  105. Morrison V, et al. 2015. J Immunol. 195: 105 - 115. PubMed
  106. Liu R, et al. 2018. Front Immunol. 9:592. PubMed
  107. Nowlan B, et al. 2019. Haematologica. 105:71. PubMed
  108. Morelli AE, et al. 2020. Cell Rep. 30:3448. PubMed
  109. Zhang W, et al. 2020. Nat Commun. 11:1187. PubMed
  110. Liu J, et al. 2021. Immun Inflamm Dis. 9:299. PubMed
  111. Liu R, et al. 2021. Mol Cell Biol. 41:e0025121. PubMed
  112. Chen C, et al. 2021. J Virol. 95:e0082921. PubMed
  113. Chen RJ, et al. 2022. iScience. 25:105595. PubMed
  114. Georgoudaki A, et al. 2016. Cell Rep. 15: 2000-2011. PubMed
  115. Baomei Wang et al. 2019. Cell reports. 26(6):1614-1626 . PubMed
  116. Weng TY, et al. 2018. Sci Rep. 8:8216. PubMed
  117. Zhang C, et al. 2021. J Virol. 95:e0079021. PubMed
  118. Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
  119. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  120. Hsieh Y, et al. 2014. Infect Immun . 82:2087. PubMed
  121. Schuler F, et al. 2017. Nat Commun. . 10.1038/s41467-017-01850-4. PubMed
  122. Laban H, et al. 2018. J Cell Biol. 217:1503. PubMed
  123. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  124. Raju S, et al. 2020. Cell Reports. 29(9):2556-2564.e3.. PubMed
  125. Sanchez HN, et al. 2020. Nat Commun. 0.5. PubMed
  126. Nguyen HTT, et al. 2021. PLoS Pathog. 17:e1010026. PubMed
  127. Soria-Castro R, et al. 2020. Sci Rep. 10:17802. PubMed
  128. Al-Barwani F, et al. 2014. PLoS One. 9:104523. PubMed
  129. Younes AI, et al. 2021. Transl Oncol. 14:100983. PubMed
  130. Kobia FM, et al. 2020. PLoS Biol. 18:e3000850. PubMed
  131. Ghezraoui H, et al. 2018. Nature. 560:122. PubMed
  132. Tian D, et al. 2019. Nat Commun. 10:4246. PubMed
  133. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  134. Zheng Y, et al. 2022. J Immunol. 208:501. PubMed
  135. Golan K et al. 2018. Cell stem cell. 23(4):572-585 . PubMed
  136. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  137. Velazquez VM, et al. 2017. Mol Ther Methods Clin Dev. 0.277083333. PubMed
  138. Ota T, et al. 2011. J Exp Med. 208:617. PubMed
  139. Tsyklauri O, et al. 2021. EMBO Rep. 22:e50785. PubMed
  140. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  141. Hoechst B, et al. 2016. J Immunol. 195:1517-1523. PubMed
  142. Wu Y, et al. 2015. J Immunol. 195: 2612-2623. PubMed
  143. Takahashi T, et al. 2017. J Exp Med. 10.1084/jem.20160247. PubMed
  144. Li K, et al. 2020. Nat Commun. 4.844444444. PubMed
  145. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  146. Nakamura K, et al. 2018. Cancer Cell. 33:634. PubMed
  147. Pan J, et al. 2022. Front Immunol. 13:812924. PubMed
  148. Srivastava S, et al. 2020. Cancer Cell. 39(2):193-208.e10. PubMed
  149. Iwanami N, et al. 2020. iScience. 23:101260. PubMed
  150. Rossnagl S, et al. 2016. PLoS Biol. 14: 1002562. PubMed
  151. Ioanna E Galani et al. 2017. Immunity. 46(5):875-890 . PubMed
  152. Jing Y, et al. 2019. J Allergy Clin Immunol. 144:1377. PubMed
  153. Awida Z, et al. 2021. Int J Mol Sci. 23:. PubMed
  154. Tham SM, et al. 2021. Biomedicines. 9:. PubMed
  155. Uematsu T, et al. 2015. Sci Rep. 5: 17577. PubMed
  156. Katsumura KR, et al. 2018. Proc Natl Acad Sci U S A. 115:E10109. PubMed
  157. Zimmerman SM, et al. 2022. Oncogene. 41:4983. PubMed
  158. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  159. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  160. Wang Z, et al. 2023. Mediators Inflamm. 2023:9810733. PubMed
  161. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  162. Zhao J, et al. 2021. Emerg Microbes Infect. 10:913. PubMed
  163. Hutter K, et al. 2022. Front Immunol. 13:967914. PubMed
  164. Aimaitijiang A, et al. 2022. Genes Cells. 27:25. PubMed
  165. Wang B, et al. 2022. EMBO J. 41:e108946. PubMed
  166. Corral D, et al. 2022. Cell Rep. 39:110715. PubMed
  167. Xu J, et al. 2022. Invest Ophthalmol Vis Sci. 63:15. PubMed
  168. Tatsumi N, et al. 2022. STAR Protoc. 3:101845. PubMed
  169. Meacham CE, et al. 2022. Nat Cell Biol. 24:697. PubMed
  170. Bruggemann TR, et al. 2022. iScience. 25:105185. PubMed
  171. Lunardi A, et al. 2015. Cancer Discovery. 5:550. PubMed
  172. Zaman R, et al. 2021. Immunity. :. PubMed
  173. Wu N, et al. 2020. Cell Rep. 30:1129. PubMed
  174. Schönberger K, et al. 2022. Cell Stem Cell. 29:131. PubMed
  175. Zhang R, et al. 2021. Cell Mol Immunol. 18:1222. PubMed
  176. Israelow B, et al. 2020. bioRxiv. . PubMed
  177. Furuta Y, et al. 2017. PLoS One. 12(2):e0172509. PubMed
  178. Hata E, et al. 2016. Int Immunol. 28: 283 - 292. PubMed
  179. Engel O, et al. 2015. Stroke. 46: 3232 - 3240. PubMed
  180. Kaku H, et al. 2014. J Immunol. 193:5904. PubMed
  181. Stewart I et al. 2018. Immunity. 49(3):477-489 . PubMed
  182. Kim CJ, et al. 2018. Immunity. 49:1034. PubMed
  183. Kelly L, et al. 2011. J Immunol. 187:3026. PubMed
  184. Hewitson JP, et al. 2020. J Immunol. 204:2949. PubMed
  185. Johnson KD, et al. 2022. Blood Adv. 6:1464. PubMed
  186. Chen X, et al. 2021. Theranostics. 11:4655. PubMed
  187. Ota T, et al. 2013. J Immunol. 191:3179. PubMed
  188. Xia S, et al. 2014. J Leukoc Biol. 95:733. PubMed
  189. Tan X, et al. 2016. PLoS One. 11: 0160985. PubMed
  190. Bao H, et al. 2020. Mol Med Rep. 4.675. PubMed
  191. Dong L, et al. 2021. Cancer Cell. . PubMed
  192. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  193. Yang X, et al. 2020. Blood Sci. 2:89. PubMed
  194. Ma C, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  195. Zhu X, et al. 2017. Arch Oral Biol. 10.1016/j.archoralbio.2017.03.010. PubMed
  196. Jones M, et al. 2016. PLoS One. 11: 0157271. PubMed
  197. Wang X, et al. 2016. PLoS Pathog. 12: 1005367. PubMed
  198. Ohyagi M, et al. 2021. Nat Commun. 12:7344. PubMed
  199. Xu F, et al. 2022. Cell Death Discov. 8:142. PubMed
  200. Tu X, et al. 2022. Nat Commun. 13:6977. PubMed
  201. Carbonneau C, et al. 2012. Blood. 119:717. PubMed
  202. Luff DH, et al. 2021. Front Immunol. 631271:12. PubMed
  203. Delgado‐Benito V et al. 2018. Molecular cell. 72(4):636-649 . PubMed
  204. Zanotti KJ, et al. 2019. J Immunol. 202:1573. PubMed
  205. Mariani SA, et al. 2019. Immunity. 50:1439. PubMed
  206. Dey A et al. 2019. The EMBO journal. 38(7) pii: e100293. PubMed
  207. Huang L, et al. 2017. PLoS Biol.. 10.1371/journal.pbio.2001750. PubMed
  208. Dai B, et al. 2022. Theranostics. 12:7603. PubMed
  209. Tanaka Y, et al. 2021. Int J Mol Sci. 22:. PubMed
  210. Fujikura D, et al. 2013. PLoS One. 8:e55321. PubMed
  211. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  212. Qi X, et al. 2019. Nat Med. 25:1225. PubMed
  213. Nakata T, et al. 2020. Proc Natl Acad Sci U S A. 117:28930. PubMed
  214. Yang K, et al. 2022. J Clin Invest. 132:. PubMed
  215. Jing L, et al. 2022. Front Immunol. 13:864995. PubMed
  216. Wang Z, et al. 2021. J Virol. 95:e0141421. PubMed
  217. Zhang X, et al. 2021. Front Immunol. 12:680068. PubMed
  218. Ma Y, et al. 2015. J Immunol. 195: 3769 - 3780. PubMed
  219. Wong R, et al. 2020. Immunity. 53(5):1078-1094.e7. PubMed
  220. Park HB, et al. 2020. Oncoimmunology. 9:1772663. PubMed
  221. Wang GZ, et al. 2019. Nat Commun. 10:1125. PubMed
  222. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  223. Zhang L, et al. 2021. Methods Mol Biol. 2388:175. PubMed
  224. Yang L, et al. 2021. Cell Death Differ. 28:2616. PubMed
  225. Nabar NR, et al. 2022. Autophagy. 18:204. PubMed
  226. Zhang B, et al. 2021. Nat Biomed Eng. 5:1288. PubMed
  227. Köchl R, et al. 2020. Elife. 9:00. PubMed
  228. Pang D, et al. 2015. Clin Transl Immunology. 4: e41. PubMed
  229. Greenwald AC, et al. 2019. J Exp Med. 216:215. PubMed
  230. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  231. Paul S, et al. 2018. Appl Microbiol Biotechnol. 102:8895. PubMed
  232. Marinescu CI, et al. 2021. Stem Cell Res Ther. 12:319. PubMed
  233. Zhu Y, et al. 2022. Clin Transl Med. 12:e887. PubMed
  234. Lu X, et al. 2016. Nat Commun. 7: 12719. PubMed
  235. Hrdinka M, et al. 2016. PLoS One. 11: 0162863. PubMed
  236. Li Y, et al. 2020. Cell Stem Cell. 27(5):732-747.e7. PubMed
  237. DeVito NC, et al. 2021. Cell Reports. 35(5):109071. PubMed
  238. Noah AC, et al. 2020. J Appl Physiol (1985). 473:128. PubMed
  239. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  240. Hutter K, et al. 2020. FEBS J. . PubMed
  241. Siamishi I, et al. 2020. Cell Reports. 31(11):107756. PubMed
  242. St Clair JB, et al. 2017. PLoS One. 12:e0170556. PubMed
  243. Roy K, et al. 2019. Immunity. 50:616. PubMed
  244. Garo LP, et al. 2019. Cell Rep. 28:3353. PubMed
  245. Reismann D, et al. 2017. Nat Commun.. 10.1038/s41467-017-01538-9. PubMed
  246. Chen X, et al. 2021. Cell Rep. 37:109991. PubMed
  247. Elahi S, et al. 2020. Stem Cell Res. 43:101710. PubMed
  248. Zhang YN, et al. 2020. EBioMedicine. 56:102819. PubMed
  249. Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
  250. Zhang H, et al. 2019. Mol Cell. 76:110. PubMed
  251. Li H, et al. 2020. Nature. 584:274. PubMed
  252. Gu X, et al. 2022. Vaccines (Basel). 10:. PubMed
  253. Ku C, et al. 2015. Genes Dev. 29: 1930-1941. PubMed
  254. Lim CX, et al. 2020. Cell Rep. 3793:30. PubMed
  255. Jamali A, et al. 2020. Cell Reports. 32(9):108099. PubMed
  256. Wittner J, et al. 2022. Mucosal Immunol. 15:668. PubMed
  257. Kang X, et al. 2022. J Immunol Res. 2022:8118577. PubMed
  258. Kondo M, et al. 2016. J Immunol. 196: 563 - 572. PubMed
  259. Hayashi K, et al. 2015. Int Immunol. 27: 435-445. PubMed
  260. Morrison V, et al. 2015. J Immunol. 195: 105 - 115. PubMed
  261. Liu R, et al. 2018. Front Immunol. 9:592. PubMed
  262. Nowlan B, et al. 2019. Haematologica. 105:71. PubMed
  263. Morelli AE, et al. 2020. Cell Rep. 30:3448. PubMed
  264. Zhang W, et al. 2020. Nat Commun. 11:1187. PubMed
  265. Liu J, et al. 2021. Immun Inflamm Dis. 9:299. PubMed
  266. Liu R, et al. 2021. Mol Cell Biol. 41:e0025121. PubMed
  267. Chen C, et al. 2021. J Virol. 95:e0082921. PubMed
  268. Chen RJ, et al. 2022. iScience. 25:105595. PubMed
  269. Georgoudaki A, et al. 2016. Cell Rep. 15: 2000-2011. PubMed
  270. Baomei Wang et al. 2019. Cell reports. 26(6):1614-1626 . PubMed
  271. Weng TY, et al. 2018. Sci Rep. 8:8216. PubMed
  272. Zhang C, et al. 2021. J Virol. 95:e0079021. PubMed
  273. Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
  274. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  275. Hsieh Y, et al. 2014. Infect Immun . 82:2087. PubMed
  276. Schuler F, et al. 2017. Nat Commun. . 10.1038/s41467-017-01850-4. PubMed
  277. Laban H, et al. 2018. J Cell Biol. 217:1503. PubMed
  278. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  279. Raju S, et al. 2020. Cell Reports. 29(9):2556-2564.e3.. PubMed
  280. Sanchez HN, et al. 2020. Nat Commun. 0.5. PubMed
  281. Nguyen HTT, et al. 2021. PLoS Pathog. 17:e1010026. PubMed
  282. Soria-Castro R, et al. 2020. Sci Rep. 10:17802. PubMed
  283. Al-Barwani F, et al. 2014. PLoS One. 9:104523. PubMed
  284. Younes AI, et al. 2021. Transl Oncol. 14:100983. PubMed
  285. Kobia FM, et al. 2020. PLoS Biol. 18:e3000850. PubMed
  286. Ghezraoui H, et al. 2018. Nature. 560:122. PubMed
  287. Tian D, et al. 2019. Nat Commun. 10:4246. PubMed
  288. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  289. Zheng Y, et al. 2022. J Immunol. 208:501. PubMed
  290. Golan K et al. 2018. Cell stem cell. 23(4):572-585 . PubMed
  291. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  292. Velazquez VM, et al. 2017. Mol Ther Methods Clin Dev. 0.277083333. PubMed
  293. Ota T, et al. 2011. J Exp Med. 208:617. PubMed
  294. Tsyklauri O, et al. 2021. EMBO Rep. 22:e50785. PubMed
  295. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  296. Hoechst B, et al. 2016. J Immunol. 195:1517-1523. PubMed
  297. Wu Y, et al. 2015. J Immunol. 195: 2612-2623. PubMed
  298. Takahashi T, et al. 2017. J Exp Med. 10.1084/jem.20160247. PubMed
  299. Li K, et al. 2020. Nat Commun. 4.844444444. PubMed
  300. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  301. Nakamura K, et al. 2018. Cancer Cell. 33:634. PubMed
  302. Pan J, et al. 2022. Front Immunol. 13:812924. PubMed
  303. Srivastava S, et al. 2020. Cancer Cell. 39(2):193-208.e10. PubMed
  304. Iwanami N, et al. 2020. iScience. 23:101260. PubMed
  305. Rossnagl S, et al. 2016. PLoS Biol. 14: 1002562. PubMed
  306. Ioanna E Galani et al. 2017. Immunity. 46(5):875-890 . PubMed
  307. Jing Y, et al. 2019. J Allergy Clin Immunol. 144:1377. PubMed
  308. Awida Z, et al. 2021. Int J Mol Sci. 23:. PubMed
  309. Tham SM, et al. 2021. Biomedicines. 9:. PubMed
  310. Uematsu T, et al. 2015. Sci Rep. 5: 17577. PubMed
RRID
AB_312990 (BioLegend Cat. No. 103205)
AB_312991 (BioLegend Cat. No. 103206)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

B cells, T cell subset, NK cell subset

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4
Cell Type
B cells, NK cells, T cells
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID 5788 View all products for this Gene ID
UniProt
View information about PTPRC on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD45R/B220 Reagents Request Custom Conjugation
Description Clone Applications
PE/Cyanine7 anti-mouse/human CD45R/B220 RA3-6B2 FC
APC/Cyanine7 anti-mouse/human CD45R/B220 RA3-6B2 FC
PE/Dazzle™ 594 anti-mouse/human CD45R/B220 RA3-6B2 FC
APC/Fire™ 750 anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 750™ anti-mouse/human CD45R/B220 RA3-6B2 FC
TotalSeq™-A0103 anti-mouse/human CD45R/B220 RA3-6B2 PG
Spark Blue™ 550 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark NIR™ 685 anti-mouse/human CD45R/B220 RA3-6B2 FC
TotalSeq™-B0103 anti-mouse/human CD45R/B220 RA3-6B2 PG
Ultra-LEAF™ Purified anti-mouse/human CD45R/B220 RA3-6B2 FC,CyTOF®,IHC-F,IHC-P,IP,Activ
APC/Fire™ 810 anti-mouse/human CD45R/B220 RA3-6B2 FC
TotalSeq™-C0103 anti-mouse/human CD45R/B220 RA3-6B2 PG
PE/Fire™ 640 anti-mouse/human CD45R/B220 RA3-6B2 FC
PE/Fire™ 700 anti-mouse/human CD45R/B220 RA3-6B2 FC
FITC anti-mouse/human CD45R/B220 RA3-6B2 FC
PE anti-mouse/human CD45R/B220 RA3-6B2 FC
Alexa Fluor® 594 anti-mouse/human CD45R/B220 RA3-6B2 IHC-F,FC,3D IHC
APC anti-mouse/human CD45R/B220 RA3-6B2 FC
Biotin anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F
PE/Cyanine5 anti-mouse/human CD45R/B220 RA3-6B2 FC
Purified anti-mouse/human CD45R/B220 RA3-6B2 FC,CyTOF®,IHC-F,IHC-P,IP,Activ
Alexa Fluor® 647 anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F,3D IHC,SB
Alexa Fluor® 488 anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F,3D IHC
Pacific Blue™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Alexa Fluor® 700 anti-mouse/human CD45R/B220 RA3-6B2 FC
PerCP anti-mouse/human CD45R/B220 RA3-6B2 FC
PerCP/Cyanine5.5 anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 421™ anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F
Brilliant Violet 570™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 785™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 510™ anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F,SB
Brilliant Violet 650™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 605™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Purified anti-mouse/human CD45R/B220 (Maxpar® Ready) RA3-6B2 FC,CyTOF®
Brilliant Violet 711™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark Violet™ 538 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark YG™ 581 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark YG™ 570 anti-mouse/human CD45R/B220 RA3-6B2 IHC-F
PE/Fire™ 810 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark Blue™ 574 anti-mouse/human CD45R/B220 Antibody RA3-6B2 FC
Spark Violet™ 423 anti-mouse/human CD45R/B220 Antibody RA3-6B2 FC
Spark Red™ 718 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark UV™ 387 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark PLUS UV395™ anti-mouse/human CD45R/B220 RA3-6B2 FC
PerCP/Fire™ 780 anti-mouse/human CD45R/B220 Antibody RA3-6B2 FC
Spark YG™ 593 anti-mouse/human CD45R/B220 (Flexi-Fluor™) Antibody RA3-6B2 FC
Go To Top Version: 2    Revision Date: 04-25-2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Pricing & Availability
Clone
RA3-6B2 (See other available formats)
Regulatory Status
RUO
Other Names
B220
Isotype
Rat IgG2a, κ
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Product Citations
publications
RA3-6B2_FITC
C57BL/6 mouse splenocytes stained with RA3-6B2 FITC
  • RA3-6B2_FITC
    C57BL/6 mouse splenocytes stained with RA3-6B2 FITC
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability Save
103205 50 µg SEK252
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103206 500 µg SEK882
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Description

CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human
Reported Reactivity
Cat
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Abelson murine leukemia virus-induced pre-B tumor cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone RA3-6B2 has been described to react with an epitope on the extracellular domain of the transmembrane CD45 glycoprotein which is dependent upon the expression of exon A and specific carbohydrate residues. Additional reported applications (for the relevant formats) include: immunoprecipitation1, in vitro and in vivo modulation of B cell responses2-4, immunohistochemistry of acetone-fixed frozen sections and formalin-fixed paraffin-embedded sections5,6, and spatial biology (IBEX)14,15.

Application References
  1. Coffman RL. 1982. Immunol. Rev. 69:5. (IP)
  2. George A, et al. 1994. J. Immunol. 152:1014. (Activ)
  3. Asensi V, et al. 1989. Immunology 68:204. (Activ)
  4. Domiati-Saad R, et al. 1993. J. Immunol. 151:5936. (Activ)
  5. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  6. Monteith CE, et al. 1996. Can. J. Vet. Res. 60:193. (IHC)
  7. Shih FF, et al. 2006. J. Immunol. 176:3438. (FC)
  8. Chang C L-T, et al. 2007. J. Immunol. 178:6984.
  9. Fazilleau N, et al. 2007. Nature Immunol. 8:753.
  10. Lang GL, et al. 2008. Blood 111:2158. PubMed
  11. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
  12. del Rio ML, et al. 2011. Transpl. Int. 24:501. (FC) PubMed
  13. Murakami R, et al. 2013. PLoS One. 8:73270. PubMed
  14. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  15. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Katsumura KR, et al. 2018. Proc Natl Acad Sci U S A. 115:E10109. PubMed
  2. Zimmerman SM, et al. 2022. Oncogene. 41:4983. PubMed
  3. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  4. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  5. Wang Z, et al. 2023. Mediators Inflamm. 2023:9810733. PubMed
  6. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  7. Zhao J, et al. 2021. Emerg Microbes Infect. 10:913. PubMed
  8. Hutter K, et al. 2022. Front Immunol. 13:967914. PubMed
  9. Aimaitijiang A, et al. 2022. Genes Cells. 27:25. PubMed
  10. Wang B, et al. 2022. EMBO J. 41:e108946. PubMed
  11. Corral D, et al. 2022. Cell Rep. 39:110715. PubMed
  12. Xu J, et al. 2022. Invest Ophthalmol Vis Sci. 63:15. PubMed
  13. Tatsumi N, et al. 2022. STAR Protoc. 3:101845. PubMed
  14. Meacham CE, et al. 2022. Nat Cell Biol. 24:697. PubMed
  15. Bruggemann TR, et al. 2022. iScience. 25:105185. PubMed
  16. Lunardi A, et al. 2015. Cancer Discovery. 5:550. PubMed
  17. Zaman R, et al. 2021. Immunity. :. PubMed
  18. Wu N, et al. 2020. Cell Rep. 30:1129. PubMed
  19. Schönberger K, et al. 2022. Cell Stem Cell. 29:131. PubMed
  20. Zhang R, et al. 2021. Cell Mol Immunol. 18:1222. PubMed
  21. Israelow B, et al. 2020. bioRxiv. . PubMed
  22. Furuta Y, et al. 2017. PLoS One. 12(2):e0172509. PubMed
  23. Hata E, et al. 2016. Int Immunol. 28: 283 - 292. PubMed
  24. Engel O, et al. 2015. Stroke. 46: 3232 - 3240. PubMed
  25. Kaku H, et al. 2014. J Immunol. 193:5904. PubMed
  26. Stewart I et al. 2018. Immunity. 49(3):477-489 . PubMed
  27. Kim CJ, et al. 2018. Immunity. 49:1034. PubMed
  28. Kelly L, et al. 2011. J Immunol. 187:3026. PubMed
  29. Hewitson JP, et al. 2020. J Immunol. 204:2949. PubMed
  30. Johnson KD, et al. 2022. Blood Adv. 6:1464. PubMed
  31. Chen X, et al. 2021. Theranostics. 11:4655. PubMed
  32. Ota T, et al. 2013. J Immunol. 191:3179. PubMed
  33. Xia S, et al. 2014. J Leukoc Biol. 95:733. PubMed
  34. Tan X, et al. 2016. PLoS One. 11: 0160985. PubMed
  35. Bao H, et al. 2020. Mol Med Rep. 4.675. PubMed
  36. Dong L, et al. 2021. Cancer Cell. . PubMed
  37. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  38. Yang X, et al. 2020. Blood Sci. 2:89. PubMed
  39. Ma C, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  40. Zhu X, et al. 2017. Arch Oral Biol. 10.1016/j.archoralbio.2017.03.010. PubMed
  41. Jones M, et al. 2016. PLoS One. 11: 0157271. PubMed
  42. Wang X, et al. 2016. PLoS Pathog. 12: 1005367. PubMed
  43. Ohyagi M, et al. 2021. Nat Commun. 12:7344. PubMed
  44. Xu F, et al. 2022. Cell Death Discov. 8:142. PubMed
  45. Tu X, et al. 2022. Nat Commun. 13:6977. PubMed
  46. Carbonneau C, et al. 2012. Blood. 119:717. PubMed
  47. Luff DH, et al. 2021. Front Immunol. 631271:12. PubMed
  48. Delgado‐Benito V et al. 2018. Molecular cell. 72(4):636-649 . PubMed
  49. Zanotti KJ, et al. 2019. J Immunol. 202:1573. PubMed
  50. Mariani SA, et al. 2019. Immunity. 50:1439. PubMed
  51. Dey A et al. 2019. The EMBO journal. 38(7) pii: e100293. PubMed
  52. Huang L, et al. 2017. PLoS Biol.. 10.1371/journal.pbio.2001750. PubMed
  53. Dai B, et al. 2022. Theranostics. 12:7603. PubMed
  54. Tanaka Y, et al. 2021. Int J Mol Sci. 22:. PubMed
  55. Fujikura D, et al. 2013. PLoS One. 8:e55321. PubMed
  56. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  57. Qi X, et al. 2019. Nat Med. 25:1225. PubMed
  58. Nakata T, et al. 2020. Proc Natl Acad Sci U S A. 117:28930. PubMed
  59. Yang K, et al. 2022. J Clin Invest. 132:. PubMed
  60. Jing L, et al. 2022. Front Immunol. 13:864995. PubMed
  61. Wang Z, et al. 2021. J Virol. 95:e0141421. PubMed
  62. Zhang X, et al. 2021. Front Immunol. 12:680068. PubMed
  63. Ma Y, et al. 2015. J Immunol. 195: 3769 - 3780. PubMed
  64. Wong R, et al. 2020. Immunity. 53(5):1078-1094.e7. PubMed
  65. Park HB, et al. 2020. Oncoimmunology. 9:1772663. PubMed
  66. Wang GZ, et al. 2019. Nat Commun. 10:1125. PubMed
  67. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  68. Zhang L, et al. 2021. Methods Mol Biol. 2388:175. PubMed
  69. Yang L, et al. 2021. Cell Death Differ. 28:2616. PubMed
  70. Nabar NR, et al. 2022. Autophagy. 18:204. PubMed
  71. Zhang B, et al. 2021. Nat Biomed Eng. 5:1288. PubMed
  72. Köchl R, et al. 2020. Elife. 9:00. PubMed
  73. Pang D, et al. 2015. Clin Transl Immunology. 4: e41. PubMed
  74. Greenwald AC, et al. 2019. J Exp Med. 216:215. PubMed
  75. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  76. Paul S, et al. 2018. Appl Microbiol Biotechnol. 102:8895. PubMed
  77. Marinescu CI, et al. 2021. Stem Cell Res Ther. 12:319. PubMed
  78. Zhu Y, et al. 2022. Clin Transl Med. 12:e887. PubMed
  79. Lu X, et al. 2016. Nat Commun. 7: 12719. PubMed
  80. Hrdinka M, et al. 2016. PLoS One. 11: 0162863. PubMed
  81. Li Y, et al. 2020. Cell Stem Cell. 27(5):732-747.e7. PubMed
  82. DeVito NC, et al. 2021. Cell Reports. 35(5):109071. PubMed
  83. Noah AC, et al. 2020. J Appl Physiol (1985). 473:128. PubMed
  84. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  85. Hutter K, et al. 2020. FEBS J. . PubMed
  86. Siamishi I, et al. 2020. Cell Reports. 31(11):107756. PubMed
  87. St Clair JB, et al. 2017. PLoS One. 12:e0170556. PubMed
  88. Roy K, et al. 2019. Immunity. 50:616. PubMed
  89. Garo LP, et al. 2019. Cell Rep. 28:3353. PubMed
  90. Reismann D, et al. 2017. Nat Commun.. 10.1038/s41467-017-01538-9. PubMed
  91. Chen X, et al. 2021. Cell Rep. 37:109991. PubMed
  92. Elahi S, et al. 2020. Stem Cell Res. 43:101710. PubMed
  93. Zhang YN, et al. 2020. EBioMedicine. 56:102819. PubMed
  94. Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
  95. Zhang H, et al. 2019. Mol Cell. 76:110. PubMed
  96. Li H, et al. 2020. Nature. 584:274. PubMed
  97. Gu X, et al. 2022. Vaccines (Basel). 10:. PubMed
  98. Ku C, et al. 2015. Genes Dev. 29: 1930-1941. PubMed
  99. Lim CX, et al. 2020. Cell Rep. 3793:30. PubMed
  100. Jamali A, et al. 2020. Cell Reports. 32(9):108099. PubMed
  101. Wittner J, et al. 2022. Mucosal Immunol. 15:668. PubMed
  102. Kang X, et al. 2022. J Immunol Res. 2022:8118577. PubMed
  103. Kondo M, et al. 2016. J Immunol. 196: 563 - 572. PubMed
  104. Hayashi K, et al. 2015. Int Immunol. 27: 435-445. PubMed
  105. Morrison V, et al. 2015. J Immunol. 195: 105 - 115. PubMed
  106. Liu R, et al. 2018. Front Immunol. 9:592. PubMed
  107. Nowlan B, et al. 2019. Haematologica. 105:71. PubMed
  108. Morelli AE, et al. 2020. Cell Rep. 30:3448. PubMed
  109. Zhang W, et al. 2020. Nat Commun. 11:1187. PubMed
  110. Liu J, et al. 2021. Immun Inflamm Dis. 9:299. PubMed
  111. Liu R, et al. 2021. Mol Cell Biol. 41:e0025121. PubMed
  112. Chen C, et al. 2021. J Virol. 95:e0082921. PubMed
  113. Chen RJ, et al. 2022. iScience. 25:105595. PubMed
  114. Georgoudaki A, et al. 2016. Cell Rep. 15: 2000-2011. PubMed
  115. Baomei Wang et al. 2019. Cell reports. 26(6):1614-1626 . PubMed
  116. Weng TY, et al. 2018. Sci Rep. 8:8216. PubMed
  117. Zhang C, et al. 2021. J Virol. 95:e0079021. PubMed
  118. Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
  119. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  120. Hsieh Y, et al. 2014. Infect Immun . 82:2087. PubMed
  121. Schuler F, et al. 2017. Nat Commun. . 10.1038/s41467-017-01850-4. PubMed
  122. Laban H, et al. 2018. J Cell Biol. 217:1503. PubMed
  123. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  124. Raju S, et al. 2020. Cell Reports. 29(9):2556-2564.e3.. PubMed
  125. Sanchez HN, et al. 2020. Nat Commun. 0.5. PubMed
  126. Nguyen HTT, et al. 2021. PLoS Pathog. 17:e1010026. PubMed
  127. Soria-Castro R, et al. 2020. Sci Rep. 10:17802. PubMed
  128. Al-Barwani F, et al. 2014. PLoS One. 9:104523. PubMed
  129. Younes AI, et al. 2021. Transl Oncol. 14:100983. PubMed
  130. Kobia FM, et al. 2020. PLoS Biol. 18:e3000850. PubMed
  131. Ghezraoui H, et al. 2018. Nature. 560:122. PubMed
  132. Tian D, et al. 2019. Nat Commun. 10:4246. PubMed
  133. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  134. Zheng Y, et al. 2022. J Immunol. 208:501. PubMed
  135. Golan K et al. 2018. Cell stem cell. 23(4):572-585 . PubMed
  136. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  137. Velazquez VM, et al. 2017. Mol Ther Methods Clin Dev. 0.277083333. PubMed
  138. Ota T, et al. 2011. J Exp Med. 208:617. PubMed
  139. Tsyklauri O, et al. 2021. EMBO Rep. 22:e50785. PubMed
  140. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  141. Hoechst B, et al. 2016. J Immunol. 195:1517-1523. PubMed
  142. Wu Y, et al. 2015. J Immunol. 195: 2612-2623. PubMed
  143. Takahashi T, et al. 2017. J Exp Med. 10.1084/jem.20160247. PubMed
  144. Li K, et al. 2020. Nat Commun. 4.844444444. PubMed
  145. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  146. Nakamura K, et al. 2018. Cancer Cell. 33:634. PubMed
  147. Pan J, et al. 2022. Front Immunol. 13:812924. PubMed
  148. Srivastava S, et al. 2020. Cancer Cell. 39(2):193-208.e10. PubMed
  149. Iwanami N, et al. 2020. iScience. 23:101260. PubMed
  150. Rossnagl S, et al. 2016. PLoS Biol. 14: 1002562. PubMed
  151. Ioanna E Galani et al. 2017. Immunity. 46(5):875-890 . PubMed
  152. Jing Y, et al. 2019. J Allergy Clin Immunol. 144:1377. PubMed
  153. Awida Z, et al. 2021. Int J Mol Sci. 23:. PubMed
  154. Tham SM, et al. 2021. Biomedicines. 9:. PubMed
  155. Uematsu T, et al. 2015. Sci Rep. 5: 17577. PubMed
  156. Katsumura KR, et al. 2018. Proc Natl Acad Sci U S A. 115:E10109. PubMed
  157. Zimmerman SM, et al. 2022. Oncogene. 41:4983. PubMed
  158. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  159. Ji Y, et al. 2023. Nat Cell Biol. 25:726. PubMed
  160. Wang Z, et al. 2023. Mediators Inflamm. 2023:9810733. PubMed
  161. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  162. Zhao J, et al. 2021. Emerg Microbes Infect. 10:913. PubMed
  163. Hutter K, et al. 2022. Front Immunol. 13:967914. PubMed
  164. Aimaitijiang A, et al. 2022. Genes Cells. 27:25. PubMed
  165. Wang B, et al. 2022. EMBO J. 41:e108946. PubMed
  166. Corral D, et al. 2022. Cell Rep. 39:110715. PubMed
  167. Xu J, et al. 2022. Invest Ophthalmol Vis Sci. 63:15. PubMed
  168. Tatsumi N, et al. 2022. STAR Protoc. 3:101845. PubMed
  169. Meacham CE, et al. 2022. Nat Cell Biol. 24:697. PubMed
  170. Bruggemann TR, et al. 2022. iScience. 25:105185. PubMed
  171. Lunardi A, et al. 2015. Cancer Discovery. 5:550. PubMed
  172. Zaman R, et al. 2021. Immunity. :. PubMed
  173. Wu N, et al. 2020. Cell Rep. 30:1129. PubMed
  174. Schönberger K, et al. 2022. Cell Stem Cell. 29:131. PubMed
  175. Zhang R, et al. 2021. Cell Mol Immunol. 18:1222. PubMed
  176. Israelow B, et al. 2020. bioRxiv. . PubMed
  177. Furuta Y, et al. 2017. PLoS One. 12(2):e0172509. PubMed
  178. Hata E, et al. 2016. Int Immunol. 28: 283 - 292. PubMed
  179. Engel O, et al. 2015. Stroke. 46: 3232 - 3240. PubMed
  180. Kaku H, et al. 2014. J Immunol. 193:5904. PubMed
  181. Stewart I et al. 2018. Immunity. 49(3):477-489 . PubMed
  182. Kim CJ, et al. 2018. Immunity. 49:1034. PubMed
  183. Kelly L, et al. 2011. J Immunol. 187:3026. PubMed
  184. Hewitson JP, et al. 2020. J Immunol. 204:2949. PubMed
  185. Johnson KD, et al. 2022. Blood Adv. 6:1464. PubMed
  186. Chen X, et al. 2021. Theranostics. 11:4655. PubMed
  187. Ota T, et al. 2013. J Immunol. 191:3179. PubMed
  188. Xia S, et al. 2014. J Leukoc Biol. 95:733. PubMed
  189. Tan X, et al. 2016. PLoS One. 11: 0160985. PubMed
  190. Bao H, et al. 2020. Mol Med Rep. 4.675. PubMed
  191. Dong L, et al. 2021. Cancer Cell. . PubMed
  192. Yang W, et al. 2020. Nat Commun. 3.553472222. PubMed
  193. Yang X, et al. 2020. Blood Sci. 2:89. PubMed
  194. Ma C, et al. 2022. Proc Natl Acad Sci U S A. 119:. PubMed
  195. Zhu X, et al. 2017. Arch Oral Biol. 10.1016/j.archoralbio.2017.03.010. PubMed
  196. Jones M, et al. 2016. PLoS One. 11: 0157271. PubMed
  197. Wang X, et al. 2016. PLoS Pathog. 12: 1005367. PubMed
  198. Ohyagi M, et al. 2021. Nat Commun. 12:7344. PubMed
  199. Xu F, et al. 2022. Cell Death Discov. 8:142. PubMed
  200. Tu X, et al. 2022. Nat Commun. 13:6977. PubMed
  201. Carbonneau C, et al. 2012. Blood. 119:717. PubMed
  202. Luff DH, et al. 2021. Front Immunol. 631271:12. PubMed
  203. Delgado‐Benito V et al. 2018. Molecular cell. 72(4):636-649 . PubMed
  204. Zanotti KJ, et al. 2019. J Immunol. 202:1573. PubMed
  205. Mariani SA, et al. 2019. Immunity. 50:1439. PubMed
  206. Dey A et al. 2019. The EMBO journal. 38(7) pii: e100293. PubMed
  207. Huang L, et al. 2017. PLoS Biol.. 10.1371/journal.pbio.2001750. PubMed
  208. Dai B, et al. 2022. Theranostics. 12:7603. PubMed
  209. Tanaka Y, et al. 2021. Int J Mol Sci. 22:. PubMed
  210. Fujikura D, et al. 2013. PLoS One. 8:e55321. PubMed
  211. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  212. Qi X, et al. 2019. Nat Med. 25:1225. PubMed
  213. Nakata T, et al. 2020. Proc Natl Acad Sci U S A. 117:28930. PubMed
  214. Yang K, et al. 2022. J Clin Invest. 132:. PubMed
  215. Jing L, et al. 2022. Front Immunol. 13:864995. PubMed
  216. Wang Z, et al. 2021. J Virol. 95:e0141421. PubMed
  217. Zhang X, et al. 2021. Front Immunol. 12:680068. PubMed
  218. Ma Y, et al. 2015. J Immunol. 195: 3769 - 3780. PubMed
  219. Wong R, et al. 2020. Immunity. 53(5):1078-1094.e7. PubMed
  220. Park HB, et al. 2020. Oncoimmunology. 9:1772663. PubMed
  221. Wang GZ, et al. 2019. Nat Commun. 10:1125. PubMed
  222. Mrdjen D et al. 2018. Immunity. 48(2):380-395 . PubMed
  223. Zhang L, et al. 2021. Methods Mol Biol. 2388:175. PubMed
  224. Yang L, et al. 2021. Cell Death Differ. 28:2616. PubMed
  225. Nabar NR, et al. 2022. Autophagy. 18:204. PubMed
  226. Zhang B, et al. 2021. Nat Biomed Eng. 5:1288. PubMed
  227. Köchl R, et al. 2020. Elife. 9:00. PubMed
  228. Pang D, et al. 2015. Clin Transl Immunology. 4: e41. PubMed
  229. Greenwald AC, et al. 2019. J Exp Med. 216:215. PubMed
  230. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  231. Paul S, et al. 2018. Appl Microbiol Biotechnol. 102:8895. PubMed
  232. Marinescu CI, et al. 2021. Stem Cell Res Ther. 12:319. PubMed
  233. Zhu Y, et al. 2022. Clin Transl Med. 12:e887. PubMed
  234. Lu X, et al. 2016. Nat Commun. 7: 12719. PubMed
  235. Hrdinka M, et al. 2016. PLoS One. 11: 0162863. PubMed
  236. Li Y, et al. 2020. Cell Stem Cell. 27(5):732-747.e7. PubMed
  237. DeVito NC, et al. 2021. Cell Reports. 35(5):109071. PubMed
  238. Noah AC, et al. 2020. J Appl Physiol (1985). 473:128. PubMed
  239. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  240. Hutter K, et al. 2020. FEBS J. . PubMed
  241. Siamishi I, et al. 2020. Cell Reports. 31(11):107756. PubMed
  242. St Clair JB, et al. 2017. PLoS One. 12:e0170556. PubMed
  243. Roy K, et al. 2019. Immunity. 50:616. PubMed
  244. Garo LP, et al. 2019. Cell Rep. 28:3353. PubMed
  245. Reismann D, et al. 2017. Nat Commun.. 10.1038/s41467-017-01538-9. PubMed
  246. Chen X, et al. 2021. Cell Rep. 37:109991. PubMed
  247. Elahi S, et al. 2020. Stem Cell Res. 43:101710. PubMed
  248. Zhang YN, et al. 2020. EBioMedicine. 56:102819. PubMed
  249. Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
  250. Zhang H, et al. 2019. Mol Cell. 76:110. PubMed
  251. Li H, et al. 2020. Nature. 584:274. PubMed
  252. Gu X, et al. 2022. Vaccines (Basel). 10:. PubMed
  253. Ku C, et al. 2015. Genes Dev. 29: 1930-1941. PubMed
  254. Lim CX, et al. 2020. Cell Rep. 3793:30. PubMed
  255. Jamali A, et al. 2020. Cell Reports. 32(9):108099. PubMed
  256. Wittner J, et al. 2022. Mucosal Immunol. 15:668. PubMed
  257. Kang X, et al. 2022. J Immunol Res. 2022:8118577. PubMed
  258. Kondo M, et al. 2016. J Immunol. 196: 563 - 572. PubMed
  259. Hayashi K, et al. 2015. Int Immunol. 27: 435-445. PubMed
  260. Morrison V, et al. 2015. J Immunol. 195: 105 - 115. PubMed
  261. Liu R, et al. 2018. Front Immunol. 9:592. PubMed
  262. Nowlan B, et al. 2019. Haematologica. 105:71. PubMed
  263. Morelli AE, et al. 2020. Cell Rep. 30:3448. PubMed
  264. Zhang W, et al. 2020. Nat Commun. 11:1187. PubMed
  265. Liu J, et al. 2021. Immun Inflamm Dis. 9:299. PubMed
  266. Liu R, et al. 2021. Mol Cell Biol. 41:e0025121. PubMed
  267. Chen C, et al. 2021. J Virol. 95:e0082921. PubMed
  268. Chen RJ, et al. 2022. iScience. 25:105595. PubMed
  269. Georgoudaki A, et al. 2016. Cell Rep. 15: 2000-2011. PubMed
  270. Baomei Wang et al. 2019. Cell reports. 26(6):1614-1626 . PubMed
  271. Weng TY, et al. 2018. Sci Rep. 8:8216. PubMed
  272. Zhang C, et al. 2021. J Virol. 95:e0079021. PubMed
  273. Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
  274. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  275. Hsieh Y, et al. 2014. Infect Immun . 82:2087. PubMed
  276. Schuler F, et al. 2017. Nat Commun. . 10.1038/s41467-017-01850-4. PubMed
  277. Laban H, et al. 2018. J Cell Biol. 217:1503. PubMed
  278. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  279. Raju S, et al. 2020. Cell Reports. 29(9):2556-2564.e3.. PubMed
  280. Sanchez HN, et al. 2020. Nat Commun. 0.5. PubMed
  281. Nguyen HTT, et al. 2021. PLoS Pathog. 17:e1010026. PubMed
  282. Soria-Castro R, et al. 2020. Sci Rep. 10:17802. PubMed
  283. Al-Barwani F, et al. 2014. PLoS One. 9:104523. PubMed
  284. Younes AI, et al. 2021. Transl Oncol. 14:100983. PubMed
  285. Kobia FM, et al. 2020. PLoS Biol. 18:e3000850. PubMed
  286. Ghezraoui H, et al. 2018. Nature. 560:122. PubMed
  287. Tian D, et al. 2019. Nat Commun. 10:4246. PubMed
  288. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  289. Zheng Y, et al. 2022. J Immunol. 208:501. PubMed
  290. Golan K et al. 2018. Cell stem cell. 23(4):572-585 . PubMed
  291. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  292. Velazquez VM, et al. 2017. Mol Ther Methods Clin Dev. 0.277083333. PubMed
  293. Ota T, et al. 2011. J Exp Med. 208:617. PubMed
  294. Tsyklauri O, et al. 2021. EMBO Rep. 22:e50785. PubMed
  295. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  296. Hoechst B, et al. 2016. J Immunol. 195:1517-1523. PubMed
  297. Wu Y, et al. 2015. J Immunol. 195: 2612-2623. PubMed
  298. Takahashi T, et al. 2017. J Exp Med. 10.1084/jem.20160247. PubMed
  299. Li K, et al. 2020. Nat Commun. 4.844444444. PubMed
  300. Burton OT, et al. 2018. Clin Exp Allergy. 48:288. PubMed
  301. Nakamura K, et al. 2018. Cancer Cell. 33:634. PubMed
  302. Pan J, et al. 2022. Front Immunol. 13:812924. PubMed
  303. Srivastava S, et al. 2020. Cancer Cell. 39(2):193-208.e10. PubMed
  304. Iwanami N, et al. 2020. iScience. 23:101260. PubMed
  305. Rossnagl S, et al. 2016. PLoS Biol. 14: 1002562. PubMed
  306. Ioanna E Galani et al. 2017. Immunity. 46(5):875-890 . PubMed
  307. Jing Y, et al. 2019. J Allergy Clin Immunol. 144:1377. PubMed
  308. Awida Z, et al. 2021. Int J Mol Sci. 23:. PubMed
  309. Tham SM, et al. 2021. Biomedicines. 9:. PubMed
  310. Uematsu T, et al. 2015. Sci Rep. 5: 17577. PubMed
RRID
AB_312990 (BioLegend Cat. No. 103205)
AB_312991 (BioLegend Cat. No. 103206)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

B cells, T cell subset, NK cell subset

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4
Cell Type
B cells, NK cells, T cells
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID 5788 View all products for this Gene ID
UniProt
View information about PTPRC on UniProt.org

Other Formats

View All CD45R/B220 Reagents Request Custom Conjugation
Description Clone Applications
PE/Cyanine7 anti-mouse/human CD45R/B220 RA3-6B2 FC
APC/Cyanine7 anti-mouse/human CD45R/B220 RA3-6B2 FC
PE/Dazzle™ 594 anti-mouse/human CD45R/B220 RA3-6B2 FC
APC/Fire™ 750 anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 750™ anti-mouse/human CD45R/B220 RA3-6B2 FC
TotalSeq™-A0103 anti-mouse/human CD45R/B220 RA3-6B2 PG
Spark Blue™ 550 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark NIR™ 685 anti-mouse/human CD45R/B220 RA3-6B2 FC
TotalSeq™-B0103 anti-mouse/human CD45R/B220 RA3-6B2 PG
Ultra-LEAF™ Purified anti-mouse/human CD45R/B220 RA3-6B2 FC,CyTOF®,IHC-F,IHC-P,IP,Activ
APC/Fire™ 810 anti-mouse/human CD45R/B220 RA3-6B2 FC
TotalSeq™-C0103 anti-mouse/human CD45R/B220 RA3-6B2 PG
PE/Fire™ 640 anti-mouse/human CD45R/B220 RA3-6B2 FC
PE/Fire™ 700 anti-mouse/human CD45R/B220 RA3-6B2 FC
FITC anti-mouse/human CD45R/B220 RA3-6B2 FC
PE anti-mouse/human CD45R/B220 RA3-6B2 FC
Alexa Fluor® 594 anti-mouse/human CD45R/B220 RA3-6B2 IHC-F,FC,3D IHC
APC anti-mouse/human CD45R/B220 RA3-6B2 FC
Biotin anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F
PE/Cyanine5 anti-mouse/human CD45R/B220 RA3-6B2 FC
Purified anti-mouse/human CD45R/B220 RA3-6B2 FC,CyTOF®,IHC-F,IHC-P,IP,Activ
Alexa Fluor® 647 anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F,3D IHC,SB
Alexa Fluor® 488 anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F,3D IHC
Pacific Blue™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Alexa Fluor® 700 anti-mouse/human CD45R/B220 RA3-6B2 FC
PerCP anti-mouse/human CD45R/B220 RA3-6B2 FC
PerCP/Cyanine5.5 anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 421™ anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F
Brilliant Violet 570™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 785™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 510™ anti-mouse/human CD45R/B220 RA3-6B2 FC,IHC-F,SB
Brilliant Violet 650™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Brilliant Violet 605™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Purified anti-mouse/human CD45R/B220 (Maxpar® Ready) RA3-6B2 FC,CyTOF®
Brilliant Violet 711™ anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark Violet™ 538 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark YG™ 581 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark YG™ 570 anti-mouse/human CD45R/B220 RA3-6B2 IHC-F
PE/Fire™ 810 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark Blue™ 574 anti-mouse/human CD45R/B220 Antibody RA3-6B2 FC
Spark Violet™ 423 anti-mouse/human CD45R/B220 Antibody RA3-6B2 FC
Spark Red™ 718 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark UV™ 387 anti-mouse/human CD45R/B220 RA3-6B2 FC
Spark PLUS UV395™ anti-mouse/human CD45R/B220 RA3-6B2 FC
PerCP/Fire™ 780 anti-mouse/human CD45R/B220 Antibody RA3-6B2 FC
Spark YG™ 593 anti-mouse/human CD45R/B220 (Flexi-Fluor™) Antibody RA3-6B2 FC
Go To Top Version: 2    Revision Date: 04-25-2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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