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PE anti-human IL-28RA Antibody PE anti-human IL-28RA Antibody

Pricing & Availability
Clone
MHLICR2a (See other available formats)
Regulatory Status
RUO
Other Names
IFNLR1, CRF-2-12, LICR2
Isotype
Mouse IgG2a, κ
Ave. Rating
Submit a Review
Product Citations
publications
MHLICR2a_PE_111708.jpg
Human IL-28RA transfected BW5178 cells stained with MHLICR2a PE.
  • MHLICR2a_PE_111708.jpg
    Human IL-28RA transfected BW5178 cells stained with MHLICR2a PE.
See PE spectral data
Cat # Size Price Quantity Check Availability Save
337804 100 tests SEK2663
Check Availability


Need larger quantities of this item?
Request Bulk Quote
337803 25 tests SEK1227
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description The IL-28RA, also known as IFNLR1, CRF-2-12, and LICR2, is a 57kD single-pass type I membrane glycoprotein containing one fibronectin III domain. Widely expressed in many tissue types, IL-28RA and IL-10RB dimerize to form the class II cytokine receptor for IL-28A (IFNλ2), IL-28B (IFNλ1) and IL-29 (IFNλ3), also known as the type III interferons. Like type I interferons, the type III interferons have been shown to activate the Jak-STAT and MAPK signalling pathways and exhibit antiviral activity. Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References
  1. Dumoutier L, et al.. 2004. J. Bio. Chem. 279:32269
Product Citations
  1. Tsai M, et al. 2022. J Biol Chem. :102698. PubMed
  2. Katakam S, et al. 2022. Life Sci Alliance. 5:. PubMed
  3. Mallampalli RK, et al. 2021. Front Immunol. 12:735576. PubMed
  4. Ghosh S, et al. 2019. Commun Biol. 0.325. PubMed
  5. Wang SQ, et al. 2021. J Viral Hepat. 28:795. PubMed
  6. Tsai M, et al. 2022. J Biol Chem. :102698. PubMed
  7. Katakam S, et al. 2022. Life Sci Alliance. 5:. PubMed
  8. Mallampalli RK, et al. 2021. Front Immunol. 12:735576. PubMed
  9. Ghosh S, et al. 2019. Commun Biol. 0.325. PubMed
  10. Wang SQ, et al. 2021. J Viral Hepat. 28:795. PubMed
RRID
AB_2125219 (BioLegend Cat. No. 337804)
AB_2125220 (BioLegend Cat. No. 337803)

Antigen Details

Structure
Single-pass type I membrane glycoprotein, one fibronectin III domain, Class II cytokine receptor, 57kD
Distribution
Broad tissue distribution at low level
Interaction
Coreceptor with IL-10RB
Ligand/Receptor
IL-28A (IFNλ2), IL-28B (IFNλ1) and IL-29 (IFNλ3)
Biology Area
Immunology
Molecular Family
Cytokine/Chemokine Receptors
Antigen References
1. Renauld et al. J. Nature reviews Imm. 2003 3:667.
2. Sheppard P et al. Nature Imm. 2003 4:63.
3. Zhou Z et al. J. Virol. 2007 81:7749.
Gene ID
163702 View all products for this Gene ID
UniProt
View information about IL-28RA on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11-30-2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Pricing & Availability
Clone
MHLICR2a (See other available formats)
Regulatory Status
RUO
Other Names
IFNLR1, CRF-2-12, LICR2
Isotype
Mouse IgG2a, κ
Ave. Rating
Submit a Review
Product Citations
publications
MHLICR2a_PE_111708.jpg
Human IL-28RA transfected BW5178 cells stained with MHLICR2a PE.
  • MHLICR2a_PE_111708.jpg
    Human IL-28RA transfected BW5178 cells stained with MHLICR2a PE.
See PE spectral data
Cat # Size Price Quantity Check Availability Save
337804 100 tests SEK2663
Check Availability


Need larger quantities of this item?
Request Bulk Quote
337803 25 tests SEK1227
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description The IL-28RA, also known as IFNLR1, CRF-2-12, and LICR2, is a 57kD single-pass type I membrane glycoprotein containing one fibronectin III domain. Widely expressed in many tissue types, IL-28RA and IL-10RB dimerize to form the class II cytokine receptor for IL-28A (IFNλ2), IL-28B (IFNλ1) and IL-29 (IFNλ3), also known as the type III interferons. Like type I interferons, the type III interferons have been shown to activate the Jak-STAT and MAPK signalling pathways and exhibit antiviral activity. Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References
  1. Dumoutier L, et al.. 2004. J. Bio. Chem. 279:32269
Product Citations
  1. Tsai M, et al. 2022. J Biol Chem. :102698. PubMed
  2. Katakam S, et al. 2022. Life Sci Alliance. 5:. PubMed
  3. Mallampalli RK, et al. 2021. Front Immunol. 12:735576. PubMed
  4. Ghosh S, et al. 2019. Commun Biol. 0.325. PubMed
  5. Wang SQ, et al. 2021. J Viral Hepat. 28:795. PubMed
  6. Tsai M, et al. 2022. J Biol Chem. :102698. PubMed
  7. Katakam S, et al. 2022. Life Sci Alliance. 5:. PubMed
  8. Mallampalli RK, et al. 2021. Front Immunol. 12:735576. PubMed
  9. Ghosh S, et al. 2019. Commun Biol. 0.325. PubMed
  10. Wang SQ, et al. 2021. J Viral Hepat. 28:795. PubMed
RRID
AB_2125219 (BioLegend Cat. No. 337804)
AB_2125220 (BioLegend Cat. No. 337803)

Antigen Details

Structure
Single-pass type I membrane glycoprotein, one fibronectin III domain, Class II cytokine receptor, 57kD
Distribution
Broad tissue distribution at low level
Interaction
Coreceptor with IL-10RB
Ligand/Receptor
IL-28A (IFNλ2), IL-28B (IFNλ1) and IL-29 (IFNλ3)
Biology Area
Immunology
Molecular Family
Cytokine/Chemokine Receptors
Antigen References
1. Renauld et al. J. Nature reviews Imm. 2003 3:667.
2. Sheppard P et al. Nature Imm. 2003 4:63.
3. Zhou Z et al. J. Virol. 2007 81:7749.
Gene ID
163702 View all products for this Gene ID
UniProt
View information about IL-28RA on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11-30-2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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