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APC/Cyanine7 anti-mouse CD3 Antibody APC/Cyanine7 anti-mouse CD3 Antibody

Pricing & Availability
Clone
17A2 (See other available formats)
Regulatory Status
RUO
Other Names
T cell antigen receptor complex, T3
Isotype
Rat IgG2b, κ
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Product Citations
publications
17A2_APCCyanine7_CD3_Antibody_031919_updated.png
C57BL/6 splenocytes were stained with CD45R/B220 FITC and CD3 (clone 17A2) APC/Cyanine7 (left) or Rat IgG2b, κ APC/Cyanine7 isotype control (right).
  • 17A2_APCCyanine7_CD3_Antibody_031919_updated.png
    C57BL/6 splenocytes were stained with CD45R/B220 FITC and CD3 (clone 17A2) APC/Cyanine7 (left) or Rat IgG2b, κ APC/Cyanine7 isotype control (right).
Compare all formats See APC/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
100221 25 µg DKK624
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100222 100 µg DKK1438
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Description

CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
γδTCR-positive T-T hybridoma D1
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is =0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported application (for relevant formats) include: spatial biology (IBEX)1,2.

Application References
  1. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  2. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Wu Y, et al. 2021. Immunity. 54:2595. PubMed
  2. Martin-Martin I, et al. 2022. Cell Rep. 39:110648. PubMed
  3. Zhou H, et al. 2022. EMBO Rep. 23:e53791. PubMed
  4. Backlund C, et al. 2022. Proc Natl Acad Sci U S A. 119:e2204078119. PubMed
  5. Lin G, et al. 2022. Int J Immunopathol Pharmacol. 36:3946320221117933. PubMed
  6. Lee SH, et al. 2023. Nutrients. 15: . PubMed
  7. Zhang B, et al. 2023. Signal Transduct Target Ther. 8:28. PubMed
  8. Meng S, et al. 2023. Stem Cell Investig. 10:2. PubMed
  9. Zhao M, et al. 2023. J Nanobiotechnology. 21:50. PubMed
  10. Abu Hejleh AP, et al. 2023. Int J Tryptophan Res. 16:11786469231153111. PubMed
  11. Ma Y, et al. 2022. Am J Physiol Heart Circ Physiol. 322:H622. PubMed
  12. Mise Y, et al. 2022. Carcinogenesis. 43:647. PubMed
  13. Tao X, et al. 2022. J Exp Med. 219:. PubMed
  14. Chen R, et al. 2022. J Mol Cell Biol. 14:. PubMed
  15. Jeon Y, et al. 2022. Cancers (Basel). 14:. PubMed
  16. Zhao Q, et al. 2023. Signal Transduct Target Ther. 8:40. PubMed
  17. Swan SL, et al. 2023. Front Immunol. 14:1085547. PubMed
  18. Spitzer D, et al. 2023. Nat Protoc. 18:1510. PubMed
  19. Wang YC, et al. 2023. J Exp Med. 220:. PubMed
  20. Li G, et al. 2023. Cell Death Dis. 14:185. PubMed
  21. Cheng MI, et al. 2023. Nat Immunol. 24:780. PubMed
  22. Do-Thi VA, et al. 2023. Cancer Res Commun. 3:80. PubMed
  23. Pelletier A, et al. 2023. EMBO Rep. 24:e56156. PubMed
  24. Tong L, et al. 2023. Sci Adv. 9:eade5041. PubMed
  25. Yazicioglu YF, et al. 2023. Nat Immunol. 24:991. PubMed
  26. Zhang J, et al. 2023. Theranostics. 13:2226. PubMed
  27. Wang Y, et al. 2023. iScience. 26:106630. PubMed
  28. van Os BW, et al. 2023. Front Cardiovasc Med. 10:1171764. PubMed
  29. Mackel JJ, et al. 2022. Front Cell Infect Microbiol. 12:974175. PubMed
  30. Chung Y, et al. 2014. J Vis Exp. 89: 51660. PubMed
  31. Sun L, et al. 2021. Cancer Cell. 39:1361. PubMed
  32. Ferrere G, et al. 2021. JCI Insight. 6:. PubMed
  33. Israelow B, et al. 2020. bioRxiv. . PubMed
  34. Marco Barros R, et al. 2016. Cell. 167: 203-218. PubMed
  35. Shimizu K, et al. 2020. Molecular Cell. 77(5):937-950.e6.. PubMed
  36. Viny AD, et al. 2019. Cell Stem Cell. 25:682. PubMed
  37. Alissafi T, et al. 2018. J Clin Invest. 128:3840. PubMed
  38. Chen S, et al. 2022. Cancer Discov. :. PubMed
  39. Coleby R, et al. 2021. Clin Exp Rheumatol. :39. PubMed
  40. Durgeau A, et al. 2018. Nat Commun. 9:5097. PubMed
  41. Silver AC, et al. 2018. Heliyon. 4:e00579. PubMed
  42. Marques RM, et al. 2021. Cell Death Differ. 28:3140. PubMed
  43. Turner JA, et al. 2020. Immunity. 53:1202. PubMed
  44. Diao L, et al. 2022. iScience. 25:105511. PubMed
  45. Tirado-Gonzalez I, et al. 2021. Cancer Discov. 11:2924. PubMed
  46. Herman JD, et al. 2021. Nat Commun. 12:6853. PubMed
  47. Tilstam PV, et al. 2021. J Clin Invest. 131:. PubMed
  48. Ma C, et al. 2021. Signal Transduct Target Ther. 6:353. PubMed
  49. Leimkühler NB, et al. 2020. Cell Stem Cell. 28:637. PubMed
  50. Zheng H, et al. 2021. Frontiers in Cell and Developmental Biology. 9:641527. PubMed
  51. Zhou Y, et al. 2016. Acta Pharmacol Sin. 10.1038/aps.2016.102. PubMed
  52. Haertel E, et al. 2018. Eur J Immunol. 48:1001. PubMed
  53. Choi H et al. 2019. Cell Rep. 27(3):806-819 . PubMed
  54. Tordesillas L, et al. 2018. Nat Commun. 9:5238. PubMed
  55. Chung H, et al. 2021. Immune Netw. 21:e28. PubMed
  56. Rafiq S, et al. 2018. Nat Biotechnol. 36:847. PubMed
  57. Mathews J, et al. 2014. PLoS One. 9:97707. PubMed
  58. Shi L, et al. 2021. Immunity. . PubMed
  59. Inoue D, et al. 2021. Nat Genet. 53:707. PubMed
  60. Super M, et al. 2021. Nat Biomed Eng. Online ahead of print. PubMed
  61. Wang Z, et al. 2020. Autophagy. 1:. PubMed
  62. Spees A, et al. 2014. Infect Immun . 82:1692. PubMed
  63. Yoshimi A, et al. 2019. Nature. 574:273. PubMed
  64. Zhao F, et al. 2022. Front Immunol. 13:873720. PubMed
  65. Kunimoto H, et al. 2018. Cancer Cell. 33:44. PubMed
  66. Wei JL, et al. 2021. J Immunother Cancer. 9: . PubMed
  67. Han JP, et al. 2022. Sci Adv. 8:eabj6901. PubMed
  68. Katsinas N, et al. 2022. J Clin Med. 11:. PubMed
  69. Xue L, et al. 2021. BMC Cancer. 21:1134. PubMed
  70. Zhang B, et al. 2021. Nat Biomed Eng. 5:1288. PubMed
  71. Pandey V, et al. 2021. eLife. 0.416666666666667. PubMed
  72. Kleppe M et al. 2018. Cancer cell. 33(1):29-43 . PubMed
  73. Grune J, et al. 2022. Nat Cardiovasc Res. 1:649. PubMed
  74. Adane B, et al. 2019. Cell Rep. 27:238. PubMed
  75. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  76. Schadt L, et al. 2020. Cell Reports. 29(5):1236-1248.e7.. PubMed
  77. Socodato R, et al. 2020. Sci Signal. 13: . PubMed
  78. Liu X, et al. 2022. Nat Cancer. :. PubMed
  79. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  80. Habib S, et al. 2018. Infect Immun. 86:e00019. PubMed
  81. Rohner L, et al. 2020. Sci Rep. 0.570833333. PubMed
  82. Alameh MG, et al. 2021. Immunity. 54:2877. PubMed
  83. Lang V, et al. 2021. Elife. 10:. PubMed
  84. Li X, et al. 2020. Nat Commun. 4.877777778. PubMed
  85. Voss M, et al. 2015. Am J Physiol Lung Cell Mol Physiol. 309: L188 - L195. PubMed
  86. Li J, et al. 2022. Nat Commun. 13:4032. PubMed
  87. Zhu W, et al. 2019. FASEB J. 33:5208. PubMed
  88. Jandke A, et al. 2020. Nat Commun. 3.075694444. PubMed
  89. Fischer FA, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  90. Robles-Oteiza C, et al. 2021. Dis Model Mech. 14:. PubMed
  91. Zhang S, et al. 2022. Nat Commun. 13:4744. PubMed
  92. Kwok T, et al. 2022. Front Aging. 3:838943. PubMed
  93. Miyauchi E, et al. 2020. Nature. 585:102. PubMed
  94. Revathikumar P, et al. 2018. PLoS One. 13:e0193210. PubMed
  95. Do-Thi VA, et al. 2021. Cancers (Basel). 13:. PubMed
  96. Teater M, et al. 2018. Nat Commun. 9:222. PubMed
  97. Draijer C, et al. 2018. Sci Rep. 8:5105. PubMed
  98. Yin S et al. 2019. Cancer cell. 35(2):283-296 . PubMed
  99. Sanchez HN, et al. 2020. Nat Commun. 0.5. PubMed
  100. Bellomo A, et al. 2020. Immunity. 53(1):127-142.e7. PubMed
  101. Dhar P, et al. 2021. Commun Biol. 4:905. PubMed
  102. Kim MY, et al. 2022. Nat Commun. 13:3296. PubMed
  103. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  104. Bagati A, et al. 2020. Cancer Cell. 39(1):54-67.e9. PubMed
  105. Israelow B, et al. 2020. J Exp Med. 217:00:00. PubMed
  106. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  107. Dokoshi T, et al. 2020. Cell Rep. 30:61. PubMed
  108. Jie Z, et al. 2014. J Immunol. 192:3289. PubMed
  109. Szodoray P, et al. 2021. Cell Reports. 36(6):109525. PubMed
  110. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  111. Rouse MD, et al. 2020. Front Microbiol. 11:414. PubMed
  112. Katzmarski N, et al. 2021. Nat Immunol. 22:1382. PubMed
  113. Li C, et al. 2021. Chem Biol Drug Des. 97:1151. PubMed
  114. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  115. Sharma R, et al. 2021. J Neuroinflammation. 72:18. PubMed
  116. Siolas D, et al. 2021. Cell Reports. 36:109578. PubMed
  117. Hildreth AD, et al. 2020. STAR Protoc. 1:100113. PubMed
  118. Wen J, et al. 2015. J Pharmacol Sci. 128: 116-124. PubMed
  119. Luo H, et al. 2019. Cell Rep. 26:945. PubMed
  120. Rodrigues KA, et al. 2021. Sci Adv. 7:eabj6538. PubMed
  121. Kojima T, et al. 2016. Sci Rep. 6:36457. PubMed
  122. Wang K, et al. 2021. Nat Commun. 12:4558. PubMed
  123. Nakazawa S, et al. 2020. Sci Rep. 10:14559. PubMed
  124. Wu Y, et al. 2021. Immunity. 54:2595. PubMed
  125. Martin-Martin I, et al. 2022. Cell Rep. 39:110648. PubMed
  126. Zhou H, et al. 2022. EMBO Rep. 23:e53791. PubMed
  127. Backlund C, et al. 2022. Proc Natl Acad Sci U S A. 119:e2204078119. PubMed
  128. Lin G, et al. 2022. Int J Immunopathol Pharmacol. 36:3946320221117933. PubMed
  129. Lee SH, et al. 2023. Nutrients. 15: . PubMed
  130. Zhang B, et al. 2023. Signal Transduct Target Ther. 8:28. PubMed
  131. Meng S, et al. 2023. Stem Cell Investig. 10:2. PubMed
  132. Zhao M, et al. 2023. J Nanobiotechnology. 21:50. PubMed
  133. Abu Hejleh AP, et al. 2023. Int J Tryptophan Res. 16:11786469231153111. PubMed
  134. Ma Y, et al. 2022. Am J Physiol Heart Circ Physiol. 322:H622. PubMed
  135. Mise Y, et al. 2022. Carcinogenesis. 43:647. PubMed
  136. Tao X, et al. 2022. J Exp Med. 219:. PubMed
  137. Chen R, et al. 2022. J Mol Cell Biol. 14:. PubMed
  138. Jeon Y, et al. 2022. Cancers (Basel). 14:. PubMed
  139. Zhao Q, et al. 2023. Signal Transduct Target Ther. 8:40. PubMed
  140. Swan SL, et al. 2023. Front Immunol. 14:1085547. PubMed
  141. Spitzer D, et al. 2023. Nat Protoc. 18:1510. PubMed
  142. Wang YC, et al. 2023. J Exp Med. 220:. PubMed
  143. Li G, et al. 2023. Cell Death Dis. 14:185. PubMed
  144. Cheng MI, et al. 2023. Nat Immunol. 24:780. PubMed
  145. Do-Thi VA, et al. 2023. Cancer Res Commun. 3:80. PubMed
  146. Pelletier A, et al. 2023. EMBO Rep. 24:e56156. PubMed
  147. Tong L, et al. 2023. Sci Adv. 9:eade5041. PubMed
  148. Yazicioglu YF, et al. 2023. Nat Immunol. 24:991. PubMed
  149. Zhang J, et al. 2023. Theranostics. 13:2226. PubMed
  150. Wang Y, et al. 2023. iScience. 26:106630. PubMed
  151. van Os BW, et al. 2023. Front Cardiovasc Med. 10:1171764. PubMed
  152. Mackel JJ, et al. 2022. Front Cell Infect Microbiol. 12:974175. PubMed
  153. Chung Y, et al. 2014. J Vis Exp. 89: 51660. PubMed
  154. Sun L, et al. 2021. Cancer Cell. 39:1361. PubMed
  155. Ferrere G, et al. 2021. JCI Insight. 6:. PubMed
  156. Israelow B, et al. 2020. bioRxiv. . PubMed
  157. Marco Barros R, et al. 2016. Cell. 167: 203-218. PubMed
  158. Shimizu K, et al. 2020. Molecular Cell. 77(5):937-950.e6.. PubMed
  159. Viny AD, et al. 2019. Cell Stem Cell. 25:682. PubMed
  160. Alissafi T, et al. 2018. J Clin Invest. 128:3840. PubMed
  161. Chen S, et al. 2022. Cancer Discov. :. PubMed
  162. Coleby R, et al. 2021. Clin Exp Rheumatol. :39. PubMed
  163. Durgeau A, et al. 2018. Nat Commun. 9:5097. PubMed
  164. Silver AC, et al. 2018. Heliyon. 4:e00579. PubMed
  165. Marques RM, et al. 2021. Cell Death Differ. 28:3140. PubMed
  166. Turner JA, et al. 2020. Immunity. 53:1202. PubMed
  167. Diao L, et al. 2022. iScience. 25:105511. PubMed
  168. Tirado-Gonzalez I, et al. 2021. Cancer Discov. 11:2924. PubMed
  169. Herman JD, et al. 2021. Nat Commun. 12:6853. PubMed
  170. Tilstam PV, et al. 2021. J Clin Invest. 131:. PubMed
  171. Ma C, et al. 2021. Signal Transduct Target Ther. 6:353. PubMed
  172. Leimkühler NB, et al. 2020. Cell Stem Cell. 28:637. PubMed
  173. Zheng H, et al. 2021. Frontiers in Cell and Developmental Biology. 9:641527. PubMed
  174. Zhou Y, et al. 2016. Acta Pharmacol Sin. 10.1038/aps.2016.102. PubMed
  175. Haertel E, et al. 2018. Eur J Immunol. 48:1001. PubMed
  176. Choi H et al. 2019. Cell Rep. 27(3):806-819 . PubMed
  177. Tordesillas L, et al. 2018. Nat Commun. 9:5238. PubMed
  178. Chung H, et al. 2021. Immune Netw. 21:e28. PubMed
  179. Rafiq S, et al. 2018. Nat Biotechnol. 36:847. PubMed
  180. Mathews J, et al. 2014. PLoS One. 9:97707. PubMed
  181. Shi L, et al. 2021. Immunity. . PubMed
  182. Inoue D, et al. 2021. Nat Genet. 53:707. PubMed
  183. Super M, et al. 2021. Nat Biomed Eng. Online ahead of print. PubMed
  184. Wang Z, et al. 2020. Autophagy. 1:. PubMed
  185. Spees A, et al. 2014. Infect Immun . 82:1692. PubMed
  186. Yoshimi A, et al. 2019. Nature. 574:273. PubMed
  187. Zhao F, et al. 2022. Front Immunol. 13:873720. PubMed
  188. Kunimoto H, et al. 2018. Cancer Cell. 33:44. PubMed
  189. Wei JL, et al. 2021. J Immunother Cancer. 9: . PubMed
  190. Han JP, et al. 2022. Sci Adv. 8:eabj6901. PubMed
  191. Katsinas N, et al. 2022. J Clin Med. 11:. PubMed
  192. Xue L, et al. 2021. BMC Cancer. 21:1134. PubMed
  193. Zhang B, et al. 2021. Nat Biomed Eng. 5:1288. PubMed
  194. Pandey V, et al. 2021. eLife. 0.416666666666667. PubMed
  195. Kleppe M et al. 2018. Cancer cell. 33(1):29-43 . PubMed
  196. Grune J, et al. 2022. Nat Cardiovasc Res. 1:649. PubMed
  197. Adane B, et al. 2019. Cell Rep. 27:238. PubMed
  198. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  199. Schadt L, et al. 2020. Cell Reports. 29(5):1236-1248.e7.. PubMed
  200. Socodato R, et al. 2020. Sci Signal. 13: . PubMed
  201. Liu X, et al. 2022. Nat Cancer. :. PubMed
  202. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  203. Habib S, et al. 2018. Infect Immun. 86:e00019. PubMed
  204. Rohner L, et al. 2020. Sci Rep. 0.570833333. PubMed
  205. Alameh MG, et al. 2021. Immunity. 54:2877. PubMed
  206. Lang V, et al. 2021. Elife. 10:. PubMed
  207. Li X, et al. 2020. Nat Commun. 4.877777778. PubMed
  208. Voss M, et al. 2015. Am J Physiol Lung Cell Mol Physiol. 309: L188 - L195. PubMed
  209. Li J, et al. 2022. Nat Commun. 13:4032. PubMed
  210. Zhu W, et al. 2019. FASEB J. 33:5208. PubMed
  211. Jandke A, et al. 2020. Nat Commun. 3.075694444. PubMed
  212. Fischer FA, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  213. Robles-Oteiza C, et al. 2021. Dis Model Mech. 14:. PubMed
  214. Zhang S, et al. 2022. Nat Commun. 13:4744. PubMed
  215. Kwok T, et al. 2022. Front Aging. 3:838943. PubMed
  216. Miyauchi E, et al. 2020. Nature. 585:102. PubMed
  217. Revathikumar P, et al. 2018. PLoS One. 13:e0193210. PubMed
  218. Do-Thi VA, et al. 2021. Cancers (Basel). 13:. PubMed
  219. Teater M, et al. 2018. Nat Commun. 9:222. PubMed
  220. Draijer C, et al. 2018. Sci Rep. 8:5105. PubMed
  221. Yin S et al. 2019. Cancer cell. 35(2):283-296 . PubMed
  222. Sanchez HN, et al. 2020. Nat Commun. 0.5. PubMed
  223. Bellomo A, et al. 2020. Immunity. 53(1):127-142.e7. PubMed
  224. Dhar P, et al. 2021. Commun Biol. 4:905. PubMed
  225. Kim MY, et al. 2022. Nat Commun. 13:3296. PubMed
  226. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  227. Bagati A, et al. 2020. Cancer Cell. 39(1):54-67.e9. PubMed
  228. Israelow B, et al. 2020. J Exp Med. 217:00:00. PubMed
  229. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  230. Dokoshi T, et al. 2020. Cell Rep. 30:61. PubMed
  231. Jie Z, et al. 2014. J Immunol. 192:3289. PubMed
  232. Szodoray P, et al. 2021. Cell Reports. 36(6):109525. PubMed
  233. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  234. Rouse MD, et al. 2020. Front Microbiol. 11:414. PubMed
  235. Katzmarski N, et al. 2021. Nat Immunol. 22:1382. PubMed
  236. Li C, et al. 2021. Chem Biol Drug Des. 97:1151. PubMed
  237. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  238. Sharma R, et al. 2021. J Neuroinflammation. 72:18. PubMed
  239. Siolas D, et al. 2021. Cell Reports. 36:109578. PubMed
  240. Hildreth AD, et al. 2020. STAR Protoc. 1:100113. PubMed
  241. Wen J, et al. 2015. J Pharmacol Sci. 128: 116-124. PubMed
  242. Luo H, et al. 2019. Cell Rep. 26:945. PubMed
  243. Rodrigues KA, et al. 2021. Sci Adv. 7:eabj6538. PubMed
  244. Kojima T, et al. 2016. Sci Rep. 6:36457. PubMed
  245. Wang K, et al. 2021. Nat Commun. 12:4558. PubMed
  246. Nakazawa S, et al. 2020. Sci Rep. 10:14559. PubMed
RRID
AB_2057374 (BioLegend Cat. No. 100221)
AB_2242784 (BioLegend Cat. No. 100222)

Antigen Details

Structure
Ig superfamily, CD3/TCR, 20 kD
Distribution

Thymocytes (differentiation dependent), mature T cells, NK-T cells

Function
Antigen recognition, TCR signal transduction, T cell activation
Ligand/Receptor
Peptide antigen/MHC-complex
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Davis MM. 1990. Annu. Rev. Biochem. 59:475.
3. Weiss A, et al. 1994. Cell 76:263.

Gene ID
12502 View all products for this Gene ID
UniProt
View information about CD3 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD3 Reagents Request Custom Conjugation
Description Clone Applications
Brilliant Violet 711™ anti-mouse CD3 17A2 FC
Biotin anti-mouse CD3 17A2 FC,IHC-F
PE/Dazzle™ 594 anti-mouse CD3 17A2 FC
APC/Fire™ 750 anti-mouse CD3 17A2 FC
Brilliant Violet 750™ anti-mouse CD3 17A2 FC
TotalSeq™-A0182 anti-mouse CD3 17A2 PG
TotalSeq™-B0182 anti-mouse CD3 17A2 PG
Spark Blue™ 550 anti-mouse CD3 17A2 FC
Spark NIR™ 685 anti-mouse CD3 17A2 FC
TotalSeq™-C0182 anti-mouse CD3 17A2 PG
APC/Fire™ 810 anti-mouse CD3 17A2 FC
PE/Fire™ 640 anti-mouse CD3 17A2 FC
Spark YG™ 570 anti-mouse CD3 17A2 IHC-F
PE/Fire™ 700 anti-mouse CD3 17A2 FC
Test 17A2 5 17A2
FITC anti-mouse CD3 17A2 FC
PE anti-mouse CD3 17A2 FC
Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Alexa Fluor® 647 anti-mouse CD3 17A2 FC,IHC-F,3D IHC,SB
Alexa Fluor® 488 anti-mouse CD3 17A2 FC,IHC-F,3D IHC
Pacific Blue™ anti-mouse CD3 17A2 FC
Alexa Fluor® 700 anti-mouse CD3 17A2 FC
PerCP/Cyanine5.5 anti-mouse CD3 17A2 FC
PE/Cyanine7 anti-mouse CD3 17A2 FC
APC/Cyanine7 anti-mouse CD3 17A2 FC
Brilliant Violet 421™ anti-mouse CD3 17A2 FC,ICC
Brilliant Violet 570™ anti-mouse CD3 17A2 FC
Brilliant Violet 650™ anti-mouse CD3 17A2 FC
Brilliant Violet 785™ anti-mouse CD3 17A2 FC
Brilliant Violet 510™ anti-mouse CD3 17A2 FC
APC anti-mouse CD3 17A2 FC
Ultra-LEAF™ Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Brilliant Violet 605™ anti-mouse CD3 17A2 FC
Alexa Fluor® 594 anti-mouse CD3 17A2 IHC-F,FC,3D IHC,SB
PE/Cyanine5 anti-mouse CD3 17A2 FC
Spark Blue™ 574 anti-mouse CD3 Antibody 17A2 FC
Spark Violet™ 423 anti-mouse CD3 17A2 FC
PE/Fire™ 810 anti-mouse CD3 17A2 FC
Spark Red™ 718 anti-mouse CD3 17A2 FC
Spark UV™ 387 anti-mouse CD3 17A2 FC
PerCP/Fire™ 780 anti-mouse CD3 Antibody 17A2 FC
PerCP anti-mouse CD3 Antibody 17A2 FC
Spark YG™ 581 anti-mouse CD3 (Flexi-Fluor™) 17A2 FC
Spark YG™ 593 anti-mouse CD3 (Flexi-Fluor™) Antibody 17A2 FC
Spark PLUS B488™ anti-mouse CD3 17A2 FC
Go To Top Version: 3    Revision Date: 03/19/2019

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Pricing & Availability
Clone
17A2 (See other available formats)
Regulatory Status
RUO
Other Names
T cell antigen receptor complex, T3
Isotype
Rat IgG2b, κ
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Product Citations
publications
17A2_APCCyanine7_CD3_Antibody_031919_updated.png
C57BL/6 splenocytes were stained with CD45R/B220 FITC and CD3 (clone 17A2) APC/Cyanine7 (left) or Rat IgG2b, κ APC/Cyanine7 isotype control (right).
  • 17A2_APCCyanine7_CD3_Antibody_031919_updated.png
    C57BL/6 splenocytes were stained with CD45R/B220 FITC and CD3 (clone 17A2) APC/Cyanine7 (left) or Rat IgG2b, κ APC/Cyanine7 isotype control (right).
Compare all formats See APC/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
100221 25 µg DKK624
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100222 100 µg DKK1438
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Description

CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
γδTCR-positive T-T hybridoma D1
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is =0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported application (for relevant formats) include: spatial biology (IBEX)1,2.

Application References
  1. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  2. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Wu Y, et al. 2021. Immunity. 54:2595. PubMed
  2. Martin-Martin I, et al. 2022. Cell Rep. 39:110648. PubMed
  3. Zhou H, et al. 2022. EMBO Rep. 23:e53791. PubMed
  4. Backlund C, et al. 2022. Proc Natl Acad Sci U S A. 119:e2204078119. PubMed
  5. Lin G, et al. 2022. Int J Immunopathol Pharmacol. 36:3946320221117933. PubMed
  6. Lee SH, et al. 2023. Nutrients. 15: . PubMed
  7. Zhang B, et al. 2023. Signal Transduct Target Ther. 8:28. PubMed
  8. Meng S, et al. 2023. Stem Cell Investig. 10:2. PubMed
  9. Zhao M, et al. 2023. J Nanobiotechnology. 21:50. PubMed
  10. Abu Hejleh AP, et al. 2023. Int J Tryptophan Res. 16:11786469231153111. PubMed
  11. Ma Y, et al. 2022. Am J Physiol Heart Circ Physiol. 322:H622. PubMed
  12. Mise Y, et al. 2022. Carcinogenesis. 43:647. PubMed
  13. Tao X, et al. 2022. J Exp Med. 219:. PubMed
  14. Chen R, et al. 2022. J Mol Cell Biol. 14:. PubMed
  15. Jeon Y, et al. 2022. Cancers (Basel). 14:. PubMed
  16. Zhao Q, et al. 2023. Signal Transduct Target Ther. 8:40. PubMed
  17. Swan SL, et al. 2023. Front Immunol. 14:1085547. PubMed
  18. Spitzer D, et al. 2023. Nat Protoc. 18:1510. PubMed
  19. Wang YC, et al. 2023. J Exp Med. 220:. PubMed
  20. Li G, et al. 2023. Cell Death Dis. 14:185. PubMed
  21. Cheng MI, et al. 2023. Nat Immunol. 24:780. PubMed
  22. Do-Thi VA, et al. 2023. Cancer Res Commun. 3:80. PubMed
  23. Pelletier A, et al. 2023. EMBO Rep. 24:e56156. PubMed
  24. Tong L, et al. 2023. Sci Adv. 9:eade5041. PubMed
  25. Yazicioglu YF, et al. 2023. Nat Immunol. 24:991. PubMed
  26. Zhang J, et al. 2023. Theranostics. 13:2226. PubMed
  27. Wang Y, et al. 2023. iScience. 26:106630. PubMed
  28. van Os BW, et al. 2023. Front Cardiovasc Med. 10:1171764. PubMed
  29. Mackel JJ, et al. 2022. Front Cell Infect Microbiol. 12:974175. PubMed
  30. Chung Y, et al. 2014. J Vis Exp. 89: 51660. PubMed
  31. Sun L, et al. 2021. Cancer Cell. 39:1361. PubMed
  32. Ferrere G, et al. 2021. JCI Insight. 6:. PubMed
  33. Israelow B, et al. 2020. bioRxiv. . PubMed
  34. Marco Barros R, et al. 2016. Cell. 167: 203-218. PubMed
  35. Shimizu K, et al. 2020. Molecular Cell. 77(5):937-950.e6.. PubMed
  36. Viny AD, et al. 2019. Cell Stem Cell. 25:682. PubMed
  37. Alissafi T, et al. 2018. J Clin Invest. 128:3840. PubMed
  38. Chen S, et al. 2022. Cancer Discov. :. PubMed
  39. Coleby R, et al. 2021. Clin Exp Rheumatol. :39. PubMed
  40. Durgeau A, et al. 2018. Nat Commun. 9:5097. PubMed
  41. Silver AC, et al. 2018. Heliyon. 4:e00579. PubMed
  42. Marques RM, et al. 2021. Cell Death Differ. 28:3140. PubMed
  43. Turner JA, et al. 2020. Immunity. 53:1202. PubMed
  44. Diao L, et al. 2022. iScience. 25:105511. PubMed
  45. Tirado-Gonzalez I, et al. 2021. Cancer Discov. 11:2924. PubMed
  46. Herman JD, et al. 2021. Nat Commun. 12:6853. PubMed
  47. Tilstam PV, et al. 2021. J Clin Invest. 131:. PubMed
  48. Ma C, et al. 2021. Signal Transduct Target Ther. 6:353. PubMed
  49. Leimkühler NB, et al. 2020. Cell Stem Cell. 28:637. PubMed
  50. Zheng H, et al. 2021. Frontiers in Cell and Developmental Biology. 9:641527. PubMed
  51. Zhou Y, et al. 2016. Acta Pharmacol Sin. 10.1038/aps.2016.102. PubMed
  52. Haertel E, et al. 2018. Eur J Immunol. 48:1001. PubMed
  53. Choi H et al. 2019. Cell Rep. 27(3):806-819 . PubMed
  54. Tordesillas L, et al. 2018. Nat Commun. 9:5238. PubMed
  55. Chung H, et al. 2021. Immune Netw. 21:e28. PubMed
  56. Rafiq S, et al. 2018. Nat Biotechnol. 36:847. PubMed
  57. Mathews J, et al. 2014. PLoS One. 9:97707. PubMed
  58. Shi L, et al. 2021. Immunity. . PubMed
  59. Inoue D, et al. 2021. Nat Genet. 53:707. PubMed
  60. Super M, et al. 2021. Nat Biomed Eng. Online ahead of print. PubMed
  61. Wang Z, et al. 2020. Autophagy. 1:. PubMed
  62. Spees A, et al. 2014. Infect Immun . 82:1692. PubMed
  63. Yoshimi A, et al. 2019. Nature. 574:273. PubMed
  64. Zhao F, et al. 2022. Front Immunol. 13:873720. PubMed
  65. Kunimoto H, et al. 2018. Cancer Cell. 33:44. PubMed
  66. Wei JL, et al. 2021. J Immunother Cancer. 9: . PubMed
  67. Han JP, et al. 2022. Sci Adv. 8:eabj6901. PubMed
  68. Katsinas N, et al. 2022. J Clin Med. 11:. PubMed
  69. Xue L, et al. 2021. BMC Cancer. 21:1134. PubMed
  70. Zhang B, et al. 2021. Nat Biomed Eng. 5:1288. PubMed
  71. Pandey V, et al. 2021. eLife. 0.416666666666667. PubMed
  72. Kleppe M et al. 2018. Cancer cell. 33(1):29-43 . PubMed
  73. Grune J, et al. 2022. Nat Cardiovasc Res. 1:649. PubMed
  74. Adane B, et al. 2019. Cell Rep. 27:238. PubMed
  75. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  76. Schadt L, et al. 2020. Cell Reports. 29(5):1236-1248.e7.. PubMed
  77. Socodato R, et al. 2020. Sci Signal. 13: . PubMed
  78. Liu X, et al. 2022. Nat Cancer. :. PubMed
  79. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  80. Habib S, et al. 2018. Infect Immun. 86:e00019. PubMed
  81. Rohner L, et al. 2020. Sci Rep. 0.570833333. PubMed
  82. Alameh MG, et al. 2021. Immunity. 54:2877. PubMed
  83. Lang V, et al. 2021. Elife. 10:. PubMed
  84. Li X, et al. 2020. Nat Commun. 4.877777778. PubMed
  85. Voss M, et al. 2015. Am J Physiol Lung Cell Mol Physiol. 309: L188 - L195. PubMed
  86. Li J, et al. 2022. Nat Commun. 13:4032. PubMed
  87. Zhu W, et al. 2019. FASEB J. 33:5208. PubMed
  88. Jandke A, et al. 2020. Nat Commun. 3.075694444. PubMed
  89. Fischer FA, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  90. Robles-Oteiza C, et al. 2021. Dis Model Mech. 14:. PubMed
  91. Zhang S, et al. 2022. Nat Commun. 13:4744. PubMed
  92. Kwok T, et al. 2022. Front Aging. 3:838943. PubMed
  93. Miyauchi E, et al. 2020. Nature. 585:102. PubMed
  94. Revathikumar P, et al. 2018. PLoS One. 13:e0193210. PubMed
  95. Do-Thi VA, et al. 2021. Cancers (Basel). 13:. PubMed
  96. Teater M, et al. 2018. Nat Commun. 9:222. PubMed
  97. Draijer C, et al. 2018. Sci Rep. 8:5105. PubMed
  98. Yin S et al. 2019. Cancer cell. 35(2):283-296 . PubMed
  99. Sanchez HN, et al. 2020. Nat Commun. 0.5. PubMed
  100. Bellomo A, et al. 2020. Immunity. 53(1):127-142.e7. PubMed
  101. Dhar P, et al. 2021. Commun Biol. 4:905. PubMed
  102. Kim MY, et al. 2022. Nat Commun. 13:3296. PubMed
  103. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  104. Bagati A, et al. 2020. Cancer Cell. 39(1):54-67.e9. PubMed
  105. Israelow B, et al. 2020. J Exp Med. 217:00:00. PubMed
  106. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  107. Dokoshi T, et al. 2020. Cell Rep. 30:61. PubMed
  108. Jie Z, et al. 2014. J Immunol. 192:3289. PubMed
  109. Szodoray P, et al. 2021. Cell Reports. 36(6):109525. PubMed
  110. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  111. Rouse MD, et al. 2020. Front Microbiol. 11:414. PubMed
  112. Katzmarski N, et al. 2021. Nat Immunol. 22:1382. PubMed
  113. Li C, et al. 2021. Chem Biol Drug Des. 97:1151. PubMed
  114. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  115. Sharma R, et al. 2021. J Neuroinflammation. 72:18. PubMed
  116. Siolas D, et al. 2021. Cell Reports. 36:109578. PubMed
  117. Hildreth AD, et al. 2020. STAR Protoc. 1:100113. PubMed
  118. Wen J, et al. 2015. J Pharmacol Sci. 128: 116-124. PubMed
  119. Luo H, et al. 2019. Cell Rep. 26:945. PubMed
  120. Rodrigues KA, et al. 2021. Sci Adv. 7:eabj6538. PubMed
  121. Kojima T, et al. 2016. Sci Rep. 6:36457. PubMed
  122. Wang K, et al. 2021. Nat Commun. 12:4558. PubMed
  123. Nakazawa S, et al. 2020. Sci Rep. 10:14559. PubMed
  124. Wu Y, et al. 2021. Immunity. 54:2595. PubMed
  125. Martin-Martin I, et al. 2022. Cell Rep. 39:110648. PubMed
  126. Zhou H, et al. 2022. EMBO Rep. 23:e53791. PubMed
  127. Backlund C, et al. 2022. Proc Natl Acad Sci U S A. 119:e2204078119. PubMed
  128. Lin G, et al. 2022. Int J Immunopathol Pharmacol. 36:3946320221117933. PubMed
  129. Lee SH, et al. 2023. Nutrients. 15: . PubMed
  130. Zhang B, et al. 2023. Signal Transduct Target Ther. 8:28. PubMed
  131. Meng S, et al. 2023. Stem Cell Investig. 10:2. PubMed
  132. Zhao M, et al. 2023. J Nanobiotechnology. 21:50. PubMed
  133. Abu Hejleh AP, et al. 2023. Int J Tryptophan Res. 16:11786469231153111. PubMed
  134. Ma Y, et al. 2022. Am J Physiol Heart Circ Physiol. 322:H622. PubMed
  135. Mise Y, et al. 2022. Carcinogenesis. 43:647. PubMed
  136. Tao X, et al. 2022. J Exp Med. 219:. PubMed
  137. Chen R, et al. 2022. J Mol Cell Biol. 14:. PubMed
  138. Jeon Y, et al. 2022. Cancers (Basel). 14:. PubMed
  139. Zhao Q, et al. 2023. Signal Transduct Target Ther. 8:40. PubMed
  140. Swan SL, et al. 2023. Front Immunol. 14:1085547. PubMed
  141. Spitzer D, et al. 2023. Nat Protoc. 18:1510. PubMed
  142. Wang YC, et al. 2023. J Exp Med. 220:. PubMed
  143. Li G, et al. 2023. Cell Death Dis. 14:185. PubMed
  144. Cheng MI, et al. 2023. Nat Immunol. 24:780. PubMed
  145. Do-Thi VA, et al. 2023. Cancer Res Commun. 3:80. PubMed
  146. Pelletier A, et al. 2023. EMBO Rep. 24:e56156. PubMed
  147. Tong L, et al. 2023. Sci Adv. 9:eade5041. PubMed
  148. Yazicioglu YF, et al. 2023. Nat Immunol. 24:991. PubMed
  149. Zhang J, et al. 2023. Theranostics. 13:2226. PubMed
  150. Wang Y, et al. 2023. iScience. 26:106630. PubMed
  151. van Os BW, et al. 2023. Front Cardiovasc Med. 10:1171764. PubMed
  152. Mackel JJ, et al. 2022. Front Cell Infect Microbiol. 12:974175. PubMed
  153. Chung Y, et al. 2014. J Vis Exp. 89: 51660. PubMed
  154. Sun L, et al. 2021. Cancer Cell. 39:1361. PubMed
  155. Ferrere G, et al. 2021. JCI Insight. 6:. PubMed
  156. Israelow B, et al. 2020. bioRxiv. . PubMed
  157. Marco Barros R, et al. 2016. Cell. 167: 203-218. PubMed
  158. Shimizu K, et al. 2020. Molecular Cell. 77(5):937-950.e6.. PubMed
  159. Viny AD, et al. 2019. Cell Stem Cell. 25:682. PubMed
  160. Alissafi T, et al. 2018. J Clin Invest. 128:3840. PubMed
  161. Chen S, et al. 2022. Cancer Discov. :. PubMed
  162. Coleby R, et al. 2021. Clin Exp Rheumatol. :39. PubMed
  163. Durgeau A, et al. 2018. Nat Commun. 9:5097. PubMed
  164. Silver AC, et al. 2018. Heliyon. 4:e00579. PubMed
  165. Marques RM, et al. 2021. Cell Death Differ. 28:3140. PubMed
  166. Turner JA, et al. 2020. Immunity. 53:1202. PubMed
  167. Diao L, et al. 2022. iScience. 25:105511. PubMed
  168. Tirado-Gonzalez I, et al. 2021. Cancer Discov. 11:2924. PubMed
  169. Herman JD, et al. 2021. Nat Commun. 12:6853. PubMed
  170. Tilstam PV, et al. 2021. J Clin Invest. 131:. PubMed
  171. Ma C, et al. 2021. Signal Transduct Target Ther. 6:353. PubMed
  172. Leimkühler NB, et al. 2020. Cell Stem Cell. 28:637. PubMed
  173. Zheng H, et al. 2021. Frontiers in Cell and Developmental Biology. 9:641527. PubMed
  174. Zhou Y, et al. 2016. Acta Pharmacol Sin. 10.1038/aps.2016.102. PubMed
  175. Haertel E, et al. 2018. Eur J Immunol. 48:1001. PubMed
  176. Choi H et al. 2019. Cell Rep. 27(3):806-819 . PubMed
  177. Tordesillas L, et al. 2018. Nat Commun. 9:5238. PubMed
  178. Chung H, et al. 2021. Immune Netw. 21:e28. PubMed
  179. Rafiq S, et al. 2018. Nat Biotechnol. 36:847. PubMed
  180. Mathews J, et al. 2014. PLoS One. 9:97707. PubMed
  181. Shi L, et al. 2021. Immunity. . PubMed
  182. Inoue D, et al. 2021. Nat Genet. 53:707. PubMed
  183. Super M, et al. 2021. Nat Biomed Eng. Online ahead of print. PubMed
  184. Wang Z, et al. 2020. Autophagy. 1:. PubMed
  185. Spees A, et al. 2014. Infect Immun . 82:1692. PubMed
  186. Yoshimi A, et al. 2019. Nature. 574:273. PubMed
  187. Zhao F, et al. 2022. Front Immunol. 13:873720. PubMed
  188. Kunimoto H, et al. 2018. Cancer Cell. 33:44. PubMed
  189. Wei JL, et al. 2021. J Immunother Cancer. 9: . PubMed
  190. Han JP, et al. 2022. Sci Adv. 8:eabj6901. PubMed
  191. Katsinas N, et al. 2022. J Clin Med. 11:. PubMed
  192. Xue L, et al. 2021. BMC Cancer. 21:1134. PubMed
  193. Zhang B, et al. 2021. Nat Biomed Eng. 5:1288. PubMed
  194. Pandey V, et al. 2021. eLife. 0.416666666666667. PubMed
  195. Kleppe M et al. 2018. Cancer cell. 33(1):29-43 . PubMed
  196. Grune J, et al. 2022. Nat Cardiovasc Res. 1:649. PubMed
  197. Adane B, et al. 2019. Cell Rep. 27:238. PubMed
  198. Rashidi M, et al. 2019. J Immunol. 203:736. PubMed
  199. Schadt L, et al. 2020. Cell Reports. 29(5):1236-1248.e7.. PubMed
  200. Socodato R, et al. 2020. Sci Signal. 13: . PubMed
  201. Liu X, et al. 2022. Nat Cancer. :. PubMed
  202. Harb H, et al. 2021. Immunity. 54(6):1186-1199.e7. PubMed
  203. Habib S, et al. 2018. Infect Immun. 86:e00019. PubMed
  204. Rohner L, et al. 2020. Sci Rep. 0.570833333. PubMed
  205. Alameh MG, et al. 2021. Immunity. 54:2877. PubMed
  206. Lang V, et al. 2021. Elife. 10:. PubMed
  207. Li X, et al. 2020. Nat Commun. 4.877777778. PubMed
  208. Voss M, et al. 2015. Am J Physiol Lung Cell Mol Physiol. 309: L188 - L195. PubMed
  209. Li J, et al. 2022. Nat Commun. 13:4032. PubMed
  210. Zhu W, et al. 2019. FASEB J. 33:5208. PubMed
  211. Jandke A, et al. 2020. Nat Commun. 3.075694444. PubMed
  212. Fischer FA, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  213. Robles-Oteiza C, et al. 2021. Dis Model Mech. 14:. PubMed
  214. Zhang S, et al. 2022. Nat Commun. 13:4744. PubMed
  215. Kwok T, et al. 2022. Front Aging. 3:838943. PubMed
  216. Miyauchi E, et al. 2020. Nature. 585:102. PubMed
  217. Revathikumar P, et al. 2018. PLoS One. 13:e0193210. PubMed
  218. Do-Thi VA, et al. 2021. Cancers (Basel). 13:. PubMed
  219. Teater M, et al. 2018. Nat Commun. 9:222. PubMed
  220. Draijer C, et al. 2018. Sci Rep. 8:5105. PubMed
  221. Yin S et al. 2019. Cancer cell. 35(2):283-296 . PubMed
  222. Sanchez HN, et al. 2020. Nat Commun. 0.5. PubMed
  223. Bellomo A, et al. 2020. Immunity. 53(1):127-142.e7. PubMed
  224. Dhar P, et al. 2021. Commun Biol. 4:905. PubMed
  225. Kim MY, et al. 2022. Nat Commun. 13:3296. PubMed
  226. Chen C, et al. 2020. Cell Rep. 2136:30. PubMed
  227. Bagati A, et al. 2020. Cancer Cell. 39(1):54-67.e9. PubMed
  228. Israelow B, et al. 2020. J Exp Med. 217:00:00. PubMed
  229. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  230. Dokoshi T, et al. 2020. Cell Rep. 30:61. PubMed
  231. Jie Z, et al. 2014. J Immunol. 192:3289. PubMed
  232. Szodoray P, et al. 2021. Cell Reports. 36(6):109525. PubMed
  233. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  234. Rouse MD, et al. 2020. Front Microbiol. 11:414. PubMed
  235. Katzmarski N, et al. 2021. Nat Immunol. 22:1382. PubMed
  236. Li C, et al. 2021. Chem Biol Drug Des. 97:1151. PubMed
  237. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  238. Sharma R, et al. 2021. J Neuroinflammation. 72:18. PubMed
  239. Siolas D, et al. 2021. Cell Reports. 36:109578. PubMed
  240. Hildreth AD, et al. 2020. STAR Protoc. 1:100113. PubMed
  241. Wen J, et al. 2015. J Pharmacol Sci. 128: 116-124. PubMed
  242. Luo H, et al. 2019. Cell Rep. 26:945. PubMed
  243. Rodrigues KA, et al. 2021. Sci Adv. 7:eabj6538. PubMed
  244. Kojima T, et al. 2016. Sci Rep. 6:36457. PubMed
  245. Wang K, et al. 2021. Nat Commun. 12:4558. PubMed
  246. Nakazawa S, et al. 2020. Sci Rep. 10:14559. PubMed
RRID
AB_2057374 (BioLegend Cat. No. 100221)
AB_2242784 (BioLegend Cat. No. 100222)

Antigen Details

Structure
Ig superfamily, CD3/TCR, 20 kD
Distribution

Thymocytes (differentiation dependent), mature T cells, NK-T cells

Function
Antigen recognition, TCR signal transduction, T cell activation
Ligand/Receptor
Peptide antigen/MHC-complex
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Davis MM. 1990. Annu. Rev. Biochem. 59:475.
3. Weiss A, et al. 1994. Cell 76:263.

Gene ID
12502 View all products for this Gene ID
UniProt
View information about CD3 on UniProt.org

Other Formats

View All CD3 Reagents Request Custom Conjugation
Description Clone Applications
Brilliant Violet 711™ anti-mouse CD3 17A2 FC
Biotin anti-mouse CD3 17A2 FC,IHC-F
PE/Dazzle™ 594 anti-mouse CD3 17A2 FC
APC/Fire™ 750 anti-mouse CD3 17A2 FC
Brilliant Violet 750™ anti-mouse CD3 17A2 FC
TotalSeq™-A0182 anti-mouse CD3 17A2 PG
TotalSeq™-B0182 anti-mouse CD3 17A2 PG
Spark Blue™ 550 anti-mouse CD3 17A2 FC
Spark NIR™ 685 anti-mouse CD3 17A2 FC
TotalSeq™-C0182 anti-mouse CD3 17A2 PG
APC/Fire™ 810 anti-mouse CD3 17A2 FC
PE/Fire™ 640 anti-mouse CD3 17A2 FC
Spark YG™ 570 anti-mouse CD3 17A2 IHC-F
PE/Fire™ 700 anti-mouse CD3 17A2 FC
Test 17A2 5 17A2
FITC anti-mouse CD3 17A2 FC
PE anti-mouse CD3 17A2 FC
Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Alexa Fluor® 647 anti-mouse CD3 17A2 FC,IHC-F,3D IHC,SB
Alexa Fluor® 488 anti-mouse CD3 17A2 FC,IHC-F,3D IHC
Pacific Blue™ anti-mouse CD3 17A2 FC
Alexa Fluor® 700 anti-mouse CD3 17A2 FC
PerCP/Cyanine5.5 anti-mouse CD3 17A2 FC
PE/Cyanine7 anti-mouse CD3 17A2 FC
APC/Cyanine7 anti-mouse CD3 17A2 FC
Brilliant Violet 421™ anti-mouse CD3 17A2 FC,ICC
Brilliant Violet 570™ anti-mouse CD3 17A2 FC
Brilliant Violet 650™ anti-mouse CD3 17A2 FC
Brilliant Violet 785™ anti-mouse CD3 17A2 FC
Brilliant Violet 510™ anti-mouse CD3 17A2 FC
APC anti-mouse CD3 17A2 FC
Ultra-LEAF™ Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Brilliant Violet 605™ anti-mouse CD3 17A2 FC
Alexa Fluor® 594 anti-mouse CD3 17A2 IHC-F,FC,3D IHC,SB
PE/Cyanine5 anti-mouse CD3 17A2 FC
Spark Blue™ 574 anti-mouse CD3 Antibody 17A2 FC
Spark Violet™ 423 anti-mouse CD3 17A2 FC
PE/Fire™ 810 anti-mouse CD3 17A2 FC
Spark Red™ 718 anti-mouse CD3 17A2 FC
Spark UV™ 387 anti-mouse CD3 17A2 FC
PerCP/Fire™ 780 anti-mouse CD3 Antibody 17A2 FC
PerCP anti-mouse CD3 Antibody 17A2 FC
Spark YG™ 581 anti-mouse CD3 (Flexi-Fluor™) 17A2 FC
Spark YG™ 593 anti-mouse CD3 (Flexi-Fluor™) Antibody 17A2 FC
Spark PLUS B488™ anti-mouse CD3 17A2 FC
Go To Top Version: 3    Revision Date: 03/19/2019

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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