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FITC anti-mouse CD45 Antibody FITC anti-mouse CD45 Antibody

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
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Product Citations
publications
30-f11
C57BL/6 splenocytes stained with 30-F11 FITC
  • 30-f11
    C57BL/6 splenocytes stained with 30-F11 FITC
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability Save
103107 50 µg DKK214
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103108 500 µg DKK624
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Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Application References
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  2. Xu X, et al. 2020. Chin Med. 15:33. PubMed
  3. Shakya S, et al. 2020. MethodsX. 7:101027. PubMed
  4. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  5. Kataru RP, et al. 2021. Sci Signal. 14:. PubMed
  6. Li Z, et al. 2022. Nat Commun. 13:1845. PubMed
  7. Li Y, et al. 2020. Nat Commun. 2.350694444. PubMed
  8. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  9. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  10. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  11. Johnson DC, et al. 2018. Nat Med. 24:1151. PubMed
  12. Sefik E, et al. 2022. Nature. 606:585. PubMed
  13. Leinroth AP, et al. 2022. Cell Rep. 39:110785. PubMed
  14. Doughty D, et al. 2022. Exp Biol Med (Maywood). 247:1433. PubMed
  15. Du M, et al. 2022. Cancer Sci. 113:2974. PubMed
  16. Grégoire C, et al. 2022. Immunity. 55:1216. PubMed
  17. Tao X, et al. 2022. EMBO J. 41:e110439. PubMed
  18. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  19. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  20. Hindy G, et al. 2022. J Clin Invest. 132: . PubMed
  21. Roy IM, et al. 2022. iScience. 25:105171. PubMed
  22. Mendivil-Perez M, et al. 2022. Med Oncol. 40:15. PubMed
  23. Chen X, et al. 2022. J Extracell Vesicles. 11:e12279. PubMed
  24. Zheng Z, et al. 2022. Cells. 11: . PubMed
  25. Voit RA, et al. 2023. Nat Immunol. 24:69. PubMed
  26. Varshney R, et al. 2023. iScience. 26:105750. PubMed
  27. Cheng P, et al. 2023. Pharmacol Res. 188:106643. PubMed
  28. Jin SM, et al. 2023. Nat Nanotechnol. :. PubMed
  29. Chen L, et al. 2023. Bioeng Transl Med. 8:e10377. PubMed
  30. Stravokefalou V, et al. 2023. Front Immunol. 13:1014802. PubMed
  31. Zhao Y, et al. 2023. Sci Adv. 9:eabo1360. PubMed
  32. Liu X, et al. 2022. Pain. 163:508. PubMed
  33. González H, et al. 2022. Cell. 185:729. PubMed
  34. Mecklenburg J, et al. 2022. Brain Behav Immun. 101:246. PubMed
  35. Na E, et al. 2022. Am J Physiol Lung Cell Mol Physiol. 322:L550. PubMed
  36. Ma Y, et al. 2022. Am J Physiol Heart Circ Physiol. 322:H622. PubMed
  37. Ajay AK, et al. 2022. Cell Rep. 38:110473. PubMed
  38. Mise Y, et al. 2022. Carcinogenesis. 43:647. PubMed
  39. Pfeifhofer-Obermair C, et al. 2022. Bio Protoc. 12:e4378. PubMed
  40. Hanuscheck N, et al. 2022. J Exp Med. 219:. PubMed
  41. Klawitter M, et al. 2022. Int J Mol Sci. 23:. PubMed
  42. Zheng Y, et al. 2022. Proc Natl Acad Sci U S A. 119:e2121077119. PubMed
  43. Bowley TY, et al. 2022. Cancer Res Commun. 2:1436. PubMed
  44. Chen Y, et al. 2022. Am J Cancer Res. 12:5286. PubMed
  45. Zhang Y, et al. 2023. Invest Ophthalmol Vis Sci. 64:1. PubMed
  46. Sparbier CE, et al. 2023. Nat Cell Biol. 25:258. PubMed
  47. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  48. Li M, et al. 2023. Front Immunol. 14:1087923. PubMed
  49. Chen H, et al. 2023. Nat Commun. 14:941. PubMed
  50. Ferriz M, et al. 2023. STAR Protoc. 4:102079. PubMed
  51. Volkova MV, et al. 2023. Int J Mol Sci. 24:. PubMed
  52. Solier S, et al. 2023. Int J Mol Sci. 24:. PubMed
  53. Li L, et al. 2023. iScience. 26:106095. PubMed
  54. Cheong LY, et al. 2023. Nat Commun. 14:1213. PubMed
  55. Xu H, et al. 2023. Acta Pharm Sin B. 13:678. PubMed
  56. Kozlovski S, et al. 2023. Front Immunol. 13:1041552. PubMed
  57. Rege SV, et al. 2023. Commun Biol. 6:292. PubMed
  58. Wang Y, et al. 2023. J Nanobiotechnology. 21:109. PubMed
  59. Zhang X, et al. 2023. Front Immunol. 14:1116749. PubMed
  60. Kim BH, et al. 2023. Sci Rep. 13:6577. PubMed
  61. Li T, et al. 2023. Nat Commun. 14:2498. PubMed
  62. Kase N, et al. 2023. Front Cell Dev Biol. 11:1022081. PubMed
  63. Huang T, et al. 2023. Cell Death Dis. 14:354. PubMed
  64. Guo X, et al. 2023. Mol Immunol. 160:32. PubMed
  65. Wang X, et al. 2023. Nature. 618:808. PubMed
  66. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  67. J Gautam, X Zhang, Y Yao 2016. Sci Rep. 6:36450. PubMed
  68. Hulsebus HJ, et al. 2022. Front Immunol. 13:884719. PubMed
  69. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  70. El-Hindi K, et al. 2022. Int J Mol Sci. 23:. PubMed
  71. Qi Z, et al. 2022. Nat Commun. 13:182. PubMed
  72. Ma J, et al. 2020. Adv Sci (Weinh). 7:2000609. PubMed
  73. Sharma GP, et al. 2021. PLoS One. 16:e0259042. PubMed
  74. Huang Z et al. 2017. Cell metabolism. 26(3):493-508 . PubMed
  75. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  76. Hofmann I, et al. 2022. J Pharmacol Exp Ther. Online ahead of print. PubMed
  77. Prado C, et al. 2021. J Neuroinflammation. 18:292. PubMed
  78. Wang M, et al. 2022. Theranostics. 12:4513. PubMed
  79. Adachi Y, et al. 2022. Nat Commun. 13:5117. PubMed
  80. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  81. Tcheng M, et al. 2021. Blood. 137:3518. PubMed
  82. Zhu H, et al. 2018. Elife. 7:. PubMed
  83. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  84. Sepe JJ, et al. 2022. JACC Basic Transl Sci. 7:915. PubMed
  85. Abdala-Valencia H, et al. 2014. Am J Physiol Lung Cell Mol Physiol. 307:482. PubMed
  86. Shao Y, et al. 2019. Diabetes. 68:2131. PubMed
  87. Lee AK, et al. 2020. Radiat Res. 193:305. PubMed
  88. Pan D, et al. 2022. Cancer Res. 82:2748. PubMed
  89. Rao E, et al. 2021. Sci Immunol. 6:. PubMed
  90. Saito S, et al. 2020. Nutrients. 12:. PubMed
  91. Liu X, et al. 2020. Nature. . PubMed
  92. Liang W, et al. 2020. Nat Commun. 4.563888889. PubMed
  93. Choi H et al. 2019. Cell Rep. 27(3):806-819 . PubMed
  94. Agelidis A, et al. 2019. Front Immunol. 10:500. PubMed
  95. Neumann AM et al. 2017. PloS one. 12(11):e0187330 . PubMed
  96. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  97. Ohigashi I, et al. 2020. Cell Reports. 29(9):2901-2916.e6.. PubMed
  98. Ihara S, et al. 2022. PLoS Negl Trop Dis. 16:e0010323. PubMed
  99. Talma N, et al. 2021. Aging Cell. 20:e13450. PubMed
  100. Zhao G, et al. 2020. Sci Adv. 6:00. PubMed
  101. Evren E, et al. 2020. Immunity. 54(2):259-275.e7. PubMed
  102. Wosczyna MN, et al. 2021. Cell Stem Cell. 28(7):1323-1334.e8. PubMed
  103. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  104. Wang X, et al. 2021. Front Cell Dev Biol. 632805:9. PubMed
  105. Zhang Q, et al. 2019. PLoS Biol. 17:e3000330. PubMed
  106. Zhang C, et al. 2020. Cell Metabolism. 31(1):148-161.e5.. PubMed
  107. Lu Y, et al. 2020. Cell. 180(6):1081-1097. PubMed
  108. Francian A, et al. 2021. J Drug Target. 29:754. PubMed
  109. Johansen AZ, et al. 2022. Pharmaceutics. 14:. PubMed
  110. Rolfes S, et al. 2020. Neurobiol Dis. 144:105024. PubMed
  111. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  112. Han C, et al. 2021. Cell Reports. 34(6):108706. PubMed
  113. Meixiong J et al. 2019. Immunity. 50(5):1163-1171 . PubMed
  114. Xiao X, et al. 2019. Cell Discov. 5:2. PubMed
  115. Dai B, et al. 2022. Theranostics. 12:7603. PubMed
  116. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  117. Dane EL, et al. 2022. Nat Mater. 21:710. PubMed
  118. Yao L, et al. 2021. J Bone Miner Res. 36:1159. PubMed
  119. Koujah L, et al. 2021. Ocul Surf. 21:238. PubMed
  120. Kumari A, et al. 2022. Sci Rep. 12:15273. PubMed
  121. Li P, et al. 2021. Nat Immunol. 22:1107. PubMed
  122. Zhang X, et al. 2022. Cells. 11:. PubMed
  123. Kucinski I, et al. 2020. EMBO J. :e104983. PubMed
  124. Müller A, et al. 2020. J Clin Invest. 5765:130. PubMed
  125. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  126. Zhang W, et al. 2021. Cell Prolif. 54:e13058. PubMed
  127. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  128. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  129. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  130. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  131. Feng Y, et al. 2018. Kidney Dis (Basel). 4:95. PubMed
  132. Wosczyna MN et al. 2019. Cell Rep. 27(7):2029-2035 . PubMed
  133. Plein A, et al. 2018. Nature. 562:223. PubMed
  134. Kobayashi S, et al. 2019. J Immunol. 203:1447. PubMed
  135. Green DP, et al. 2019. Neuron. 101:412. PubMed
  136. Zein HS, et al. 2022. Sci Rep. 12:4834. PubMed
  137. Luo W, et al. 2022. Front Immunol. 13:816761. PubMed
  138. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  139. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  140. Barman PK, et al. 2019. J Immunol. 202:2720. PubMed
  141. Lim D, et al. 2018. Front Physiol. 9:47. PubMed
  142. Cervera–Carrascon V, et al. 2020. Oncoimmunology. 9:1761229. PubMed
  143. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  144. Gañán-Gómez I, et al. 2022. Nat Med. . PubMed
  145. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  146. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  147. Li J, et al. 2020. Elife. 9:00. PubMed
  148. Rosa JM, et al. 2021. British Journal of Pharmacology. . PubMed
  149. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  150. Morimoto A, et al. 2021. Nat Commun. 12:2136. PubMed
  151. Poillet-Perez L, et al. 2020. Nat Cancer. 1:923. PubMed
  152. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  153. Wang ECE, et al. 2019. Cell Stem Cell. 24:654. PubMed
  154. Zhang K, et al. 2014. PLoS Pathog. 10:1004385. PubMed
  155. Mencarelli A, et al. 2016. Sci Rep. 6:30802. PubMed
  156. Lu X, et al. 2016. Nat Commun. 7: 12719. PubMed
  157. Goldfarb Y, et al. 2021. J Exp Med. 218:. PubMed
  158. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  159. Ye P, et al. 2022. Front Cardiovasc Med. 8:810477. PubMed
  160. Brigas HC, et al. 2021. Cell Reports. 36(9):109574. PubMed
  161. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  162. Nguyen PT, et al. 2020. Cell. 182(2):388-403.e15. PubMed
  163. Liu CY, et al. 2020. Cell Rep. 33:108275. PubMed
  164. Wan X, et al. 2018. Nature. 560:107. PubMed
  165. Al–Zaher AA, et al. 2018. Mol Ther Oncolytics. 0.376388889. PubMed
  166. Hepler C et al. 2018. eLife. 7 pii: e39636. PubMed
  167. Burr ML, et al. 2019. Cancer Cell. 36:385. PubMed
  168. Wang F, et al. 2019. MAbs. 12:1685350. PubMed
  169. Ji DX, et al. 2019. Nat Microbiol. 1.644444444. PubMed
  170. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  171. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  172. Sefik E, et al. 2021. Nat Biotechnol. . PubMed
  173. Watanabe Y, et al. 2020. J Biol Chem. 295:17632. PubMed
  174. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  175. Ruan C, et al. 2020. Brain Behav Immun. 83:180. PubMed
  176. Cai Y, et al. 2019. Cell Rep. 27:3034. PubMed
  177. Crowell PD et al. 2019. Cell Rep. 28(6):1499-1510 . PubMed
  178. Maetzig T, et al. 2017. Mol Ther. 25:606. PubMed
  179. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  180. Pundir P, et al. 2020. Cell Host & Microbe. 26(1):114-122. PubMed
  181. Milner MT, et al. 2022. STAR Protoc. 3:101295. PubMed
  182. Zhang X, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  183. Xiao L, et al. 2021. Clin Cancer Res. 27:4338. PubMed
  184. Kotas ME, et al. 2022. JCI Insight. :. PubMed
  185. Rashid MH, et al. 2021. Oncol Rep. 45:1171. PubMed
  186. Jiang Y, et al. 2021. Cell Death Differ. 28:3009. PubMed
  187. Agelidis A, et al. 2021. JCI Insight. 6: . PubMed
  188. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  189. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  190. Gastelum‐Aviña P et al. 2016. Journal of immunological methods. 438:42-50 . PubMed
  191. Zhou J, et al. 2019. Nat Commun. 10:2427. PubMed
  192. Yu X, et al. 2019. Nat Commun. 10:574. PubMed
  193. Su S et al. 2018. Cell. 175(2):442-457 . PubMed
  194. Galle-Treger L, et al. 2016. Nat Commun. 7:13202. PubMed
  195. Minhas PS, et al. 2021. Nature. 590:122. PubMed
  196. Zhang X, et al. 2021. Mol Cancer Res. 19:1076. PubMed
  197. Liu S, et al. 2022. J Neuroinflammation. 19:35. PubMed
  198. Xiao Y, et al. 2022. Nat Commun. 13:758. PubMed
  199. Ali S, et al. 2021. PLoS One. 16:e0246646. PubMed
  200. Yang Z, et al. 2021. Nat Commun. 12:4852. PubMed
  201. Long JT, et al. 2022. Elife. 11:. PubMed
  202. Bravo-Caparrós I, et al. 2020. FASEB J. 34:5951. PubMed
  203. Zhang P, et al. 2022. Nat Commun. 13:1588. PubMed
  204. Jiang Q, et al. 2020. JCI Insight. 5:00. PubMed
  205. Hasegawa T, et al. 2020. Sci Rep. 10:13480. PubMed
  206. Johnson DC, et al. 2020. Cell Death Dis. 0.894444444. PubMed
  207. Li CM, et al. 2020. Cell Reports. 33(13):108566. PubMed
  208. Zhang L, et al. 2021. iScience. 24(9):102942. PubMed
  209. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  210. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  211. Sarvi S et al. 2018. Cell chemical biology. 25(12):1456-1469 . PubMed
  212. Sirvinskas D, et al. 2022. iScience. 25:104202. PubMed
  213. Ito K, et al. 2014. Proc Natl Acad Sci U S A. 111:3080. PubMed
  214. Saunders L, et al. 2015. Sci Transl Med. 7: 302ra136. PubMed
  215. Qi F, et al. 2019. Front Microbiol. 2.140277778. PubMed
  216. Yu JM, et al. 2019. Nat Commun. 4.388888889. PubMed
  217. Hou Y, et al. 2021. Sci Transl Med. 13:. PubMed
  218. Xu G, et al. 2022. Front Pharmacol. 13:896601. PubMed
  219. Zhou J, et al. 2022. Int J Oncol. 61: . PubMed
  220. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  221. Song J, et al. 2021. Am J Physiol Heart Circ Physiol. 320:H323. PubMed
  222. Zeis P, et al. 2020. Immunity. 53:775. PubMed
  223. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  224. Kim H, et al. 2020. Biomed Rep. 0.589583333. PubMed
  225. Li Z, et al. 2022. Nat Commun. 13:6321. PubMed
  226. Ferrer-Font L, et al. 2020. Elife. 9:. PubMed
  227. Sakai H, et al. 2022. iScience. 25:103928. PubMed
  228. Walker MT, et al. 2021. Front. Allergy. 2:. PubMed
  229. Kataru RP, et al. 2022. Front Aging. 3:864860. PubMed
  230. Pan Y, et al. 2021. Br J Pharmacol. 178:4907. PubMed
  231. Zheng B, et al. 2021. Bioact Mater. 6:3879. PubMed
  232. Ovadya Y, et al. 2018. Nat Commun. 9:5435. PubMed
  233. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  234. Chen M, et al. 2019. Cell Stem Cell. 25:501. PubMed
  235. Hameed H, et al. 2022. Int J Mol Sci. 23:. PubMed
  236. Ding R, et al. 2022. J Neuroinflammation. 19:137. PubMed
  237. Liu R, et al. 2020. Eur J Vasc Endovasc Surg. 60:254. PubMed
  238. Fan ZP, et al. 2021. Front Immunol. 12:743354. PubMed
  239. Okada R, et al. 2021. EBioMedicine. 67:103345. PubMed
  240. Sema Kurtulus et al. 2018. Immunity. 50(1):181-194 . PubMed
  241. Liu L et al. 2018. Cell stem cell. 23(4):544-556 . PubMed
  242. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  243. Chao Y, et al. 2020. Sci Adv. 6:eaaz4204. PubMed
  244. Kataru RP, et al. 2019. Cancer Immunol Res. 7:1345. PubMed
  245. Krivtsov AV, et al. 2020. Cancer Cell. 36(6):660-673.e11.. PubMed
  246. Hu X, et al. 2020. Neoplasia. 1.290972222. PubMed
  247. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  248. Ruan Y, et al. 2022. Exp Ther Med. 23:47. PubMed
  249. Wang R, et al. 2022. J Immunother Cancer. 10:. PubMed
  250. Liao X, et al. 2022. JCI Insight. 7:. PubMed
  251. Kelley WJ, et al. 2022. JCI Insight. 7: . PubMed
  252. Simoes Eugénio M, et al. 2020. Cancers (Basel). 12:00. PubMed
  253. Chen L, et al. 2021. Theranostics. 11:6668. PubMed
  254. Sugita Y, et al. 2021. Oncol Rep. 45:. PubMed
  255. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  256. Hao T, et al. 2019. Nat Commun. 10:3665. PubMed
  257. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  258. Cerina M, et al. 2017. Brain Behav Immun. 59:103-117. PubMed
  259. Tr änkner D, et al. 2019. Cell Rep. 29:791. PubMed
  260. Lee C, et al. 2020. Front Immunol. 11:77. PubMed
  261. Eckert EC, et al. 2020. Mol Ther Oncolytics. 0.710416667. PubMed
  262. Zhou Y, et al. 2022. Theranostics. 12:5488. PubMed
  263. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  264. El-Obeid A, et al. 2021. Exp Ther Med. 22:1081. PubMed
  265. Sharma R, et al. 2021. J Neuroinflammation. 72:18. PubMed
  266. Watanabe Y, et al. 2020. J Biol Chem. . PubMed
  267. Sheng J, et al. 2021. eLife. 10:00. PubMed
  268. Poillet–Perez L, et al. 2018. Nature. 563:569. PubMed
  269. Padhye A, et al. 2019. Sci Rep. 9:4819. PubMed
  270. Shao Y, et al. 2019. Stem Cells. 37:1331. PubMed
  271. Krotova K, et al. 2019. Mol Ther Oncolytics. 15:166. PubMed
  272. Gupta R, et al. 2020. Cell Stem Cell. 26:527. PubMed
  273. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  274. Li M, et al. 2020. Nat Commun. 4051:11. PubMed
  275. Le TM et al. 2018. Journal of neurochemistry. 145(2):139-153 . PubMed
  276. Lee EKS, et al. 2018. Cell Host Microbe. 23:121. PubMed
  277. Ma Y, et al. 2020. Front Immunol. 11:586685. PubMed
  278. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  279. Guarnerio J, et al. 2018. Nat Commun. 9:66. PubMed
  280. Wolf Y, et al. 2019. Cell. 179:219. PubMed
  281. Wang H, et al. 2022. J Cancer. 13:2126. PubMed
  282. Zhang SJ, et al. 2021. Adv Sci (Weinh). 8:2003410. PubMed
  283. Zhang L, et al. 2021. Mol Ther. 29:744. PubMed
  284. Andreata F, et al. 2021. STAR Protoc. 2:100831. PubMed
  285. Ichinose M, et al. 2021. Sci Rep. 7200:11. PubMed
  286. Zhang B, et al. 2021. Front Neurol. 607370:12. PubMed
  287. Dingler FA, et al. 2020. Mol Cell. . PubMed
  288. Wan Y, et al. 2020. Cell Rep. 33:108346. PubMed
  289. Badgujar DC, et al. 2020. PLoS Pathog. 16:e1009016. PubMed
  290. Li CY, et al. 2022. Int J Mol Sci. 23:. PubMed
  291. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  292. Xu X, et al. 2020. Chin Med. 15:33. PubMed
  293. Shakya S, et al. 2020. MethodsX. 7:101027. PubMed
  294. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  295. Kataru RP, et al. 2021. Sci Signal. 14:. PubMed
  296. Li Z, et al. 2022. Nat Commun. 13:1845. PubMed
  297. Li Y, et al. 2020. Nat Commun. 2.350694444. PubMed
  298. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  299. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  300. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  301. Johnson DC, et al. 2018. Nat Med. 24:1151. PubMed
  302. Sefik E, et al. 2022. Nature. 606:585. PubMed
  303. Leinroth AP, et al. 2022. Cell Rep. 39:110785. PubMed
  304. Doughty D, et al. 2022. Exp Biol Med (Maywood). 247:1433. PubMed
  305. Du M, et al. 2022. Cancer Sci. 113:2974. PubMed
  306. Grégoire C, et al. 2022. Immunity. 55:1216. PubMed
  307. Tao X, et al. 2022. EMBO J. 41:e110439. PubMed
  308. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  309. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  310. Hindy G, et al. 2022. J Clin Invest. 132: . PubMed
  311. Roy IM, et al. 2022. iScience. 25:105171. PubMed
  312. Mendivil-Perez M, et al. 2022. Med Oncol. 40:15. PubMed
  313. Chen X, et al. 2022. J Extracell Vesicles. 11:e12279. PubMed
  314. Zheng Z, et al. 2022. Cells. 11: . PubMed
  315. Voit RA, et al. 2023. Nat Immunol. 24:69. PubMed
  316. Varshney R, et al. 2023. iScience. 26:105750. PubMed
  317. Cheng P, et al. 2023. Pharmacol Res. 188:106643. PubMed
  318. Jin SM, et al. 2023. Nat Nanotechnol. :. PubMed
  319. Chen L, et al. 2023. Bioeng Transl Med. 8:e10377. PubMed
  320. Stravokefalou V, et al. 2023. Front Immunol. 13:1014802. PubMed
  321. Zhao Y, et al. 2023. Sci Adv. 9:eabo1360. PubMed
  322. Liu X, et al. 2022. Pain. 163:508. PubMed
  323. González H, et al. 2022. Cell. 185:729. PubMed
  324. Mecklenburg J, et al. 2022. Brain Behav Immun. 101:246. PubMed
  325. Na E, et al. 2022. Am J Physiol Lung Cell Mol Physiol. 322:L550. PubMed
  326. Ma Y, et al. 2022. Am J Physiol Heart Circ Physiol. 322:H622. PubMed
  327. Ajay AK, et al. 2022. Cell Rep. 38:110473. PubMed
  328. Mise Y, et al. 2022. Carcinogenesis. 43:647. PubMed
  329. Pfeifhofer-Obermair C, et al. 2022. Bio Protoc. 12:e4378. PubMed
  330. Hanuscheck N, et al. 2022. J Exp Med. 219:. PubMed
  331. Klawitter M, et al. 2022. Int J Mol Sci. 23:. PubMed
  332. Zheng Y, et al. 2022. Proc Natl Acad Sci U S A. 119:e2121077119. PubMed
  333. Bowley TY, et al. 2022. Cancer Res Commun. 2:1436. PubMed
  334. Chen Y, et al. 2022. Am J Cancer Res. 12:5286. PubMed
  335. Zhang Y, et al. 2023. Invest Ophthalmol Vis Sci. 64:1. PubMed
  336. Sparbier CE, et al. 2023. Nat Cell Biol. 25:258. PubMed
  337. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  338. Li M, et al. 2023. Front Immunol. 14:1087923. PubMed
  339. Chen H, et al. 2023. Nat Commun. 14:941. PubMed
  340. Ferriz M, et al. 2023. STAR Protoc. 4:102079. PubMed
  341. Volkova MV, et al. 2023. Int J Mol Sci. 24:. PubMed
  342. Solier S, et al. 2023. Int J Mol Sci. 24:. PubMed
  343. Li L, et al. 2023. iScience. 26:106095. PubMed
  344. Cheong LY, et al. 2023. Nat Commun. 14:1213. PubMed
  345. Xu H, et al. 2023. Acta Pharm Sin B. 13:678. PubMed
  346. Kozlovski S, et al. 2023. Front Immunol. 13:1041552. PubMed
  347. Rege SV, et al. 2023. Commun Biol. 6:292. PubMed
  348. Wang Y, et al. 2023. J Nanobiotechnology. 21:109. PubMed
  349. Zhang X, et al. 2023. Front Immunol. 14:1116749. PubMed
  350. Kim BH, et al. 2023. Sci Rep. 13:6577. PubMed
  351. Li T, et al. 2023. Nat Commun. 14:2498. PubMed
  352. Kase N, et al. 2023. Front Cell Dev Biol. 11:1022081. PubMed
  353. Huang T, et al. 2023. Cell Death Dis. 14:354. PubMed
  354. Guo X, et al. 2023. Mol Immunol. 160:32. PubMed
  355. Wang X, et al. 2023. Nature. 618:808. PubMed
  356. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  357. J Gautam, X Zhang, Y Yao 2016. Sci Rep. 6:36450. PubMed
  358. Hulsebus HJ, et al. 2022. Front Immunol. 13:884719. PubMed
  359. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  360. El-Hindi K, et al. 2022. Int J Mol Sci. 23:. PubMed
  361. Qi Z, et al. 2022. Nat Commun. 13:182. PubMed
  362. Ma J, et al. 2020. Adv Sci (Weinh). 7:2000609. PubMed
  363. Sharma GP, et al. 2021. PLoS One. 16:e0259042. PubMed
  364. Huang Z et al. 2017. Cell metabolism. 26(3):493-508 . PubMed
  365. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  366. Hofmann I, et al. 2022. J Pharmacol Exp Ther. Online ahead of print. PubMed
  367. Prado C, et al. 2021. J Neuroinflammation. 18:292. PubMed
  368. Wang M, et al. 2022. Theranostics. 12:4513. PubMed
  369. Adachi Y, et al. 2022. Nat Commun. 13:5117. PubMed
  370. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  371. Tcheng M, et al. 2021. Blood. 137:3518. PubMed
  372. Zhu H, et al. 2018. Elife. 7:. PubMed
  373. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  374. Sepe JJ, et al. 2022. JACC Basic Transl Sci. 7:915. PubMed
  375. Abdala-Valencia H, et al. 2014. Am J Physiol Lung Cell Mol Physiol. 307:482. PubMed
  376. Shao Y, et al. 2019. Diabetes. 68:2131. PubMed
  377. Lee AK, et al. 2020. Radiat Res. 193:305. PubMed
  378. Pan D, et al. 2022. Cancer Res. 82:2748. PubMed
  379. Rao E, et al. 2021. Sci Immunol. 6:. PubMed
  380. Saito S, et al. 2020. Nutrients. 12:. PubMed
  381. Liu X, et al. 2020. Nature. . PubMed
  382. Liang W, et al. 2020. Nat Commun. 4.563888889. PubMed
  383. Choi H et al. 2019. Cell Rep. 27(3):806-819 . PubMed
  384. Agelidis A, et al. 2019. Front Immunol. 10:500. PubMed
  385. Neumann AM et al. 2017. PloS one. 12(11):e0187330 . PubMed
  386. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  387. Ohigashi I, et al. 2020. Cell Reports. 29(9):2901-2916.e6.. PubMed
  388. Ihara S, et al. 2022. PLoS Negl Trop Dis. 16:e0010323. PubMed
  389. Talma N, et al. 2021. Aging Cell. 20:e13450. PubMed
  390. Zhao G, et al. 2020. Sci Adv. 6:00. PubMed
  391. Evren E, et al. 2020. Immunity. 54(2):259-275.e7. PubMed
  392. Wosczyna MN, et al. 2021. Cell Stem Cell. 28(7):1323-1334.e8. PubMed
  393. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  394. Wang X, et al. 2021. Front Cell Dev Biol. 632805:9. PubMed
  395. Zhang Q, et al. 2019. PLoS Biol. 17:e3000330. PubMed
  396. Zhang C, et al. 2020. Cell Metabolism. 31(1):148-161.e5.. PubMed
  397. Lu Y, et al. 2020. Cell. 180(6):1081-1097. PubMed
  398. Francian A, et al. 2021. J Drug Target. 29:754. PubMed
  399. Johansen AZ, et al. 2022. Pharmaceutics. 14:. PubMed
  400. Rolfes S, et al. 2020. Neurobiol Dis. 144:105024. PubMed
  401. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  402. Han C, et al. 2021. Cell Reports. 34(6):108706. PubMed
  403. Meixiong J et al. 2019. Immunity. 50(5):1163-1171 . PubMed
  404. Xiao X, et al. 2019. Cell Discov. 5:2. PubMed
  405. Dai B, et al. 2022. Theranostics. 12:7603. PubMed
  406. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  407. Dane EL, et al. 2022. Nat Mater. 21:710. PubMed
  408. Yao L, et al. 2021. J Bone Miner Res. 36:1159. PubMed
  409. Koujah L, et al. 2021. Ocul Surf. 21:238. PubMed
  410. Kumari A, et al. 2022. Sci Rep. 12:15273. PubMed
  411. Li P, et al. 2021. Nat Immunol. 22:1107. PubMed
  412. Zhang X, et al. 2022. Cells. 11:. PubMed
  413. Kucinski I, et al. 2020. EMBO J. :e104983. PubMed
  414. Müller A, et al. 2020. J Clin Invest. 5765:130. PubMed
  415. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  416. Zhang W, et al. 2021. Cell Prolif. 54:e13058. PubMed
  417. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  418. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  419. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  420. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  421. Feng Y, et al. 2018. Kidney Dis (Basel). 4:95. PubMed
  422. Wosczyna MN et al. 2019. Cell Rep. 27(7):2029-2035 . PubMed
  423. Plein A, et al. 2018. Nature. 562:223. PubMed
  424. Kobayashi S, et al. 2019. J Immunol. 203:1447. PubMed
  425. Green DP, et al. 2019. Neuron. 101:412. PubMed
  426. Zein HS, et al. 2022. Sci Rep. 12:4834. PubMed
  427. Luo W, et al. 2022. Front Immunol. 13:816761. PubMed
  428. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  429. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  430. Barman PK, et al. 2019. J Immunol. 202:2720. PubMed
  431. Lim D, et al. 2018. Front Physiol. 9:47. PubMed
  432. Cervera–Carrascon V, et al. 2020. Oncoimmunology. 9:1761229. PubMed
  433. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  434. Gañán-Gómez I, et al. 2022. Nat Med. . PubMed
  435. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  436. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  437. Li J, et al. 2020. Elife. 9:00. PubMed
  438. Rosa JM, et al. 2021. British Journal of Pharmacology. . PubMed
  439. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  440. Morimoto A, et al. 2021. Nat Commun. 12:2136. PubMed
  441. Poillet-Perez L, et al. 2020. Nat Cancer. 1:923. PubMed
  442. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  443. Wang ECE, et al. 2019. Cell Stem Cell. 24:654. PubMed
  444. Zhang K, et al. 2014. PLoS Pathog. 10:1004385. PubMed
  445. Mencarelli A, et al. 2016. Sci Rep. 6:30802. PubMed
  446. Lu X, et al. 2016. Nat Commun. 7: 12719. PubMed
  447. Goldfarb Y, et al. 2021. J Exp Med. 218:. PubMed
  448. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  449. Ye P, et al. 2022. Front Cardiovasc Med. 8:810477. PubMed
  450. Brigas HC, et al. 2021. Cell Reports. 36(9):109574. PubMed
  451. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  452. Nguyen PT, et al. 2020. Cell. 182(2):388-403.e15. PubMed
  453. Liu CY, et al. 2020. Cell Rep. 33:108275. PubMed
  454. Wan X, et al. 2018. Nature. 560:107. PubMed
  455. Al–Zaher AA, et al. 2018. Mol Ther Oncolytics. 0.376388889. PubMed
  456. Hepler C et al. 2018. eLife. 7 pii: e39636. PubMed
  457. Burr ML, et al. 2019. Cancer Cell. 36:385. PubMed
  458. Wang F, et al. 2019. MAbs. 12:1685350. PubMed
  459. Ji DX, et al. 2019. Nat Microbiol. 1.644444444. PubMed
  460. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  461. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  462. Sefik E, et al. 2021. Nat Biotechnol. . PubMed
  463. Watanabe Y, et al. 2020. J Biol Chem. 295:17632. PubMed
  464. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  465. Ruan C, et al. 2020. Brain Behav Immun. 83:180. PubMed
  466. Cai Y, et al. 2019. Cell Rep. 27:3034. PubMed
  467. Crowell PD et al. 2019. Cell Rep. 28(6):1499-1510 . PubMed
  468. Maetzig T, et al. 2017. Mol Ther. 25:606. PubMed
  469. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  470. Pundir P, et al. 2020. Cell Host & Microbe. 26(1):114-122. PubMed
  471. Milner MT, et al. 2022. STAR Protoc. 3:101295. PubMed
  472. Zhang X, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  473. Xiao L, et al. 2021. Clin Cancer Res. 27:4338. PubMed
  474. Kotas ME, et al. 2022. JCI Insight. :. PubMed
  475. Rashid MH, et al. 2021. Oncol Rep. 45:1171. PubMed
  476. Jiang Y, et al. 2021. Cell Death Differ. 28:3009. PubMed
  477. Agelidis A, et al. 2021. JCI Insight. 6: . PubMed
  478. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  479. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  480. Gastelum‐Aviña P et al. 2016. Journal of immunological methods. 438:42-50 . PubMed
  481. Zhou J, et al. 2019. Nat Commun. 10:2427. PubMed
  482. Yu X, et al. 2019. Nat Commun. 10:574. PubMed
  483. Su S et al. 2018. Cell. 175(2):442-457 . PubMed
  484. Galle-Treger L, et al. 2016. Nat Commun. 7:13202. PubMed
  485. Minhas PS, et al. 2021. Nature. 590:122. PubMed
  486. Zhang X, et al. 2021. Mol Cancer Res. 19:1076. PubMed
  487. Liu S, et al. 2022. J Neuroinflammation. 19:35. PubMed
  488. Xiao Y, et al. 2022. Nat Commun. 13:758. PubMed
  489. Ali S, et al. 2021. PLoS One. 16:e0246646. PubMed
  490. Yang Z, et al. 2021. Nat Commun. 12:4852. PubMed
  491. Long JT, et al. 2022. Elife. 11:. PubMed
  492. Bravo-Caparrós I, et al. 2020. FASEB J. 34:5951. PubMed
  493. Zhang P, et al. 2022. Nat Commun. 13:1588. PubMed
  494. Jiang Q, et al. 2020. JCI Insight. 5:00. PubMed
  495. Hasegawa T, et al. 2020. Sci Rep. 10:13480. PubMed
  496. Johnson DC, et al. 2020. Cell Death Dis. 0.894444444. PubMed
  497. Li CM, et al. 2020. Cell Reports. 33(13):108566. PubMed
  498. Zhang L, et al. 2021. iScience. 24(9):102942. PubMed
  499. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  500. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  501. Sarvi S et al. 2018. Cell chemical biology. 25(12):1456-1469 . PubMed
  502. Sirvinskas D, et al. 2022. iScience. 25:104202. PubMed
  503. Ito K, et al. 2014. Proc Natl Acad Sci U S A. 111:3080. PubMed
  504. Saunders L, et al. 2015. Sci Transl Med. 7: 302ra136. PubMed
  505. Qi F, et al. 2019. Front Microbiol. 2.140277778. PubMed
  506. Yu JM, et al. 2019. Nat Commun. 4.388888889. PubMed
  507. Hou Y, et al. 2021. Sci Transl Med. 13:. PubMed
  508. Xu G, et al. 2022. Front Pharmacol. 13:896601. PubMed
  509. Zhou J, et al. 2022. Int J Oncol. 61: . PubMed
  510. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  511. Song J, et al. 2021. Am J Physiol Heart Circ Physiol. 320:H323. PubMed
  512. Zeis P, et al. 2020. Immunity. 53:775. PubMed
  513. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  514. Kim H, et al. 2020. Biomed Rep. 0.589583333. PubMed
  515. Li Z, et al. 2022. Nat Commun. 13:6321. PubMed
  516. Ferrer-Font L, et al. 2020. Elife. 9:. PubMed
  517. Sakai H, et al. 2022. iScience. 25:103928. PubMed
  518. Walker MT, et al. 2021. Front. Allergy. 2:. PubMed
  519. Kataru RP, et al. 2022. Front Aging. 3:864860. PubMed
  520. Pan Y, et al. 2021. Br J Pharmacol. 178:4907. PubMed
  521. Zheng B, et al. 2021. Bioact Mater. 6:3879. PubMed
  522. Ovadya Y, et al. 2018. Nat Commun. 9:5435. PubMed
  523. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  524. Chen M, et al. 2019. Cell Stem Cell. 25:501. PubMed
  525. Hameed H, et al. 2022. Int J Mol Sci. 23:. PubMed
  526. Ding R, et al. 2022. J Neuroinflammation. 19:137. PubMed
  527. Liu R, et al. 2020. Eur J Vasc Endovasc Surg. 60:254. PubMed
  528. Fan ZP, et al. 2021. Front Immunol. 12:743354. PubMed
  529. Okada R, et al. 2021. EBioMedicine. 67:103345. PubMed
  530. Sema Kurtulus et al. 2018. Immunity. 50(1):181-194 . PubMed
  531. Liu L et al. 2018. Cell stem cell. 23(4):544-556 . PubMed
  532. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  533. Chao Y, et al. 2020. Sci Adv. 6:eaaz4204. PubMed
  534. Kataru RP, et al. 2019. Cancer Immunol Res. 7:1345. PubMed
  535. Krivtsov AV, et al. 2020. Cancer Cell. 36(6):660-673.e11.. PubMed
  536. Hu X, et al. 2020. Neoplasia. 1.290972222. PubMed
  537. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  538. Ruan Y, et al. 2022. Exp Ther Med. 23:47. PubMed
  539. Wang R, et al. 2022. J Immunother Cancer. 10:. PubMed
  540. Liao X, et al. 2022. JCI Insight. 7:. PubMed
  541. Kelley WJ, et al. 2022. JCI Insight. 7: . PubMed
  542. Simoes Eugénio M, et al. 2020. Cancers (Basel). 12:00. PubMed
  543. Chen L, et al. 2021. Theranostics. 11:6668. PubMed
  544. Sugita Y, et al. 2021. Oncol Rep. 45:. PubMed
  545. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  546. Hao T, et al. 2019. Nat Commun. 10:3665. PubMed
  547. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  548. Cerina M, et al. 2017. Brain Behav Immun. 59:103-117. PubMed
  549. Tr änkner D, et al. 2019. Cell Rep. 29:791. PubMed
  550. Lee C, et al. 2020. Front Immunol. 11:77. PubMed
  551. Eckert EC, et al. 2020. Mol Ther Oncolytics. 0.710416667. PubMed
  552. Zhou Y, et al. 2022. Theranostics. 12:5488. PubMed
  553. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  554. El-Obeid A, et al. 2021. Exp Ther Med. 22:1081. PubMed
  555. Sharma R, et al. 2021. J Neuroinflammation. 72:18. PubMed
  556. Watanabe Y, et al. 2020. J Biol Chem. . PubMed
  557. Sheng J, et al. 2021. eLife. 10:00. PubMed
  558. Poillet–Perez L, et al. 2018. Nature. 563:569. PubMed
  559. Padhye A, et al. 2019. Sci Rep. 9:4819. PubMed
  560. Shao Y, et al. 2019. Stem Cells. 37:1331. PubMed
  561. Krotova K, et al. 2019. Mol Ther Oncolytics. 15:166. PubMed
  562. Gupta R, et al. 2020. Cell Stem Cell. 26:527. PubMed
  563. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  564. Li M, et al. 2020. Nat Commun. 4051:11. PubMed
  565. Le TM et al. 2018. Journal of neurochemistry. 145(2):139-153 . PubMed
  566. Lee EKS, et al. 2018. Cell Host Microbe. 23:121. PubMed
  567. Ma Y, et al. 2020. Front Immunol. 11:586685. PubMed
  568. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  569. Guarnerio J, et al. 2018. Nat Commun. 9:66. PubMed
  570. Wolf Y, et al. 2019. Cell. 179:219. PubMed
  571. Wang H, et al. 2022. J Cancer. 13:2126. PubMed
  572. Zhang SJ, et al. 2021. Adv Sci (Weinh). 8:2003410. PubMed
  573. Zhang L, et al. 2021. Mol Ther. 29:744. PubMed
  574. Andreata F, et al. 2021. STAR Protoc. 2:100831. PubMed
  575. Ichinose M, et al. 2021. Sci Rep. 7200:11. PubMed
  576. Zhang B, et al. 2021. Front Neurol. 607370:12. PubMed
  577. Dingler FA, et al. 2020. Mol Cell. . PubMed
  578. Wan Y, et al. 2020. Cell Rep. 33:108346. PubMed
  579. Badgujar DC, et al. 2020. PLoS Pathog. 16:e1009016. PubMed
  580. Li CY, et al. 2022. Int J Mol Sci. 23:. PubMed
RRID
AB_312972 (BioLegend Cat. No. 103107)
AB_312973 (BioLegend Cat. No. 103108)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
PE anti-mouse CD45 30-F11 FC
PE/Cyanine5 anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine7 anti-mouse CD45 30-F11 FC
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
APC anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark Blue™ 515 anti-mouse CD45 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
PE/Fire™ 810 anti-mouse CD45 30-F11 FC
Spark PLUS UV395™ anti-mouse CD45 30-F11 FC
Spark Red™ 718 anti-mouse CD45 30-F11 FC
Spark PLUS V475™ anti-mouse CD45 Antibody 30-F11 FC
Spark YG™ 581 anti-mouse CD45 (Flexi-Fluor™) 30-F11 FC
StarBright UltraViolet 740 anti-mouse CD45 30-F11 FC
Go To Top Version: 2    Revision Date: 05/14/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Pricing & Availability
Clone
30-F11 (See other available formats)
Regulatory Status
RUO
Other Names
T200, Ly-5, LCA
Isotype
Rat IgG2b, κ
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Product Citations
publications
30-f11
C57BL/6 splenocytes stained with 30-F11 FITC
  • 30-f11
    C57BL/6 splenocytes stained with 30-F11 FITC
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability Save
103107 50 µg DKK214
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103108 500 µg DKK624
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Description

CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from variable splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Mouse thymus or spleen
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Clone 30-F11 reacts with all isoforms and both CD45.1 and CD45.2 alloantigens of CD45.

Additional reported applications (for relevant formats) include: immunoprecipitation3, complement-dependent cytotoxicity1,5, immunohistochemistry (acetone-fixed frozen sections, zinc-fixed paraffin-embedded sections and formalin-fixed paraffin-embedded sections)4,6, Western blotting7, and spatial biology (IBEX)10,11. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 103163 and 103164).

Application References
  1. Podd BS, et al. 2006. J. Immunol. 176:6532. (FC, CMCD) PubMed
  2. Haynes NM, et al. 2007. J. Immunol. 179:5099. (FC)
  3. Ledbetter JA, et al. 1979. Immunol. Rev. 47:63. (IP)
  4. Simon DI, et al. 2000. J. Clin. Invest. 105:293. (IHC)
  5. Seaman WE. 1983. J. Immunol. 130:1713. (CMCD)
  6. Cornet A, et al. 2001. P. Natl. Acad. Sci. USA 98:13306. (IHC)
  7. Tsuboi S and Fukuda M. 1998. J. Biol. Chem. 273:30680. (WB) PubMed
  8. Liu F, et al. 2012. Blood. 119:3295. PubMed
  9. Pelletier AN, et al. 2012. J. Immunol. 188:5561. PubMed
  10. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  11. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  2. Xu X, et al. 2020. Chin Med. 15:33. PubMed
  3. Shakya S, et al. 2020. MethodsX. 7:101027. PubMed
  4. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  5. Kataru RP, et al. 2021. Sci Signal. 14:. PubMed
  6. Li Z, et al. 2022. Nat Commun. 13:1845. PubMed
  7. Li Y, et al. 2020. Nat Commun. 2.350694444. PubMed
  8. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  9. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  10. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  11. Johnson DC, et al. 2018. Nat Med. 24:1151. PubMed
  12. Sefik E, et al. 2022. Nature. 606:585. PubMed
  13. Leinroth AP, et al. 2022. Cell Rep. 39:110785. PubMed
  14. Doughty D, et al. 2022. Exp Biol Med (Maywood). 247:1433. PubMed
  15. Du M, et al. 2022. Cancer Sci. 113:2974. PubMed
  16. Grégoire C, et al. 2022. Immunity. 55:1216. PubMed
  17. Tao X, et al. 2022. EMBO J. 41:e110439. PubMed
  18. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  19. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  20. Hindy G, et al. 2022. J Clin Invest. 132: . PubMed
  21. Roy IM, et al. 2022. iScience. 25:105171. PubMed
  22. Mendivil-Perez M, et al. 2022. Med Oncol. 40:15. PubMed
  23. Chen X, et al. 2022. J Extracell Vesicles. 11:e12279. PubMed
  24. Zheng Z, et al. 2022. Cells. 11: . PubMed
  25. Voit RA, et al. 2023. Nat Immunol. 24:69. PubMed
  26. Varshney R, et al. 2023. iScience. 26:105750. PubMed
  27. Cheng P, et al. 2023. Pharmacol Res. 188:106643. PubMed
  28. Jin SM, et al. 2023. Nat Nanotechnol. :. PubMed
  29. Chen L, et al. 2023. Bioeng Transl Med. 8:e10377. PubMed
  30. Stravokefalou V, et al. 2023. Front Immunol. 13:1014802. PubMed
  31. Zhao Y, et al. 2023. Sci Adv. 9:eabo1360. PubMed
  32. Liu X, et al. 2022. Pain. 163:508. PubMed
  33. González H, et al. 2022. Cell. 185:729. PubMed
  34. Mecklenburg J, et al. 2022. Brain Behav Immun. 101:246. PubMed
  35. Na E, et al. 2022. Am J Physiol Lung Cell Mol Physiol. 322:L550. PubMed
  36. Ma Y, et al. 2022. Am J Physiol Heart Circ Physiol. 322:H622. PubMed
  37. Ajay AK, et al. 2022. Cell Rep. 38:110473. PubMed
  38. Mise Y, et al. 2022. Carcinogenesis. 43:647. PubMed
  39. Pfeifhofer-Obermair C, et al. 2022. Bio Protoc. 12:e4378. PubMed
  40. Hanuscheck N, et al. 2022. J Exp Med. 219:. PubMed
  41. Klawitter M, et al. 2022. Int J Mol Sci. 23:. PubMed
  42. Zheng Y, et al. 2022. Proc Natl Acad Sci U S A. 119:e2121077119. PubMed
  43. Bowley TY, et al. 2022. Cancer Res Commun. 2:1436. PubMed
  44. Chen Y, et al. 2022. Am J Cancer Res. 12:5286. PubMed
  45. Zhang Y, et al. 2023. Invest Ophthalmol Vis Sci. 64:1. PubMed
  46. Sparbier CE, et al. 2023. Nat Cell Biol. 25:258. PubMed
  47. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  48. Li M, et al. 2023. Front Immunol. 14:1087923. PubMed
  49. Chen H, et al. 2023. Nat Commun. 14:941. PubMed
  50. Ferriz M, et al. 2023. STAR Protoc. 4:102079. PubMed
  51. Volkova MV, et al. 2023. Int J Mol Sci. 24:. PubMed
  52. Solier S, et al. 2023. Int J Mol Sci. 24:. PubMed
  53. Li L, et al. 2023. iScience. 26:106095. PubMed
  54. Cheong LY, et al. 2023. Nat Commun. 14:1213. PubMed
  55. Xu H, et al. 2023. Acta Pharm Sin B. 13:678. PubMed
  56. Kozlovski S, et al. 2023. Front Immunol. 13:1041552. PubMed
  57. Rege SV, et al. 2023. Commun Biol. 6:292. PubMed
  58. Wang Y, et al. 2023. J Nanobiotechnology. 21:109. PubMed
  59. Zhang X, et al. 2023. Front Immunol. 14:1116749. PubMed
  60. Kim BH, et al. 2023. Sci Rep. 13:6577. PubMed
  61. Li T, et al. 2023. Nat Commun. 14:2498. PubMed
  62. Kase N, et al. 2023. Front Cell Dev Biol. 11:1022081. PubMed
  63. Huang T, et al. 2023. Cell Death Dis. 14:354. PubMed
  64. Guo X, et al. 2023. Mol Immunol. 160:32. PubMed
  65. Wang X, et al. 2023. Nature. 618:808. PubMed
  66. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  67. J Gautam, X Zhang, Y Yao 2016. Sci Rep. 6:36450. PubMed
  68. Hulsebus HJ, et al. 2022. Front Immunol. 13:884719. PubMed
  69. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  70. El-Hindi K, et al. 2022. Int J Mol Sci. 23:. PubMed
  71. Qi Z, et al. 2022. Nat Commun. 13:182. PubMed
  72. Ma J, et al. 2020. Adv Sci (Weinh). 7:2000609. PubMed
  73. Sharma GP, et al. 2021. PLoS One. 16:e0259042. PubMed
  74. Huang Z et al. 2017. Cell metabolism. 26(3):493-508 . PubMed
  75. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  76. Hofmann I, et al. 2022. J Pharmacol Exp Ther. Online ahead of print. PubMed
  77. Prado C, et al. 2021. J Neuroinflammation. 18:292. PubMed
  78. Wang M, et al. 2022. Theranostics. 12:4513. PubMed
  79. Adachi Y, et al. 2022. Nat Commun. 13:5117. PubMed
  80. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  81. Tcheng M, et al. 2021. Blood. 137:3518. PubMed
  82. Zhu H, et al. 2018. Elife. 7:. PubMed
  83. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  84. Sepe JJ, et al. 2022. JACC Basic Transl Sci. 7:915. PubMed
  85. Abdala-Valencia H, et al. 2014. Am J Physiol Lung Cell Mol Physiol. 307:482. PubMed
  86. Shao Y, et al. 2019. Diabetes. 68:2131. PubMed
  87. Lee AK, et al. 2020. Radiat Res. 193:305. PubMed
  88. Pan D, et al. 2022. Cancer Res. 82:2748. PubMed
  89. Rao E, et al. 2021. Sci Immunol. 6:. PubMed
  90. Saito S, et al. 2020. Nutrients. 12:. PubMed
  91. Liu X, et al. 2020. Nature. . PubMed
  92. Liang W, et al. 2020. Nat Commun. 4.563888889. PubMed
  93. Choi H et al. 2019. Cell Rep. 27(3):806-819 . PubMed
  94. Agelidis A, et al. 2019. Front Immunol. 10:500. PubMed
  95. Neumann AM et al. 2017. PloS one. 12(11):e0187330 . PubMed
  96. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  97. Ohigashi I, et al. 2020. Cell Reports. 29(9):2901-2916.e6.. PubMed
  98. Ihara S, et al. 2022. PLoS Negl Trop Dis. 16:e0010323. PubMed
  99. Talma N, et al. 2021. Aging Cell. 20:e13450. PubMed
  100. Zhao G, et al. 2020. Sci Adv. 6:00. PubMed
  101. Evren E, et al. 2020. Immunity. 54(2):259-275.e7. PubMed
  102. Wosczyna MN, et al. 2021. Cell Stem Cell. 28(7):1323-1334.e8. PubMed
  103. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  104. Wang X, et al. 2021. Front Cell Dev Biol. 632805:9. PubMed
  105. Zhang Q, et al. 2019. PLoS Biol. 17:e3000330. PubMed
  106. Zhang C, et al. 2020. Cell Metabolism. 31(1):148-161.e5.. PubMed
  107. Lu Y, et al. 2020. Cell. 180(6):1081-1097. PubMed
  108. Francian A, et al. 2021. J Drug Target. 29:754. PubMed
  109. Johansen AZ, et al. 2022. Pharmaceutics. 14:. PubMed
  110. Rolfes S, et al. 2020. Neurobiol Dis. 144:105024. PubMed
  111. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  112. Han C, et al. 2021. Cell Reports. 34(6):108706. PubMed
  113. Meixiong J et al. 2019. Immunity. 50(5):1163-1171 . PubMed
  114. Xiao X, et al. 2019. Cell Discov. 5:2. PubMed
  115. Dai B, et al. 2022. Theranostics. 12:7603. PubMed
  116. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  117. Dane EL, et al. 2022. Nat Mater. 21:710. PubMed
  118. Yao L, et al. 2021. J Bone Miner Res. 36:1159. PubMed
  119. Koujah L, et al. 2021. Ocul Surf. 21:238. PubMed
  120. Kumari A, et al. 2022. Sci Rep. 12:15273. PubMed
  121. Li P, et al. 2021. Nat Immunol. 22:1107. PubMed
  122. Zhang X, et al. 2022. Cells. 11:. PubMed
  123. Kucinski I, et al. 2020. EMBO J. :e104983. PubMed
  124. Müller A, et al. 2020. J Clin Invest. 5765:130. PubMed
  125. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  126. Zhang W, et al. 2021. Cell Prolif. 54:e13058. PubMed
  127. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  128. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  129. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  130. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  131. Feng Y, et al. 2018. Kidney Dis (Basel). 4:95. PubMed
  132. Wosczyna MN et al. 2019. Cell Rep. 27(7):2029-2035 . PubMed
  133. Plein A, et al. 2018. Nature. 562:223. PubMed
  134. Kobayashi S, et al. 2019. J Immunol. 203:1447. PubMed
  135. Green DP, et al. 2019. Neuron. 101:412. PubMed
  136. Zein HS, et al. 2022. Sci Rep. 12:4834. PubMed
  137. Luo W, et al. 2022. Front Immunol. 13:816761. PubMed
  138. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  139. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  140. Barman PK, et al. 2019. J Immunol. 202:2720. PubMed
  141. Lim D, et al. 2018. Front Physiol. 9:47. PubMed
  142. Cervera–Carrascon V, et al. 2020. Oncoimmunology. 9:1761229. PubMed
  143. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  144. Gañán-Gómez I, et al. 2022. Nat Med. . PubMed
  145. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  146. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  147. Li J, et al. 2020. Elife. 9:00. PubMed
  148. Rosa JM, et al. 2021. British Journal of Pharmacology. . PubMed
  149. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  150. Morimoto A, et al. 2021. Nat Commun. 12:2136. PubMed
  151. Poillet-Perez L, et al. 2020. Nat Cancer. 1:923. PubMed
  152. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  153. Wang ECE, et al. 2019. Cell Stem Cell. 24:654. PubMed
  154. Zhang K, et al. 2014. PLoS Pathog. 10:1004385. PubMed
  155. Mencarelli A, et al. 2016. Sci Rep. 6:30802. PubMed
  156. Lu X, et al. 2016. Nat Commun. 7: 12719. PubMed
  157. Goldfarb Y, et al. 2021. J Exp Med. 218:. PubMed
  158. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  159. Ye P, et al. 2022. Front Cardiovasc Med. 8:810477. PubMed
  160. Brigas HC, et al. 2021. Cell Reports. 36(9):109574. PubMed
  161. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  162. Nguyen PT, et al. 2020. Cell. 182(2):388-403.e15. PubMed
  163. Liu CY, et al. 2020. Cell Rep. 33:108275. PubMed
  164. Wan X, et al. 2018. Nature. 560:107. PubMed
  165. Al–Zaher AA, et al. 2018. Mol Ther Oncolytics. 0.376388889. PubMed
  166. Hepler C et al. 2018. eLife. 7 pii: e39636. PubMed
  167. Burr ML, et al. 2019. Cancer Cell. 36:385. PubMed
  168. Wang F, et al. 2019. MAbs. 12:1685350. PubMed
  169. Ji DX, et al. 2019. Nat Microbiol. 1.644444444. PubMed
  170. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  171. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  172. Sefik E, et al. 2021. Nat Biotechnol. . PubMed
  173. Watanabe Y, et al. 2020. J Biol Chem. 295:17632. PubMed
  174. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  175. Ruan C, et al. 2020. Brain Behav Immun. 83:180. PubMed
  176. Cai Y, et al. 2019. Cell Rep. 27:3034. PubMed
  177. Crowell PD et al. 2019. Cell Rep. 28(6):1499-1510 . PubMed
  178. Maetzig T, et al. 2017. Mol Ther. 25:606. PubMed
  179. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  180. Pundir P, et al. 2020. Cell Host & Microbe. 26(1):114-122. PubMed
  181. Milner MT, et al. 2022. STAR Protoc. 3:101295. PubMed
  182. Zhang X, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  183. Xiao L, et al. 2021. Clin Cancer Res. 27:4338. PubMed
  184. Kotas ME, et al. 2022. JCI Insight. :. PubMed
  185. Rashid MH, et al. 2021. Oncol Rep. 45:1171. PubMed
  186. Jiang Y, et al. 2021. Cell Death Differ. 28:3009. PubMed
  187. Agelidis A, et al. 2021. JCI Insight. 6: . PubMed
  188. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  189. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  190. Gastelum‐Aviña P et al. 2016. Journal of immunological methods. 438:42-50 . PubMed
  191. Zhou J, et al. 2019. Nat Commun. 10:2427. PubMed
  192. Yu X, et al. 2019. Nat Commun. 10:574. PubMed
  193. Su S et al. 2018. Cell. 175(2):442-457 . PubMed
  194. Galle-Treger L, et al. 2016. Nat Commun. 7:13202. PubMed
  195. Minhas PS, et al. 2021. Nature. 590:122. PubMed
  196. Zhang X, et al. 2021. Mol Cancer Res. 19:1076. PubMed
  197. Liu S, et al. 2022. J Neuroinflammation. 19:35. PubMed
  198. Xiao Y, et al. 2022. Nat Commun. 13:758. PubMed
  199. Ali S, et al. 2021. PLoS One. 16:e0246646. PubMed
  200. Yang Z, et al. 2021. Nat Commun. 12:4852. PubMed
  201. Long JT, et al. 2022. Elife. 11:. PubMed
  202. Bravo-Caparrós I, et al. 2020. FASEB J. 34:5951. PubMed
  203. Zhang P, et al. 2022. Nat Commun. 13:1588. PubMed
  204. Jiang Q, et al. 2020. JCI Insight. 5:00. PubMed
  205. Hasegawa T, et al. 2020. Sci Rep. 10:13480. PubMed
  206. Johnson DC, et al. 2020. Cell Death Dis. 0.894444444. PubMed
  207. Li CM, et al. 2020. Cell Reports. 33(13):108566. PubMed
  208. Zhang L, et al. 2021. iScience. 24(9):102942. PubMed
  209. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  210. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  211. Sarvi S et al. 2018. Cell chemical biology. 25(12):1456-1469 . PubMed
  212. Sirvinskas D, et al. 2022. iScience. 25:104202. PubMed
  213. Ito K, et al. 2014. Proc Natl Acad Sci U S A. 111:3080. PubMed
  214. Saunders L, et al. 2015. Sci Transl Med. 7: 302ra136. PubMed
  215. Qi F, et al. 2019. Front Microbiol. 2.140277778. PubMed
  216. Yu JM, et al. 2019. Nat Commun. 4.388888889. PubMed
  217. Hou Y, et al. 2021. Sci Transl Med. 13:. PubMed
  218. Xu G, et al. 2022. Front Pharmacol. 13:896601. PubMed
  219. Zhou J, et al. 2022. Int J Oncol. 61: . PubMed
  220. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  221. Song J, et al. 2021. Am J Physiol Heart Circ Physiol. 320:H323. PubMed
  222. Zeis P, et al. 2020. Immunity. 53:775. PubMed
  223. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  224. Kim H, et al. 2020. Biomed Rep. 0.589583333. PubMed
  225. Li Z, et al. 2022. Nat Commun. 13:6321. PubMed
  226. Ferrer-Font L, et al. 2020. Elife. 9:. PubMed
  227. Sakai H, et al. 2022. iScience. 25:103928. PubMed
  228. Walker MT, et al. 2021. Front. Allergy. 2:. PubMed
  229. Kataru RP, et al. 2022. Front Aging. 3:864860. PubMed
  230. Pan Y, et al. 2021. Br J Pharmacol. 178:4907. PubMed
  231. Zheng B, et al. 2021. Bioact Mater. 6:3879. PubMed
  232. Ovadya Y, et al. 2018. Nat Commun. 9:5435. PubMed
  233. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  234. Chen M, et al. 2019. Cell Stem Cell. 25:501. PubMed
  235. Hameed H, et al. 2022. Int J Mol Sci. 23:. PubMed
  236. Ding R, et al. 2022. J Neuroinflammation. 19:137. PubMed
  237. Liu R, et al. 2020. Eur J Vasc Endovasc Surg. 60:254. PubMed
  238. Fan ZP, et al. 2021. Front Immunol. 12:743354. PubMed
  239. Okada R, et al. 2021. EBioMedicine. 67:103345. PubMed
  240. Sema Kurtulus et al. 2018. Immunity. 50(1):181-194 . PubMed
  241. Liu L et al. 2018. Cell stem cell. 23(4):544-556 . PubMed
  242. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  243. Chao Y, et al. 2020. Sci Adv. 6:eaaz4204. PubMed
  244. Kataru RP, et al. 2019. Cancer Immunol Res. 7:1345. PubMed
  245. Krivtsov AV, et al. 2020. Cancer Cell. 36(6):660-673.e11.. PubMed
  246. Hu X, et al. 2020. Neoplasia. 1.290972222. PubMed
  247. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  248. Ruan Y, et al. 2022. Exp Ther Med. 23:47. PubMed
  249. Wang R, et al. 2022. J Immunother Cancer. 10:. PubMed
  250. Liao X, et al. 2022. JCI Insight. 7:. PubMed
  251. Kelley WJ, et al. 2022. JCI Insight. 7: . PubMed
  252. Simoes Eugénio M, et al. 2020. Cancers (Basel). 12:00. PubMed
  253. Chen L, et al. 2021. Theranostics. 11:6668. PubMed
  254. Sugita Y, et al. 2021. Oncol Rep. 45:. PubMed
  255. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  256. Hao T, et al. 2019. Nat Commun. 10:3665. PubMed
  257. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  258. Cerina M, et al. 2017. Brain Behav Immun. 59:103-117. PubMed
  259. Tr änkner D, et al. 2019. Cell Rep. 29:791. PubMed
  260. Lee C, et al. 2020. Front Immunol. 11:77. PubMed
  261. Eckert EC, et al. 2020. Mol Ther Oncolytics. 0.710416667. PubMed
  262. Zhou Y, et al. 2022. Theranostics. 12:5488. PubMed
  263. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  264. El-Obeid A, et al. 2021. Exp Ther Med. 22:1081. PubMed
  265. Sharma R, et al. 2021. J Neuroinflammation. 72:18. PubMed
  266. Watanabe Y, et al. 2020. J Biol Chem. . PubMed
  267. Sheng J, et al. 2021. eLife. 10:00. PubMed
  268. Poillet–Perez L, et al. 2018. Nature. 563:569. PubMed
  269. Padhye A, et al. 2019. Sci Rep. 9:4819. PubMed
  270. Shao Y, et al. 2019. Stem Cells. 37:1331. PubMed
  271. Krotova K, et al. 2019. Mol Ther Oncolytics. 15:166. PubMed
  272. Gupta R, et al. 2020. Cell Stem Cell. 26:527. PubMed
  273. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  274. Li M, et al. 2020. Nat Commun. 4051:11. PubMed
  275. Le TM et al. 2018. Journal of neurochemistry. 145(2):139-153 . PubMed
  276. Lee EKS, et al. 2018. Cell Host Microbe. 23:121. PubMed
  277. Ma Y, et al. 2020. Front Immunol. 11:586685. PubMed
  278. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  279. Guarnerio J, et al. 2018. Nat Commun. 9:66. PubMed
  280. Wolf Y, et al. 2019. Cell. 179:219. PubMed
  281. Wang H, et al. 2022. J Cancer. 13:2126. PubMed
  282. Zhang SJ, et al. 2021. Adv Sci (Weinh). 8:2003410. PubMed
  283. Zhang L, et al. 2021. Mol Ther. 29:744. PubMed
  284. Andreata F, et al. 2021. STAR Protoc. 2:100831. PubMed
  285. Ichinose M, et al. 2021. Sci Rep. 7200:11. PubMed
  286. Zhang B, et al. 2021. Front Neurol. 607370:12. PubMed
  287. Dingler FA, et al. 2020. Mol Cell. . PubMed
  288. Wan Y, et al. 2020. Cell Rep. 33:108346. PubMed
  289. Badgujar DC, et al. 2020. PLoS Pathog. 16:e1009016. PubMed
  290. Li CY, et al. 2022. Int J Mol Sci. 23:. PubMed
  291. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  292. Xu X, et al. 2020. Chin Med. 15:33. PubMed
  293. Shakya S, et al. 2020. MethodsX. 7:101027. PubMed
  294. Nederlof R, et al. 2022. Front Immunol. 13:908023. PubMed
  295. Kataru RP, et al. 2021. Sci Signal. 14:. PubMed
  296. Li Z, et al. 2022. Nat Commun. 13:1845. PubMed
  297. Li Y, et al. 2020. Nat Commun. 2.350694444. PubMed
  298. Gabitova-Cornell L, et al. 2020. Cancer Cell. 38(4):567-583.e11. PubMed
  299. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  300. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  301. Johnson DC, et al. 2018. Nat Med. 24:1151. PubMed
  302. Sefik E, et al. 2022. Nature. 606:585. PubMed
  303. Leinroth AP, et al. 2022. Cell Rep. 39:110785. PubMed
  304. Doughty D, et al. 2022. Exp Biol Med (Maywood). 247:1433. PubMed
  305. Du M, et al. 2022. Cancer Sci. 113:2974. PubMed
  306. Grégoire C, et al. 2022. Immunity. 55:1216. PubMed
  307. Tao X, et al. 2022. EMBO J. 41:e110439. PubMed
  308. Blanco LP, et al. 2022. Arthritis Rheumatol. 74:1971. PubMed
  309. Li X, et al. 2022. Cell Mol Gastroenterol Hepatol. 14:1077. PubMed
  310. Hindy G, et al. 2022. J Clin Invest. 132: . PubMed
  311. Roy IM, et al. 2022. iScience. 25:105171. PubMed
  312. Mendivil-Perez M, et al. 2022. Med Oncol. 40:15. PubMed
  313. Chen X, et al. 2022. J Extracell Vesicles. 11:e12279. PubMed
  314. Zheng Z, et al. 2022. Cells. 11: . PubMed
  315. Voit RA, et al. 2023. Nat Immunol. 24:69. PubMed
  316. Varshney R, et al. 2023. iScience. 26:105750. PubMed
  317. Cheng P, et al. 2023. Pharmacol Res. 188:106643. PubMed
  318. Jin SM, et al. 2023. Nat Nanotechnol. :. PubMed
  319. Chen L, et al. 2023. Bioeng Transl Med. 8:e10377. PubMed
  320. Stravokefalou V, et al. 2023. Front Immunol. 13:1014802. PubMed
  321. Zhao Y, et al. 2023. Sci Adv. 9:eabo1360. PubMed
  322. Liu X, et al. 2022. Pain. 163:508. PubMed
  323. González H, et al. 2022. Cell. 185:729. PubMed
  324. Mecklenburg J, et al. 2022. Brain Behav Immun. 101:246. PubMed
  325. Na E, et al. 2022. Am J Physiol Lung Cell Mol Physiol. 322:L550. PubMed
  326. Ma Y, et al. 2022. Am J Physiol Heart Circ Physiol. 322:H622. PubMed
  327. Ajay AK, et al. 2022. Cell Rep. 38:110473. PubMed
  328. Mise Y, et al. 2022. Carcinogenesis. 43:647. PubMed
  329. Pfeifhofer-Obermair C, et al. 2022. Bio Protoc. 12:e4378. PubMed
  330. Hanuscheck N, et al. 2022. J Exp Med. 219:. PubMed
  331. Klawitter M, et al. 2022. Int J Mol Sci. 23:. PubMed
  332. Zheng Y, et al. 2022. Proc Natl Acad Sci U S A. 119:e2121077119. PubMed
  333. Bowley TY, et al. 2022. Cancer Res Commun. 2:1436. PubMed
  334. Chen Y, et al. 2022. Am J Cancer Res. 12:5286. PubMed
  335. Zhang Y, et al. 2023. Invest Ophthalmol Vis Sci. 64:1. PubMed
  336. Sparbier CE, et al. 2023. Nat Cell Biol. 25:258. PubMed
  337. Li Y, et al. 2023. Adv Mater. 35:e2208923. PubMed
  338. Li M, et al. 2023. Front Immunol. 14:1087923. PubMed
  339. Chen H, et al. 2023. Nat Commun. 14:941. PubMed
  340. Ferriz M, et al. 2023. STAR Protoc. 4:102079. PubMed
  341. Volkova MV, et al. 2023. Int J Mol Sci. 24:. PubMed
  342. Solier S, et al. 2023. Int J Mol Sci. 24:. PubMed
  343. Li L, et al. 2023. iScience. 26:106095. PubMed
  344. Cheong LY, et al. 2023. Nat Commun. 14:1213. PubMed
  345. Xu H, et al. 2023. Acta Pharm Sin B. 13:678. PubMed
  346. Kozlovski S, et al. 2023. Front Immunol. 13:1041552. PubMed
  347. Rege SV, et al. 2023. Commun Biol. 6:292. PubMed
  348. Wang Y, et al. 2023. J Nanobiotechnology. 21:109. PubMed
  349. Zhang X, et al. 2023. Front Immunol. 14:1116749. PubMed
  350. Kim BH, et al. 2023. Sci Rep. 13:6577. PubMed
  351. Li T, et al. 2023. Nat Commun. 14:2498. PubMed
  352. Kase N, et al. 2023. Front Cell Dev Biol. 11:1022081. PubMed
  353. Huang T, et al. 2023. Cell Death Dis. 14:354. PubMed
  354. Guo X, et al. 2023. Mol Immunol. 160:32. PubMed
  355. Wang X, et al. 2023. Nature. 618:808. PubMed
  356. Akasaka H, et al. 2023. JCI Insight. 8:. PubMed
  357. J Gautam, X Zhang, Y Yao 2016. Sci Rep. 6:36450. PubMed
  358. Hulsebus HJ, et al. 2022. Front Immunol. 13:884719. PubMed
  359. Li X, et al. 2022. Nat Commun. 13:2794. PubMed
  360. El-Hindi K, et al. 2022. Int J Mol Sci. 23:. PubMed
  361. Qi Z, et al. 2022. Nat Commun. 13:182. PubMed
  362. Ma J, et al. 2020. Adv Sci (Weinh). 7:2000609. PubMed
  363. Sharma GP, et al. 2021. PLoS One. 16:e0259042. PubMed
  364. Huang Z et al. 2017. Cell metabolism. 26(3):493-508 . PubMed
  365. McGill BE et al. 2018. The Journal of Neuroscience. 38(1):200-219 . PubMed
  366. Hofmann I, et al. 2022. J Pharmacol Exp Ther. Online ahead of print. PubMed
  367. Prado C, et al. 2021. J Neuroinflammation. 18:292. PubMed
  368. Wang M, et al. 2022. Theranostics. 12:4513. PubMed
  369. Adachi Y, et al. 2022. Nat Commun. 13:5117. PubMed
  370. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  371. Tcheng M, et al. 2021. Blood. 137:3518. PubMed
  372. Zhu H, et al. 2018. Elife. 7:. PubMed
  373. Bauer KM, et al. 2022. JCI Insight. 7:. PubMed
  374. Sepe JJ, et al. 2022. JACC Basic Transl Sci. 7:915. PubMed
  375. Abdala-Valencia H, et al. 2014. Am J Physiol Lung Cell Mol Physiol. 307:482. PubMed
  376. Shao Y, et al. 2019. Diabetes. 68:2131. PubMed
  377. Lee AK, et al. 2020. Radiat Res. 193:305. PubMed
  378. Pan D, et al. 2022. Cancer Res. 82:2748. PubMed
  379. Rao E, et al. 2021. Sci Immunol. 6:. PubMed
  380. Saito S, et al. 2020. Nutrients. 12:. PubMed
  381. Liu X, et al. 2020. Nature. . PubMed
  382. Liang W, et al. 2020. Nat Commun. 4.563888889. PubMed
  383. Choi H et al. 2019. Cell Rep. 27(3):806-819 . PubMed
  384. Agelidis A, et al. 2019. Front Immunol. 10:500. PubMed
  385. Neumann AM et al. 2017. PloS one. 12(11):e0187330 . PubMed
  386. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  387. Ohigashi I, et al. 2020. Cell Reports. 29(9):2901-2916.e6.. PubMed
  388. Ihara S, et al. 2022. PLoS Negl Trop Dis. 16:e0010323. PubMed
  389. Talma N, et al. 2021. Aging Cell. 20:e13450. PubMed
  390. Zhao G, et al. 2020. Sci Adv. 6:00. PubMed
  391. Evren E, et al. 2020. Immunity. 54(2):259-275.e7. PubMed
  392. Wosczyna MN, et al. 2021. Cell Stem Cell. 28(7):1323-1334.e8. PubMed
  393. Pan H, et al. 2020. Mol Psychiatry. . PubMed
  394. Wang X, et al. 2021. Front Cell Dev Biol. 632805:9. PubMed
  395. Zhang Q, et al. 2019. PLoS Biol. 17:e3000330. PubMed
  396. Zhang C, et al. 2020. Cell Metabolism. 31(1):148-161.e5.. PubMed
  397. Lu Y, et al. 2020. Cell. 180(6):1081-1097. PubMed
  398. Francian A, et al. 2021. J Drug Target. 29:754. PubMed
  399. Johansen AZ, et al. 2022. Pharmaceutics. 14:. PubMed
  400. Rolfes S, et al. 2020. Neurobiol Dis. 144:105024. PubMed
  401. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  402. Han C, et al. 2021. Cell Reports. 34(6):108706. PubMed
  403. Meixiong J et al. 2019. Immunity. 50(5):1163-1171 . PubMed
  404. Xiao X, et al. 2019. Cell Discov. 5:2. PubMed
  405. Dai B, et al. 2022. Theranostics. 12:7603. PubMed
  406. Davidson S, et al. 2020. Cell Reports. 31(7):107628. PubMed
  407. Dane EL, et al. 2022. Nat Mater. 21:710. PubMed
  408. Yao L, et al. 2021. J Bone Miner Res. 36:1159. PubMed
  409. Koujah L, et al. 2021. Ocul Surf. 21:238. PubMed
  410. Kumari A, et al. 2022. Sci Rep. 12:15273. PubMed
  411. Li P, et al. 2021. Nat Immunol. 22:1107. PubMed
  412. Zhang X, et al. 2022. Cells. 11:. PubMed
  413. Kucinski I, et al. 2020. EMBO J. :e104983. PubMed
  414. Müller A, et al. 2020. J Clin Invest. 5765:130. PubMed
  415. Liang Z, et al. 2020. Pain. 161:2089. PubMed
  416. Zhang W, et al. 2021. Cell Prolif. 54:e13058. PubMed
  417. Gui J, et al. 2020. Nat Cancer. 1:603. PubMed
  418. Hore ZL, et al. 2021. Wellcome Open Res. 6:68. PubMed
  419. Emgård J, et al. 2018. Immunity. 143:419. PubMed
  420. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  421. Feng Y, et al. 2018. Kidney Dis (Basel). 4:95. PubMed
  422. Wosczyna MN et al. 2019. Cell Rep. 27(7):2029-2035 . PubMed
  423. Plein A, et al. 2018. Nature. 562:223. PubMed
  424. Kobayashi S, et al. 2019. J Immunol. 203:1447. PubMed
  425. Green DP, et al. 2019. Neuron. 101:412. PubMed
  426. Zein HS, et al. 2022. Sci Rep. 12:4834. PubMed
  427. Luo W, et al. 2022. Front Immunol. 13:816761. PubMed
  428. Kusuyama J, et al. 2021. Cell Metabolism. 33(5):939-956.e8. PubMed
  429. Deng Z, et al. 2017. Oncogene. 36:639. PubMed
  430. Barman PK, et al. 2019. J Immunol. 202:2720. PubMed
  431. Lim D, et al. 2018. Front Physiol. 9:47. PubMed
  432. Cervera–Carrascon V, et al. 2020. Oncoimmunology. 9:1761229. PubMed
  433. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  434. Gañán-Gómez I, et al. 2022. Nat Med. . PubMed
  435. Chin AL, et al. 2021. Nat Commun. 12:5138. PubMed
  436. Hu J, et al. 2020. Theranostics. 7.154166667. PubMed
  437. Li J, et al. 2020. Elife. 9:00. PubMed
  438. Rosa JM, et al. 2021. British Journal of Pharmacology. . PubMed
  439. Derecka M, et al. 2020. Nat Immunol. 261:21. PubMed
  440. Morimoto A, et al. 2021. Nat Commun. 12:2136. PubMed
  441. Poillet-Perez L, et al. 2020. Nat Cancer. 1:923. PubMed
  442. Srivastava S, et al. 2019. Cancer Cell. 35:489. PubMed
  443. Wang ECE, et al. 2019. Cell Stem Cell. 24:654. PubMed
  444. Zhang K, et al. 2014. PLoS Pathog. 10:1004385. PubMed
  445. Mencarelli A, et al. 2016. Sci Rep. 6:30802. PubMed
  446. Lu X, et al. 2016. Nat Commun. 7: 12719. PubMed
  447. Goldfarb Y, et al. 2021. J Exp Med. 218:. PubMed
  448. Zeng Q, et al. 2022. Front Immunol. 13:740805. PubMed
  449. Ye P, et al. 2022. Front Cardiovasc Med. 8:810477. PubMed
  450. Brigas HC, et al. 2021. Cell Reports. 36(9):109574. PubMed
  451. Zhu H, et al. 2021. Cell Metabolism. :. PubMed
  452. Nguyen PT, et al. 2020. Cell. 182(2):388-403.e15. PubMed
  453. Liu CY, et al. 2020. Cell Rep. 33:108275. PubMed
  454. Wan X, et al. 2018. Nature. 560:107. PubMed
  455. Al–Zaher AA, et al. 2018. Mol Ther Oncolytics. 0.376388889. PubMed
  456. Hepler C et al. 2018. eLife. 7 pii: e39636. PubMed
  457. Burr ML, et al. 2019. Cancer Cell. 36:385. PubMed
  458. Wang F, et al. 2019. MAbs. 12:1685350. PubMed
  459. Ji DX, et al. 2019. Nat Microbiol. 1.644444444. PubMed
  460. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  461. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  462. Sefik E, et al. 2021. Nat Biotechnol. . PubMed
  463. Watanabe Y, et al. 2020. J Biol Chem. 295:17632. PubMed
  464. Engler AE, et al. 2020. Cell Reports. 33(13):108553. PubMed
  465. Ruan C, et al. 2020. Brain Behav Immun. 83:180. PubMed
  466. Cai Y, et al. 2019. Cell Rep. 27:3034. PubMed
  467. Crowell PD et al. 2019. Cell Rep. 28(6):1499-1510 . PubMed
  468. Maetzig T, et al. 2017. Mol Ther. 25:606. PubMed
  469. Coronel MM, et al. 2020. Sci Adv. 6:eaba5573. PubMed
  470. Pundir P, et al. 2020. Cell Host & Microbe. 26(1):114-122. PubMed
  471. Milner MT, et al. 2022. STAR Protoc. 3:101295. PubMed
  472. Zhang X, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  473. Xiao L, et al. 2021. Clin Cancer Res. 27:4338. PubMed
  474. Kotas ME, et al. 2022. JCI Insight. :. PubMed
  475. Rashid MH, et al. 2021. Oncol Rep. 45:1171. PubMed
  476. Jiang Y, et al. 2021. Cell Death Differ. 28:3009. PubMed
  477. Agelidis A, et al. 2021. JCI Insight. 6: . PubMed
  478. Monaghan KL, et al. 2020. J Vis Exp. . PubMed
  479. Yamakawa D, et al. 2021. Cell Reports. 34(10):108817. PubMed
  480. Gastelum‐Aviña P et al. 2016. Journal of immunological methods. 438:42-50 . PubMed
  481. Zhou J, et al. 2019. Nat Commun. 10:2427. PubMed
  482. Yu X, et al. 2019. Nat Commun. 10:574. PubMed
  483. Su S et al. 2018. Cell. 175(2):442-457 . PubMed
  484. Galle-Treger L, et al. 2016. Nat Commun. 7:13202. PubMed
  485. Minhas PS, et al. 2021. Nature. 590:122. PubMed
  486. Zhang X, et al. 2021. Mol Cancer Res. 19:1076. PubMed
  487. Liu S, et al. 2022. J Neuroinflammation. 19:35. PubMed
  488. Xiao Y, et al. 2022. Nat Commun. 13:758. PubMed
  489. Ali S, et al. 2021. PLoS One. 16:e0246646. PubMed
  490. Yang Z, et al. 2021. Nat Commun. 12:4852. PubMed
  491. Long JT, et al. 2022. Elife. 11:. PubMed
  492. Bravo-Caparrós I, et al. 2020. FASEB J. 34:5951. PubMed
  493. Zhang P, et al. 2022. Nat Commun. 13:1588. PubMed
  494. Jiang Q, et al. 2020. JCI Insight. 5:00. PubMed
  495. Hasegawa T, et al. 2020. Sci Rep. 10:13480. PubMed
  496. Johnson DC, et al. 2020. Cell Death Dis. 0.894444444. PubMed
  497. Li CM, et al. 2020. Cell Reports. 33(13):108566. PubMed
  498. Zhang L, et al. 2021. iScience. 24(9):102942. PubMed
  499. Hu Y, et al. 2021. Cell Death Dis. 12:743. PubMed
  500. Wang Z et al. 2018. Immunity. 49(1):80-92 . PubMed
  501. Sarvi S et al. 2018. Cell chemical biology. 25(12):1456-1469 . PubMed
  502. Sirvinskas D, et al. 2022. iScience. 25:104202. PubMed
  503. Ito K, et al. 2014. Proc Natl Acad Sci U S A. 111:3080. PubMed
  504. Saunders L, et al. 2015. Sci Transl Med. 7: 302ra136. PubMed
  505. Qi F, et al. 2019. Front Microbiol. 2.140277778. PubMed
  506. Yu JM, et al. 2019. Nat Commun. 4.388888889. PubMed
  507. Hou Y, et al. 2021. Sci Transl Med. 13:. PubMed
  508. Xu G, et al. 2022. Front Pharmacol. 13:896601. PubMed
  509. Zhou J, et al. 2022. Int J Oncol. 61: . PubMed
  510. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  511. Song J, et al. 2021. Am J Physiol Heart Circ Physiol. 320:H323. PubMed
  512. Zeis P, et al. 2020. Immunity. 53:775. PubMed
  513. Ben-Yehuda H, et al. 2021. Mol Neurodegener. 16:39. PubMed
  514. Kim H, et al. 2020. Biomed Rep. 0.589583333. PubMed
  515. Li Z, et al. 2022. Nat Commun. 13:6321. PubMed
  516. Ferrer-Font L, et al. 2020. Elife. 9:. PubMed
  517. Sakai H, et al. 2022. iScience. 25:103928. PubMed
  518. Walker MT, et al. 2021. Front. Allergy. 2:. PubMed
  519. Kataru RP, et al. 2022. Front Aging. 3:864860. PubMed
  520. Pan Y, et al. 2021. Br J Pharmacol. 178:4907. PubMed
  521. Zheng B, et al. 2021. Bioact Mater. 6:3879. PubMed
  522. Ovadya Y, et al. 2018. Nat Commun. 9:5435. PubMed
  523. Tomimatsu M, et al. 2022. Sci Rep. 12:16656. PubMed
  524. Chen M, et al. 2019. Cell Stem Cell. 25:501. PubMed
  525. Hameed H, et al. 2022. Int J Mol Sci. 23:. PubMed
  526. Ding R, et al. 2022. J Neuroinflammation. 19:137. PubMed
  527. Liu R, et al. 2020. Eur J Vasc Endovasc Surg. 60:254. PubMed
  528. Fan ZP, et al. 2021. Front Immunol. 12:743354. PubMed
  529. Okada R, et al. 2021. EBioMedicine. 67:103345. PubMed
  530. Sema Kurtulus et al. 2018. Immunity. 50(1):181-194 . PubMed
  531. Liu L et al. 2018. Cell stem cell. 23(4):544-556 . PubMed
  532. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  533. Chao Y, et al. 2020. Sci Adv. 6:eaaz4204. PubMed
  534. Kataru RP, et al. 2019. Cancer Immunol Res. 7:1345. PubMed
  535. Krivtsov AV, et al. 2020. Cancer Cell. 36(6):660-673.e11.. PubMed
  536. Hu X, et al. 2020. Neoplasia. 1.290972222. PubMed
  537. Banskota S, et al. 2021. Inflamm Bowel Dis. 27:914. PubMed
  538. Ruan Y, et al. 2022. Exp Ther Med. 23:47. PubMed
  539. Wang R, et al. 2022. J Immunother Cancer. 10:. PubMed
  540. Liao X, et al. 2022. JCI Insight. 7:. PubMed
  541. Kelley WJ, et al. 2022. JCI Insight. 7: . PubMed
  542. Simoes Eugénio M, et al. 2020. Cancers (Basel). 12:00. PubMed
  543. Chen L, et al. 2021. Theranostics. 11:6668. PubMed
  544. Sugita Y, et al. 2021. Oncol Rep. 45:. PubMed
  545. Ding L et al. 2018. Cell reports. 25(11):2972-2980 . PubMed
  546. Hao T, et al. 2019. Nat Commun. 10:3665. PubMed
  547. Zegarra‐Ruiz DF et al. 2018. Cell host & microbe. 25(1):113-127 . PubMed
  548. Cerina M, et al. 2017. Brain Behav Immun. 59:103-117. PubMed
  549. Tr änkner D, et al. 2019. Cell Rep. 29:791. PubMed
  550. Lee C, et al. 2020. Front Immunol. 11:77. PubMed
  551. Eckert EC, et al. 2020. Mol Ther Oncolytics. 0.710416667. PubMed
  552. Zhou Y, et al. 2022. Theranostics. 12:5488. PubMed
  553. Sheng D, et al. 2022. J Immunother Cancer. 10:. PubMed
  554. El-Obeid A, et al. 2021. Exp Ther Med. 22:1081. PubMed
  555. Sharma R, et al. 2021. J Neuroinflammation. 72:18. PubMed
  556. Watanabe Y, et al. 2020. J Biol Chem. . PubMed
  557. Sheng J, et al. 2021. eLife. 10:00. PubMed
  558. Poillet–Perez L, et al. 2018. Nature. 563:569. PubMed
  559. Padhye A, et al. 2019. Sci Rep. 9:4819. PubMed
  560. Shao Y, et al. 2019. Stem Cells. 37:1331. PubMed
  561. Krotova K, et al. 2019. Mol Ther Oncolytics. 15:166. PubMed
  562. Gupta R, et al. 2020. Cell Stem Cell. 26:527. PubMed
  563. Spiljar M, et al. 2021. Cell Metab. 33:2231. PubMed
  564. Li M, et al. 2020. Nat Commun. 4051:11. PubMed
  565. Le TM et al. 2018. Journal of neurochemistry. 145(2):139-153 . PubMed
  566. Lee EKS, et al. 2018. Cell Host Microbe. 23:121. PubMed
  567. Ma Y, et al. 2020. Front Immunol. 11:586685. PubMed
  568. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  569. Guarnerio J, et al. 2018. Nat Commun. 9:66. PubMed
  570. Wolf Y, et al. 2019. Cell. 179:219. PubMed
  571. Wang H, et al. 2022. J Cancer. 13:2126. PubMed
  572. Zhang SJ, et al. 2021. Adv Sci (Weinh). 8:2003410. PubMed
  573. Zhang L, et al. 2021. Mol Ther. 29:744. PubMed
  574. Andreata F, et al. 2021. STAR Protoc. 2:100831. PubMed
  575. Ichinose M, et al. 2021. Sci Rep. 7200:11. PubMed
  576. Zhang B, et al. 2021. Front Neurol. 607370:12. PubMed
  577. Dingler FA, et al. 2020. Mol Cell. . PubMed
  578. Wan Y, et al. 2020. Cell Rep. 33:108346. PubMed
  579. Badgujar DC, et al. 2020. PLoS Pathog. 16:e1009016. PubMed
  580. Li CY, et al. 2022. Int J Mol Sci. 23:. PubMed
RRID
AB_312972 (BioLegend Cat. No. 103107)
AB_312973 (BioLegend Cat. No. 103108)

Antigen Details

Structure
Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution

All hematopoietic cells except mature erythrocytes and platelets

Function
Phosphatase, T and B cell activation
Ligand/Receptor
Galectin-1, CD2, CD3, CD4, TCR, CD22, Thy-1
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85.
3. Kishihara K, et al. 1993. Cell 74:143.
4. Pulido R, et al. 1988. J. Immunol. 140:3851.

Gene ID
19264 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

Other Formats

View All CD45 Reagents Request Custom Conjugation
Description Clone Applications
PE anti-mouse CD45 30-F11 FC
PE/Cyanine5 anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 30-F11 FC,IHC-F,CyTOF®,IP,CMCD,IHC,WB
PE/Cyanine7 anti-mouse CD45 30-F11 FC
PE/Dazzle™ 594 anti-mouse CD45 30-F11 FC
Brilliant Violet 711™ anti-mouse CD45 30-F11 FC
Brilliant Violet 785™ anti-mouse CD45 30-F11 FC
Brilliant Violet 650™ anti-mouse CD45 30-F11 FC
APC/Fire™ 750 anti-mouse CD45 30-F11 FC
Brilliant Violet 750™ anti-mouse CD45 30-F11 FC
TotalSeq™-A0096 anti-mouse CD45 30-F11 PG
Spark Blue™ 550 anti-mouse CD45 30-F11 FC
TotalSeq™-B0096 anti-mouse CD45 30-F11 PG
Ultra-LEAF™ Purified anti-mouse CD45 30-F11 FC,CyTOF®,IP,CMCD,IHC,WB
Spark NIR™ 685 anti-mouse CD45 30-F11 FC
TotalSeq™-C0096 anti-mouse CD45 30-F11 PG
Spark YG™ 570 anti-mouse CD45 30-F11 IHC-F
PE/Fire™ 700 anti-mouse CD45 30-F11 FC
PE/Fire™ 640 anti-mouse CD45 30-F11 FC
APC/Fire™ 810 anti-mouse CD45 30-F11 FC
APC anti-mouse CD45 30-F11 FC
FITC anti-mouse CD45 30-F11 FC
Biotin anti-mouse CD45 30-F11 FC
APC/Cyanine7 anti-mouse CD45 30-F11 FC
Alexa Fluor® 488 anti-mouse CD45 30-F11 FC,SB
Pacific Blue™ anti-mouse CD45 30-F11 FC
Alexa Fluor® 700 anti-mouse CD45 30-F11 FC,SB
Alexa Fluor® 647 anti-mouse CD45 30-F11 FC,ICC,IHC,3D IHC,SB
PerCP/Cyanine5.5 anti-mouse CD45 30-F11 FC
PerCP anti-mouse CD45 30-F11 FC
Alexa Fluor® 594 anti-mouse CD45 30-F11 IHC-F,FC,3D IHC
Brilliant Violet 421™ anti-mouse CD45 30-F11 FC,SB
Brilliant Violet 570™ anti-mouse CD45 30-F11 FC
Brilliant Violet 510™ anti-mouse CD45 30-F11 FC
Brilliant Violet 605™ anti-mouse CD45 30-F11 FC
Purified anti-mouse CD45 (Maxpar® Ready) 30-F11 FC,CyTOF®
Spark Violet™ 538 anti-mouse CD45 30-F11 FC
Spark YG™ 593 anti-mouse CD45 30-F11 FC
Spark Blue™ 574 anti-mouse CD45 Antibody 30-F11 FC
Spark Blue™ 515 anti-mouse CD45 30-F11 FC
Spark UV™ 387 anti-mouse CD45 30-F11 FC
PE/Fire™ 810 anti-mouse CD45 30-F11 FC
Spark PLUS UV395™ anti-mouse CD45 30-F11 FC
Spark Red™ 718 anti-mouse CD45 30-F11 FC
Spark PLUS V475™ anti-mouse CD45 Antibody 30-F11 FC
Spark YG™ 581 anti-mouse CD45 (Flexi-Fluor™) 30-F11 FC
StarBright UltraViolet 740 anti-mouse CD45 30-F11 FC
Go To Top Version: 2    Revision Date: 05/14/2013

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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