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PE/Cyanine7 anti-mouse CD3 Antibody PE/Cyanine7 anti-mouse CD3 Antibody

Pricing & Availability
Clone
17A2 (See other available formats)
Regulatory Status
RUO
Other Names
T cell antigen receptor complex, T3
Isotype
Rat IgG2b, κ
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Product Citations
publications
17A2_PECy7_083105
C57BL/6 splenocytes stained with 17A2 PE/Cyanine7
  • 17A2_PECy7_083105
    C57BL/6 splenocytes stained with 17A2 PE/Cyanine7
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
100219 25 µg DKK624
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100220 100 µg DKK1474
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Description

CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
γδTCR-positive T-T hybridoma D1
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported application (for relevant formats) include: spatial biology (IBEX)1,2.

Application References
  1. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  2. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Luo J, et al. 2022. J Nanobiotechnology. 20:228. PubMed
  2. Ramos SA, et al. 2022. J Allergy Clin Immunol. 149:767. PubMed
  3. Friesen M, et al. 2022. Brain Pathol. 32:e13032. PubMed
  4. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  5. Millar FR, et al. 2022. Cell Rep. 41:111596. PubMed
  6. Tran TA, et al. 2022. Front Immunol. 13:1007285. PubMed
  7. Lee CY, et al. 2022. J Invest Dermatol. :. PubMed
  8. Phares TW, et al. 2022. Front Pharmacol. 13:1029636. PubMed
  9. Montilla A, et al. 2023. Cell Death Dis. 14:16. PubMed
  10. Zhu X, et al. 2023. Front Immunol. 14:1114802. PubMed
  11. Ryan CB, et al. 2022. Neurobiol Dis. 163:105608. PubMed
  12. Georgiev GI, et al. 2022. Cell Chem Biol. 29:811. PubMed
  13. Xiao R, et al. 2022. J Immunol. 208:2109. PubMed
  14. Ramdas B, et al. 2022. Mol Ther. 30:2505. PubMed
  15. Sanmarco LM, et al. 2022. Nature. 611:801. PubMed
  16. Barsheshet Y, et al. 2022. Int J Mol Sci. 23:. PubMed
  17. Swan SL, et al. 2023. Front Immunol. 14:1085547. PubMed
  18. Sakae H, et al. 2023. Cells. 12:. PubMed
  19. Dona MSI, et al. 2023. Basic Res Cardiol. 118:11. PubMed
  20. Zhang YT, et al. 2023. Front Immunol. 14:1085456. PubMed
  21. Bhaskar A, et al. 2023. iScience. 26:106644. PubMed
  22. Wang Y, et al. 2023. iScience. 26:106630. PubMed
  23. Nguyen T, et al. 2023. Nat Commun. 14:3357. PubMed
  24. Bruggemann TR, et al. 2022. iScience. 25:105185. PubMed
  25. Djokić V, et al. 2019. Front Immunol. 9:2891. PubMed
  26. Koyama M, et al. 2015. J Exp Med. 212: 1303 - 1321. PubMed
  27. Ho J, et al. 2016. PLoS Biol. 14:e2000117. PubMed
  28. Xiao C, et al. 2021. Front Pharmacol. 12:721273. PubMed
  29. Qi Z, et al. 2022. Nat Commun. 13:182. PubMed
  30. d'Errico P, et al. 2021. Nat Neurosci. Online ahead of print. PubMed
  31. Schneider C, et al. 2018. Cell. 174:271. PubMed
  32. Page N, et al. 2018. Immunity. 48:937. PubMed
  33. Vacca M, et al. 2017. Front Immunol. . 10.3389/fimmu.2017.01462. PubMed
  34. Jacoby E, et al. 2021. NPJ Regen Med. 6:58. PubMed
  35. Ercoli G, et al. 2021. Front Immunol. 11:611661. PubMed
  36. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  37. Chen S, et al. 2022. Cancer Discov. :. PubMed
  38. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  39. Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
  40. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  41. Pan Y, et al. 2021. Front Cell Neurosci. 15:664312. PubMed
  42. De Vlaeminck Y, et al. 2020. Cancers (Basel). 12:. PubMed
  43. Liang Y, et al. 2020. J Immunol. 204:2984. PubMed
  44. Tilstam PV, et al. 2021. J Clin Invest. 131:. PubMed
  45. Feizi N, et al. 2021. Cell Death Dis. 12:1026. PubMed
  46. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  47. Tian X, et al. 2022. Front Immunol. 13:875236. PubMed
  48. Chan YH, et al. 2019. EMBO Mol Med. 11:e10092. PubMed
  49. LaFleur MW, et al. 2019. Nat Immunol. 20:1335. PubMed
  50. Patnode M, et al. 2013. J Biol Chem. 288:26533. PubMed
  51. Inoue D, et al. 2021. Nat Genet. 53:707. PubMed
  52. Tanner MA, et al. 2021. Am J Physiol Heart Circ Physiol. 321:H633. PubMed
  53. Jia L, et al. 2022. Front Immunol. 13:897879. PubMed
  54. Wang C, et al. 2021. Cell Rep. 37:110021. PubMed
  55. Campana L, et al. 2018. J Immunol. 200:1169. PubMed
  56. Green CD et al. 2018. Developmental cell. 46(5):651-667 . PubMed
  57. Yu AI, et al. 2020. Cell Rep. 107471:31. PubMed
  58. Dieterich LC, et al. 2019. International Journal of Cancer. 145(10):2804-2815. PubMed
  59. Chew W, et al. 2016. Nat Methods. 13: 868-874. PubMed
  60. Luan HH et al. 2019. Cell. 178(5):1231-1244 . PubMed
  61. Mooney J, et al. 2015. Sci Rep. 5: 14603. PubMed
  62. Wang F, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:257. PubMed
  63. Taube C, et al. 2011. PLoS One. 6:e21799. PubMed
  64. Miska J et al. 2019. Cell reports. 27(1):226-237 . PubMed
  65. Chen X et al. 2017. Cell stem cell. 21(6):747-760 . PubMed
  66. Chen D, et al. 2020. Cancer Immunol Res. 8:883. PubMed
  67. Wessel AW, et al. 2020. Nat Commun. 4.123611111. PubMed
  68. Garcia LR, et al. 2021. Nat Commun. 12:3364. PubMed
  69. Hu Y, et al. 2022. J Nanobiotechnology. 20:417. PubMed
  70. Ullah I, et al. 2021. Immunity. 54:2143. PubMed
  71. Bergin SM, et al. 2021. Brain Behav Immun. 95:477. PubMed
  72. Luo J, et al. 2022. J Nanobiotechnology. 20:228. PubMed
  73. Kishore M et al. 2017. Immunity. 47(5):875-889 . PubMed
  74. Yadava K et al. 2019. Elife. 8 pii: e44821. PubMed
  75. Kulkarni R, et al. 2021. PLoS One. 16:e0257191. PubMed
  76. Reinfeld BI, et al. 2021. Nature. 593:282. PubMed
  77. Mulas F, et al. 2020. Cell Mol Immunol. . PubMed
  78. De Veirman K, et al. 2021. Oncoimmunology. 10:2000699. PubMed
  79. Jiang Y, et al. 2020. Adv Mater. 32:e2001808. PubMed
  80. Shannon JP, et al. 2021. STAR Protoc. 2:100790. PubMed
  81. Li Z, et al. 2018. Front Immunol. 9:347. PubMed
  82. LaFleur MW, et al. 2019. Nat Commun. 10:1668. PubMed
  83. Zeng W, et al. 2021. STAR Protocols. 2(1):100361. PubMed
  84. Yazlovitskaya EM, et al. 2021. J Cell Sci. 134:. PubMed
  85. Yang R, et al. 2022. J Adv Res. 35:259. PubMed
  86. Song P, et al. 2018. Int J Mol Med. 41:935. PubMed
  87. Shannon JP, et al. 2021. Immunity. 54(2):276-290.e5. PubMed
  88. Oguri Y, et al. 2020. Cell. 182(3):563-577.e20. PubMed
  89. M H, et al. 2016. Sci Rep. 6: 20588. PubMed
  90. Spix B, et al. 2022. Nat Commun. 13:318. PubMed
  91. Goldstein JM et al. 2019. Cell reports. 27(4):1254-1264 . PubMed
  92. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  93. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  94. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  95. Wieghofer P, et al. 2021. EMBO J. 40:e105123. PubMed
  96. Chitu V, et al. 2020. Cell Reports. 30(9):3004-3019. PubMed
  97. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  98. Marcandalli J et al. 2019. Cell. 176(6):1420-1431 . PubMed
  99. Chen Z, et al. 2019. Mol Med Rep. 19:3210. PubMed
  100. Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
  101. Glasenapp A, et al. 2021. Circ Res. 129:369. PubMed
  102. Haase P, et al. 2020. Eur J Immunol. 50:558. PubMed
  103. Chakraborty M, et al. 2021. Cell Reports. 34(2):108609. PubMed
  104. Li E, et al. 2021. Front Immunol. 12:667177. PubMed
  105. Kung YJ, et al. 2022. J Biomed Sci. 29:57. PubMed
  106. Namkoong H, et al. 2018. PLoS Pathog. 14:e1006955. PubMed
  107. Akoolo L, et al. 2021. Cell Microbiol. 23:e13350. PubMed
  108. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  109. Zhao Y, et al. 2020. Front Immunol. 2.572222222. PubMed
  110. Yin X, et al. 2020. Cell Rep. 33:108278. PubMed
  111. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  112. Eastman AE, et al. 2020. Cell Rep. 31:107804. PubMed
  113. Reed-Geaghan EG, et al. 2020. J Exp Med. 217:00:00. PubMed
  114. Mathewson ND, et al. 2021. Cell. 184(5):1281-1298.e26. PubMed
  115. Wawrzyniak M, et al. 2021. Pharmacol Res Perspect. 9:e00837. PubMed
  116. Li H, et al. 2022. iScience. 25:104481. PubMed
  117. Catrysse L, et al. 2021. Cell Rep. 36:109748. PubMed
  118. Carson W, et al. 2011. PLoS One. 6:e20385. PubMed
  119. Spevak CC, et al. 2020. Cell Stem Cell. 26(5):755-765. PubMed
  120. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  121. Tseng SH, et al. 2021. J Biomed Sci. 28:63. PubMed
  122. Hohsfield LA, et al. 2021. Elife. 10:. PubMed
  123. Luo J, et al. 2022. J Nanobiotechnology. 20:228. PubMed
  124. Ramos SA, et al. 2022. J Allergy Clin Immunol. 149:767. PubMed
  125. Friesen M, et al. 2022. Brain Pathol. 32:e13032. PubMed
  126. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  127. Millar FR, et al. 2022. Cell Rep. 41:111596. PubMed
  128. Tran TA, et al. 2022. Front Immunol. 13:1007285. PubMed
  129. Lee CY, et al. 2022. J Invest Dermatol. :. PubMed
  130. Phares TW, et al. 2022. Front Pharmacol. 13:1029636. PubMed
  131. Montilla A, et al. 2023. Cell Death Dis. 14:16. PubMed
  132. Zhu X, et al. 2023. Front Immunol. 14:1114802. PubMed
  133. Ryan CB, et al. 2022. Neurobiol Dis. 163:105608. PubMed
  134. Georgiev GI, et al. 2022. Cell Chem Biol. 29:811. PubMed
  135. Xiao R, et al. 2022. J Immunol. 208:2109. PubMed
  136. Ramdas B, et al. 2022. Mol Ther. 30:2505. PubMed
  137. Sanmarco LM, et al. 2022. Nature. 611:801. PubMed
  138. Barsheshet Y, et al. 2022. Int J Mol Sci. 23:. PubMed
  139. Swan SL, et al. 2023. Front Immunol. 14:1085547. PubMed
  140. Sakae H, et al. 2023. Cells. 12:. PubMed
  141. Dona MSI, et al. 2023. Basic Res Cardiol. 118:11. PubMed
  142. Zhang YT, et al. 2023. Front Immunol. 14:1085456. PubMed
  143. Bhaskar A, et al. 2023. iScience. 26:106644. PubMed
  144. Wang Y, et al. 2023. iScience. 26:106630. PubMed
  145. Nguyen T, et al. 2023. Nat Commun. 14:3357. PubMed
  146. Bruggemann TR, et al. 2022. iScience. 25:105185. PubMed
  147. Djokić V, et al. 2019. Front Immunol. 9:2891. PubMed
  148. Koyama M, et al. 2015. J Exp Med. 212: 1303 - 1321. PubMed
  149. Ho J, et al. 2016. PLoS Biol. 14:e2000117. PubMed
  150. Xiao C, et al. 2021. Front Pharmacol. 12:721273. PubMed
  151. Qi Z, et al. 2022. Nat Commun. 13:182. PubMed
  152. d'Errico P, et al. 2021. Nat Neurosci. Online ahead of print. PubMed
  153. Schneider C, et al. 2018. Cell. 174:271. PubMed
  154. Page N, et al. 2018. Immunity. 48:937. PubMed
  155. Vacca M, et al. 2017. Front Immunol. . 10.3389/fimmu.2017.01462. PubMed
  156. Jacoby E, et al. 2021. NPJ Regen Med. 6:58. PubMed
  157. Ercoli G, et al. 2021. Front Immunol. 11:611661. PubMed
  158. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  159. Chen S, et al. 2022. Cancer Discov. :. PubMed
  160. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  161. Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
  162. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  163. Pan Y, et al. 2021. Front Cell Neurosci. 15:664312. PubMed
  164. De Vlaeminck Y, et al. 2020. Cancers (Basel). 12:. PubMed
  165. Liang Y, et al. 2020. J Immunol. 204:2984. PubMed
  166. Tilstam PV, et al. 2021. J Clin Invest. 131:. PubMed
  167. Feizi N, et al. 2021. Cell Death Dis. 12:1026. PubMed
  168. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  169. Tian X, et al. 2022. Front Immunol. 13:875236. PubMed
  170. Chan YH, et al. 2019. EMBO Mol Med. 11:e10092. PubMed
  171. LaFleur MW, et al. 2019. Nat Immunol. 20:1335. PubMed
  172. Patnode M, et al. 2013. J Biol Chem. 288:26533. PubMed
  173. Inoue D, et al. 2021. Nat Genet. 53:707. PubMed
  174. Tanner MA, et al. 2021. Am J Physiol Heart Circ Physiol. 321:H633. PubMed
  175. Jia L, et al. 2022. Front Immunol. 13:897879. PubMed
  176. Wang C, et al. 2021. Cell Rep. 37:110021. PubMed
  177. Campana L, et al. 2018. J Immunol. 200:1169. PubMed
  178. Green CD et al. 2018. Developmental cell. 46(5):651-667 . PubMed
  179. Yu AI, et al. 2020. Cell Rep. 107471:31. PubMed
  180. Dieterich LC, et al. 2019. International Journal of Cancer. 145(10):2804-2815. PubMed
  181. Chew W, et al. 2016. Nat Methods. 13: 868-874. PubMed
  182. Luan HH et al. 2019. Cell. 178(5):1231-1244 . PubMed
  183. Mooney J, et al. 2015. Sci Rep. 5: 14603. PubMed
  184. Wang F, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:257. PubMed
  185. Taube C, et al. 2011. PLoS One. 6:e21799. PubMed
  186. Miska J et al. 2019. Cell reports. 27(1):226-237 . PubMed
  187. Chen X et al. 2017. Cell stem cell. 21(6):747-760 . PubMed
  188. Chen D, et al. 2020. Cancer Immunol Res. 8:883. PubMed
  189. Wessel AW, et al. 2020. Nat Commun. 4.123611111. PubMed
  190. Garcia LR, et al. 2021. Nat Commun. 12:3364. PubMed
  191. Hu Y, et al. 2022. J Nanobiotechnology. 20:417. PubMed
  192. Ullah I, et al. 2021. Immunity. 54:2143. PubMed
  193. Bergin SM, et al. 2021. Brain Behav Immun. 95:477. PubMed
  194. Luo J, et al. 2022. J Nanobiotechnology. 20:228. PubMed
  195. Kishore M et al. 2017. Immunity. 47(5):875-889 . PubMed
  196. Yadava K et al. 2019. Elife. 8 pii: e44821. PubMed
  197. Kulkarni R, et al. 2021. PLoS One. 16:e0257191. PubMed
  198. Reinfeld BI, et al. 2021. Nature. 593:282. PubMed
  199. Mulas F, et al. 2020. Cell Mol Immunol. . PubMed
  200. De Veirman K, et al. 2021. Oncoimmunology. 10:2000699. PubMed
  201. Jiang Y, et al. 2020. Adv Mater. 32:e2001808. PubMed
  202. Shannon JP, et al. 2021. STAR Protoc. 2:100790. PubMed
  203. Li Z, et al. 2018. Front Immunol. 9:347. PubMed
  204. LaFleur MW, et al. 2019. Nat Commun. 10:1668. PubMed
  205. Zeng W, et al. 2021. STAR Protocols. 2(1):100361. PubMed
  206. Yazlovitskaya EM, et al. 2021. J Cell Sci. 134:. PubMed
  207. Yang R, et al. 2022. J Adv Res. 35:259. PubMed
  208. Song P, et al. 2018. Int J Mol Med. 41:935. PubMed
  209. Shannon JP, et al. 2021. Immunity. 54(2):276-290.e5. PubMed
  210. Oguri Y, et al. 2020. Cell. 182(3):563-577.e20. PubMed
  211. M H, et al. 2016. Sci Rep. 6: 20588. PubMed
  212. Spix B, et al. 2022. Nat Commun. 13:318. PubMed
  213. Goldstein JM et al. 2019. Cell reports. 27(4):1254-1264 . PubMed
  214. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  215. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  216. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  217. Wieghofer P, et al. 2021. EMBO J. 40:e105123. PubMed
  218. Chitu V, et al. 2020. Cell Reports. 30(9):3004-3019. PubMed
  219. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  220. Marcandalli J et al. 2019. Cell. 176(6):1420-1431 . PubMed
  221. Chen Z, et al. 2019. Mol Med Rep. 19:3210. PubMed
  222. Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
  223. Glasenapp A, et al. 2021. Circ Res. 129:369. PubMed
  224. Haase P, et al. 2020. Eur J Immunol. 50:558. PubMed
  225. Chakraborty M, et al. 2021. Cell Reports. 34(2):108609. PubMed
  226. Li E, et al. 2021. Front Immunol. 12:667177. PubMed
  227. Kung YJ, et al. 2022. J Biomed Sci. 29:57. PubMed
  228. Namkoong H, et al. 2018. PLoS Pathog. 14:e1006955. PubMed
  229. Akoolo L, et al. 2021. Cell Microbiol. 23:e13350. PubMed
  230. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  231. Zhao Y, et al. 2020. Front Immunol. 2.572222222. PubMed
  232. Yin X, et al. 2020. Cell Rep. 33:108278. PubMed
  233. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  234. Eastman AE, et al. 2020. Cell Rep. 31:107804. PubMed
  235. Reed-Geaghan EG, et al. 2020. J Exp Med. 217:00:00. PubMed
  236. Mathewson ND, et al. 2021. Cell. 184(5):1281-1298.e26. PubMed
  237. Wawrzyniak M, et al. 2021. Pharmacol Res Perspect. 9:e00837. PubMed
  238. Li H, et al. 2022. iScience. 25:104481. PubMed
  239. Catrysse L, et al. 2021. Cell Rep. 36:109748. PubMed
  240. Carson W, et al. 2011. PLoS One. 6:e20385. PubMed
  241. Spevak CC, et al. 2020. Cell Stem Cell. 26(5):755-765. PubMed
  242. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  243. Tseng SH, et al. 2021. J Biomed Sci. 28:63. PubMed
  244. Hohsfield LA, et al. 2021. Elife. 10:. PubMed
RRID
AB_1732068 (BioLegend Cat. No. 100219)
AB_1732057 (BioLegend Cat. No. 100220)

Antigen Details

Structure
Ig superfamily, CD3/TCR, 20 kD
Distribution

Thymocytes (differentiation dependent), mature T cells, NK-T cells

Function
Antigen recognition, TCR signal transduction, T cell activation
Ligand/Receptor
Peptide antigen/MHC-complex
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Davis MM. 1990. Annu. Rev. Biochem. 59:475.
3. Weiss A, et al. 1994. Cell 76:263.

Gene ID
12502 View all products for this Gene ID
UniProt
View information about CD3 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

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Description Clone Applications
Brilliant Violet 711™ anti-mouse CD3 17A2 FC
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APC/Fire™ 750 anti-mouse CD3 17A2 FC
Brilliant Violet 750™ anti-mouse CD3 17A2 FC
TotalSeq™-A0182 anti-mouse CD3 17A2 PG
TotalSeq™-B0182 anti-mouse CD3 17A2 PG
Spark Blue™ 550 anti-mouse CD3 17A2 FC
Spark NIR™ 685 anti-mouse CD3 17A2 FC
TotalSeq™-C0182 anti-mouse CD3 17A2 PG
APC/Fire™ 810 anti-mouse CD3 17A2 FC
PE/Fire™ 640 anti-mouse CD3 17A2 FC
Spark YG™ 570 anti-mouse CD3 17A2 IHC-F
PE/Fire™ 700 anti-mouse CD3 17A2 FC
Test 17A2 5 17A2
FITC anti-mouse CD3 17A2 FC
PE anti-mouse CD3 17A2 FC
Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Alexa Fluor® 647 anti-mouse CD3 17A2 FC,IHC-F,3D IHC,SB
Alexa Fluor® 488 anti-mouse CD3 17A2 FC,IHC-F,3D IHC
Pacific Blue™ anti-mouse CD3 17A2 FC
Alexa Fluor® 700 anti-mouse CD3 17A2 FC
PerCP/Cyanine5.5 anti-mouse CD3 17A2 FC
PE/Cyanine7 anti-mouse CD3 17A2 FC
APC/Cyanine7 anti-mouse CD3 17A2 FC
Brilliant Violet 421™ anti-mouse CD3 17A2 FC,ICC
Brilliant Violet 570™ anti-mouse CD3 17A2 FC
Brilliant Violet 650™ anti-mouse CD3 17A2 FC
Brilliant Violet 785™ anti-mouse CD3 17A2 FC
Brilliant Violet 510™ anti-mouse CD3 17A2 FC
APC anti-mouse CD3 17A2 FC
Ultra-LEAF™ Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Brilliant Violet 605™ anti-mouse CD3 17A2 FC
Alexa Fluor® 594 anti-mouse CD3 17A2 IHC-F,FC,3D IHC,SB
PE/Cyanine5 anti-mouse CD3 17A2 FC
Spark Blue™ 574 anti-mouse CD3 Antibody 17A2 FC
Spark Violet™ 423 anti-mouse CD3 17A2 FC
PE/Fire™ 810 anti-mouse CD3 17A2 FC
Spark Red™ 718 anti-mouse CD3 17A2 FC
Spark UV™ 387 anti-mouse CD3 17A2 FC
PerCP/Fire™ 780 anti-mouse CD3 Antibody 17A2 FC
PerCP anti-mouse CD3 Antibody 17A2 FC
Spark YG™ 581 anti-mouse CD3 (Flexi-Fluor™) 17A2 FC
Spark YG™ 593 anti-mouse CD3 (Flexi-Fluor™) Antibody 17A2 FC
Spark PLUS B488™ anti-mouse CD3 17A2 FC
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Pricing & Availability
Clone
17A2 (See other available formats)
Regulatory Status
RUO
Other Names
T cell antigen receptor complex, T3
Isotype
Rat IgG2b, κ
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Product Citations
publications
17A2_PECy7_083105
C57BL/6 splenocytes stained with 17A2 PE/Cyanine7
  • 17A2_PECy7_083105
    C57BL/6 splenocytes stained with 17A2 PE/Cyanine7
Compare all formats See PE/Cyanine7 spectral data
Cat # Size Price Quantity Check Availability Save
100219 25 µg DKK624
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100220 100 µg DKK1474
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Description

CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
γδTCR-positive T-T hybridoma D1
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported application (for relevant formats) include: spatial biology (IBEX)1,2.

Application References
  1. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  2. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Luo J, et al. 2022. J Nanobiotechnology. 20:228. PubMed
  2. Ramos SA, et al. 2022. J Allergy Clin Immunol. 149:767. PubMed
  3. Friesen M, et al. 2022. Brain Pathol. 32:e13032. PubMed
  4. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  5. Millar FR, et al. 2022. Cell Rep. 41:111596. PubMed
  6. Tran TA, et al. 2022. Front Immunol. 13:1007285. PubMed
  7. Lee CY, et al. 2022. J Invest Dermatol. :. PubMed
  8. Phares TW, et al. 2022. Front Pharmacol. 13:1029636. PubMed
  9. Montilla A, et al. 2023. Cell Death Dis. 14:16. PubMed
  10. Zhu X, et al. 2023. Front Immunol. 14:1114802. PubMed
  11. Ryan CB, et al. 2022. Neurobiol Dis. 163:105608. PubMed
  12. Georgiev GI, et al. 2022. Cell Chem Biol. 29:811. PubMed
  13. Xiao R, et al. 2022. J Immunol. 208:2109. PubMed
  14. Ramdas B, et al. 2022. Mol Ther. 30:2505. PubMed
  15. Sanmarco LM, et al. 2022. Nature. 611:801. PubMed
  16. Barsheshet Y, et al. 2022. Int J Mol Sci. 23:. PubMed
  17. Swan SL, et al. 2023. Front Immunol. 14:1085547. PubMed
  18. Sakae H, et al. 2023. Cells. 12:. PubMed
  19. Dona MSI, et al. 2023. Basic Res Cardiol. 118:11. PubMed
  20. Zhang YT, et al. 2023. Front Immunol. 14:1085456. PubMed
  21. Bhaskar A, et al. 2023. iScience. 26:106644. PubMed
  22. Wang Y, et al. 2023. iScience. 26:106630. PubMed
  23. Nguyen T, et al. 2023. Nat Commun. 14:3357. PubMed
  24. Bruggemann TR, et al. 2022. iScience. 25:105185. PubMed
  25. Djokić V, et al. 2019. Front Immunol. 9:2891. PubMed
  26. Koyama M, et al. 2015. J Exp Med. 212: 1303 - 1321. PubMed
  27. Ho J, et al. 2016. PLoS Biol. 14:e2000117. PubMed
  28. Xiao C, et al. 2021. Front Pharmacol. 12:721273. PubMed
  29. Qi Z, et al. 2022. Nat Commun. 13:182. PubMed
  30. d'Errico P, et al. 2021. Nat Neurosci. Online ahead of print. PubMed
  31. Schneider C, et al. 2018. Cell. 174:271. PubMed
  32. Page N, et al. 2018. Immunity. 48:937. PubMed
  33. Vacca M, et al. 2017. Front Immunol. . 10.3389/fimmu.2017.01462. PubMed
  34. Jacoby E, et al. 2021. NPJ Regen Med. 6:58. PubMed
  35. Ercoli G, et al. 2021. Front Immunol. 11:611661. PubMed
  36. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  37. Chen S, et al. 2022. Cancer Discov. :. PubMed
  38. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  39. Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
  40. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  41. Pan Y, et al. 2021. Front Cell Neurosci. 15:664312. PubMed
  42. De Vlaeminck Y, et al. 2020. Cancers (Basel). 12:. PubMed
  43. Liang Y, et al. 2020. J Immunol. 204:2984. PubMed
  44. Tilstam PV, et al. 2021. J Clin Invest. 131:. PubMed
  45. Feizi N, et al. 2021. Cell Death Dis. 12:1026. PubMed
  46. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  47. Tian X, et al. 2022. Front Immunol. 13:875236. PubMed
  48. Chan YH, et al. 2019. EMBO Mol Med. 11:e10092. PubMed
  49. LaFleur MW, et al. 2019. Nat Immunol. 20:1335. PubMed
  50. Patnode M, et al. 2013. J Biol Chem. 288:26533. PubMed
  51. Inoue D, et al. 2021. Nat Genet. 53:707. PubMed
  52. Tanner MA, et al. 2021. Am J Physiol Heart Circ Physiol. 321:H633. PubMed
  53. Jia L, et al. 2022. Front Immunol. 13:897879. PubMed
  54. Wang C, et al. 2021. Cell Rep. 37:110021. PubMed
  55. Campana L, et al. 2018. J Immunol. 200:1169. PubMed
  56. Green CD et al. 2018. Developmental cell. 46(5):651-667 . PubMed
  57. Yu AI, et al. 2020. Cell Rep. 107471:31. PubMed
  58. Dieterich LC, et al. 2019. International Journal of Cancer. 145(10):2804-2815. PubMed
  59. Chew W, et al. 2016. Nat Methods. 13: 868-874. PubMed
  60. Luan HH et al. 2019. Cell. 178(5):1231-1244 . PubMed
  61. Mooney J, et al. 2015. Sci Rep. 5: 14603. PubMed
  62. Wang F, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:257. PubMed
  63. Taube C, et al. 2011. PLoS One. 6:e21799. PubMed
  64. Miska J et al. 2019. Cell reports. 27(1):226-237 . PubMed
  65. Chen X et al. 2017. Cell stem cell. 21(6):747-760 . PubMed
  66. Chen D, et al. 2020. Cancer Immunol Res. 8:883. PubMed
  67. Wessel AW, et al. 2020. Nat Commun. 4.123611111. PubMed
  68. Garcia LR, et al. 2021. Nat Commun. 12:3364. PubMed
  69. Hu Y, et al. 2022. J Nanobiotechnology. 20:417. PubMed
  70. Ullah I, et al. 2021. Immunity. 54:2143. PubMed
  71. Bergin SM, et al. 2021. Brain Behav Immun. 95:477. PubMed
  72. Luo J, et al. 2022. J Nanobiotechnology. 20:228. PubMed
  73. Kishore M et al. 2017. Immunity. 47(5):875-889 . PubMed
  74. Yadava K et al. 2019. Elife. 8 pii: e44821. PubMed
  75. Kulkarni R, et al. 2021. PLoS One. 16:e0257191. PubMed
  76. Reinfeld BI, et al. 2021. Nature. 593:282. PubMed
  77. Mulas F, et al. 2020. Cell Mol Immunol. . PubMed
  78. De Veirman K, et al. 2021. Oncoimmunology. 10:2000699. PubMed
  79. Jiang Y, et al. 2020. Adv Mater. 32:e2001808. PubMed
  80. Shannon JP, et al. 2021. STAR Protoc. 2:100790. PubMed
  81. Li Z, et al. 2018. Front Immunol. 9:347. PubMed
  82. LaFleur MW, et al. 2019. Nat Commun. 10:1668. PubMed
  83. Zeng W, et al. 2021. STAR Protocols. 2(1):100361. PubMed
  84. Yazlovitskaya EM, et al. 2021. J Cell Sci. 134:. PubMed
  85. Yang R, et al. 2022. J Adv Res. 35:259. PubMed
  86. Song P, et al. 2018. Int J Mol Med. 41:935. PubMed
  87. Shannon JP, et al. 2021. Immunity. 54(2):276-290.e5. PubMed
  88. Oguri Y, et al. 2020. Cell. 182(3):563-577.e20. PubMed
  89. M H, et al. 2016. Sci Rep. 6: 20588. PubMed
  90. Spix B, et al. 2022. Nat Commun. 13:318. PubMed
  91. Goldstein JM et al. 2019. Cell reports. 27(4):1254-1264 . PubMed
  92. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  93. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  94. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  95. Wieghofer P, et al. 2021. EMBO J. 40:e105123. PubMed
  96. Chitu V, et al. 2020. Cell Reports. 30(9):3004-3019. PubMed
  97. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  98. Marcandalli J et al. 2019. Cell. 176(6):1420-1431 . PubMed
  99. Chen Z, et al. 2019. Mol Med Rep. 19:3210. PubMed
  100. Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
  101. Glasenapp A, et al. 2021. Circ Res. 129:369. PubMed
  102. Haase P, et al. 2020. Eur J Immunol. 50:558. PubMed
  103. Chakraborty M, et al. 2021. Cell Reports. 34(2):108609. PubMed
  104. Li E, et al. 2021. Front Immunol. 12:667177. PubMed
  105. Kung YJ, et al. 2022. J Biomed Sci. 29:57. PubMed
  106. Namkoong H, et al. 2018. PLoS Pathog. 14:e1006955. PubMed
  107. Akoolo L, et al. 2021. Cell Microbiol. 23:e13350. PubMed
  108. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  109. Zhao Y, et al. 2020. Front Immunol. 2.572222222. PubMed
  110. Yin X, et al. 2020. Cell Rep. 33:108278. PubMed
  111. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  112. Eastman AE, et al. 2020. Cell Rep. 31:107804. PubMed
  113. Reed-Geaghan EG, et al. 2020. J Exp Med. 217:00:00. PubMed
  114. Mathewson ND, et al. 2021. Cell. 184(5):1281-1298.e26. PubMed
  115. Wawrzyniak M, et al. 2021. Pharmacol Res Perspect. 9:e00837. PubMed
  116. Li H, et al. 2022. iScience. 25:104481. PubMed
  117. Catrysse L, et al. 2021. Cell Rep. 36:109748. PubMed
  118. Carson W, et al. 2011. PLoS One. 6:e20385. PubMed
  119. Spevak CC, et al. 2020. Cell Stem Cell. 26(5):755-765. PubMed
  120. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  121. Tseng SH, et al. 2021. J Biomed Sci. 28:63. PubMed
  122. Hohsfield LA, et al. 2021. Elife. 10:. PubMed
  123. Luo J, et al. 2022. J Nanobiotechnology. 20:228. PubMed
  124. Ramos SA, et al. 2022. J Allergy Clin Immunol. 149:767. PubMed
  125. Friesen M, et al. 2022. Brain Pathol. 32:e13032. PubMed
  126. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  127. Millar FR, et al. 2022. Cell Rep. 41:111596. PubMed
  128. Tran TA, et al. 2022. Front Immunol. 13:1007285. PubMed
  129. Lee CY, et al. 2022. J Invest Dermatol. :. PubMed
  130. Phares TW, et al. 2022. Front Pharmacol. 13:1029636. PubMed
  131. Montilla A, et al. 2023. Cell Death Dis. 14:16. PubMed
  132. Zhu X, et al. 2023. Front Immunol. 14:1114802. PubMed
  133. Ryan CB, et al. 2022. Neurobiol Dis. 163:105608. PubMed
  134. Georgiev GI, et al. 2022. Cell Chem Biol. 29:811. PubMed
  135. Xiao R, et al. 2022. J Immunol. 208:2109. PubMed
  136. Ramdas B, et al. 2022. Mol Ther. 30:2505. PubMed
  137. Sanmarco LM, et al. 2022. Nature. 611:801. PubMed
  138. Barsheshet Y, et al. 2022. Int J Mol Sci. 23:. PubMed
  139. Swan SL, et al. 2023. Front Immunol. 14:1085547. PubMed
  140. Sakae H, et al. 2023. Cells. 12:. PubMed
  141. Dona MSI, et al. 2023. Basic Res Cardiol. 118:11. PubMed
  142. Zhang YT, et al. 2023. Front Immunol. 14:1085456. PubMed
  143. Bhaskar A, et al. 2023. iScience. 26:106644. PubMed
  144. Wang Y, et al. 2023. iScience. 26:106630. PubMed
  145. Nguyen T, et al. 2023. Nat Commun. 14:3357. PubMed
  146. Bruggemann TR, et al. 2022. iScience. 25:105185. PubMed
  147. Djokić V, et al. 2019. Front Immunol. 9:2891. PubMed
  148. Koyama M, et al. 2015. J Exp Med. 212: 1303 - 1321. PubMed
  149. Ho J, et al. 2016. PLoS Biol. 14:e2000117. PubMed
  150. Xiao C, et al. 2021. Front Pharmacol. 12:721273. PubMed
  151. Qi Z, et al. 2022. Nat Commun. 13:182. PubMed
  152. d'Errico P, et al. 2021. Nat Neurosci. Online ahead of print. PubMed
  153. Schneider C, et al. 2018. Cell. 174:271. PubMed
  154. Page N, et al. 2018. Immunity. 48:937. PubMed
  155. Vacca M, et al. 2017. Front Immunol. . 10.3389/fimmu.2017.01462. PubMed
  156. Jacoby E, et al. 2021. NPJ Regen Med. 6:58. PubMed
  157. Ercoli G, et al. 2021. Front Immunol. 11:611661. PubMed
  158. Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
  159. Chen S, et al. 2022. Cancer Discov. :. PubMed
  160. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  161. Mogilenko DA, et al. 2020. Immunity. 54(1):99-115.e12. PubMed
  162. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  163. Pan Y, et al. 2021. Front Cell Neurosci. 15:664312. PubMed
  164. De Vlaeminck Y, et al. 2020. Cancers (Basel). 12:. PubMed
  165. Liang Y, et al. 2020. J Immunol. 204:2984. PubMed
  166. Tilstam PV, et al. 2021. J Clin Invest. 131:. PubMed
  167. Feizi N, et al. 2021. Cell Death Dis. 12:1026. PubMed
  168. Yuzhu Hou et al. 2018. Immunity. 49(3):490-503 . PubMed
  169. Tian X, et al. 2022. Front Immunol. 13:875236. PubMed
  170. Chan YH, et al. 2019. EMBO Mol Med. 11:e10092. PubMed
  171. LaFleur MW, et al. 2019. Nat Immunol. 20:1335. PubMed
  172. Patnode M, et al. 2013. J Biol Chem. 288:26533. PubMed
  173. Inoue D, et al. 2021. Nat Genet. 53:707. PubMed
  174. Tanner MA, et al. 2021. Am J Physiol Heart Circ Physiol. 321:H633. PubMed
  175. Jia L, et al. 2022. Front Immunol. 13:897879. PubMed
  176. Wang C, et al. 2021. Cell Rep. 37:110021. PubMed
  177. Campana L, et al. 2018. J Immunol. 200:1169. PubMed
  178. Green CD et al. 2018. Developmental cell. 46(5):651-667 . PubMed
  179. Yu AI, et al. 2020. Cell Rep. 107471:31. PubMed
  180. Dieterich LC, et al. 2019. International Journal of Cancer. 145(10):2804-2815. PubMed
  181. Chew W, et al. 2016. Nat Methods. 13: 868-874. PubMed
  182. Luan HH et al. 2019. Cell. 178(5):1231-1244 . PubMed
  183. Mooney J, et al. 2015. Sci Rep. 5: 14603. PubMed
  184. Wang F, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:257. PubMed
  185. Taube C, et al. 2011. PLoS One. 6:e21799. PubMed
  186. Miska J et al. 2019. Cell reports. 27(1):226-237 . PubMed
  187. Chen X et al. 2017. Cell stem cell. 21(6):747-760 . PubMed
  188. Chen D, et al. 2020. Cancer Immunol Res. 8:883. PubMed
  189. Wessel AW, et al. 2020. Nat Commun. 4.123611111. PubMed
  190. Garcia LR, et al. 2021. Nat Commun. 12:3364. PubMed
  191. Hu Y, et al. 2022. J Nanobiotechnology. 20:417. PubMed
  192. Ullah I, et al. 2021. Immunity. 54:2143. PubMed
  193. Bergin SM, et al. 2021. Brain Behav Immun. 95:477. PubMed
  194. Luo J, et al. 2022. J Nanobiotechnology. 20:228. PubMed
  195. Kishore M et al. 2017. Immunity. 47(5):875-889 . PubMed
  196. Yadava K et al. 2019. Elife. 8 pii: e44821. PubMed
  197. Kulkarni R, et al. 2021. PLoS One. 16:e0257191. PubMed
  198. Reinfeld BI, et al. 2021. Nature. 593:282. PubMed
  199. Mulas F, et al. 2020. Cell Mol Immunol. . PubMed
  200. De Veirman K, et al. 2021. Oncoimmunology. 10:2000699. PubMed
  201. Jiang Y, et al. 2020. Adv Mater. 32:e2001808. PubMed
  202. Shannon JP, et al. 2021. STAR Protoc. 2:100790. PubMed
  203. Li Z, et al. 2018. Front Immunol. 9:347. PubMed
  204. LaFleur MW, et al. 2019. Nat Commun. 10:1668. PubMed
  205. Zeng W, et al. 2021. STAR Protocols. 2(1):100361. PubMed
  206. Yazlovitskaya EM, et al. 2021. J Cell Sci. 134:. PubMed
  207. Yang R, et al. 2022. J Adv Res. 35:259. PubMed
  208. Song P, et al. 2018. Int J Mol Med. 41:935. PubMed
  209. Shannon JP, et al. 2021. Immunity. 54(2):276-290.e5. PubMed
  210. Oguri Y, et al. 2020. Cell. 182(3):563-577.e20. PubMed
  211. M H, et al. 2016. Sci Rep. 6: 20588. PubMed
  212. Spix B, et al. 2022. Nat Commun. 13:318. PubMed
  213. Goldstein JM et al. 2019. Cell reports. 27(4):1254-1264 . PubMed
  214. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  215. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  216. Takaku S, et al. 2022. Evid Based Complement Alternat Med. 2022:6122955. PubMed
  217. Wieghofer P, et al. 2021. EMBO J. 40:e105123. PubMed
  218. Chitu V, et al. 2020. Cell Reports. 30(9):3004-3019. PubMed
  219. Burgener SS, et al. 2019. Cell Rep. 27:3646. PubMed
  220. Marcandalli J et al. 2019. Cell. 176(6):1420-1431 . PubMed
  221. Chen Z, et al. 2019. Mol Med Rep. 19:3210. PubMed
  222. Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
  223. Glasenapp A, et al. 2021. Circ Res. 129:369. PubMed
  224. Haase P, et al. 2020. Eur J Immunol. 50:558. PubMed
  225. Chakraborty M, et al. 2021. Cell Reports. 34(2):108609. PubMed
  226. Li E, et al. 2021. Front Immunol. 12:667177. PubMed
  227. Kung YJ, et al. 2022. J Biomed Sci. 29:57. PubMed
  228. Namkoong H, et al. 2018. PLoS Pathog. 14:e1006955. PubMed
  229. Akoolo L, et al. 2021. Cell Microbiol. 23:e13350. PubMed
  230. Chao JL, et al. 2021. Cell Rep Med. 2:100399. PubMed
  231. Zhao Y, et al. 2020. Front Immunol. 2.572222222. PubMed
  232. Yin X, et al. 2020. Cell Rep. 33:108278. PubMed
  233. Blaszczak AM, et al. 2020. Immunometabolism. 2:00. PubMed
  234. Eastman AE, et al. 2020. Cell Rep. 31:107804. PubMed
  235. Reed-Geaghan EG, et al. 2020. J Exp Med. 217:00:00. PubMed
  236. Mathewson ND, et al. 2021. Cell. 184(5):1281-1298.e26. PubMed
  237. Wawrzyniak M, et al. 2021. Pharmacol Res Perspect. 9:e00837. PubMed
  238. Li H, et al. 2022. iScience. 25:104481. PubMed
  239. Catrysse L, et al. 2021. Cell Rep. 36:109748. PubMed
  240. Carson W, et al. 2011. PLoS One. 6:e20385. PubMed
  241. Spevak CC, et al. 2020. Cell Stem Cell. 26(5):755-765. PubMed
  242. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  243. Tseng SH, et al. 2021. J Biomed Sci. 28:63. PubMed
  244. Hohsfield LA, et al. 2021. Elife. 10:. PubMed
RRID
AB_1732068 (BioLegend Cat. No. 100219)
AB_1732057 (BioLegend Cat. No. 100220)

Antigen Details

Structure
Ig superfamily, CD3/TCR, 20 kD
Distribution

Thymocytes (differentiation dependent), mature T cells, NK-T cells

Function
Antigen recognition, TCR signal transduction, T cell activation
Ligand/Receptor
Peptide antigen/MHC-complex
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Davis MM. 1990. Annu. Rev. Biochem. 59:475.
3. Weiss A, et al. 1994. Cell 76:263.

Gene ID
12502 View all products for this Gene ID
UniProt
View information about CD3 on UniProt.org

Other Formats

View All CD3 Reagents Request Custom Conjugation
Description Clone Applications
Brilliant Violet 711™ anti-mouse CD3 17A2 FC
Biotin anti-mouse CD3 17A2 FC,IHC-F
PE/Dazzle™ 594 anti-mouse CD3 17A2 FC
APC/Fire™ 750 anti-mouse CD3 17A2 FC
Brilliant Violet 750™ anti-mouse CD3 17A2 FC
TotalSeq™-A0182 anti-mouse CD3 17A2 PG
TotalSeq™-B0182 anti-mouse CD3 17A2 PG
Spark Blue™ 550 anti-mouse CD3 17A2 FC
Spark NIR™ 685 anti-mouse CD3 17A2 FC
TotalSeq™-C0182 anti-mouse CD3 17A2 PG
APC/Fire™ 810 anti-mouse CD3 17A2 FC
PE/Fire™ 640 anti-mouse CD3 17A2 FC
Spark YG™ 570 anti-mouse CD3 17A2 IHC-F
PE/Fire™ 700 anti-mouse CD3 17A2 FC
Test 17A2 5 17A2
FITC anti-mouse CD3 17A2 FC
PE anti-mouse CD3 17A2 FC
Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Alexa Fluor® 647 anti-mouse CD3 17A2 FC,IHC-F,3D IHC,SB
Alexa Fluor® 488 anti-mouse CD3 17A2 FC,IHC-F,3D IHC
Pacific Blue™ anti-mouse CD3 17A2 FC
Alexa Fluor® 700 anti-mouse CD3 17A2 FC
PerCP/Cyanine5.5 anti-mouse CD3 17A2 FC
PE/Cyanine7 anti-mouse CD3 17A2 FC
APC/Cyanine7 anti-mouse CD3 17A2 FC
Brilliant Violet 421™ anti-mouse CD3 17A2 FC,ICC
Brilliant Violet 570™ anti-mouse CD3 17A2 FC
Brilliant Violet 650™ anti-mouse CD3 17A2 FC
Brilliant Violet 785™ anti-mouse CD3 17A2 FC
Brilliant Violet 510™ anti-mouse CD3 17A2 FC
APC anti-mouse CD3 17A2 FC
Ultra-LEAF™ Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Brilliant Violet 605™ anti-mouse CD3 17A2 FC
Alexa Fluor® 594 anti-mouse CD3 17A2 IHC-F,FC,3D IHC,SB
PE/Cyanine5 anti-mouse CD3 17A2 FC
Spark Blue™ 574 anti-mouse CD3 Antibody 17A2 FC
Spark Violet™ 423 anti-mouse CD3 17A2 FC
PE/Fire™ 810 anti-mouse CD3 17A2 FC
Spark Red™ 718 anti-mouse CD3 17A2 FC
Spark UV™ 387 anti-mouse CD3 17A2 FC
PerCP/Fire™ 780 anti-mouse CD3 Antibody 17A2 FC
PerCP anti-mouse CD3 Antibody 17A2 FC
Spark YG™ 581 anti-mouse CD3 (Flexi-Fluor™) 17A2 FC
Spark YG™ 593 anti-mouse CD3 (Flexi-Fluor™) Antibody 17A2 FC
Spark PLUS B488™ anti-mouse CD3 17A2 FC
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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