Loading...

FITC anti-mouse Ly-6G Antibody FITC anti-mouse Ly-6G Antibody

Pricing & Availability
Clone
1A8 (See other available formats)
Regulatory Status
RUO
Other Names
Lymphocyte antigen 6 complex, locus G
Isotype
Rat IgG2a, κ
Ave. Rating
Submit a Review
Product Citations
publications
1A8_FITC_082808.jpg
BALB/cmouse bone marrow cells stained with 1A8 FITC (gated on myeloid cells)
  • 1A8_FITC_082808.jpg
    BALB/cmouse bone marrow cells stained with 1A8 FITC (gated on myeloid cells)
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability Save
127606 500 µg SEK2201
Check Availability


Need larger quantities of this item?
Request Bulk Quote
127605 50 µg SEK748
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

Lymphocyte antigen 6 complex, locus G (Ly-6G), a 21-25 kD GPI-anchored protein, is expressed on the majority of myeloid cells in bone marrow and peripheral granulocytes.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Ly-6G transfected EL-4J cell line.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for other applications.

Excitation Laser
Blue Laser (488 nm)
Application Notes

While 1A8 recognizes only Ly-6G, clone RB6-8C5 recognizes both Ly-6G and Ly-6C. Clone RB6-8C5 binds with high affinity to mouse Ly-6G molecules and to a lower extent to Ly-6C15. Clone RB6-8C5 impairs the binding of anti-mouse Ly-6G clone 1A815. However, clone RB6-8C5 is able to stain in the presence of anti-mouse Ly-6C clone HK1.416.

Additional reported applications (for the relevant formats) include: immunohistochemistry9 of frozen sections10 and paraffin-embedded sections11, depletion4, 12-14, and spatial biology (IBEX)20,21. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for in vivo studies or highly sensitive assays (Cat. No. 127632, 127649, 127650, 127661 and 127662).

Application References
  1. Fleming TJ, et al. 1993. J. Immunol. 151:2399. (FC)
  2. Daley JM, et al. 2008. J. Leukocyte Biol. 83:1. (FC)
  3. Dietlin TA, et al. 2007. J. Leukocyte Biol. 81:1205. (FC)
  4. Daley J, et al. 2007. J. Leukocyte Biol. doi:10.1189. (Deplete) PubMed
  5. Tadagavadi RK, et al. 2010. J. Immunol. 185:4904. PubMed
  6. Sumagin R, et al. 2010. J. Immunol. 185:7057. PubMed
  7. Guiducci C, et al. 2010. J. Exp Med. 207:2931. PubMed
  8. Fujita M, et al. 2011. Cancer Res. 71:2664. PubMed
  9. Van Leeuwen, et al. 2008. Arterioscler. Thromb. Vasc. Biol. 28:84. (IHC)
  10. Kowanetz M, et al. 2010. P. Natl. Acad. Sci. USA 107:21248. [supplementary data] (IHC)
  11. Esbona K, et al. 2016. Breast Cancer Res. 18:35. (IHC)
  12. Wojtasiak M, et al. 2010. J. Gen. Virol. 91:2158. (FC, Deplete)
  13. Jaeger BN, et al. 2012. J. Exp. Med. 209:565. (Deplete)
  14. Wozniak KL, et al. 2012. BMC Immunol. 13:65 (FC, Deplete)
  15. Ribechini E, et al. 2009. Eur. J. Immunol. 39:3538.
  16. Ng LG, et al. 2011. J Invest. Dermatol. 131:2058. PubMed
  17. Ma C, et al. 2012. J. Leukoc. Biol. 92:1199.
  18. McCartney-Francis, N, et al. 2014. J Leukoc. Biol. 96:917. PubMed
  19. Her Z, et al. 2014. EMBO Mol. Med. 7:24. PubMed
  20. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  21. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Frieler RA, et al. 2017. Exp Neurol. 298:104. PubMed
  2. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  3. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  4. Gordan S, et al. 2020. Cell Reports. 29(10):3033-3046.e4.. PubMed
  5. Pohlmeier L, et al. 2021. Allergy. 76:2030. PubMed
  6. Li T, et al. 2022. J Exp Med. 219: . PubMed
  7. Yang Y, et al. 2022. FEBS J. 289:5279. PubMed
  8. Yue Y, et al. 2022. Nat Biomed Eng. 6:898. PubMed
  9. Zhu Y, et al. 2023. J Ethnopharmacol. 301:115763. PubMed
  10. Xu Y, et al. 2023. EMBO Rep. 24:e55503. PubMed
  11. Xu H, et al. 2022. Aging Dis. 13:1875. PubMed
  12. Pavliuchenko N, et al. 2023. Front Immunol. 13:1035226. PubMed
  13. Tsioti I, et al. 2023. J Neuroinflammation. 20:25. PubMed
  14. Zong P, et al. 2022. Nat Cardiovasc Res. 1:344. PubMed
  15. Sanmarco LM, et al. 2022. Nature. 611:801. PubMed
  16. Peng J, et al. 2023. Am J Reprod Immunol. 89:e13678. PubMed
  17. Le DT, et al. 2023. iScience. 26:106059. PubMed
  18. Veras FP, et al. 2023. Respir Res. 24:66. PubMed
  19. Doke T, et al. 2023. Nat Metab. 5:414. PubMed
  20. Tang C, et al. 2023. Nat Commun. 14:1493. PubMed
  21. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  22. Ma X, et al. 2023. Nat Commun. 14:1606. PubMed
  23. Park JA, et al. 2023. J Immunother Cancer. 11:. PubMed
  24. Chung JY, et al. 2023. Nat Commun. 14:1794. PubMed
  25. Zhu CL, et al. 2023. Int J Biol Sci. 19:1413. PubMed
  26. Silva BM, et al. 2023. J Clin Invest. 133:. PubMed
  27. Cui B, et al. 2023. Int Immunopharmacol. 120:110240. PubMed
  28. Oh J, et al. 2023. Nat Commun. 14:3278. PubMed
  29. Valladao A, et al. 2016. J Immunol. 197(12):4541-4551. PubMed
  30. Campbell IK, Leong D 2016. J Immunol. 197(11):4392-4402. PubMed
  31. Sun L, et al. 2021. Cancer Cell. 39:1361. PubMed
  32. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  33. He R, et al. 2021. J Immunol. 206:2353. PubMed
  34. Lefebvre MN, et al. 2021. Cell Rep. 37:109956. PubMed
  35. Suresh R, et al. 2020. J Immunother Cancer. 8:. PubMed
  36. Okajima T, et al. 2021. Front Immunol. 12:738041. PubMed
  37. Tripathi H, et al. 2020. J Mol Cell Cardiol. 149:95. PubMed
  38. Kim S, et al. 2020. Immunity. 53(4):759-774.e9. PubMed
  39. Garcia-Fabiani MB, et al. 2020. Methods Enzymol. 632:369. PubMed
  40. Miller CM, et al. 2020. J Virol. 94:00:00. PubMed
  41. Long M, et al. 2017. J Immunol. 198(2):862-872. PubMed
  42. Oliveira-Lima OC, et al. 2015. Immunobiology. . PubMed
  43. Mandraju R, et al. 2014. J Immunol. 192:4303. PubMed
  44. Patsalos A, et al. 2019. J Immunol. 203:1532. PubMed
  45. Lin R, et al. 2020. Sci Rep. 10:14397. PubMed
  46. Yang C, et al. 2021. J Immunother Cancer. 9:. PubMed
  47. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  48. Johnson KD, et al. 2022. Blood Adv. 6:1464. PubMed
  49. Clark K, et al. 2015. J Autoimmun. Available online 21 August 2015. PubMed
  50. Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
  51. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  52. Huai W, et al. 2019. J Exp Med. 216:772. PubMed
  53. Han J, et al. 2022. FEBS J. 289:417. PubMed
  54. Larsen SE, et al. 2021. Sci Rep. 11:9040. PubMed
  55. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  56. Torre S, et al. 2016. Nat Immunol. 10.1038/ni.3581. PubMed
  57. Montufar-Solis D, Klein J 2016. PLoS One. 11: 014611. PubMed
  58. Wang C, et al. 2015. Sci Rep. 5: 14124. PubMed
  59. Park JA, et al. 2021. J Hematol Oncol. 14:142. PubMed
  60. Bae SH, et al. 2021. Theranostics. 11:2522. PubMed
  61. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  62. Mitsune A, et al. 2021. Respir Res. 22:232. PubMed
  63. Castiglioni A, et al. 2015. PLoS One. 10:128094. PubMed
  64. Guesdon W, et al. 2015. J Infect Dis. 212: 1332 - 1340. PubMed
  65. Strother R, et al. 2016. J Immunol. 197(11):4301-4311. PubMed
  66. Rao S, et al. 2017. Cell. 168(3):503-516.e12. PubMed
  67. LeBlond ND, et al. 2020. J Lipid Res. 61:1697. PubMed
  68. Fujikura D, et al. 2013. PLoS One. 8:e55321. PubMed
  69. Ueki H, et al. 2020. Nat Protoc. 15:1041. PubMed
  70. Saika A, et al. 2020. FASEB Bioadv. 2:59. PubMed
  71. Nguyen CM, et al. 2019. Diabetes. 68:1499. PubMed
  72. Wang H et al. 2017. Developmental cell. 40(6):566-582 . PubMed
  73. Pan W et al. 2017. Immunity. 47(2):284-297 . PubMed
  74. Billi AC, et al. 2019. JCI Insight. 4:8. PubMed
  75. Han YH, et al. 2021. Science. 373:. PubMed
  76. Dieterich LC, et al. 2019. International Journal of Cancer. 145(10):2804-2815. PubMed
  77. Diao N, et al. 2016. Sci Rep. 6:34672. PubMed
  78. Ellis G, et al. 2015. EMBO Rep. 16: 1203-1218. PubMed
  79. Wang L, et al. 2017. Front Immunol.. 10.3389/fimmu.2017.01754. PubMed
  80. Luan HH et al. 2019. Cell. 178(5):1231-1244 . PubMed
  81. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  82. Wu X, et al. 2021. Elife. 10:. PubMed
  83. Opzoomer JW, et al. 2021. Sci Adv. 7:eabg9518. PubMed
  84. Abad C, et al. 2014. J Leukoc Biol. 95:357. PubMed
  85. Syed A, et al. 2015. Infect Immun . 83: 3428-3437. PubMed
  86. Liu Z, et al. 2016. J Biol Chem. 291: 1441 - 1447. PubMed
  87. Ratitong B, et al. 2021. Cell Reports. 35(7):109139. PubMed
  88. Na YR, et al. 2020. Cell Rep. 107643:31. PubMed
  89. Cheng K, et al. 2021. Nat Commun. 12:2041. PubMed
  90. Kotfis K, et al. 2020. British Journal of Pharmacology. 49(1):66-72. PubMed
  91. Jin RM, et al. 2017. J Immunol. 198:352. PubMed
  92. Xiao P, et al. 2019. J Exp Med. 216:337. PubMed
  93. Lagares D, et al. 2017. Sci Transl Med. 9:eaal3765. PubMed
  94. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  95. Kimball AS et al. 2019. Immunity. 51(2):258-271 . PubMed
  96. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  97. Aegerter H, et al. 2020. Nat Immunol. 0.975694444. PubMed
  98. Jacome-Galarza C, et al. 2011. J Bone Miner Res. 26:1207. PubMed
  99. Huixin Xu et al. 2018. EMBO molecular medicine. 10(9) pii: e8931. PubMed
  100. Geng S, et al. 2021. JCI Insight. 6:. PubMed
  101. Synn CB, et al. 2022. Clin Transl Immunology. 11:e1364. PubMed
  102. Morales-Mantilla DE, et al. 2022. Elife. 11:. PubMed
  103. Chen M, et al. 2021. Oncol Lett. 21:435. PubMed
  104. Minogue A, et al. 2014. Neurobiol Aging. 35:1442. PubMed
  105. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  106. Zheng J, et al. 2020. bioRxiv. . PubMed
  107. Mao FY, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:395. PubMed
  108. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  109. Patel S, et al. 2019. Viruses. 0.877083333. PubMed
  110. Mishra BB, et al. 2017. Nat Microbiol. 2:17072. PubMed
  111. Roy K, et al. 2019. Immunity. 50:616. PubMed
  112. Bradley KC, et al. 2019. Cell Rep. 28:245. PubMed
  113. Christ A, et al. 2018. Cell. 172:162. PubMed
  114. Zhao X, et al. 2022. Nat Protoc. 17:2240. PubMed
  115. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  116. Elahi S, et al. 2020. Stem Cell Res. 43:101710. PubMed
  117. Gousopoulos E, et al. 2016. Am J Pathol. 186:2193-2203. PubMed
  118. Radjabova V, et al. 2015. J Immunol. 195: 3149 - 3159. PubMed
  119. Li Z, et al. 2018. Front Immunol. 9:347. PubMed
  120. He J, et al. 2019. J Clin Invest. 130. PubMed
  121. Yu L, et al. 2019. Elife. 8:e46677. PubMed
  122. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  123. Shen M, et al. 2022. Nat Cancer. 3:60. PubMed
  124. Flögel U, et al. 2021. Nat Commun. 12:5847. PubMed
  125. Wu M, et al. 2013. Proc Natl Acad Sci U S A. 110:9439. PubMed
  126. Weinheimer-Haus E, et al. 2014. PLoS One. 9:91355. PubMed
  127. Ericson J, et al. 2014. PLoS One. 9:108553. PubMed
  128. Shih Y, et al. 2015. JPEN J Parenter Enteral Nutr. . PubMed
  129. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  130. Fischer KJ, et al. 2019. J Immunol. 202:2027. PubMed
  131. Challa TD, et al. 2020. Cell Reports. 30(10):3424-3433. PubMed
  132. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  133. Uderhardt S, et al. 2019. Cell. 177:541. PubMed
  134. Hermetet F, et al. 2019. Nat Commun. 10:523. PubMed
  135. Nagatake T, et al. 2018. Int Immunol. 30:471. PubMed
  136. Shevchenko MA, et al. 2018. J Immunol Res. 8:53. PubMed
  137. Covarrubias AJ, et al. 2020. Nat Metab. 1265:2. PubMed
  138. Zheng J, et al. 2020. Nature. . PubMed
  139. Kim P, et al. 2015. Infect Immun . 83: 2992 - 3002. PubMed
  140. Robinett RA et al. 2018. Cell systems. 7(1):41-48 . PubMed
  141. Rebecca S Dickinson et al. 2017. Wellcome open research. 0.155555556 . PubMed
  142. Simpson K, et al. 2012. J Immunol. 189:5533. PubMed
  143. Nuro-Gyina PK, et al. 2021. J Immunol. 207:868. PubMed
  144. Zeng Q, et al. 2022. iScience. 25:105151. PubMed
  145. Giampazolias E, et al. 2021. Cell. . PubMed
  146. Prizant H, et al. 2021. Cell Reports. 36:109523. PubMed
  147. Xu P, et al. 2020. Cancer Immunol Res. 8:1193. PubMed
  148. Winchell CG, et al. 2020. Front Immunol. 1.077083333. PubMed
  149. Li YT, et al. 2019. Elife. 8:e47642. PubMed
  150. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  151. Nagatake T, et al. 2018. J Allergy Clin Immunol. 142:470. PubMed
  152. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  153. Qin W, et al. 2022. Bio Protoc. 12:e4287. PubMed
  154. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  155. Shibuya M, et al. 2021. iScience. 24:103131. PubMed
  156. Taya M, et al. 2020. Endocr Relat Cancer. 27:261. PubMed
  157. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  158. Xu G, et al. 2020. Cell Rep. 32:108170. PubMed
  159. Thomas DG et al. 2018. Cell reports. 25(13):3774-3785 . PubMed
  160. Lai SM et al. 2018. Cell reports. 25(11):3099-3109 . PubMed
  161. Chen ST et al. 2019. Cell host & microbe. 25(4):602-616 . PubMed
  162. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  163. Makino A, et al. 2021. iScience. 24:103201. PubMed
  164. Gao Z, et al. 2022. J Inflamm Res. 15:3337. PubMed
  165. Njock MS, et al. 2022. J Extracell Vesicles. 11:e12228. PubMed
  166. Gorina R, et al. 2014. J Immunol. 192:324. PubMed
  167. Nacer A, et al. 2014. PLoS Pathog. 10:1004528. PubMed
  168. Gamradt P, et al. 2016. PLoS Pathog. 12:e1006032. PubMed
  169. Varikuti S, et al. 2020. Br J Cancer. 122:1005. PubMed
  170. Cartwright ANR, et al. 2021. Cancer Immunol Res. 9:470. PubMed
  171. LeBlond ND, et al. 2020. J Lipid Res. 61:1697. PubMed
  172. Zhu YP et al. 2018. Cell reports. 24(9):2329-2341 . PubMed
  173. van Geffen C, et al. 2021. Front Immunol. 12:695933. PubMed
  174. Gu H, et al. 2021. Elife. 10:. PubMed
  175. Issah Y, et al. 2021. Elife. 10:. PubMed
  176. Wei Y, et al. 2021. Endocrinology. 162(8):. PubMed
  177. Asadi Shahmirzadi A, et al. 2020. Cell Metabolism. 32(3):447-456.e6. PubMed
  178. Xu C, et al. 2020. Immunity. 53(2):417-428.e4. PubMed
  179. Sparber F, et al. 2019. Cell Host Microbe. 25:389. PubMed
  180. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  181. Gong P, et al. 2022. Cell Death Discov. 8:466. PubMed
  182. Danzer H, et al. 2020. Elife. 9:00. PubMed
  183. Willemze RA, et al. 2019. Mol Med. 25:01:00. PubMed
  184. Jain A, et al. 2020. Nat Immunol. 0.920138889. PubMed
  185. Nakamura K, et al. 2018. Cancer Cell. 33:634. PubMed
  186. Smith LK, et al. 2021. Elife. 10:. PubMed
  187. Schmit T, et al. 2022. Cell Rep. 38:110456. PubMed
  188. Lee GR, et al. 2021. JCI Insight. 6:. PubMed
  189. Chen J, et al. 2014. Cell Res. 24:1050. PubMed
  190. Xu Y, et al. 2014. Proc Natl Acad Sci U S A. 111:6371. PubMed
  191. Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
  192. Lee EKS, et al. 2018. Cell Host Microbe. 23:121. PubMed
  193. Dyer DP et al. 2019. Immunity. 50(2):378-389 . PubMed
  194. Orr MT, et al. 2019. NPJ Vaccines. 4:1. PubMed
  195. Geng S, et al. 2019. Sci Adv. 5:eaav2309. PubMed
  196. Rappe JCF, et al. 2021. J Exp Med. 218:. PubMed
  197. Rivera CA, et al. 2022. Immunity. 55:129. PubMed
  198. Awida Z, et al. 2021. Int J Mol Sci. 23:. PubMed
  199. Caporarello N, et al. 2022. Nat Commun. 13:4170. PubMed
  200. Zhang H, et al. 2022. Commun Biol. 5:916. PubMed
  201. Stadtmann A, et al. 2015. J Immunol. 195: 1152-1161. PubMed
  202. Jia H, et al. 2016. J Immunol. 197: 859 - 871. PubMed
  203. Heyde A, et al. 2021. Cell. 184(5):1348-1361.e22. PubMed
  204. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  205. Tian T, et al. 2020. Cancer Immunol Res. 660:8. PubMed
  206. Buschor S, et al. 2017. PLoS Pathogens. 13(6):e1006476. PubMed
  207. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  208. Aggarwal N, et al. 2021. Cell Rep. 37:110170. PubMed
  209. Chuang LT, et al. 2021. Molecules. 26:. PubMed
  210. Singh N, et al. 2016. Dis Model Mech. 9: 885 - 897. PubMed
  211. Cojohari O, Peppenelli M, Chan G 2016. Blood. 128: 529 - 541. PubMed
  212. Frieler RA, et al. 2017. Exp Neurol. 298:104. PubMed
  213. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  214. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  215. Gordan S, et al. 2020. Cell Reports. 29(10):3033-3046.e4.. PubMed
  216. Pohlmeier L, et al. 2021. Allergy. 76:2030. PubMed
  217. Li T, et al. 2022. J Exp Med. 219: . PubMed
  218. Yang Y, et al. 2022. FEBS J. 289:5279. PubMed
  219. Yue Y, et al. 2022. Nat Biomed Eng. 6:898. PubMed
  220. Zhu Y, et al. 2023. J Ethnopharmacol. 301:115763. PubMed
  221. Xu Y, et al. 2023. EMBO Rep. 24:e55503. PubMed
  222. Xu H, et al. 2022. Aging Dis. 13:1875. PubMed
  223. Pavliuchenko N, et al. 2023. Front Immunol. 13:1035226. PubMed
  224. Tsioti I, et al. 2023. J Neuroinflammation. 20:25. PubMed
  225. Zong P, et al. 2022. Nat Cardiovasc Res. 1:344. PubMed
  226. Sanmarco LM, et al. 2022. Nature. 611:801. PubMed
  227. Peng J, et al. 2023. Am J Reprod Immunol. 89:e13678. PubMed
  228. Le DT, et al. 2023. iScience. 26:106059. PubMed
  229. Veras FP, et al. 2023. Respir Res. 24:66. PubMed
  230. Doke T, et al. 2023. Nat Metab. 5:414. PubMed
  231. Tang C, et al. 2023. Nat Commun. 14:1493. PubMed
  232. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  233. Ma X, et al. 2023. Nat Commun. 14:1606. PubMed
  234. Park JA, et al. 2023. J Immunother Cancer. 11:. PubMed
  235. Chung JY, et al. 2023. Nat Commun. 14:1794. PubMed
  236. Zhu CL, et al. 2023. Int J Biol Sci. 19:1413. PubMed
  237. Silva BM, et al. 2023. J Clin Invest. 133:. PubMed
  238. Cui B, et al. 2023. Int Immunopharmacol. 120:110240. PubMed
  239. Oh J, et al. 2023. Nat Commun. 14:3278. PubMed
  240. Valladao A, et al. 2016. J Immunol. 197(12):4541-4551. PubMed
  241. Campbell IK, Leong D 2016. J Immunol. 197(11):4392-4402. PubMed
  242. Sun L, et al. 2021. Cancer Cell. 39:1361. PubMed
  243. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  244. He R, et al. 2021. J Immunol. 206:2353. PubMed
  245. Lefebvre MN, et al. 2021. Cell Rep. 37:109956. PubMed
  246. Suresh R, et al. 2020. J Immunother Cancer. 8:. PubMed
  247. Okajima T, et al. 2021. Front Immunol. 12:738041. PubMed
  248. Tripathi H, et al. 2020. J Mol Cell Cardiol. 149:95. PubMed
  249. Kim S, et al. 2020. Immunity. 53(4):759-774.e9. PubMed
  250. Garcia-Fabiani MB, et al. 2020. Methods Enzymol. 632:369. PubMed
  251. Miller CM, et al. 2020. J Virol. 94:00:00. PubMed
  252. Long M, et al. 2017. J Immunol. 198(2):862-872. PubMed
  253. Oliveira-Lima OC, et al. 2015. Immunobiology. . PubMed
  254. Mandraju R, et al. 2014. J Immunol. 192:4303. PubMed
  255. Patsalos A, et al. 2019. J Immunol. 203:1532. PubMed
  256. Lin R, et al. 2020. Sci Rep. 10:14397. PubMed
  257. Yang C, et al. 2021. J Immunother Cancer. 9:. PubMed
  258. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  259. Johnson KD, et al. 2022. Blood Adv. 6:1464. PubMed
  260. Clark K, et al. 2015. J Autoimmun. Available online 21 August 2015. PubMed
  261. Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
  262. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  263. Huai W, et al. 2019. J Exp Med. 216:772. PubMed
  264. Han J, et al. 2022. FEBS J. 289:417. PubMed
  265. Larsen SE, et al. 2021. Sci Rep. 11:9040. PubMed
  266. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  267. Torre S, et al. 2016. Nat Immunol. 10.1038/ni.3581. PubMed
  268. Montufar-Solis D, Klein J 2016. PLoS One. 11: 014611. PubMed
  269. Wang C, et al. 2015. Sci Rep. 5: 14124. PubMed
  270. Park JA, et al. 2021. J Hematol Oncol. 14:142. PubMed
  271. Bae SH, et al. 2021. Theranostics. 11:2522. PubMed
  272. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  273. Mitsune A, et al. 2021. Respir Res. 22:232. PubMed
  274. Castiglioni A, et al. 2015. PLoS One. 10:128094. PubMed
  275. Guesdon W, et al. 2015. J Infect Dis. 212: 1332 - 1340. PubMed
  276. Strother R, et al. 2016. J Immunol. 197(11):4301-4311. PubMed
  277. Rao S, et al. 2017. Cell. 168(3):503-516.e12. PubMed
  278. LeBlond ND, et al. 2020. J Lipid Res. 61:1697. PubMed
  279. Fujikura D, et al. 2013. PLoS One. 8:e55321. PubMed
  280. Ueki H, et al. 2020. Nat Protoc. 15:1041. PubMed
  281. Saika A, et al. 2020. FASEB Bioadv. 2:59. PubMed
  282. Nguyen CM, et al. 2019. Diabetes. 68:1499. PubMed
  283. Wang H et al. 2017. Developmental cell. 40(6):566-582 . PubMed
  284. Pan W et al. 2017. Immunity. 47(2):284-297 . PubMed
  285. Billi AC, et al. 2019. JCI Insight. 4:8. PubMed
  286. Han YH, et al. 2021. Science. 373:. PubMed
  287. Dieterich LC, et al. 2019. International Journal of Cancer. 145(10):2804-2815. PubMed
  288. Diao N, et al. 2016. Sci Rep. 6:34672. PubMed
  289. Ellis G, et al. 2015. EMBO Rep. 16: 1203-1218. PubMed
  290. Wang L, et al. 2017. Front Immunol.. 10.3389/fimmu.2017.01754. PubMed
  291. Luan HH et al. 2019. Cell. 178(5):1231-1244 . PubMed
  292. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  293. Wu X, et al. 2021. Elife. 10:. PubMed
  294. Opzoomer JW, et al. 2021. Sci Adv. 7:eabg9518. PubMed
  295. Abad C, et al. 2014. J Leukoc Biol. 95:357. PubMed
  296. Syed A, et al. 2015. Infect Immun . 83: 3428-3437. PubMed
  297. Liu Z, et al. 2016. J Biol Chem. 291: 1441 - 1447. PubMed
  298. Ratitong B, et al. 2021. Cell Reports. 35(7):109139. PubMed
  299. Na YR, et al. 2020. Cell Rep. 107643:31. PubMed
  300. Cheng K, et al. 2021. Nat Commun. 12:2041. PubMed
  301. Kotfis K, et al. 2020. British Journal of Pharmacology. 49(1):66-72. PubMed
  302. Jin RM, et al. 2017. J Immunol. 198:352. PubMed
  303. Xiao P, et al. 2019. J Exp Med. 216:337. PubMed
  304. Lagares D, et al. 2017. Sci Transl Med. 9:eaal3765. PubMed
  305. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  306. Kimball AS et al. 2019. Immunity. 51(2):258-271 . PubMed
  307. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  308. Aegerter H, et al. 2020. Nat Immunol. 0.975694444. PubMed
  309. Jacome-Galarza C, et al. 2011. J Bone Miner Res. 26:1207. PubMed
  310. Huixin Xu et al. 2018. EMBO molecular medicine. 10(9) pii: e8931. PubMed
  311. Geng S, et al. 2021. JCI Insight. 6:. PubMed
  312. Synn CB, et al. 2022. Clin Transl Immunology. 11:e1364. PubMed
  313. Morales-Mantilla DE, et al. 2022. Elife. 11:. PubMed
  314. Chen M, et al. 2021. Oncol Lett. 21:435. PubMed
  315. Minogue A, et al. 2014. Neurobiol Aging. 35:1442. PubMed
  316. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  317. Zheng J, et al. 2020. bioRxiv. . PubMed
  318. Mao FY, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:395. PubMed
  319. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  320. Patel S, et al. 2019. Viruses. 0.877083333. PubMed
  321. Mishra BB, et al. 2017. Nat Microbiol. 2:17072. PubMed
  322. Roy K, et al. 2019. Immunity. 50:616. PubMed
  323. Bradley KC, et al. 2019. Cell Rep. 28:245. PubMed
  324. Christ A, et al. 2018. Cell. 172:162. PubMed
  325. Zhao X, et al. 2022. Nat Protoc. 17:2240. PubMed
  326. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  327. Elahi S, et al. 2020. Stem Cell Res. 43:101710. PubMed
  328. Gousopoulos E, et al. 2016. Am J Pathol. 186:2193-2203. PubMed
  329. Radjabova V, et al. 2015. J Immunol. 195: 3149 - 3159. PubMed
  330. Li Z, et al. 2018. Front Immunol. 9:347. PubMed
  331. He J, et al. 2019. J Clin Invest. 130. PubMed
  332. Yu L, et al. 2019. Elife. 8:e46677. PubMed
  333. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  334. Shen M, et al. 2022. Nat Cancer. 3:60. PubMed
  335. Flögel U, et al. 2021. Nat Commun. 12:5847. PubMed
  336. Wu M, et al. 2013. Proc Natl Acad Sci U S A. 110:9439. PubMed
  337. Weinheimer-Haus E, et al. 2014. PLoS One. 9:91355. PubMed
  338. Ericson J, et al. 2014. PLoS One. 9:108553. PubMed
  339. Shih Y, et al. 2015. JPEN J Parenter Enteral Nutr. . PubMed
  340. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  341. Fischer KJ, et al. 2019. J Immunol. 202:2027. PubMed
  342. Challa TD, et al. 2020. Cell Reports. 30(10):3424-3433. PubMed
  343. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  344. Uderhardt S, et al. 2019. Cell. 177:541. PubMed
  345. Hermetet F, et al. 2019. Nat Commun. 10:523. PubMed
  346. Nagatake T, et al. 2018. Int Immunol. 30:471. PubMed
  347. Shevchenko MA, et al. 2018. J Immunol Res. 8:53. PubMed
  348. Covarrubias AJ, et al. 2020. Nat Metab. 1265:2. PubMed
  349. Zheng J, et al. 2020. Nature. . PubMed
  350. Kim P, et al. 2015. Infect Immun . 83: 2992 - 3002. PubMed
  351. Robinett RA et al. 2018. Cell systems. 7(1):41-48 . PubMed
  352. Rebecca S Dickinson et al. 2017. Wellcome open research. 0.155555556 . PubMed
  353. Simpson K, et al. 2012. J Immunol. 189:5533. PubMed
  354. Nuro-Gyina PK, et al. 2021. J Immunol. 207:868. PubMed
  355. Zeng Q, et al. 2022. iScience. 25:105151. PubMed
  356. Giampazolias E, et al. 2021. Cell. . PubMed
  357. Prizant H, et al. 2021. Cell Reports. 36:109523. PubMed
  358. Xu P, et al. 2020. Cancer Immunol Res. 8:1193. PubMed
  359. Winchell CG, et al. 2020. Front Immunol. 1.077083333. PubMed
  360. Li YT, et al. 2019. Elife. 8:e47642. PubMed
  361. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  362. Nagatake T, et al. 2018. J Allergy Clin Immunol. 142:470. PubMed
  363. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  364. Qin W, et al. 2022. Bio Protoc. 12:e4287. PubMed
  365. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  366. Shibuya M, et al. 2021. iScience. 24:103131. PubMed
  367. Taya M, et al. 2020. Endocr Relat Cancer. 27:261. PubMed
  368. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  369. Xu G, et al. 2020. Cell Rep. 32:108170. PubMed
  370. Thomas DG et al. 2018. Cell reports. 25(13):3774-3785 . PubMed
  371. Lai SM et al. 2018. Cell reports. 25(11):3099-3109 . PubMed
  372. Chen ST et al. 2019. Cell host & microbe. 25(4):602-616 . PubMed
  373. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  374. Makino A, et al. 2021. iScience. 24:103201. PubMed
  375. Gao Z, et al. 2022. J Inflamm Res. 15:3337. PubMed
  376. Njock MS, et al. 2022. J Extracell Vesicles. 11:e12228. PubMed
  377. Gorina R, et al. 2014. J Immunol. 192:324. PubMed
  378. Nacer A, et al. 2014. PLoS Pathog. 10:1004528. PubMed
  379. Gamradt P, et al. 2016. PLoS Pathog. 12:e1006032. PubMed
  380. Varikuti S, et al. 2020. Br J Cancer. 122:1005. PubMed
  381. Cartwright ANR, et al. 2021. Cancer Immunol Res. 9:470. PubMed
  382. LeBlond ND, et al. 2020. J Lipid Res. 61:1697. PubMed
  383. Zhu YP et al. 2018. Cell reports. 24(9):2329-2341 . PubMed
  384. van Geffen C, et al. 2021. Front Immunol. 12:695933. PubMed
  385. Gu H, et al. 2021. Elife. 10:. PubMed
  386. Issah Y, et al. 2021. Elife. 10:. PubMed
  387. Wei Y, et al. 2021. Endocrinology. 162(8):. PubMed
  388. Asadi Shahmirzadi A, et al. 2020. Cell Metabolism. 32(3):447-456.e6. PubMed
  389. Xu C, et al. 2020. Immunity. 53(2):417-428.e4. PubMed
  390. Sparber F, et al. 2019. Cell Host Microbe. 25:389. PubMed
  391. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  392. Gong P, et al. 2022. Cell Death Discov. 8:466. PubMed
  393. Danzer H, et al. 2020. Elife. 9:00. PubMed
  394. Willemze RA, et al. 2019. Mol Med. 25:01:00. PubMed
  395. Jain A, et al. 2020. Nat Immunol. 0.920138889. PubMed
  396. Nakamura K, et al. 2018. Cancer Cell. 33:634. PubMed
  397. Smith LK, et al. 2021. Elife. 10:. PubMed
  398. Schmit T, et al. 2022. Cell Rep. 38:110456. PubMed
  399. Lee GR, et al. 2021. JCI Insight. 6:. PubMed
  400. Chen J, et al. 2014. Cell Res. 24:1050. PubMed
  401. Xu Y, et al. 2014. Proc Natl Acad Sci U S A. 111:6371. PubMed
  402. Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
  403. Lee EKS, et al. 2018. Cell Host Microbe. 23:121. PubMed
  404. Dyer DP et al. 2019. Immunity. 50(2):378-389 . PubMed
  405. Orr MT, et al. 2019. NPJ Vaccines. 4:1. PubMed
  406. Geng S, et al. 2019. Sci Adv. 5:eaav2309. PubMed
  407. Rappe JCF, et al. 2021. J Exp Med. 218:. PubMed
  408. Rivera CA, et al. 2022. Immunity. 55:129. PubMed
  409. Awida Z, et al. 2021. Int J Mol Sci. 23:. PubMed
  410. Caporarello N, et al. 2022. Nat Commun. 13:4170. PubMed
  411. Zhang H, et al. 2022. Commun Biol. 5:916. PubMed
  412. Stadtmann A, et al. 2015. J Immunol. 195: 1152-1161. PubMed
  413. Jia H, et al. 2016. J Immunol. 197: 859 - 871. PubMed
  414. Heyde A, et al. 2021. Cell. 184(5):1348-1361.e22. PubMed
  415. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  416. Tian T, et al. 2020. Cancer Immunol Res. 660:8. PubMed
  417. Buschor S, et al. 2017. PLoS Pathogens. 13(6):e1006476. PubMed
  418. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  419. Aggarwal N, et al. 2021. Cell Rep. 37:110170. PubMed
  420. Chuang LT, et al. 2021. Molecules. 26:. PubMed
  421. Singh N, et al. 2016. Dis Model Mech. 9: 885 - 897. PubMed
  422. Cojohari O, Peppenelli M, Chan G 2016. Blood. 128: 529 - 541. PubMed
RRID
AB_1236494 (BioLegend Cat. No. 127606)
AB_1236488 (BioLegend Cat. No. 127605)

Antigen Details

Structure
A 21-35 kD GPI-anchorded membrane protein
Distribution

Expressed on the majority of myeloid cells in bone marrow and peripheral granulocytes. The monoclonal antibody RB6-8C5 recognizes both Ly-6G and Ly-6C.

Cell Type
Granulocytes, Macrophages, Monocytes
Biology Area
Immunology, Innate Immunity
Antigen References

Fleming TJ, et al. 1993. J. Immunol. 151:2399.

Gene ID
546644 View all products for this Gene ID
UniProt
View information about Ly-6G on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All Ly-6G Reagents Request Custom Conjugation
Description Clone Applications
Purified anti-mouse Ly-6G (Maxpar® Ready) 1A8 FC,CyTOF®,WB
Brilliant Violet 650™ anti-mouse Ly-6G 1A8 FC
Brilliant Violet 711™ anti-mouse Ly-6G 1A8 FC
Brilliant Violet 605™ anti-mouse Ly-6G 1A8 FC
Brilliant Violet 785™ anti-mouse Ly-6G 1A8 FC
PE/Dazzle™ 594 anti-mouse Ly-6G 1A8 FC
APC/Fire™ 750 anti-mouse Ly-6G 1A8 FC
PerCP anti-mouse Ly-6G 1A8 FC
TotalSeq™-A0015 anti-mouse Ly-6G 1A8 PG
TotalSeq™-B0015 anti-mouse Ly-6G 1A8 PG
TotalSeq™-C0015 anti-mouse Ly-6G 1A8 PG
Spark Blue™ 550 anti-mouse Ly-6G 1A8 FC
Spark NIR™ 685 anti-mouse Ly-6G 1A8 FC
Alexa Fluor® 594 anti-mouse Ly-6G 1A8 IHC-F,SB
Purified anti-mouse Ly-6G 1A8 FC,IHC-F,IHC-P,SB
Biotin anti-mouse Ly-6G 1A8 FC,IHC
FITC anti-mouse Ly-6G 1A8 FC
PE anti-mouse Ly-6G 1A8 FC
Alexa Fluor® 647 anti-mouse Ly-6G 1A8 FC,IHC-F,SB
Pacific Blue™ anti-mouse Ly-6G 1A8 FC
APC anti-mouse Ly-6G 1A8 FC
PerCP/Cyanine5.5 anti-mouse Ly-6G 1A8 FC
PE/Cyanine7 anti-mouse Ly-6G 1A8 FC
Alexa Fluor® 700 anti-mouse Ly-6G 1A8 FC,IHC
APC/Cyanine7 anti-mouse Ly-6G 1A8 FC
Alexa Fluor® 488 anti-mouse Ly-6G 1A8 FC,IHC-F,SB
Brilliant Violet 421™ anti-mouse Ly-6G 1A8 FC,IHC-F
Brilliant Violet 570™ anti-mouse Ly-6G 1A8 FC
Ultra-LEAF™ Purified anti-mouse Ly-6G 1A8 FC,Depletion,IHC
Brilliant Violet 510™ anti-mouse Ly-6G 1A8 FC
Spark YG™ 593 anti-mouse Ly-6G 1A8 FC
APC/Fire™ 810 anti-mouse Ly-6G Antibody 1A8 FC
PE/Cyanine5 anti-mouse Ly-6G 1A8 FC
PE/Fire™ 810 anti-mouse Ly-6G Antibody 1A8 FC
PE/Fire™ 640 anti-mouse Ly-6G 1A8 FC
Spark YG™ 570 anti-mouse Ly-6G 1A8 IHC-F,FC
Spark UV™ 387 anti-mouse Ly-6G 1A8 FC
Spark Red™ 718 anti-mouse Ly-6G (Flexi-Fluor™) 1A8 FC
Spark Blue™ 574 anti-mouse Ly-6G (Flexi-Fluor™) 1A8 FC
PerCP/Fire™ 806 anti-mouse Ly-6G 1A8 FC
StarBright UltraViolet 575 anti-mouse Ly-6G 1A8 FC
Go To Top Version: 3    Revision Date: 01-06-2017

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Pricing & Availability
Clone
1A8 (See other available formats)
Regulatory Status
RUO
Other Names
Lymphocyte antigen 6 complex, locus G
Isotype
Rat IgG2a, κ
Ave. Rating
Submit a Review
Product Citations
publications
1A8_FITC_082808.jpg
BALB/cmouse bone marrow cells stained with 1A8 FITC (gated on myeloid cells)
  • 1A8_FITC_082808.jpg
    BALB/cmouse bone marrow cells stained with 1A8 FITC (gated on myeloid cells)
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability Save
127606 500 µg SEK2201
Check Availability


Need larger quantities of this item?
Request Bulk Quote
127605 50 µg SEK748
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

Lymphocyte antigen 6 complex, locus G (Ly-6G), a 21-25 kD GPI-anchored protein, is expressed on the majority of myeloid cells in bone marrow and peripheral granulocytes.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Ly-6G transfected EL-4J cell line.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for other applications.

Excitation Laser
Blue Laser (488 nm)
Application Notes

While 1A8 recognizes only Ly-6G, clone RB6-8C5 recognizes both Ly-6G and Ly-6C. Clone RB6-8C5 binds with high affinity to mouse Ly-6G molecules and to a lower extent to Ly-6C15. Clone RB6-8C5 impairs the binding of anti-mouse Ly-6G clone 1A815. However, clone RB6-8C5 is able to stain in the presence of anti-mouse Ly-6C clone HK1.416.

Additional reported applications (for the relevant formats) include: immunohistochemistry9 of frozen sections10 and paraffin-embedded sections11, depletion4, 12-14, and spatial biology (IBEX)20,21. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for in vivo studies or highly sensitive assays (Cat. No. 127632, 127649, 127650, 127661 and 127662).

Application References
  1. Fleming TJ, et al. 1993. J. Immunol. 151:2399. (FC)
  2. Daley JM, et al. 2008. J. Leukocyte Biol. 83:1. (FC)
  3. Dietlin TA, et al. 2007. J. Leukocyte Biol. 81:1205. (FC)
  4. Daley J, et al. 2007. J. Leukocyte Biol. doi:10.1189. (Deplete) PubMed
  5. Tadagavadi RK, et al. 2010. J. Immunol. 185:4904. PubMed
  6. Sumagin R, et al. 2010. J. Immunol. 185:7057. PubMed
  7. Guiducci C, et al. 2010. J. Exp Med. 207:2931. PubMed
  8. Fujita M, et al. 2011. Cancer Res. 71:2664. PubMed
  9. Van Leeuwen, et al. 2008. Arterioscler. Thromb. Vasc. Biol. 28:84. (IHC)
  10. Kowanetz M, et al. 2010. P. Natl. Acad. Sci. USA 107:21248. [supplementary data] (IHC)
  11. Esbona K, et al. 2016. Breast Cancer Res. 18:35. (IHC)
  12. Wojtasiak M, et al. 2010. J. Gen. Virol. 91:2158. (FC, Deplete)
  13. Jaeger BN, et al. 2012. J. Exp. Med. 209:565. (Deplete)
  14. Wozniak KL, et al. 2012. BMC Immunol. 13:65 (FC, Deplete)
  15. Ribechini E, et al. 2009. Eur. J. Immunol. 39:3538.
  16. Ng LG, et al. 2011. J Invest. Dermatol. 131:2058. PubMed
  17. Ma C, et al. 2012. J. Leukoc. Biol. 92:1199.
  18. McCartney-Francis, N, et al. 2014. J Leukoc. Biol. 96:917. PubMed
  19. Her Z, et al. 2014. EMBO Mol. Med. 7:24. PubMed
  20. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  21. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Frieler RA, et al. 2017. Exp Neurol. 298:104. PubMed
  2. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  3. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  4. Gordan S, et al. 2020. Cell Reports. 29(10):3033-3046.e4.. PubMed
  5. Pohlmeier L, et al. 2021. Allergy. 76:2030. PubMed
  6. Li T, et al. 2022. J Exp Med. 219: . PubMed
  7. Yang Y, et al. 2022. FEBS J. 289:5279. PubMed
  8. Yue Y, et al. 2022. Nat Biomed Eng. 6:898. PubMed
  9. Zhu Y, et al. 2023. J Ethnopharmacol. 301:115763. PubMed
  10. Xu Y, et al. 2023. EMBO Rep. 24:e55503. PubMed
  11. Xu H, et al. 2022. Aging Dis. 13:1875. PubMed
  12. Pavliuchenko N, et al. 2023. Front Immunol. 13:1035226. PubMed
  13. Tsioti I, et al. 2023. J Neuroinflammation. 20:25. PubMed
  14. Zong P, et al. 2022. Nat Cardiovasc Res. 1:344. PubMed
  15. Sanmarco LM, et al. 2022. Nature. 611:801. PubMed
  16. Peng J, et al. 2023. Am J Reprod Immunol. 89:e13678. PubMed
  17. Le DT, et al. 2023. iScience. 26:106059. PubMed
  18. Veras FP, et al. 2023. Respir Res. 24:66. PubMed
  19. Doke T, et al. 2023. Nat Metab. 5:414. PubMed
  20. Tang C, et al. 2023. Nat Commun. 14:1493. PubMed
  21. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  22. Ma X, et al. 2023. Nat Commun. 14:1606. PubMed
  23. Park JA, et al. 2023. J Immunother Cancer. 11:. PubMed
  24. Chung JY, et al. 2023. Nat Commun. 14:1794. PubMed
  25. Zhu CL, et al. 2023. Int J Biol Sci. 19:1413. PubMed
  26. Silva BM, et al. 2023. J Clin Invest. 133:. PubMed
  27. Cui B, et al. 2023. Int Immunopharmacol. 120:110240. PubMed
  28. Oh J, et al. 2023. Nat Commun. 14:3278. PubMed
  29. Valladao A, et al. 2016. J Immunol. 197(12):4541-4551. PubMed
  30. Campbell IK, Leong D 2016. J Immunol. 197(11):4392-4402. PubMed
  31. Sun L, et al. 2021. Cancer Cell. 39:1361. PubMed
  32. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  33. He R, et al. 2021. J Immunol. 206:2353. PubMed
  34. Lefebvre MN, et al. 2021. Cell Rep. 37:109956. PubMed
  35. Suresh R, et al. 2020. J Immunother Cancer. 8:. PubMed
  36. Okajima T, et al. 2021. Front Immunol. 12:738041. PubMed
  37. Tripathi H, et al. 2020. J Mol Cell Cardiol. 149:95. PubMed
  38. Kim S, et al. 2020. Immunity. 53(4):759-774.e9. PubMed
  39. Garcia-Fabiani MB, et al. 2020. Methods Enzymol. 632:369. PubMed
  40. Miller CM, et al. 2020. J Virol. 94:00:00. PubMed
  41. Long M, et al. 2017. J Immunol. 198(2):862-872. PubMed
  42. Oliveira-Lima OC, et al. 2015. Immunobiology. . PubMed
  43. Mandraju R, et al. 2014. J Immunol. 192:4303. PubMed
  44. Patsalos A, et al. 2019. J Immunol. 203:1532. PubMed
  45. Lin R, et al. 2020. Sci Rep. 10:14397. PubMed
  46. Yang C, et al. 2021. J Immunother Cancer. 9:. PubMed
  47. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  48. Johnson KD, et al. 2022. Blood Adv. 6:1464. PubMed
  49. Clark K, et al. 2015. J Autoimmun. Available online 21 August 2015. PubMed
  50. Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
  51. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  52. Huai W, et al. 2019. J Exp Med. 216:772. PubMed
  53. Han J, et al. 2022. FEBS J. 289:417. PubMed
  54. Larsen SE, et al. 2021. Sci Rep. 11:9040. PubMed
  55. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  56. Torre S, et al. 2016. Nat Immunol. 10.1038/ni.3581. PubMed
  57. Montufar-Solis D, Klein J 2016. PLoS One. 11: 014611. PubMed
  58. Wang C, et al. 2015. Sci Rep. 5: 14124. PubMed
  59. Park JA, et al. 2021. J Hematol Oncol. 14:142. PubMed
  60. Bae SH, et al. 2021. Theranostics. 11:2522. PubMed
  61. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  62. Mitsune A, et al. 2021. Respir Res. 22:232. PubMed
  63. Castiglioni A, et al. 2015. PLoS One. 10:128094. PubMed
  64. Guesdon W, et al. 2015. J Infect Dis. 212: 1332 - 1340. PubMed
  65. Strother R, et al. 2016. J Immunol. 197(11):4301-4311. PubMed
  66. Rao S, et al. 2017. Cell. 168(3):503-516.e12. PubMed
  67. LeBlond ND, et al. 2020. J Lipid Res. 61:1697. PubMed
  68. Fujikura D, et al. 2013. PLoS One. 8:e55321. PubMed
  69. Ueki H, et al. 2020. Nat Protoc. 15:1041. PubMed
  70. Saika A, et al. 2020. FASEB Bioadv. 2:59. PubMed
  71. Nguyen CM, et al. 2019. Diabetes. 68:1499. PubMed
  72. Wang H et al. 2017. Developmental cell. 40(6):566-582 . PubMed
  73. Pan W et al. 2017. Immunity. 47(2):284-297 . PubMed
  74. Billi AC, et al. 2019. JCI Insight. 4:8. PubMed
  75. Han YH, et al. 2021. Science. 373:. PubMed
  76. Dieterich LC, et al. 2019. International Journal of Cancer. 145(10):2804-2815. PubMed
  77. Diao N, et al. 2016. Sci Rep. 6:34672. PubMed
  78. Ellis G, et al. 2015. EMBO Rep. 16: 1203-1218. PubMed
  79. Wang L, et al. 2017. Front Immunol.. 10.3389/fimmu.2017.01754. PubMed
  80. Luan HH et al. 2019. Cell. 178(5):1231-1244 . PubMed
  81. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  82. Wu X, et al. 2021. Elife. 10:. PubMed
  83. Opzoomer JW, et al. 2021. Sci Adv. 7:eabg9518. PubMed
  84. Abad C, et al. 2014. J Leukoc Biol. 95:357. PubMed
  85. Syed A, et al. 2015. Infect Immun . 83: 3428-3437. PubMed
  86. Liu Z, et al. 2016. J Biol Chem. 291: 1441 - 1447. PubMed
  87. Ratitong B, et al. 2021. Cell Reports. 35(7):109139. PubMed
  88. Na YR, et al. 2020. Cell Rep. 107643:31. PubMed
  89. Cheng K, et al. 2021. Nat Commun. 12:2041. PubMed
  90. Kotfis K, et al. 2020. British Journal of Pharmacology. 49(1):66-72. PubMed
  91. Jin RM, et al. 2017. J Immunol. 198:352. PubMed
  92. Xiao P, et al. 2019. J Exp Med. 216:337. PubMed
  93. Lagares D, et al. 2017. Sci Transl Med. 9:eaal3765. PubMed
  94. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  95. Kimball AS et al. 2019. Immunity. 51(2):258-271 . PubMed
  96. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  97. Aegerter H, et al. 2020. Nat Immunol. 0.975694444. PubMed
  98. Jacome-Galarza C, et al. 2011. J Bone Miner Res. 26:1207. PubMed
  99. Huixin Xu et al. 2018. EMBO molecular medicine. 10(9) pii: e8931. PubMed
  100. Geng S, et al. 2021. JCI Insight. 6:. PubMed
  101. Synn CB, et al. 2022. Clin Transl Immunology. 11:e1364. PubMed
  102. Morales-Mantilla DE, et al. 2022. Elife. 11:. PubMed
  103. Chen M, et al. 2021. Oncol Lett. 21:435. PubMed
  104. Minogue A, et al. 2014. Neurobiol Aging. 35:1442. PubMed
  105. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  106. Zheng J, et al. 2020. bioRxiv. . PubMed
  107. Mao FY, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:395. PubMed
  108. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  109. Patel S, et al. 2019. Viruses. 0.877083333. PubMed
  110. Mishra BB, et al. 2017. Nat Microbiol. 2:17072. PubMed
  111. Roy K, et al. 2019. Immunity. 50:616. PubMed
  112. Bradley KC, et al. 2019. Cell Rep. 28:245. PubMed
  113. Christ A, et al. 2018. Cell. 172:162. PubMed
  114. Zhao X, et al. 2022. Nat Protoc. 17:2240. PubMed
  115. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  116. Elahi S, et al. 2020. Stem Cell Res. 43:101710. PubMed
  117. Gousopoulos E, et al. 2016. Am J Pathol. 186:2193-2203. PubMed
  118. Radjabova V, et al. 2015. J Immunol. 195: 3149 - 3159. PubMed
  119. Li Z, et al. 2018. Front Immunol. 9:347. PubMed
  120. He J, et al. 2019. J Clin Invest. 130. PubMed
  121. Yu L, et al. 2019. Elife. 8:e46677. PubMed
  122. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  123. Shen M, et al. 2022. Nat Cancer. 3:60. PubMed
  124. Flögel U, et al. 2021. Nat Commun. 12:5847. PubMed
  125. Wu M, et al. 2013. Proc Natl Acad Sci U S A. 110:9439. PubMed
  126. Weinheimer-Haus E, et al. 2014. PLoS One. 9:91355. PubMed
  127. Ericson J, et al. 2014. PLoS One. 9:108553. PubMed
  128. Shih Y, et al. 2015. JPEN J Parenter Enteral Nutr. . PubMed
  129. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  130. Fischer KJ, et al. 2019. J Immunol. 202:2027. PubMed
  131. Challa TD, et al. 2020. Cell Reports. 30(10):3424-3433. PubMed
  132. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  133. Uderhardt S, et al. 2019. Cell. 177:541. PubMed
  134. Hermetet F, et al. 2019. Nat Commun. 10:523. PubMed
  135. Nagatake T, et al. 2018. Int Immunol. 30:471. PubMed
  136. Shevchenko MA, et al. 2018. J Immunol Res. 8:53. PubMed
  137. Covarrubias AJ, et al. 2020. Nat Metab. 1265:2. PubMed
  138. Zheng J, et al. 2020. Nature. . PubMed
  139. Kim P, et al. 2015. Infect Immun . 83: 2992 - 3002. PubMed
  140. Robinett RA et al. 2018. Cell systems. 7(1):41-48 . PubMed
  141. Rebecca S Dickinson et al. 2017. Wellcome open research. 0.155555556 . PubMed
  142. Simpson K, et al. 2012. J Immunol. 189:5533. PubMed
  143. Nuro-Gyina PK, et al. 2021. J Immunol. 207:868. PubMed
  144. Zeng Q, et al. 2022. iScience. 25:105151. PubMed
  145. Giampazolias E, et al. 2021. Cell. . PubMed
  146. Prizant H, et al. 2021. Cell Reports. 36:109523. PubMed
  147. Xu P, et al. 2020. Cancer Immunol Res. 8:1193. PubMed
  148. Winchell CG, et al. 2020. Front Immunol. 1.077083333. PubMed
  149. Li YT, et al. 2019. Elife. 8:e47642. PubMed
  150. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  151. Nagatake T, et al. 2018. J Allergy Clin Immunol. 142:470. PubMed
  152. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  153. Qin W, et al. 2022. Bio Protoc. 12:e4287. PubMed
  154. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  155. Shibuya M, et al. 2021. iScience. 24:103131. PubMed
  156. Taya M, et al. 2020. Endocr Relat Cancer. 27:261. PubMed
  157. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  158. Xu G, et al. 2020. Cell Rep. 32:108170. PubMed
  159. Thomas DG et al. 2018. Cell reports. 25(13):3774-3785 . PubMed
  160. Lai SM et al. 2018. Cell reports. 25(11):3099-3109 . PubMed
  161. Chen ST et al. 2019. Cell host & microbe. 25(4):602-616 . PubMed
  162. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  163. Makino A, et al. 2021. iScience. 24:103201. PubMed
  164. Gao Z, et al. 2022. J Inflamm Res. 15:3337. PubMed
  165. Njock MS, et al. 2022. J Extracell Vesicles. 11:e12228. PubMed
  166. Gorina R, et al. 2014. J Immunol. 192:324. PubMed
  167. Nacer A, et al. 2014. PLoS Pathog. 10:1004528. PubMed
  168. Gamradt P, et al. 2016. PLoS Pathog. 12:e1006032. PubMed
  169. Varikuti S, et al. 2020. Br J Cancer. 122:1005. PubMed
  170. Cartwright ANR, et al. 2021. Cancer Immunol Res. 9:470. PubMed
  171. LeBlond ND, et al. 2020. J Lipid Res. 61:1697. PubMed
  172. Zhu YP et al. 2018. Cell reports. 24(9):2329-2341 . PubMed
  173. van Geffen C, et al. 2021. Front Immunol. 12:695933. PubMed
  174. Gu H, et al. 2021. Elife. 10:. PubMed
  175. Issah Y, et al. 2021. Elife. 10:. PubMed
  176. Wei Y, et al. 2021. Endocrinology. 162(8):. PubMed
  177. Asadi Shahmirzadi A, et al. 2020. Cell Metabolism. 32(3):447-456.e6. PubMed
  178. Xu C, et al. 2020. Immunity. 53(2):417-428.e4. PubMed
  179. Sparber F, et al. 2019. Cell Host Microbe. 25:389. PubMed
  180. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  181. Gong P, et al. 2022. Cell Death Discov. 8:466. PubMed
  182. Danzer H, et al. 2020. Elife. 9:00. PubMed
  183. Willemze RA, et al. 2019. Mol Med. 25:01:00. PubMed
  184. Jain A, et al. 2020. Nat Immunol. 0.920138889. PubMed
  185. Nakamura K, et al. 2018. Cancer Cell. 33:634. PubMed
  186. Smith LK, et al. 2021. Elife. 10:. PubMed
  187. Schmit T, et al. 2022. Cell Rep. 38:110456. PubMed
  188. Lee GR, et al. 2021. JCI Insight. 6:. PubMed
  189. Chen J, et al. 2014. Cell Res. 24:1050. PubMed
  190. Xu Y, et al. 2014. Proc Natl Acad Sci U S A. 111:6371. PubMed
  191. Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
  192. Lee EKS, et al. 2018. Cell Host Microbe. 23:121. PubMed
  193. Dyer DP et al. 2019. Immunity. 50(2):378-389 . PubMed
  194. Orr MT, et al. 2019. NPJ Vaccines. 4:1. PubMed
  195. Geng S, et al. 2019. Sci Adv. 5:eaav2309. PubMed
  196. Rappe JCF, et al. 2021. J Exp Med. 218:. PubMed
  197. Rivera CA, et al. 2022. Immunity. 55:129. PubMed
  198. Awida Z, et al. 2021. Int J Mol Sci. 23:. PubMed
  199. Caporarello N, et al. 2022. Nat Commun. 13:4170. PubMed
  200. Zhang H, et al. 2022. Commun Biol. 5:916. PubMed
  201. Stadtmann A, et al. 2015. J Immunol. 195: 1152-1161. PubMed
  202. Jia H, et al. 2016. J Immunol. 197: 859 - 871. PubMed
  203. Heyde A, et al. 2021. Cell. 184(5):1348-1361.e22. PubMed
  204. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  205. Tian T, et al. 2020. Cancer Immunol Res. 660:8. PubMed
  206. Buschor S, et al. 2017. PLoS Pathogens. 13(6):e1006476. PubMed
  207. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  208. Aggarwal N, et al. 2021. Cell Rep. 37:110170. PubMed
  209. Chuang LT, et al. 2021. Molecules. 26:. PubMed
  210. Singh N, et al. 2016. Dis Model Mech. 9: 885 - 897. PubMed
  211. Cojohari O, Peppenelli M, Chan G 2016. Blood. 128: 529 - 541. PubMed
  212. Frieler RA, et al. 2017. Exp Neurol. 298:104. PubMed
  213. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  214. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  215. Gordan S, et al. 2020. Cell Reports. 29(10):3033-3046.e4.. PubMed
  216. Pohlmeier L, et al. 2021. Allergy. 76:2030. PubMed
  217. Li T, et al. 2022. J Exp Med. 219: . PubMed
  218. Yang Y, et al. 2022. FEBS J. 289:5279. PubMed
  219. Yue Y, et al. 2022. Nat Biomed Eng. 6:898. PubMed
  220. Zhu Y, et al. 2023. J Ethnopharmacol. 301:115763. PubMed
  221. Xu Y, et al. 2023. EMBO Rep. 24:e55503. PubMed
  222. Xu H, et al. 2022. Aging Dis. 13:1875. PubMed
  223. Pavliuchenko N, et al. 2023. Front Immunol. 13:1035226. PubMed
  224. Tsioti I, et al. 2023. J Neuroinflammation. 20:25. PubMed
  225. Zong P, et al. 2022. Nat Cardiovasc Res. 1:344. PubMed
  226. Sanmarco LM, et al. 2022. Nature. 611:801. PubMed
  227. Peng J, et al. 2023. Am J Reprod Immunol. 89:e13678. PubMed
  228. Le DT, et al. 2023. iScience. 26:106059. PubMed
  229. Veras FP, et al. 2023. Respir Res. 24:66. PubMed
  230. Doke T, et al. 2023. Nat Metab. 5:414. PubMed
  231. Tang C, et al. 2023. Nat Commun. 14:1493. PubMed
  232. Senatus L, et al. 2023. Commun Biol. 6:280. PubMed
  233. Ma X, et al. 2023. Nat Commun. 14:1606. PubMed
  234. Park JA, et al. 2023. J Immunother Cancer. 11:. PubMed
  235. Chung JY, et al. 2023. Nat Commun. 14:1794. PubMed
  236. Zhu CL, et al. 2023. Int J Biol Sci. 19:1413. PubMed
  237. Silva BM, et al. 2023. J Clin Invest. 133:. PubMed
  238. Cui B, et al. 2023. Int Immunopharmacol. 120:110240. PubMed
  239. Oh J, et al. 2023. Nat Commun. 14:3278. PubMed
  240. Valladao A, et al. 2016. J Immunol. 197(12):4541-4551. PubMed
  241. Campbell IK, Leong D 2016. J Immunol. 197(11):4392-4402. PubMed
  242. Sun L, et al. 2021. Cancer Cell. 39:1361. PubMed
  243. Golden GJ, et al. 2021. MBio. 12:e0118121. PubMed
  244. He R, et al. 2021. J Immunol. 206:2353. PubMed
  245. Lefebvre MN, et al. 2021. Cell Rep. 37:109956. PubMed
  246. Suresh R, et al. 2020. J Immunother Cancer. 8:. PubMed
  247. Okajima T, et al. 2021. Front Immunol. 12:738041. PubMed
  248. Tripathi H, et al. 2020. J Mol Cell Cardiol. 149:95. PubMed
  249. Kim S, et al. 2020. Immunity. 53(4):759-774.e9. PubMed
  250. Garcia-Fabiani MB, et al. 2020. Methods Enzymol. 632:369. PubMed
  251. Miller CM, et al. 2020. J Virol. 94:00:00. PubMed
  252. Long M, et al. 2017. J Immunol. 198(2):862-872. PubMed
  253. Oliveira-Lima OC, et al. 2015. Immunobiology. . PubMed
  254. Mandraju R, et al. 2014. J Immunol. 192:4303. PubMed
  255. Patsalos A, et al. 2019. J Immunol. 203:1532. PubMed
  256. Lin R, et al. 2020. Sci Rep. 10:14397. PubMed
  257. Yang C, et al. 2021. J Immunother Cancer. 9:. PubMed
  258. Jiang W, et al. 2021. Oncol Lett. 22:625. PubMed
  259. Johnson KD, et al. 2022. Blood Adv. 6:1464. PubMed
  260. Clark K, et al. 2015. J Autoimmun. Available online 21 August 2015. PubMed
  261. Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
  262. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  263. Huai W, et al. 2019. J Exp Med. 216:772. PubMed
  264. Han J, et al. 2022. FEBS J. 289:417. PubMed
  265. Larsen SE, et al. 2021. Sci Rep. 11:9040. PubMed
  266. Jenull S, et al. 2021. Cell Reports. 36(3):109406. PubMed
  267. Torre S, et al. 2016. Nat Immunol. 10.1038/ni.3581. PubMed
  268. Montufar-Solis D, Klein J 2016. PLoS One. 11: 014611. PubMed
  269. Wang C, et al. 2015. Sci Rep. 5: 14124. PubMed
  270. Park JA, et al. 2021. J Hematol Oncol. 14:142. PubMed
  271. Bae SH, et al. 2021. Theranostics. 11:2522. PubMed
  272. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  273. Mitsune A, et al. 2021. Respir Res. 22:232. PubMed
  274. Castiglioni A, et al. 2015. PLoS One. 10:128094. PubMed
  275. Guesdon W, et al. 2015. J Infect Dis. 212: 1332 - 1340. PubMed
  276. Strother R, et al. 2016. J Immunol. 197(11):4301-4311. PubMed
  277. Rao S, et al. 2017. Cell. 168(3):503-516.e12. PubMed
  278. LeBlond ND, et al. 2020. J Lipid Res. 61:1697. PubMed
  279. Fujikura D, et al. 2013. PLoS One. 8:e55321. PubMed
  280. Ueki H, et al. 2020. Nat Protoc. 15:1041. PubMed
  281. Saika A, et al. 2020. FASEB Bioadv. 2:59. PubMed
  282. Nguyen CM, et al. 2019. Diabetes. 68:1499. PubMed
  283. Wang H et al. 2017. Developmental cell. 40(6):566-582 . PubMed
  284. Pan W et al. 2017. Immunity. 47(2):284-297 . PubMed
  285. Billi AC, et al. 2019. JCI Insight. 4:8. PubMed
  286. Han YH, et al. 2021. Science. 373:. PubMed
  287. Dieterich LC, et al. 2019. International Journal of Cancer. 145(10):2804-2815. PubMed
  288. Diao N, et al. 2016. Sci Rep. 6:34672. PubMed
  289. Ellis G, et al. 2015. EMBO Rep. 16: 1203-1218. PubMed
  290. Wang L, et al. 2017. Front Immunol.. 10.3389/fimmu.2017.01754. PubMed
  291. Luan HH et al. 2019. Cell. 178(5):1231-1244 . PubMed
  292. Enriquez AB, et al. 2022. iScience. 25:104305. PubMed
  293. Wu X, et al. 2021. Elife. 10:. PubMed
  294. Opzoomer JW, et al. 2021. Sci Adv. 7:eabg9518. PubMed
  295. Abad C, et al. 2014. J Leukoc Biol. 95:357. PubMed
  296. Syed A, et al. 2015. Infect Immun . 83: 3428-3437. PubMed
  297. Liu Z, et al. 2016. J Biol Chem. 291: 1441 - 1447. PubMed
  298. Ratitong B, et al. 2021. Cell Reports. 35(7):109139. PubMed
  299. Na YR, et al. 2020. Cell Rep. 107643:31. PubMed
  300. Cheng K, et al. 2021. Nat Commun. 12:2041. PubMed
  301. Kotfis K, et al. 2020. British Journal of Pharmacology. 49(1):66-72. PubMed
  302. Jin RM, et al. 2017. J Immunol. 198:352. PubMed
  303. Xiao P, et al. 2019. J Exp Med. 216:337. PubMed
  304. Lagares D, et al. 2017. Sci Transl Med. 9:eaal3765. PubMed
  305. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  306. Kimball AS et al. 2019. Immunity. 51(2):258-271 . PubMed
  307. Korangath P, et al. 2020. Bio Protoc. 10:e3822. PubMed
  308. Aegerter H, et al. 2020. Nat Immunol. 0.975694444. PubMed
  309. Jacome-Galarza C, et al. 2011. J Bone Miner Res. 26:1207. PubMed
  310. Huixin Xu et al. 2018. EMBO molecular medicine. 10(9) pii: e8931. PubMed
  311. Geng S, et al. 2021. JCI Insight. 6:. PubMed
  312. Synn CB, et al. 2022. Clin Transl Immunology. 11:e1364. PubMed
  313. Morales-Mantilla DE, et al. 2022. Elife. 11:. PubMed
  314. Chen M, et al. 2021. Oncol Lett. 21:435. PubMed
  315. Minogue A, et al. 2014. Neurobiol Aging. 35:1442. PubMed
  316. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  317. Zheng J, et al. 2020. bioRxiv. . PubMed
  318. Mao FY, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:395. PubMed
  319. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  320. Patel S, et al. 2019. Viruses. 0.877083333. PubMed
  321. Mishra BB, et al. 2017. Nat Microbiol. 2:17072. PubMed
  322. Roy K, et al. 2019. Immunity. 50:616. PubMed
  323. Bradley KC, et al. 2019. Cell Rep. 28:245. PubMed
  324. Christ A, et al. 2018. Cell. 172:162. PubMed
  325. Zhao X, et al. 2022. Nat Protoc. 17:2240. PubMed
  326. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  327. Elahi S, et al. 2020. Stem Cell Res. 43:101710. PubMed
  328. Gousopoulos E, et al. 2016. Am J Pathol. 186:2193-2203. PubMed
  329. Radjabova V, et al. 2015. J Immunol. 195: 3149 - 3159. PubMed
  330. Li Z, et al. 2018. Front Immunol. 9:347. PubMed
  331. He J, et al. 2019. J Clin Invest. 130. PubMed
  332. Yu L, et al. 2019. Elife. 8:e46677. PubMed
  333. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  334. Shen M, et al. 2022. Nat Cancer. 3:60. PubMed
  335. Flögel U, et al. 2021. Nat Commun. 12:5847. PubMed
  336. Wu M, et al. 2013. Proc Natl Acad Sci U S A. 110:9439. PubMed
  337. Weinheimer-Haus E, et al. 2014. PLoS One. 9:91355. PubMed
  338. Ericson J, et al. 2014. PLoS One. 9:108553. PubMed
  339. Shih Y, et al. 2015. JPEN J Parenter Enteral Nutr. . PubMed
  340. Deerhake ME, et al. 2021. Immunity. 54(3):484-498.e8. PubMed
  341. Fischer KJ, et al. 2019. J Immunol. 202:2027. PubMed
  342. Challa TD, et al. 2020. Cell Reports. 30(10):3424-3433. PubMed
  343. Liu C et al. 2019. Immunity. 51(2):381-397 . PubMed
  344. Uderhardt S, et al. 2019. Cell. 177:541. PubMed
  345. Hermetet F, et al. 2019. Nat Commun. 10:523. PubMed
  346. Nagatake T, et al. 2018. Int Immunol. 30:471. PubMed
  347. Shevchenko MA, et al. 2018. J Immunol Res. 8:53. PubMed
  348. Covarrubias AJ, et al. 2020. Nat Metab. 1265:2. PubMed
  349. Zheng J, et al. 2020. Nature. . PubMed
  350. Kim P, et al. 2015. Infect Immun . 83: 2992 - 3002. PubMed
  351. Robinett RA et al. 2018. Cell systems. 7(1):41-48 . PubMed
  352. Rebecca S Dickinson et al. 2017. Wellcome open research. 0.155555556 . PubMed
  353. Simpson K, et al. 2012. J Immunol. 189:5533. PubMed
  354. Nuro-Gyina PK, et al. 2021. J Immunol. 207:868. PubMed
  355. Zeng Q, et al. 2022. iScience. 25:105151. PubMed
  356. Giampazolias E, et al. 2021. Cell. . PubMed
  357. Prizant H, et al. 2021. Cell Reports. 36:109523. PubMed
  358. Xu P, et al. 2020. Cancer Immunol Res. 8:1193. PubMed
  359. Winchell CG, et al. 2020. Front Immunol. 1.077083333. PubMed
  360. Li YT, et al. 2019. Elife. 8:e47642. PubMed
  361. Xueyang Yu et al. 2017. Immunity. 47(5):903-912 . PubMed
  362. Nagatake T, et al. 2018. J Allergy Clin Immunol. 142:470. PubMed
  363. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  364. Qin W, et al. 2022. Bio Protoc. 12:e4287. PubMed
  365. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  366. Shibuya M, et al. 2021. iScience. 24:103131. PubMed
  367. Taya M, et al. 2020. Endocr Relat Cancer. 27:261. PubMed
  368. Hirata SI, et al. 2020. Allergy. 75:1939. PubMed
  369. Xu G, et al. 2020. Cell Rep. 32:108170. PubMed
  370. Thomas DG et al. 2018. Cell reports. 25(13):3774-3785 . PubMed
  371. Lai SM et al. 2018. Cell reports. 25(11):3099-3109 . PubMed
  372. Chen ST et al. 2019. Cell host & microbe. 25(4):602-616 . PubMed
  373. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  374. Makino A, et al. 2021. iScience. 24:103201. PubMed
  375. Gao Z, et al. 2022. J Inflamm Res. 15:3337. PubMed
  376. Njock MS, et al. 2022. J Extracell Vesicles. 11:e12228. PubMed
  377. Gorina R, et al. 2014. J Immunol. 192:324. PubMed
  378. Nacer A, et al. 2014. PLoS Pathog. 10:1004528. PubMed
  379. Gamradt P, et al. 2016. PLoS Pathog. 12:e1006032. PubMed
  380. Varikuti S, et al. 2020. Br J Cancer. 122:1005. PubMed
  381. Cartwright ANR, et al. 2021. Cancer Immunol Res. 9:470. PubMed
  382. LeBlond ND, et al. 2020. J Lipid Res. 61:1697. PubMed
  383. Zhu YP et al. 2018. Cell reports. 24(9):2329-2341 . PubMed
  384. van Geffen C, et al. 2021. Front Immunol. 12:695933. PubMed
  385. Gu H, et al. 2021. Elife. 10:. PubMed
  386. Issah Y, et al. 2021. Elife. 10:. PubMed
  387. Wei Y, et al. 2021. Endocrinology. 162(8):. PubMed
  388. Asadi Shahmirzadi A, et al. 2020. Cell Metabolism. 32(3):447-456.e6. PubMed
  389. Xu C, et al. 2020. Immunity. 53(2):417-428.e4. PubMed
  390. Sparber F, et al. 2019. Cell Host Microbe. 25:389. PubMed
  391. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  392. Gong P, et al. 2022. Cell Death Discov. 8:466. PubMed
  393. Danzer H, et al. 2020. Elife. 9:00. PubMed
  394. Willemze RA, et al. 2019. Mol Med. 25:01:00. PubMed
  395. Jain A, et al. 2020. Nat Immunol. 0.920138889. PubMed
  396. Nakamura K, et al. 2018. Cancer Cell. 33:634. PubMed
  397. Smith LK, et al. 2021. Elife. 10:. PubMed
  398. Schmit T, et al. 2022. Cell Rep. 38:110456. PubMed
  399. Lee GR, et al. 2021. JCI Insight. 6:. PubMed
  400. Chen J, et al. 2014. Cell Res. 24:1050. PubMed
  401. Xu Y, et al. 2014. Proc Natl Acad Sci U S A. 111:6371. PubMed
  402. Li Z et al. 2018. Immunity. 49(4):640-653 . PubMed
  403. Lee EKS, et al. 2018. Cell Host Microbe. 23:121. PubMed
  404. Dyer DP et al. 2019. Immunity. 50(2):378-389 . PubMed
  405. Orr MT, et al. 2019. NPJ Vaccines. 4:1. PubMed
  406. Geng S, et al. 2019. Sci Adv. 5:eaav2309. PubMed
  407. Rappe JCF, et al. 2021. J Exp Med. 218:. PubMed
  408. Rivera CA, et al. 2022. Immunity. 55:129. PubMed
  409. Awida Z, et al. 2021. Int J Mol Sci. 23:. PubMed
  410. Caporarello N, et al. 2022. Nat Commun. 13:4170. PubMed
  411. Zhang H, et al. 2022. Commun Biol. 5:916. PubMed
  412. Stadtmann A, et al. 2015. J Immunol. 195: 1152-1161. PubMed
  413. Jia H, et al. 2016. J Immunol. 197: 859 - 871. PubMed
  414. Heyde A, et al. 2021. Cell. 184(5):1348-1361.e22. PubMed
  415. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  416. Tian T, et al. 2020. Cancer Immunol Res. 660:8. PubMed
  417. Buschor S, et al. 2017. PLoS Pathogens. 13(6):e1006476. PubMed
  418. Wang Y, et al. 2022. Nat Cell Biol. 24:230. PubMed
  419. Aggarwal N, et al. 2021. Cell Rep. 37:110170. PubMed
  420. Chuang LT, et al. 2021. Molecules. 26:. PubMed
  421. Singh N, et al. 2016. Dis Model Mech. 9: 885 - 897. PubMed
  422. Cojohari O, Peppenelli M, Chan G 2016. Blood. 128: 529 - 541. PubMed
RRID
AB_1236494 (BioLegend Cat. No. 127606)
AB_1236488 (BioLegend Cat. No. 127605)

Antigen Details

Structure
A 21-35 kD GPI-anchorded membrane protein
Distribution

Expressed on the majority of myeloid cells in bone marrow and peripheral granulocytes. The monoclonal antibody RB6-8C5 recognizes both Ly-6G and Ly-6C.

Cell Type
Granulocytes, Macrophages, Monocytes
Biology Area
Immunology, Innate Immunity
Antigen References

Fleming TJ, et al. 1993. J. Immunol. 151:2399.

Gene ID
546644 View all products for this Gene ID
UniProt
View information about Ly-6G on UniProt.org

Other Formats

View All Ly-6G Reagents Request Custom Conjugation
Description Clone Applications
Purified anti-mouse Ly-6G (Maxpar® Ready) 1A8 FC,CyTOF®,WB
Brilliant Violet 650™ anti-mouse Ly-6G 1A8 FC
Brilliant Violet 711™ anti-mouse Ly-6G 1A8 FC
Brilliant Violet 605™ anti-mouse Ly-6G 1A8 FC
Brilliant Violet 785™ anti-mouse Ly-6G 1A8 FC
PE/Dazzle™ 594 anti-mouse Ly-6G 1A8 FC
APC/Fire™ 750 anti-mouse Ly-6G 1A8 FC
PerCP anti-mouse Ly-6G 1A8 FC
TotalSeq™-A0015 anti-mouse Ly-6G 1A8 PG
TotalSeq™-B0015 anti-mouse Ly-6G 1A8 PG
TotalSeq™-C0015 anti-mouse Ly-6G 1A8 PG
Spark Blue™ 550 anti-mouse Ly-6G 1A8 FC
Spark NIR™ 685 anti-mouse Ly-6G 1A8 FC
Alexa Fluor® 594 anti-mouse Ly-6G 1A8 IHC-F,SB
Purified anti-mouse Ly-6G 1A8 FC,IHC-F,IHC-P,SB
Biotin anti-mouse Ly-6G 1A8 FC,IHC
FITC anti-mouse Ly-6G 1A8 FC
PE anti-mouse Ly-6G 1A8 FC
Alexa Fluor® 647 anti-mouse Ly-6G 1A8 FC,IHC-F,SB
Pacific Blue™ anti-mouse Ly-6G 1A8 FC
APC anti-mouse Ly-6G 1A8 FC
PerCP/Cyanine5.5 anti-mouse Ly-6G 1A8 FC
PE/Cyanine7 anti-mouse Ly-6G 1A8 FC
Alexa Fluor® 700 anti-mouse Ly-6G 1A8 FC,IHC
APC/Cyanine7 anti-mouse Ly-6G 1A8 FC
Alexa Fluor® 488 anti-mouse Ly-6G 1A8 FC,IHC-F,SB
Brilliant Violet 421™ anti-mouse Ly-6G 1A8 FC,IHC-F
Brilliant Violet 570™ anti-mouse Ly-6G 1A8 FC
Ultra-LEAF™ Purified anti-mouse Ly-6G 1A8 FC,Depletion,IHC
Brilliant Violet 510™ anti-mouse Ly-6G 1A8 FC
Spark YG™ 593 anti-mouse Ly-6G 1A8 FC
APC/Fire™ 810 anti-mouse Ly-6G Antibody 1A8 FC
PE/Cyanine5 anti-mouse Ly-6G 1A8 FC
PE/Fire™ 810 anti-mouse Ly-6G Antibody 1A8 FC
PE/Fire™ 640 anti-mouse Ly-6G 1A8 FC
Spark YG™ 570 anti-mouse Ly-6G 1A8 IHC-F,FC
Spark UV™ 387 anti-mouse Ly-6G 1A8 FC
Spark Red™ 718 anti-mouse Ly-6G (Flexi-Fluor™) 1A8 FC
Spark Blue™ 574 anti-mouse Ly-6G (Flexi-Fluor™) 1A8 FC
PerCP/Fire™ 806 anti-mouse Ly-6G 1A8 FC
StarBright UltraViolet 575 anti-mouse Ly-6G 1A8 FC
Go To Top Version: 3    Revision Date: 01-06-2017

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account