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PE anti-mouse CD3 Antibody PE anti-mouse CD3 Antibody

Pricing & Availability
Clone
17A2 (See other available formats)
Regulatory Status
RUO
Other Names
T cell antigen receptor complex, T3
Isotype
Rat IgG2b, κ
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Product Citations
publications
17A2_PE_021606
C57BL/6 mouse splenocytes stained with 17A2 PE
  • 17A2_PE_021606
    C57BL/6 mouse splenocytes stained with 17A2 PE
Compare all formats See PE spectral data
Cat # Size Price Quantity Check Availability Save
100206 200 µg SEK1202
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100205 50 µg SEK513
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Description

CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
γδTCR-positive T-T hybridoma D1
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported application (for relevant formats) include: spatial biology (IBEX)1,2.

Application References
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  2. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
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  187. Shen S, et al. 2018. Pain Med. 19:686. PubMed
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  196. Baptista AP et al. 2019. Immunity. 50(5):1188-1201 . PubMed
  197. Kunimura K, et al. 2020. Cell Reports. 29(9):2823-2834.e7.. PubMed
  198. Bedi B, et al. 2012. Proc Natl Acad Sci U S A. 109:275. PubMed
  199. Xu ZH, et al. 2021. Mediators Inflamm. 2021:8856326. PubMed
  200. Lutzmann M, et al. 2019. Cell Rep. 28:2851. PubMed
  201. Periasamy S, et al. 2017. Nat Commun. 8:15564. PubMed
  202. Lechner AJ et al. 2017. Cell stem cell. 21(1):120-134 . PubMed
  203. Shu T, et al. 2022. Eur Respir J. Online ahead of print. PubMed
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  205. Jazowiecka-Rakus J, et al. 2021. Cancers (Basel). 13:. PubMed
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  207. Ma C, et al. 2018. Science. 360:eaan5931. PubMed
  208. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  209. Mathur S, et al. 2021. JCI Insight. 6:. PubMed
  210. Ohyagi M, et al. 2021. Nat Commun. 12:7344. PubMed
  211. Yan X, et al. 2022. Int J Biol Sci. 18:585. PubMed
  212. Helm M, et al. 2022. Life (Basel). 12:. PubMed
  213. Tu X, et al. 2022. Nat Commun. 13:6977. PubMed
  214. Schmidt D, et al. 2016. PLoS One. 11: 0159059. PubMed
  215. He C, et al. 2020. Clin Transl Med. 10:e39. PubMed
  216. Kuang Z, et al. 2020. Antib Ther. 3:227. PubMed
  217. Hu D, et al. 2021. J Cell Mol Med. 25:2900. PubMed
  218. Vannini N, et al. 2019. Cell Stem Cell. 24:405. PubMed
  219. Biram A, et al. 2020. Cell Rep. 30:1910. PubMed
  220. Delgado‐Benito V et al. 2018. Molecular cell. 72(4):636-649 . PubMed
  221. Mariani SA, et al. 2019. Immunity. 50:1439. PubMed
  222. Stivala S, et al. 2019. J Clin Invest. 130:1596. PubMed
  223. Zhang D, et al. 2020. Signal Transduct Target Ther. 5:24. PubMed
  224. Wang F, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:257. PubMed
  225. Zhou Y, et al. 2022. Nat Commun. 13:2906. PubMed
  226. Stutchfield B, et al. 2015. Gastroenterology. 149: 1896-1909.e14. PubMed
  227. Koren N, et al. 2021. Cell Host Microbe. 29(2):197-209.e5. PubMed
  228. Domingos-Pereira S, et al. 2019. Cancer Immunol Res. 7:621. PubMed
  229. Lin H, et al. 2019. Infect Immun. 87:e00055-19. PubMed
  230. Pedraza–Zamora CP, et al. 2017. Parasite Immunol. 39:4. PubMed
  231. McAlpine CS, et al. 2021. Nature. 595:701. PubMed
  232. Wu L, et al. 2022. Theranostics. 12:842. PubMed
  233. Goldman E, et al. 2021. Cells. 10:. PubMed
  234. Cassidy BR, et al. 2020. J Neuroinflammation. 17:259. PubMed
  235. Wu J, et al. 2020. Immunity. 53:115. PubMed
  236. Doonan J, et al. 2019. Nat Commun. 10:1554. PubMed
  237. Halpern KB, et al. 2018. Nat Biotechnol. 36:962. PubMed
  238. Deng M, et al. 2020. Nat Commun. 11:2193. PubMed
  239. Paul S, et al. 2018. Appl Microbiol Biotechnol. 102:8895. PubMed
  240. Shi R, et al. 2022. Theranostics. 12:875. PubMed
  241. Cheng B, et al. 2022. Cancer Commun (Lond). 42:17. PubMed
  242. Glaros V, et al. 2021. Immunity. 54:2005. PubMed
  243. Hu J, et al. 2022. J Neuroinflammation. 19:71. PubMed
  244. Chen Y, et al. 2015. PLoS One. 10: 0135217. PubMed
  245. Li Y, et al. 2020. Cell Stem Cell. 27(5):732-747.e7. PubMed
  246. He Y, et al. 2021. Cell Metabolism. 33(5):988-1000.e7. PubMed
  247. Marinescu CI, et al. 2021. Stem Cell Res Ther. 12:319. PubMed
  248. O'Connor T, et al. 2020. Cancer Cell. 36(3):250-267. PubMed
  249. Frodermann V, et al. 2019. Nat Med. 25:1761. PubMed
  250. Chauveau A, et al. 2020. Immunity. 52:794. PubMed
  251. Mishra BB, et al. 2017. Nat Microbiol. 2:17072. PubMed
  252. Kim JH, et al. 2019. Mol Med. 25:33. PubMed
  253. Pedraza-Zamora C, et al. 2017. Parasite Immunol. 10.1111/pim.12420. PubMed
  254. Fang E, et al. 2022. MedComm (2020). 3:e117. PubMed
  255. Harnett MM, et al. 2022. Front Immunol. 13:953053. PubMed
  256. Zuo S, et al. 2021. J Immunother Cancer. 9:. PubMed
  257. Xiang W, et al. 2018. Nat Commun. 9:2574. PubMed
  258. Cho K, et al. 2021. iScience. 24:103117. PubMed
  259. Zhou Z, et al. 2022. Infect Immun. 90:e0045321. PubMed
  260. Bullard BL, et al. 2022. NPJ Vaccines. 7:65. PubMed
  261. Tomala J, et al. 2020. Methods Mol Biol. 2111:101. PubMed
  262. Nikolos F, et al. 2022. Nat Commun. 13:1487. PubMed
  263. Lewandowski JP, et al. 2020. Genome Biol. 1.039583333. PubMed
  264. Kruta M, et al. 2021. Cell Stem Cell. :. PubMed
  265. Huang Z, et al. 2021. Nat Commun. 12:145. PubMed
  266. Zou D, et al. 2020. EBioMedicine. 52:102652. PubMed
  267. Sanmarco LM, et al. 2021. Nature. 590:473. PubMed
  268. Rozanski C, et al. 2015. J Immunol. 194:4717. PubMed
  269. Sun J et al. 2018. Cell stem cell. 23(3):355-369 . PubMed
  270. Huang L, et al. 2018. Exp Neurol. 300:41. PubMed
  271. Ding Y, et al. 2020. Evid Based Complement Alternat Med. 2020:9521073. PubMed
  272. Zhang T, et al. 2020. Cell. 180(6):1115-1129. PubMed
  273. Gamrekelashvili J, et al. 2021. Bio Protoc. 11:e4007. PubMed
  274. Feng Y, et al. 2022. J Nanobiotechnology. 20:193. PubMed
  275. Fang H, et al. 2020. Nat Commun. 4.661805556. PubMed
  276. Tummers B, et al. 2020. Immunity. 52(6):994-1006.e8. PubMed
  277. Winchell CG, et al. 2020. Front Immunol. 1.077083333. PubMed
  278. Chan WY, et al. 2019. Infect Immun. 87:. PubMed
  279. Wang W, et al. 2021. J Am Heart Assoc. 10:e019142. PubMed
  280. Olson B, et al. 2021. Brain Behav Immun. 97:102. PubMed
  281. Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
  282. Cai Z, et al. 2020. Cell Rep. 31:107816. PubMed
  283. Yamamura K, et al. 2017. Nat Commun. 8:13946. PubMed
  284. Hsieh Y, et al. 2014. Infect Immun . 82:2087. PubMed
  285. Yao C, et al. 2018. Autophagy. 1.854861111. PubMed
  286. Zhang MS, et al. 2022. Nat Commun. 13:954. PubMed
  287. Jazowiecka-Rakus J, et al. 2020. Mol Ther Oncolytics. 18:335. PubMed
  288. Chen H, et al. 2022. Front Pharmacol. 13:827520. PubMed
  289. Schneider A, et al. 2014. J Leukoc Biol. 96:857. PubMed
  290. Kim MY, et al. 2022. Nat Commun. 13:3296. PubMed
  291. Zhou H, et al. 2021. Cell Death Discov. 7:332. PubMed
  292. Zhou T, et al. 2021. Bioact Mater. 0.734027778. PubMed
  293. Uluçkan ö, et al. 2020. Cell Reports. 29(4):844-859.e3.. PubMed
  294. Zhang D, et al. 2020. Signal Transduct Target Ther. 5:24. PubMed
  295. Lu C, et al. 2020. Cancer Cell. 39(1):96-108.e6. PubMed
  296. Rodríguez L, et al. 2021. Biomolecules. 11: . PubMed
  297. Fathman J, et al. 2010. Proc Natl Acad Sci U S A. 107:3663. PubMed
  298. Hidalgo San Jose L, et al. 2020. Cell Rep. 30:69. PubMed
  299. Gundra UM, et al. 2017. Nat Immunol. 1.195833333. PubMed
  300. Sun Y, et al. 2022. iScience. 25:104846. PubMed
  301. Maulhardt HA, et al. 2020. Invest New Drugs. 1618:38. PubMed
  302. Yu H, et al. 2015. PLoS One. 10: 0143001. PubMed
  303. Crowe J, et al. 2020. PLoS Pathog. 16:e1008391. PubMed
  304. Gawish R, et al. 2022. Elife. 11:. PubMed
  305. Vannini N, et al. 2016. Nat Commun. 7:13125. PubMed
  306. Wu L, et al. 2020. Cancer Immunol Res. 710:8. PubMed
  307. Das A, et al. 2020. J Bone Miner Res. 36:199. PubMed
  308. He C, et al. 2021. Immunol Cell Biol. 99:611. PubMed
  309. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  310. Zuo S, et al. 2021. EBioMedicine. 64:103240. PubMed
  311. Zeng F, et al. 2021. J Invest Dermatol. 596:141. PubMed
  312. Guo S, et al. 2021. Frontiers in Immunology. 11:614667. PubMed
  313. Xiang W, et al. 2020. Signal Transduct Target Ther. 0.374305556. PubMed
  314. Hayashi K, et al. 2020. Nat Commun. 4.832638889. PubMed
RRID
AB_312663 (BioLegend Cat. No. 100206)
AB_312662 (BioLegend Cat. No. 100205)

Antigen Details

Structure
Ig superfamily, CD3/TCR, 20 kD
Distribution

Thymocytes (differentiation dependent), mature T cells, NK-T cells

Function
Antigen recognition, TCR signal transduction, T cell activation
Ligand/Receptor
Peptide antigen/MHC-complex
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Davis MM. 1990. Annu. Rev. Biochem. 59:475.
3. Weiss A, et al. 1994. Cell 76:263.

Gene ID
12502 View all products for this Gene ID
UniProt
View information about CD3 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.

Other Formats

View All CD3 Reagents Request Custom Conjugation
Description Clone Applications
Brilliant Violet 711™ anti-mouse CD3 17A2 FC
Biotin anti-mouse CD3 17A2 FC,IHC-F
PE/Dazzle™ 594 anti-mouse CD3 17A2 FC
APC/Fire™ 750 anti-mouse CD3 17A2 FC
Brilliant Violet 750™ anti-mouse CD3 17A2 FC
TotalSeq™-A0182 anti-mouse CD3 17A2 PG
TotalSeq™-B0182 anti-mouse CD3 17A2 PG
Spark Blue™ 550 anti-mouse CD3 17A2 FC
Spark NIR™ 685 anti-mouse CD3 17A2 FC
TotalSeq™-C0182 anti-mouse CD3 17A2 PG
APC/Fire™ 810 anti-mouse CD3 17A2 FC
PE/Fire™ 640 anti-mouse CD3 17A2 FC
Spark YG™ 570 anti-mouse CD3 17A2 IHC-F
PE/Fire™ 700 anti-mouse CD3 17A2 FC
FITC anti-mouse CD3 17A2 FC
PE anti-mouse CD3 17A2 FC
Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Alexa Fluor® 647 anti-mouse CD3 17A2 FC,IHC-F,3D IHC,SB
Test 17A2 5 17A2
Alexa Fluor® 488 anti-mouse CD3 17A2 FC,IHC-F,3D IHC
Pacific Blue™ anti-mouse CD3 17A2 FC
Alexa Fluor® 700 anti-mouse CD3 17A2 FC
PerCP/Cyanine5.5 anti-mouse CD3 17A2 FC
PE/Cyanine7 anti-mouse CD3 17A2 FC
APC/Cyanine7 anti-mouse CD3 17A2 FC
Brilliant Violet 421™ anti-mouse CD3 17A2 FC,ICC
Brilliant Violet 570™ anti-mouse CD3 17A2 FC
Brilliant Violet 650™ anti-mouse CD3 17A2 FC
Brilliant Violet 785™ anti-mouse CD3 17A2 FC
Brilliant Violet 510™ anti-mouse CD3 17A2 FC
APC anti-mouse CD3 17A2 FC
Ultra-LEAF™ Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Brilliant Violet 605™ anti-mouse CD3 17A2 FC
Alexa Fluor® 594 anti-mouse CD3 17A2 IHC-F,FC,3D IHC,SB
PE/Cyanine5 anti-mouse CD3 17A2 FC
Spark Blue™ 574 anti-mouse CD3 Antibody 17A2 FC
Spark Violet™ 423 anti-mouse CD3 17A2 FC
PE/Fire™ 810 anti-mouse CD3 17A2 FC
Spark Red™ 718 anti-mouse CD3 17A2 FC
Spark UV™ 387 anti-mouse CD3 17A2 FC
PerCP/Fire™ 780 anti-mouse CD3 Antibody 17A2 FC
PerCP anti-mouse CD3 Antibody 17A2 FC
Spark YG™ 581 anti-mouse CD3 (Flexi-Fluor™) 17A2 FC
Spark YG™ 593 anti-mouse CD3 (Flexi-Fluor™) Antibody 17A2 FC
Spark PLUS B488™ anti-mouse CD3 17A2 FC
Go To Top Version: 1    Revision Date: 11-30-2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Pricing & Availability
Clone
17A2 (See other available formats)
Regulatory Status
RUO
Other Names
T cell antigen receptor complex, T3
Isotype
Rat IgG2b, κ
Ave. Rating
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Product Citations
publications
17A2_PE_021606
C57BL/6 mouse splenocytes stained with 17A2 PE
  • 17A2_PE_021606
    C57BL/6 mouse splenocytes stained with 17A2 PE
Compare all formats See PE spectral data
Cat # Size Price Quantity Check Availability Save
100206 200 µg SEK1202
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100205 50 µg SEK513
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Description

CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
γδTCR-positive T-T hybridoma D1
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported application (for relevant formats) include: spatial biology (IBEX)1,2.

Application References
  1. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  2. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
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  4. Chan WY, et al. 2022. Infect Immun. 90:e0084618a. PubMed
  5. Wang D, et al. 2022. Cell Rep. 39:110587. PubMed
  6. Mirchandani AS, et al. 2022. Nat Immunol. 23:927. PubMed
  7. Yang K, et al. 2022. Sci Immunol. 7:eabn2888. PubMed
  8. McAlpine CS, et al. 2022. J Exp Med. 219: . PubMed
  9. TaSli PN, et al. 2022. J Food Biochem. 46:e14393. PubMed
  10. Shen Z, et al. 2022. EBioMedicine. 85:104285. PubMed
  11. Deng P, et al. 2022. J Clin Invest. 132: . PubMed
  12. Wei M, et al. 2022. Front Immunol. 13:1017574. PubMed
  13. Domingos-Pereira S, et al. 2022. Int J Mol Sci. 24: . PubMed
  14. Giannou AD, et al. 2023. Immunity. 56:125. PubMed
  15. Briukhovetska D, et al. 2023. Immunity. 56:143. PubMed
  16. Meacham CE, et al. 2022. Nat Cell Biol. 24:697. PubMed
  17. Zhao L, et al. 2022. Oncogene. 41:4200. PubMed
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  20. Zhang X, et al. 2023. Front Immunol. 14:1116749. PubMed
  21. Sun JY, et al. 2023. Sci Adv. 9:eade4110. PubMed
  22. Shi Y, et al. 2023. Nat Commun. 14:1884. PubMed
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  41. Bedi B, et al. 2012. Proc Natl Acad Sci U S A. 109:275. PubMed
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  141. Hidalgo San Jose L, et al. 2020. Cell Rep. 30:69. PubMed
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  143. Sun Y, et al. 2022. iScience. 25:104846. PubMed
  144. Maulhardt HA, et al. 2020. Invest New Drugs. 1618:38. PubMed
  145. Yu H, et al. 2015. PLoS One. 10: 0143001. PubMed
  146. Crowe J, et al. 2020. PLoS Pathog. 16:e1008391. PubMed
  147. Gawish R, et al. 2022. Elife. 11:. PubMed
  148. Vannini N, et al. 2016. Nat Commun. 7:13125. PubMed
  149. Wu L, et al. 2020. Cancer Immunol Res. 710:8. PubMed
  150. Das A, et al. 2020. J Bone Miner Res. 36:199. PubMed
  151. He C, et al. 2021. Immunol Cell Biol. 99:611. PubMed
  152. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  153. Zuo S, et al. 2021. EBioMedicine. 64:103240. PubMed
  154. Zeng F, et al. 2021. J Invest Dermatol. 596:141. PubMed
  155. Guo S, et al. 2021. Frontiers in Immunology. 11:614667. PubMed
  156. Xiang W, et al. 2020. Signal Transduct Target Ther. 0.374305556. PubMed
  157. Hayashi K, et al. 2020. Nat Commun. 4.832638889. PubMed
  158. Xu C, et al. 2017. Biochemical and Biophysical Research Communications. 10.1016/j.bbrc.2017.05.071. PubMed
  159. Xue G, et al. 2021. Cancer Cell. 39:1610. PubMed
  160. Hiyoshi H, et al. 2022. Cell Host Microbe. 30:163. PubMed
  161. Chan WY, et al. 2022. Infect Immun. 90:e0084618a. PubMed
  162. Wang D, et al. 2022. Cell Rep. 39:110587. PubMed
  163. Mirchandani AS, et al. 2022. Nat Immunol. 23:927. PubMed
  164. Yang K, et al. 2022. Sci Immunol. 7:eabn2888. PubMed
  165. McAlpine CS, et al. 2022. J Exp Med. 219: . PubMed
  166. TaSli PN, et al. 2022. J Food Biochem. 46:e14393. PubMed
  167. Shen Z, et al. 2022. EBioMedicine. 85:104285. PubMed
  168. Deng P, et al. 2022. J Clin Invest. 132: . PubMed
  169. Wei M, et al. 2022. Front Immunol. 13:1017574. PubMed
  170. Domingos-Pereira S, et al. 2022. Int J Mol Sci. 24: . PubMed
  171. Giannou AD, et al. 2023. Immunity. 56:125. PubMed
  172. Briukhovetska D, et al. 2023. Immunity. 56:143. PubMed
  173. Meacham CE, et al. 2022. Nat Cell Biol. 24:697. PubMed
  174. Zhao L, et al. 2022. Oncogene. 41:4200. PubMed
  175. Guo D, et al. 2023. Cell Biosci. 13:51. PubMed
  176. Fan NW, et al. 2023. FASEB J. 37:e22855. PubMed
  177. Zhang X, et al. 2023. Front Immunol. 14:1116749. PubMed
  178. Sun JY, et al. 2023. Sci Adv. 9:eade4110. PubMed
  179. Shi Y, et al. 2023. Nat Commun. 14:1884. PubMed
  180. Fiedler T, et al. 2023. J Neuroinflammation. 20:100. PubMed
  181. Li Y, et al. 2023. Front Cell Infect Microbiol. 13:1117230. PubMed
  182. Bhaskar A, et al. 2023. iScience. 26:106644. PubMed
  183. Wang Y, et al. 2023. iScience. 26:106630. PubMed
  184. Milighetti M, et al. 2023. iScience. 26:106937. PubMed
  185. Zuchtriegel G, et al. 2016. PLoS Biol. 14: 1002459. PubMed
  186. Baryawno N et al. 2019. Cell. 177(7):1915-1932 . PubMed
  187. Shen S, et al. 2018. Pain Med. 19:686. PubMed
  188. Ushijima M, et al. 2018. Front Immunol. 9:243. PubMed
  189. Schloss MJ, et al. 2022. Nat Immunol. 23:605. PubMed
  190. Li Q, et al. 2022. Cell Rep. 40:111308. PubMed
  191. Jong RM, et al. 2022. J Immunol. 208:407. PubMed
  192. Correa S, et al. 2020. ACS Nano. 14:2224. PubMed
  193. Gonalves S, et al. 2021. Cell Reports. 34(11):108860. PubMed
  194. Reboldi A, et al. 2016. Sci Transl Med. 352: aaf4822. PubMed
  195. Gazit R, et al. 2014. J Exp Med. 211:1315. PubMed
  196. Baptista AP et al. 2019. Immunity. 50(5):1188-1201 . PubMed
  197. Kunimura K, et al. 2020. Cell Reports. 29(9):2823-2834.e7.. PubMed
  198. Bedi B, et al. 2012. Proc Natl Acad Sci U S A. 109:275. PubMed
  199. Xu ZH, et al. 2021. Mediators Inflamm. 2021:8856326. PubMed
  200. Lutzmann M, et al. 2019. Cell Rep. 28:2851. PubMed
  201. Periasamy S, et al. 2017. Nat Commun. 8:15564. PubMed
  202. Lechner AJ et al. 2017. Cell stem cell. 21(1):120-134 . PubMed
  203. Shu T, et al. 2022. Eur Respir J. Online ahead of print. PubMed
  204. Al-Rifai R, et al. 2022. Nat Commun. 13:6592. PubMed
  205. Jazowiecka-Rakus J, et al. 2021. Cancers (Basel). 13:. PubMed
  206. Liang W, et al. 2020. Nat Commun. 4.563888889. PubMed
  207. Ma C, et al. 2018. Science. 360:eaan5931. PubMed
  208. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  209. Mathur S, et al. 2021. JCI Insight. 6:. PubMed
  210. Ohyagi M, et al. 2021. Nat Commun. 12:7344. PubMed
  211. Yan X, et al. 2022. Int J Biol Sci. 18:585. PubMed
  212. Helm M, et al. 2022. Life (Basel). 12:. PubMed
  213. Tu X, et al. 2022. Nat Commun. 13:6977. PubMed
  214. Schmidt D, et al. 2016. PLoS One. 11: 0159059. PubMed
  215. He C, et al. 2020. Clin Transl Med. 10:e39. PubMed
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RRID
AB_312663 (BioLegend Cat. No. 100206)
AB_312662 (BioLegend Cat. No. 100205)

Antigen Details

Structure
Ig superfamily, CD3/TCR, 20 kD
Distribution

Thymocytes (differentiation dependent), mature T cells, NK-T cells

Function
Antigen recognition, TCR signal transduction, T cell activation
Ligand/Receptor
Peptide antigen/MHC-complex
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Davis MM. 1990. Annu. Rev. Biochem. 59:475.
3. Weiss A, et al. 1994. Cell 76:263.

Gene ID
12502 View all products for this Gene ID
UniProt
View information about CD3 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.

Other Formats

View All CD3 Reagents Request Custom Conjugation
Description Clone Applications
Brilliant Violet 711™ anti-mouse CD3 17A2 FC
Biotin anti-mouse CD3 17A2 FC,IHC-F
PE/Dazzle™ 594 anti-mouse CD3 17A2 FC
APC/Fire™ 750 anti-mouse CD3 17A2 FC
Brilliant Violet 750™ anti-mouse CD3 17A2 FC
TotalSeq™-A0182 anti-mouse CD3 17A2 PG
TotalSeq™-B0182 anti-mouse CD3 17A2 PG
Spark Blue™ 550 anti-mouse CD3 17A2 FC
Spark NIR™ 685 anti-mouse CD3 17A2 FC
TotalSeq™-C0182 anti-mouse CD3 17A2 PG
APC/Fire™ 810 anti-mouse CD3 17A2 FC
PE/Fire™ 640 anti-mouse CD3 17A2 FC
Spark YG™ 570 anti-mouse CD3 17A2 IHC-F
PE/Fire™ 700 anti-mouse CD3 17A2 FC
FITC anti-mouse CD3 17A2 FC
PE anti-mouse CD3 17A2 FC
Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Alexa Fluor® 647 anti-mouse CD3 17A2 FC,IHC-F,3D IHC,SB
Test 17A2 5 17A2
Alexa Fluor® 488 anti-mouse CD3 17A2 FC,IHC-F,3D IHC
Pacific Blue™ anti-mouse CD3 17A2 FC
Alexa Fluor® 700 anti-mouse CD3 17A2 FC
PerCP/Cyanine5.5 anti-mouse CD3 17A2 FC
PE/Cyanine7 anti-mouse CD3 17A2 FC
APC/Cyanine7 anti-mouse CD3 17A2 FC
Brilliant Violet 421™ anti-mouse CD3 17A2 FC,ICC
Brilliant Violet 570™ anti-mouse CD3 17A2 FC
Brilliant Violet 650™ anti-mouse CD3 17A2 FC
Brilliant Violet 785™ anti-mouse CD3 17A2 FC
Brilliant Violet 510™ anti-mouse CD3 17A2 FC
APC anti-mouse CD3 17A2 FC
Ultra-LEAF™ Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Brilliant Violet 605™ anti-mouse CD3 17A2 FC
Alexa Fluor® 594 anti-mouse CD3 17A2 IHC-F,FC,3D IHC,SB
PE/Cyanine5 anti-mouse CD3 17A2 FC
Spark Blue™ 574 anti-mouse CD3 Antibody 17A2 FC
Spark Violet™ 423 anti-mouse CD3 17A2 FC
PE/Fire™ 810 anti-mouse CD3 17A2 FC
Spark Red™ 718 anti-mouse CD3 17A2 FC
Spark UV™ 387 anti-mouse CD3 17A2 FC
PerCP/Fire™ 780 anti-mouse CD3 Antibody 17A2 FC
PerCP anti-mouse CD3 Antibody 17A2 FC
Spark YG™ 581 anti-mouse CD3 (Flexi-Fluor™) 17A2 FC
Spark YG™ 593 anti-mouse CD3 (Flexi-Fluor™) Antibody 17A2 FC
Spark PLUS B488™ anti-mouse CD3 17A2 FC
Go To Top Version: 1    Revision Date: 11-30-2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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