Loading...

APC anti-mouse CD3 Antibody APC anti-mouse CD3 Antibody

Pricing & Availability
Clone
17A2 (See other available formats)
Regulatory Status
RUO
Other Names
T cell antigen receptor complex, T3
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
17A2_APC_073012
C57BL/6 mouse splenocytes were stained with CD3 (clone 17A2) APC (filled histogram) or rat IgG2b, κ isotype control (open histogram).
  • 17A2_APC_073012
    C57BL/6 mouse splenocytes were stained with CD3 (clone 17A2) APC (filled histogram) or rat IgG2b, κ isotype control (open histogram).
Compare all formats See APC spectral data
Cat # Size Price Quantity Check Availability Save
100235 25 µg SEK278
Check Availability


Need larger quantities of this item?
Request Bulk Quote
100236 100 µg SEK647
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
γδTCR-positive T-T hybridoma D1
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported application (for relevant formats) include: spatial biology (IBEX)1,2.

Application References
  1. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  2. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Koyama M, et al. 2015. J Exp Med. 212: 1303 - 1321. PubMed
  2. Morse M, et al. 2016. Lupus. 25: 81 - 87. PubMed
  3. Calabrese DR, et al. 2020. J Clin Invest. . PubMed
  4. Bergmann CA, et al. 2022. Cells. 11:. PubMed
  5. Akhtar MN, et al. 2022. MBio. 13:e0330921. PubMed
  6. Balakrishnan PB, et al. 2022. Nano Res. 15:2300. PubMed
  7. Shi X, et al. 2022. Proc Natl Acad Sci U S A. 119:e2208506119. PubMed
  8. Ho HM, et al. 2022. Pharmaceutics. 14:. PubMed
  9. Sparbier CE, et al. 2023. Nat Cell Biol. 25:258. PubMed
  10. Pan Y, et al. 2023. Adv Sci (Weinh). 10:e2206792. PubMed
  11. Wang X, et al. 2023. J Immunother Cancer. 11:. PubMed
  12. Liu N, et al. 2023. Cell Death Dis. 14:170. PubMed
  13. Gupta T, et al. 2023. Front Immunol. 14:1044703. PubMed
  14. Mabire M, et al. 2023. Nat Commun. 14:1830. PubMed
  15. Fu S, et al. 2023. Nat Commun. 14:2248. PubMed
  16. Li T, et al. 2023. Nat Commun. 14:2498. PubMed
  17. Zhang Z, et al. 2023. Aging Dis. 14:966. PubMed
  18. Bhaskar A, et al. 2023. iScience. 26:106644. PubMed
  19. Changsheng H, et al. 2023. Sci Adv. 9:eade4186. PubMed
  20. Cansever D, et al. 2023. Nat Immunol. . PubMed
  21. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  22. Liu J, et al. 2019. Immunity. 50:600. PubMed
  23. Rivas MA, et al. 2021. Nat Immunol. 22:240. PubMed
  24. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  25. Pani F, et al. 2021. Endocrinology. 162:. PubMed
  26. Hilfenhaus G, et al. 2021. Cancer Res. 81:619. PubMed
  27. Denny L, et al. 2021. Clin Transl Immunology. 10:e1234. PubMed
  28. Ramos SA, et al. 2022. J Allergy Clin Immunol. 149:767. PubMed
  29. Zhou Y, et al. 2021. Methods Mol Biol. 2388:35. PubMed
  30. Sugiura A, et al. 2022. Immunity. 55:65. PubMed
  31. Alam A, et al. 2022. Cancer Cell. 40:153. PubMed
  32. Cautivo KM, et al. 2022. Immunity. 55:254. PubMed
  33. Qi X, et al. 2022. FASEB J. 36:e22250. PubMed
  34. van Dierendonck XAMH, et al. 2022. Proc Natl Acad Sci U S A. 119:e2114739119. PubMed
  35. Corral D, et al. 2022. Cell Rep. 39:110715. PubMed
  36. Tu J, et al. 2022. Cancer Sci. 113:2496. PubMed
  37. Dolfi B, et al. 2022. Cell Rep. 39:110949. PubMed
  38. Du M, et al. 2022. Cancer Sci. 113:2974. PubMed
  39. Tessaro FHG, et al. 2022. Cell Rep. 39:110977. PubMed
  40. Grégoire C, et al. 2022. Immunity. 55:1216. PubMed
  41. Zhu J, et al. 2022. Research (Wash D C). 2022:9816272. PubMed
  42. Zhang Z, et al. 2022. Integr Cancer Ther. 21:15347354221138534. PubMed
  43. Miró L, et al. 2022. Cancers (Basel). 14: . PubMed
  44. An HW, et al. 2022. Cell Rep. 41:111878. PubMed
  45. Jin SM, et al. 2023. Nat Nanotechnol. :. PubMed
  46. Lin J, et al. 2023. Nat Commun. 14:224. PubMed
  47. Kang J, et al. 2023. JCI Insight. 8: . PubMed
  48. Chen Y, et al. 2023. Stem Cells Int. 2023:7482546. PubMed
  49. Li X, et al. 2022. Cell. 185:1709. PubMed
  50. Naito Y, et al. 2019. American Journal of Physiology-Renal Physiology. 318(1):F238-F247. PubMed
  51. Yang H, et al. 2019. Mol Metab. 23:24. PubMed
  52. Gabriely G, et al. 2021. iScience. 24:103347. PubMed
  53. Delvecchio FR, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:1543. PubMed
  54. Kim D, et al. 2021. Nanomicro Lett. 13:31. PubMed
  55. Sano T, et al. 2021. Cell Reports. 36:109608. PubMed
  56. Wilson RP, et al. 2019. PLoS Pathog. 15:e1007745. PubMed
  57. Yu VWC et al. 2016. Cell. 167(5):1310-1322 . PubMed
  58. Huang X, et al. 2019. Cancer Immunol Res. 1.388888889. PubMed
  59. Gupta SS, et al. 2019. Cell Rep. 29:1862. PubMed
  60. Fu X, et al. 2020. J Immunol. 205:2066. PubMed
  61. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  62. Baram T, et al. 2021. Cells. 10:. PubMed
  63. Luo R, et al. 2021. Theranostics. 11:117. PubMed
  64. Pessoa Rodrigues C, et al. 2021. Sci Adv. 7:. PubMed
  65. Zhang S, et al. 2022. Cell Death Dis. 13:844. PubMed
  66. Forte E, et al. 2020. J Cell Mol Med. . PubMed
  67. Haque M, et al. 2021. STAR Protoc. 2:100264. PubMed
  68. Gruber T, et al. 2020. JCI Insight. 5:00. PubMed
  69. Yamamoto R et al. 2018. Cell stem cell. 22(4):600-607 . PubMed
  70. Greenberg J, et al. 2022. JCI Insight. Online ahead of print. PubMed
  71. Kremenovic M, et al. 2022. J Immunother Cancer. 10:. PubMed
  72. Peng Z, et al. 2021. STAR Protocols. 2(2):100595. PubMed
  73. Wang X, et al. 2021. Front Cell Dev Biol. 632805:9. PubMed
  74. Swidergall M, et al. 2019. Cell Rep. 28:423. PubMed
  75. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  76. Fujino T, et al. 2021. Nat Commun. 12:1826. PubMed
  77. Shi S, et al. 2020. Clin Cancer Res. 26:5990. PubMed
  78. Almutairi F, et al. 2021. Front Immunol. 12:772288. PubMed
  79. Magod P, et al. 2021. Cell Reports. 36(5):109480. PubMed
  80. Yoshimi A, et al. 2019. Nature. 574:273. PubMed
  81. Thomas S, et al. 2019. J Immunother Cancer. 7:214. PubMed
  82. Uchimura T et al. 2018. Immunity. 49(6):1049-1061 . PubMed
  83. Zhang X, et al. 2022. Pharmaceutics. 14:. PubMed
  84. Tang D, et al. 2020. Br J Haematol. 191:906. PubMed
  85. van Elsas MJ, et al. 2022. Int J Mol Sci. 23:. PubMed
  86. Francian A, et al. 2021. J Drug Target. 29:754. PubMed
  87. Antunes KH, et al. 2022. Front Immunol. 13:867022. PubMed
  88. Mastandrea I, et al. 2022. STAR Protoc. 3:101106. PubMed
  89. Wu G, et al. 2020. Br J Pharmacol. 177:5063. PubMed
  90. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  91. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  92. Zhang F, et al. 2019. Immunity. 50:738. PubMed
  93. Liu H, et al. 2020. Cancer Cell. 37(3):324-339. PubMed
  94. Li X, et al. 2020. Mol Ther. 28:2430. PubMed
  95. Guo W, et al. 2022. J Immunother Cancer. 10:. PubMed
  96. Ren HZ, et al. 2022. J Clin Transl Hepatol. 10:1138. PubMed
  97. Utley A, et al. 2020. Cell Rep. 31:107815. PubMed
  98. Utz B, et al. 2020. Sci Rep. 10:18733. PubMed
  99. Hiramoto T, et al. 2018. Mol Ther. 26:1255. PubMed
  100. Yu VWC, et al. 2017. Cell. 168:944. PubMed
  101. Wang GZ, et al. 2019. Nat Commun. 10:1125. PubMed
  102. Chen X et al. 2017. Cell stem cell. 21(6):747-760 . PubMed
  103. Wang W, et al. 2022. Aging Cell. 21:e13630. PubMed
  104. Xie Z, et al. 2020. Light Sci Appl. 0.486805556. PubMed
  105. Court AC, et al. 2020. EMBO Rep. 21:e48052. PubMed
  106. Venturutti L, et al. 2020. Cell. 182(2):297-316.e27. PubMed
  107. Zhang W, et al. 2019. Oncol Lett. 17:815. PubMed
  108. Schadt L, et al. 2020. Cell Reports. 29(5):1236-1248.e7.. PubMed
  109. Hu Q, et al. 2018. Nat Biomed Eng. 0.660416667. PubMed
  110. Suryawanshi RK, et al. 2021. Nat Commun. 12:6020. PubMed
  111. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  112. Chauveau A, et al. 2020. Immunity. 52:794. PubMed
  113. Haikala HM, et al. 2019. Nat Commun. 10:620. PubMed
  114. Zhao X, et al. 2022. Nat Protoc. 17:2240. PubMed
  115. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  116. Reinfeld BI, et al. 2021. Nature. 593:282. PubMed
  117. Kruta M, et al. 2021. Cell Stem Cell. :. PubMed
  118. Liu Y, et al. 2017. Oncogene. 10.1038/onc.2017.209. PubMed
  119. Hu J, et al. 2019. Mol Ther Nucleic Acids. 16:650. PubMed
  120. Burr ML, et al. 2019. Cancer Cell. 36:385. PubMed
  121. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  122. Huang Z, et al. 2021. Nat Commun. 12:145. PubMed
  123. Zhu Y, et al. 2021. EMBO J. 40:e105320. PubMed
  124. Wang Y, et al. 2021. Front Microbiol. 12:701566. PubMed
  125. Zheng D, et al. 2022. Acta Pharm Sin B. 12:2740. PubMed
  126. Tomala J, et al. 2020. Methods Mol Biol. 2111:101. PubMed
  127. Wen M, et al. 2022. JCI Insight. Online ahead of print. PubMed
  128. Stirling ER, et al. 2022. J Immunother Cancer. 10:. PubMed
  129. Li H, et al. 2021. Adv Sci (Weinh). 2001596:8. PubMed
  130. Tomay F, et al. 2019. J Transl Med. 17:237. PubMed
  131. Xiong W, et al. 2022. Adv Sci (Weinh). 9:e2103029. PubMed
  132. Xiao L, et al. 2021. Clin Cancer Res. 27:4338. PubMed
  133. Huang L, et al. 2021. Breast Cancer Res Treat. Online ahead of print. PubMed
  134. Han F, et al. 2020. Invest Ophthalmol Vis Sci. 61:24. PubMed
  135. Wang X, et al. 2020. Nat Commun. 4.505555556. PubMed
  136. Johnson DC, et al. 2020. Cell Death Dis. 0.894444444. PubMed
  137. Evgin L, et al. 2020. Nat Commun. 2.671527778. PubMed
  138. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  139. Xu P, et al. 2020. Cancer Immunol Res. 8:1193. PubMed
  140. Xi‐Zhi J Guo et al. 2018. Immunity. 49(3):531-544 . PubMed
  141. Subramanian K, et al. 2019. Nat Microbiol. 4:62. PubMed
  142. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  143. Chen C, et al. 2021. J Virol. 95:e0082921. PubMed
  144. Martinez-Turtos A, et al. 2022. Oncoimmunology. 11:2116844. PubMed
  145. Zeng Q, et al. 2022. iScience. 25:105151. PubMed
  146. Adnan-Awad S, et al. 2020. Leukemia. . PubMed
  147. Liu Y, et al. 2020. Oncol Lett. 2369:20. PubMed
  148. Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
  149. Cianciaruso C, et al. 2020. Cell Reports. 27(10):3062-3080.e11.. PubMed
  150. Zhang J, et al. 2018. Nature. 553:91. PubMed
  151. Pascual-Pasto G, et al. 2022. J Immunother Cancer. 10:. PubMed
  152. Li Z, et al. 2022. Nat Commun. 13:6321. PubMed
  153. Olivo Pimentel V, et al. 2021. J Immunother Cancer. 9:. PubMed
  154. Li M, et al. 2021. Cancers (Basel). 13:. PubMed
  155. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
  156. Yu M, et al. 2021. Molecular Cell. 81(6):1216-1230.e9. PubMed
  157. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  158. Nechama M, et al. 2018. Nat Commun. 9:1603. PubMed
  159. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  160. Siddique SM, et al. 2019. Sci Rep. 9:13977. PubMed
  161. Kim S, et al. 2020. Autophagy. :1. PubMed
  162. Lazarian G, et al. 2021. Cancer Cell. 39(3):380-393.e8. PubMed
  163. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  164. Olson CA, et al. 2021. Cell Host Microbe. 29:1378. PubMed
  165. Li K, et al. 2020. Nat Commun. 4.844444444. PubMed
  166. Hering L, et al. 2020. Front Immunol. 1.747222222. PubMed
  167. Yoshida S, et al. 2022. PLoS One. 17:e0264317. PubMed
  168. Zhong C, et al. 2021. J Virol. 95:e0092521. PubMed
  169. Kelley WJ, et al. 2022. JCI Insight. 7: . PubMed
  170. Wang Y, et al. 2021. Cell Reports. 36(6):109516. PubMed
  171. Hidalgo San Jose L, et al. 2020. Cell Rep. 30:69. PubMed
  172. Hao L, et al. 2021. Br J Pharmacol. 178:4726. PubMed
  173. Lau P, et al. 2022. Cell Mol Immunol. :. PubMed
  174. Arora S, et al. 2021. Med (N Y). 2:938. PubMed
  175. Li H, et al. 2022. iScience. 25:104481. PubMed
  176. Gardenier J, et al. 2017. Nat Commun. 8:14345. PubMed
  177. Heyde A, et al. 2021. Cell. 184(5):1348-1361.e22. PubMed
  178. Zeng A, et al. 2020. Oncol Rep. . PubMed
  179. Das A, et al. 2020. J Bone Miner Res. 36:199. PubMed
  180. Agelidis A, et al. 2017. Cell Rep. 10.1016/j.celrep.2017.06.041. PubMed
  181. Sartorius R, et al. 2018. Front Immunol. 1.413888889. PubMed
  182. Hong Y, et al. 2019. J Extracell Vesicles. 8:1670893. PubMed
  183. Lightman SM, et al. 2020. Cell Reports. 1.086805556. PubMed
  184. Kujur W, et al. 2020. PLoS Pathog. 16:e1009132. PubMed
  185. Wang X, et al. 2021. Sci Transl Med. 13:. PubMed
  186. Rappe JCF, et al. 2021. J Exp Med. 218:. PubMed
  187. Lee A, et al. 2022. Nat Commun. 13:549. PubMed
  188. Tripathi D, et al. 2016. Nat Commun. 7:13896. PubMed
  189. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  190. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  191. Akhtar MN, et al. 2020. PLoS Pathog. 16:e1009136. PubMed
  192. Zhang J, et al. 2021. Stem Cell Res Ther. 12:579. PubMed
  193. Chang MH, et al. 2021. Cell Rep. 37:109902. PubMed
  194. Xie Z, et al. 2020. Light Sci Appl. 9:161. PubMed
  195. Lake CM, et al. 2021. Cell Death Dis. 12:400. PubMed
  196. Koyama M, et al. 2015. J Exp Med. 212: 1303 - 1321. PubMed
  197. Morse M, et al. 2016. Lupus. 25: 81 - 87. PubMed
  198. Calabrese DR, et al. 2020. J Clin Invest. . PubMed
  199. Bergmann CA, et al. 2022. Cells. 11:. PubMed
  200. Akhtar MN, et al. 2022. MBio. 13:e0330921. PubMed
  201. Balakrishnan PB, et al. 2022. Nano Res. 15:2300. PubMed
  202. Shi X, et al. 2022. Proc Natl Acad Sci U S A. 119:e2208506119. PubMed
  203. Ho HM, et al. 2022. Pharmaceutics. 14:. PubMed
  204. Sparbier CE, et al. 2023. Nat Cell Biol. 25:258. PubMed
  205. Pan Y, et al. 2023. Adv Sci (Weinh). 10:e2206792. PubMed
  206. Wang X, et al. 2023. J Immunother Cancer. 11:. PubMed
  207. Liu N, et al. 2023. Cell Death Dis. 14:170. PubMed
  208. Gupta T, et al. 2023. Front Immunol. 14:1044703. PubMed
  209. Mabire M, et al. 2023. Nat Commun. 14:1830. PubMed
  210. Fu S, et al. 2023. Nat Commun. 14:2248. PubMed
  211. Li T, et al. 2023. Nat Commun. 14:2498. PubMed
  212. Zhang Z, et al. 2023. Aging Dis. 14:966. PubMed
  213. Bhaskar A, et al. 2023. iScience. 26:106644. PubMed
  214. Changsheng H, et al. 2023. Sci Adv. 9:eade4186. PubMed
  215. Cansever D, et al. 2023. Nat Immunol. . PubMed
  216. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  217. Liu J, et al. 2019. Immunity. 50:600. PubMed
  218. Rivas MA, et al. 2021. Nat Immunol. 22:240. PubMed
  219. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  220. Pani F, et al. 2021. Endocrinology. 162:. PubMed
  221. Hilfenhaus G, et al. 2021. Cancer Res. 81:619. PubMed
  222. Denny L, et al. 2021. Clin Transl Immunology. 10:e1234. PubMed
  223. Ramos SA, et al. 2022. J Allergy Clin Immunol. 149:767. PubMed
  224. Zhou Y, et al. 2021. Methods Mol Biol. 2388:35. PubMed
  225. Sugiura A, et al. 2022. Immunity. 55:65. PubMed
  226. Alam A, et al. 2022. Cancer Cell. 40:153. PubMed
  227. Cautivo KM, et al. 2022. Immunity. 55:254. PubMed
  228. Qi X, et al. 2022. FASEB J. 36:e22250. PubMed
  229. van Dierendonck XAMH, et al. 2022. Proc Natl Acad Sci U S A. 119:e2114739119. PubMed
  230. Corral D, et al. 2022. Cell Rep. 39:110715. PubMed
  231. Tu J, et al. 2022. Cancer Sci. 113:2496. PubMed
  232. Dolfi B, et al. 2022. Cell Rep. 39:110949. PubMed
  233. Du M, et al. 2022. Cancer Sci. 113:2974. PubMed
  234. Tessaro FHG, et al. 2022. Cell Rep. 39:110977. PubMed
  235. Grégoire C, et al. 2022. Immunity. 55:1216. PubMed
  236. Zhu J, et al. 2022. Research (Wash D C). 2022:9816272. PubMed
  237. Zhang Z, et al. 2022. Integr Cancer Ther. 21:15347354221138534. PubMed
  238. Miró L, et al. 2022. Cancers (Basel). 14: . PubMed
  239. An HW, et al. 2022. Cell Rep. 41:111878. PubMed
  240. Jin SM, et al. 2023. Nat Nanotechnol. :. PubMed
  241. Lin J, et al. 2023. Nat Commun. 14:224. PubMed
  242. Kang J, et al. 2023. JCI Insight. 8: . PubMed
  243. Chen Y, et al. 2023. Stem Cells Int. 2023:7482546. PubMed
  244. Li X, et al. 2022. Cell. 185:1709. PubMed
  245. Naito Y, et al. 2019. American Journal of Physiology-Renal Physiology. 318(1):F238-F247. PubMed
  246. Yang H, et al. 2019. Mol Metab. 23:24. PubMed
  247. Gabriely G, et al. 2021. iScience. 24:103347. PubMed
  248. Delvecchio FR, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:1543. PubMed
  249. Kim D, et al. 2021. Nanomicro Lett. 13:31. PubMed
  250. Sano T, et al. 2021. Cell Reports. 36:109608. PubMed
  251. Wilson RP, et al. 2019. PLoS Pathog. 15:e1007745. PubMed
  252. Yu VWC et al. 2016. Cell. 167(5):1310-1322 . PubMed
  253. Huang X, et al. 2019. Cancer Immunol Res. 1.388888889. PubMed
  254. Gupta SS, et al. 2019. Cell Rep. 29:1862. PubMed
  255. Fu X, et al. 2020. J Immunol. 205:2066. PubMed
  256. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  257. Baram T, et al. 2021. Cells. 10:. PubMed
  258. Luo R, et al. 2021. Theranostics. 11:117. PubMed
  259. Pessoa Rodrigues C, et al. 2021. Sci Adv. 7:. PubMed
  260. Zhang S, et al. 2022. Cell Death Dis. 13:844. PubMed
  261. Forte E, et al. 2020. J Cell Mol Med. . PubMed
  262. Haque M, et al. 2021. STAR Protoc. 2:100264. PubMed
  263. Gruber T, et al. 2020. JCI Insight. 5:00. PubMed
  264. Yamamoto R et al. 2018. Cell stem cell. 22(4):600-607 . PubMed
  265. Greenberg J, et al. 2022. JCI Insight. Online ahead of print. PubMed
  266. Kremenovic M, et al. 2022. J Immunother Cancer. 10:. PubMed
  267. Peng Z, et al. 2021. STAR Protocols. 2(2):100595. PubMed
  268. Wang X, et al. 2021. Front Cell Dev Biol. 632805:9. PubMed
  269. Swidergall M, et al. 2019. Cell Rep. 28:423. PubMed
  270. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  271. Fujino T, et al. 2021. Nat Commun. 12:1826. PubMed
  272. Shi S, et al. 2020. Clin Cancer Res. 26:5990. PubMed
  273. Almutairi F, et al. 2021. Front Immunol. 12:772288. PubMed
  274. Magod P, et al. 2021. Cell Reports. 36(5):109480. PubMed
  275. Yoshimi A, et al. 2019. Nature. 574:273. PubMed
  276. Thomas S, et al. 2019. J Immunother Cancer. 7:214. PubMed
  277. Uchimura T et al. 2018. Immunity. 49(6):1049-1061 . PubMed
  278. Zhang X, et al. 2022. Pharmaceutics. 14:. PubMed
  279. Tang D, et al. 2020. Br J Haematol. 191:906. PubMed
  280. van Elsas MJ, et al. 2022. Int J Mol Sci. 23:. PubMed
  281. Francian A, et al. 2021. J Drug Target. 29:754. PubMed
  282. Antunes KH, et al. 2022. Front Immunol. 13:867022. PubMed
  283. Mastandrea I, et al. 2022. STAR Protoc. 3:101106. PubMed
  284. Wu G, et al. 2020. Br J Pharmacol. 177:5063. PubMed
  285. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  286. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  287. Zhang F, et al. 2019. Immunity. 50:738. PubMed
  288. Liu H, et al. 2020. Cancer Cell. 37(3):324-339. PubMed
  289. Li X, et al. 2020. Mol Ther. 28:2430. PubMed
  290. Guo W, et al. 2022. J Immunother Cancer. 10:. PubMed
  291. Ren HZ, et al. 2022. J Clin Transl Hepatol. 10:1138. PubMed
  292. Utley A, et al. 2020. Cell Rep. 31:107815. PubMed
  293. Utz B, et al. 2020. Sci Rep. 10:18733. PubMed
  294. Hiramoto T, et al. 2018. Mol Ther. 26:1255. PubMed
  295. Yu VWC, et al. 2017. Cell. 168:944. PubMed
  296. Wang GZ, et al. 2019. Nat Commun. 10:1125. PubMed
  297. Chen X et al. 2017. Cell stem cell. 21(6):747-760 . PubMed
  298. Wang W, et al. 2022. Aging Cell. 21:e13630. PubMed
  299. Xie Z, et al. 2020. Light Sci Appl. 0.486805556. PubMed
  300. Court AC, et al. 2020. EMBO Rep. 21:e48052. PubMed
  301. Venturutti L, et al. 2020. Cell. 182(2):297-316.e27. PubMed
  302. Zhang W, et al. 2019. Oncol Lett. 17:815. PubMed
  303. Schadt L, et al. 2020. Cell Reports. 29(5):1236-1248.e7.. PubMed
  304. Hu Q, et al. 2018. Nat Biomed Eng. 0.660416667. PubMed
  305. Suryawanshi RK, et al. 2021. Nat Commun. 12:6020. PubMed
  306. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  307. Chauveau A, et al. 2020. Immunity. 52:794. PubMed
  308. Haikala HM, et al. 2019. Nat Commun. 10:620. PubMed
  309. Zhao X, et al. 2022. Nat Protoc. 17:2240. PubMed
  310. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  311. Reinfeld BI, et al. 2021. Nature. 593:282. PubMed
  312. Kruta M, et al. 2021. Cell Stem Cell. :. PubMed
  313. Liu Y, et al. 2017. Oncogene. 10.1038/onc.2017.209. PubMed
  314. Hu J, et al. 2019. Mol Ther Nucleic Acids. 16:650. PubMed
  315. Burr ML, et al. 2019. Cancer Cell. 36:385. PubMed
  316. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  317. Huang Z, et al. 2021. Nat Commun. 12:145. PubMed
  318. Zhu Y, et al. 2021. EMBO J. 40:e105320. PubMed
  319. Wang Y, et al. 2021. Front Microbiol. 12:701566. PubMed
  320. Zheng D, et al. 2022. Acta Pharm Sin B. 12:2740. PubMed
  321. Tomala J, et al. 2020. Methods Mol Biol. 2111:101. PubMed
  322. Wen M, et al. 2022. JCI Insight. Online ahead of print. PubMed
  323. Stirling ER, et al. 2022. J Immunother Cancer. 10:. PubMed
  324. Li H, et al. 2021. Adv Sci (Weinh). 2001596:8. PubMed
  325. Tomay F, et al. 2019. J Transl Med. 17:237. PubMed
  326. Xiong W, et al. 2022. Adv Sci (Weinh). 9:e2103029. PubMed
  327. Xiao L, et al. 2021. Clin Cancer Res. 27:4338. PubMed
  328. Huang L, et al. 2021. Breast Cancer Res Treat. Online ahead of print. PubMed
  329. Han F, et al. 2020. Invest Ophthalmol Vis Sci. 61:24. PubMed
  330. Wang X, et al. 2020. Nat Commun. 4.505555556. PubMed
  331. Johnson DC, et al. 2020. Cell Death Dis. 0.894444444. PubMed
  332. Evgin L, et al. 2020. Nat Commun. 2.671527778. PubMed
  333. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  334. Xu P, et al. 2020. Cancer Immunol Res. 8:1193. PubMed
  335. Xi‐Zhi J Guo et al. 2018. Immunity. 49(3):531-544 . PubMed
  336. Subramanian K, et al. 2019. Nat Microbiol. 4:62. PubMed
  337. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  338. Chen C, et al. 2021. J Virol. 95:e0082921. PubMed
  339. Martinez-Turtos A, et al. 2022. Oncoimmunology. 11:2116844. PubMed
  340. Zeng Q, et al. 2022. iScience. 25:105151. PubMed
  341. Adnan-Awad S, et al. 2020. Leukemia. . PubMed
  342. Liu Y, et al. 2020. Oncol Lett. 2369:20. PubMed
  343. Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
  344. Cianciaruso C, et al. 2020. Cell Reports. 27(10):3062-3080.e11.. PubMed
  345. Zhang J, et al. 2018. Nature. 553:91. PubMed
  346. Pascual-Pasto G, et al. 2022. J Immunother Cancer. 10:. PubMed
  347. Li Z, et al. 2022. Nat Commun. 13:6321. PubMed
  348. Olivo Pimentel V, et al. 2021. J Immunother Cancer. 9:. PubMed
  349. Li M, et al. 2021. Cancers (Basel). 13:. PubMed
  350. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
  351. Yu M, et al. 2021. Molecular Cell. 81(6):1216-1230.e9. PubMed
  352. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  353. Nechama M, et al. 2018. Nat Commun. 9:1603. PubMed
  354. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  355. Siddique SM, et al. 2019. Sci Rep. 9:13977. PubMed
  356. Kim S, et al. 2020. Autophagy. :1. PubMed
  357. Lazarian G, et al. 2021. Cancer Cell. 39(3):380-393.e8. PubMed
  358. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  359. Olson CA, et al. 2021. Cell Host Microbe. 29:1378. PubMed
  360. Li K, et al. 2020. Nat Commun. 4.844444444. PubMed
  361. Hering L, et al. 2020. Front Immunol. 1.747222222. PubMed
  362. Yoshida S, et al. 2022. PLoS One. 17:e0264317. PubMed
  363. Zhong C, et al. 2021. J Virol. 95:e0092521. PubMed
  364. Kelley WJ, et al. 2022. JCI Insight. 7: . PubMed
  365. Wang Y, et al. 2021. Cell Reports. 36(6):109516. PubMed
  366. Hidalgo San Jose L, et al. 2020. Cell Rep. 30:69. PubMed
  367. Hao L, et al. 2021. Br J Pharmacol. 178:4726. PubMed
  368. Lau P, et al. 2022. Cell Mol Immunol. :. PubMed
  369. Arora S, et al. 2021. Med (N Y). 2:938. PubMed
  370. Li H, et al. 2022. iScience. 25:104481. PubMed
  371. Gardenier J, et al. 2017. Nat Commun. 8:14345. PubMed
  372. Heyde A, et al. 2021. Cell. 184(5):1348-1361.e22. PubMed
  373. Zeng A, et al. 2020. Oncol Rep. . PubMed
  374. Das A, et al. 2020. J Bone Miner Res. 36:199. PubMed
  375. Agelidis A, et al. 2017. Cell Rep. 10.1016/j.celrep.2017.06.041. PubMed
  376. Sartorius R, et al. 2018. Front Immunol. 1.413888889. PubMed
  377. Hong Y, et al. 2019. J Extracell Vesicles. 8:1670893. PubMed
  378. Lightman SM, et al. 2020. Cell Reports. 1.086805556. PubMed
  379. Kujur W, et al. 2020. PLoS Pathog. 16:e1009132. PubMed
  380. Wang X, et al. 2021. Sci Transl Med. 13:. PubMed
  381. Rappe JCF, et al. 2021. J Exp Med. 218:. PubMed
  382. Lee A, et al. 2022. Nat Commun. 13:549. PubMed
  383. Tripathi D, et al. 2016. Nat Commun. 7:13896. PubMed
  384. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  385. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  386. Akhtar MN, et al. 2020. PLoS Pathog. 16:e1009136. PubMed
  387. Zhang J, et al. 2021. Stem Cell Res Ther. 12:579. PubMed
  388. Chang MH, et al. 2021. Cell Rep. 37:109902. PubMed
  389. Xie Z, et al. 2020. Light Sci Appl. 9:161. PubMed
  390. Lake CM, et al. 2021. Cell Death Dis. 12:400. PubMed
RRID
AB_2561455 (BioLegend Cat. No. 100235)
AB_2561456 (BioLegend Cat. No. 100236)

Antigen Details

Structure
Ig superfamily, CD3/TCR, 20 kD
Distribution

Thymocytes (differentiation dependent), mature T cells, NK-T cells

Function
Antigen recognition, TCR signal transduction, T cell activation
Ligand/Receptor
Peptide antigen/MHC-complex
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Davis MM. 1990. Annu. Rev. Biochem. 59:475.
3. Weiss A, et al. 1994. Cell 76:263.

Gene ID
12502 View all products for this Gene ID
UniProt
View information about CD3 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD3 Reagents Request Custom Conjugation
Description Clone Applications
Brilliant Violet 711™ anti-mouse CD3 17A2 FC
Biotin anti-mouse CD3 17A2 FC,IHC-F
PE/Dazzle™ 594 anti-mouse CD3 17A2 FC
APC/Fire™ 750 anti-mouse CD3 17A2 FC
Brilliant Violet 750™ anti-mouse CD3 17A2 FC
TotalSeq™-A0182 anti-mouse CD3 17A2 PG
TotalSeq™-B0182 anti-mouse CD3 17A2 PG
Spark Blue™ 550 anti-mouse CD3 17A2 FC
Spark NIR™ 685 anti-mouse CD3 17A2 FC
TotalSeq™-C0182 anti-mouse CD3 17A2 PG
APC/Fire™ 810 anti-mouse CD3 17A2 FC
PE/Fire™ 640 anti-mouse CD3 17A2 FC
Spark YG™ 570 anti-mouse CD3 17A2 IHC-F
PE/Fire™ 700 anti-mouse CD3 17A2 FC
Test 17A2 5 17A2
FITC anti-mouse CD3 17A2 FC
PE anti-mouse CD3 17A2 FC
Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Alexa Fluor® 647 anti-mouse CD3 17A2 FC,IHC-F,3D IHC,SB
Alexa Fluor® 488 anti-mouse CD3 17A2 FC,IHC-F,3D IHC
Pacific Blue™ anti-mouse CD3 17A2 FC
Alexa Fluor® 700 anti-mouse CD3 17A2 FC
PerCP/Cyanine5.5 anti-mouse CD3 17A2 FC
PE/Cyanine7 anti-mouse CD3 17A2 FC
APC/Cyanine7 anti-mouse CD3 17A2 FC
Brilliant Violet 421™ anti-mouse CD3 17A2 FC,ICC
Brilliant Violet 570™ anti-mouse CD3 17A2 FC
Brilliant Violet 650™ anti-mouse CD3 17A2 FC
Brilliant Violet 785™ anti-mouse CD3 17A2 FC
Brilliant Violet 510™ anti-mouse CD3 17A2 FC
APC anti-mouse CD3 17A2 FC
Ultra-LEAF™ Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Brilliant Violet 605™ anti-mouse CD3 17A2 FC
Alexa Fluor® 594 anti-mouse CD3 17A2 IHC-F,FC,3D IHC,SB
PE/Cyanine5 anti-mouse CD3 17A2 FC
Spark Blue™ 574 anti-mouse CD3 Antibody 17A2 FC
Spark Violet™ 423 anti-mouse CD3 17A2 FC
PE/Fire™ 810 anti-mouse CD3 17A2 FC
Spark Red™ 718 anti-mouse CD3 17A2 FC
Spark UV™ 387 anti-mouse CD3 17A2 FC
PerCP/Fire™ 780 anti-mouse CD3 Antibody 17A2 FC
PerCP anti-mouse CD3 Antibody 17A2 FC
Spark YG™ 581 anti-mouse CD3 (Flexi-Fluor™) 17A2 FC
Spark YG™ 593 anti-mouse CD3 (Flexi-Fluor™) Antibody 17A2 FC
Spark PLUS B488™ anti-mouse CD3 17A2 FC
Go To Top Version: 1    Revision Date: 11-30-2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

Pricing & Availability
Clone
17A2 (See other available formats)
Regulatory Status
RUO
Other Names
T cell antigen receptor complex, T3
Isotype
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
publications
17A2_APC_073012
C57BL/6 mouse splenocytes were stained with CD3 (clone 17A2) APC (filled histogram) or rat IgG2b, κ isotype control (open histogram).
  • 17A2_APC_073012
    C57BL/6 mouse splenocytes were stained with CD3 (clone 17A2) APC (filled histogram) or rat IgG2b, κ isotype control (open histogram).
Compare all formats See APC spectral data
Cat # Size Price Quantity Check Availability Save
100235 25 µg SEK278
Check Availability


Need larger quantities of this item?
Request Bulk Quote
100236 100 µg SEK647
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
γδTCR-positive T-T hybridoma D1
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported application (for relevant formats) include: spatial biology (IBEX)1,2.

Application References
  1. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  2. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Koyama M, et al. 2015. J Exp Med. 212: 1303 - 1321. PubMed
  2. Morse M, et al. 2016. Lupus. 25: 81 - 87. PubMed
  3. Calabrese DR, et al. 2020. J Clin Invest. . PubMed
  4. Bergmann CA, et al. 2022. Cells. 11:. PubMed
  5. Akhtar MN, et al. 2022. MBio. 13:e0330921. PubMed
  6. Balakrishnan PB, et al. 2022. Nano Res. 15:2300. PubMed
  7. Shi X, et al. 2022. Proc Natl Acad Sci U S A. 119:e2208506119. PubMed
  8. Ho HM, et al. 2022. Pharmaceutics. 14:. PubMed
  9. Sparbier CE, et al. 2023. Nat Cell Biol. 25:258. PubMed
  10. Pan Y, et al. 2023. Adv Sci (Weinh). 10:e2206792. PubMed
  11. Wang X, et al. 2023. J Immunother Cancer. 11:. PubMed
  12. Liu N, et al. 2023. Cell Death Dis. 14:170. PubMed
  13. Gupta T, et al. 2023. Front Immunol. 14:1044703. PubMed
  14. Mabire M, et al. 2023. Nat Commun. 14:1830. PubMed
  15. Fu S, et al. 2023. Nat Commun. 14:2248. PubMed
  16. Li T, et al. 2023. Nat Commun. 14:2498. PubMed
  17. Zhang Z, et al. 2023. Aging Dis. 14:966. PubMed
  18. Bhaskar A, et al. 2023. iScience. 26:106644. PubMed
  19. Changsheng H, et al. 2023. Sci Adv. 9:eade4186. PubMed
  20. Cansever D, et al. 2023. Nat Immunol. . PubMed
  21. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  22. Liu J, et al. 2019. Immunity. 50:600. PubMed
  23. Rivas MA, et al. 2021. Nat Immunol. 22:240. PubMed
  24. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  25. Pani F, et al. 2021. Endocrinology. 162:. PubMed
  26. Hilfenhaus G, et al. 2021. Cancer Res. 81:619. PubMed
  27. Denny L, et al. 2021. Clin Transl Immunology. 10:e1234. PubMed
  28. Ramos SA, et al. 2022. J Allergy Clin Immunol. 149:767. PubMed
  29. Zhou Y, et al. 2021. Methods Mol Biol. 2388:35. PubMed
  30. Sugiura A, et al. 2022. Immunity. 55:65. PubMed
  31. Alam A, et al. 2022. Cancer Cell. 40:153. PubMed
  32. Cautivo KM, et al. 2022. Immunity. 55:254. PubMed
  33. Qi X, et al. 2022. FASEB J. 36:e22250. PubMed
  34. van Dierendonck XAMH, et al. 2022. Proc Natl Acad Sci U S A. 119:e2114739119. PubMed
  35. Corral D, et al. 2022. Cell Rep. 39:110715. PubMed
  36. Tu J, et al. 2022. Cancer Sci. 113:2496. PubMed
  37. Dolfi B, et al. 2022. Cell Rep. 39:110949. PubMed
  38. Du M, et al. 2022. Cancer Sci. 113:2974. PubMed
  39. Tessaro FHG, et al. 2022. Cell Rep. 39:110977. PubMed
  40. Grégoire C, et al. 2022. Immunity. 55:1216. PubMed
  41. Zhu J, et al. 2022. Research (Wash D C). 2022:9816272. PubMed
  42. Zhang Z, et al. 2022. Integr Cancer Ther. 21:15347354221138534. PubMed
  43. Miró L, et al. 2022. Cancers (Basel). 14: . PubMed
  44. An HW, et al. 2022. Cell Rep. 41:111878. PubMed
  45. Jin SM, et al. 2023. Nat Nanotechnol. :. PubMed
  46. Lin J, et al. 2023. Nat Commun. 14:224. PubMed
  47. Kang J, et al. 2023. JCI Insight. 8: . PubMed
  48. Chen Y, et al. 2023. Stem Cells Int. 2023:7482546. PubMed
  49. Li X, et al. 2022. Cell. 185:1709. PubMed
  50. Naito Y, et al. 2019. American Journal of Physiology-Renal Physiology. 318(1):F238-F247. PubMed
  51. Yang H, et al. 2019. Mol Metab. 23:24. PubMed
  52. Gabriely G, et al. 2021. iScience. 24:103347. PubMed
  53. Delvecchio FR, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:1543. PubMed
  54. Kim D, et al. 2021. Nanomicro Lett. 13:31. PubMed
  55. Sano T, et al. 2021. Cell Reports. 36:109608. PubMed
  56. Wilson RP, et al. 2019. PLoS Pathog. 15:e1007745. PubMed
  57. Yu VWC et al. 2016. Cell. 167(5):1310-1322 . PubMed
  58. Huang X, et al. 2019. Cancer Immunol Res. 1.388888889. PubMed
  59. Gupta SS, et al. 2019. Cell Rep. 29:1862. PubMed
  60. Fu X, et al. 2020. J Immunol. 205:2066. PubMed
  61. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  62. Baram T, et al. 2021. Cells. 10:. PubMed
  63. Luo R, et al. 2021. Theranostics. 11:117. PubMed
  64. Pessoa Rodrigues C, et al. 2021. Sci Adv. 7:. PubMed
  65. Zhang S, et al. 2022. Cell Death Dis. 13:844. PubMed
  66. Forte E, et al. 2020. J Cell Mol Med. . PubMed
  67. Haque M, et al. 2021. STAR Protoc. 2:100264. PubMed
  68. Gruber T, et al. 2020. JCI Insight. 5:00. PubMed
  69. Yamamoto R et al. 2018. Cell stem cell. 22(4):600-607 . PubMed
  70. Greenberg J, et al. 2022. JCI Insight. Online ahead of print. PubMed
  71. Kremenovic M, et al. 2022. J Immunother Cancer. 10:. PubMed
  72. Peng Z, et al. 2021. STAR Protocols. 2(2):100595. PubMed
  73. Wang X, et al. 2021. Front Cell Dev Biol. 632805:9. PubMed
  74. Swidergall M, et al. 2019. Cell Rep. 28:423. PubMed
  75. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  76. Fujino T, et al. 2021. Nat Commun. 12:1826. PubMed
  77. Shi S, et al. 2020. Clin Cancer Res. 26:5990. PubMed
  78. Almutairi F, et al. 2021. Front Immunol. 12:772288. PubMed
  79. Magod P, et al. 2021. Cell Reports. 36(5):109480. PubMed
  80. Yoshimi A, et al. 2019. Nature. 574:273. PubMed
  81. Thomas S, et al. 2019. J Immunother Cancer. 7:214. PubMed
  82. Uchimura T et al. 2018. Immunity. 49(6):1049-1061 . PubMed
  83. Zhang X, et al. 2022. Pharmaceutics. 14:. PubMed
  84. Tang D, et al. 2020. Br J Haematol. 191:906. PubMed
  85. van Elsas MJ, et al. 2022. Int J Mol Sci. 23:. PubMed
  86. Francian A, et al. 2021. J Drug Target. 29:754. PubMed
  87. Antunes KH, et al. 2022. Front Immunol. 13:867022. PubMed
  88. Mastandrea I, et al. 2022. STAR Protoc. 3:101106. PubMed
  89. Wu G, et al. 2020. Br J Pharmacol. 177:5063. PubMed
  90. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  91. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  92. Zhang F, et al. 2019. Immunity. 50:738. PubMed
  93. Liu H, et al. 2020. Cancer Cell. 37(3):324-339. PubMed
  94. Li X, et al. 2020. Mol Ther. 28:2430. PubMed
  95. Guo W, et al. 2022. J Immunother Cancer. 10:. PubMed
  96. Ren HZ, et al. 2022. J Clin Transl Hepatol. 10:1138. PubMed
  97. Utley A, et al. 2020. Cell Rep. 31:107815. PubMed
  98. Utz B, et al. 2020. Sci Rep. 10:18733. PubMed
  99. Hiramoto T, et al. 2018. Mol Ther. 26:1255. PubMed
  100. Yu VWC, et al. 2017. Cell. 168:944. PubMed
  101. Wang GZ, et al. 2019. Nat Commun. 10:1125. PubMed
  102. Chen X et al. 2017. Cell stem cell. 21(6):747-760 . PubMed
  103. Wang W, et al. 2022. Aging Cell. 21:e13630. PubMed
  104. Xie Z, et al. 2020. Light Sci Appl. 0.486805556. PubMed
  105. Court AC, et al. 2020. EMBO Rep. 21:e48052. PubMed
  106. Venturutti L, et al. 2020. Cell. 182(2):297-316.e27. PubMed
  107. Zhang W, et al. 2019. Oncol Lett. 17:815. PubMed
  108. Schadt L, et al. 2020. Cell Reports. 29(5):1236-1248.e7.. PubMed
  109. Hu Q, et al. 2018. Nat Biomed Eng. 0.660416667. PubMed
  110. Suryawanshi RK, et al. 2021. Nat Commun. 12:6020. PubMed
  111. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  112. Chauveau A, et al. 2020. Immunity. 52:794. PubMed
  113. Haikala HM, et al. 2019. Nat Commun. 10:620. PubMed
  114. Zhao X, et al. 2022. Nat Protoc. 17:2240. PubMed
  115. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  116. Reinfeld BI, et al. 2021. Nature. 593:282. PubMed
  117. Kruta M, et al. 2021. Cell Stem Cell. :. PubMed
  118. Liu Y, et al. 2017. Oncogene. 10.1038/onc.2017.209. PubMed
  119. Hu J, et al. 2019. Mol Ther Nucleic Acids. 16:650. PubMed
  120. Burr ML, et al. 2019. Cancer Cell. 36:385. PubMed
  121. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  122. Huang Z, et al. 2021. Nat Commun. 12:145. PubMed
  123. Zhu Y, et al. 2021. EMBO J. 40:e105320. PubMed
  124. Wang Y, et al. 2021. Front Microbiol. 12:701566. PubMed
  125. Zheng D, et al. 2022. Acta Pharm Sin B. 12:2740. PubMed
  126. Tomala J, et al. 2020. Methods Mol Biol. 2111:101. PubMed
  127. Wen M, et al. 2022. JCI Insight. Online ahead of print. PubMed
  128. Stirling ER, et al. 2022. J Immunother Cancer. 10:. PubMed
  129. Li H, et al. 2021. Adv Sci (Weinh). 2001596:8. PubMed
  130. Tomay F, et al. 2019. J Transl Med. 17:237. PubMed
  131. Xiong W, et al. 2022. Adv Sci (Weinh). 9:e2103029. PubMed
  132. Xiao L, et al. 2021. Clin Cancer Res. 27:4338. PubMed
  133. Huang L, et al. 2021. Breast Cancer Res Treat. Online ahead of print. PubMed
  134. Han F, et al. 2020. Invest Ophthalmol Vis Sci. 61:24. PubMed
  135. Wang X, et al. 2020. Nat Commun. 4.505555556. PubMed
  136. Johnson DC, et al. 2020. Cell Death Dis. 0.894444444. PubMed
  137. Evgin L, et al. 2020. Nat Commun. 2.671527778. PubMed
  138. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  139. Xu P, et al. 2020. Cancer Immunol Res. 8:1193. PubMed
  140. Xi‐Zhi J Guo et al. 2018. Immunity. 49(3):531-544 . PubMed
  141. Subramanian K, et al. 2019. Nat Microbiol. 4:62. PubMed
  142. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  143. Chen C, et al. 2021. J Virol. 95:e0082921. PubMed
  144. Martinez-Turtos A, et al. 2022. Oncoimmunology. 11:2116844. PubMed
  145. Zeng Q, et al. 2022. iScience. 25:105151. PubMed
  146. Adnan-Awad S, et al. 2020. Leukemia. . PubMed
  147. Liu Y, et al. 2020. Oncol Lett. 2369:20. PubMed
  148. Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
  149. Cianciaruso C, et al. 2020. Cell Reports. 27(10):3062-3080.e11.. PubMed
  150. Zhang J, et al. 2018. Nature. 553:91. PubMed
  151. Pascual-Pasto G, et al. 2022. J Immunother Cancer. 10:. PubMed
  152. Li Z, et al. 2022. Nat Commun. 13:6321. PubMed
  153. Olivo Pimentel V, et al. 2021. J Immunother Cancer. 9:. PubMed
  154. Li M, et al. 2021. Cancers (Basel). 13:. PubMed
  155. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
  156. Yu M, et al. 2021. Molecular Cell. 81(6):1216-1230.e9. PubMed
  157. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  158. Nechama M, et al. 2018. Nat Commun. 9:1603. PubMed
  159. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  160. Siddique SM, et al. 2019. Sci Rep. 9:13977. PubMed
  161. Kim S, et al. 2020. Autophagy. :1. PubMed
  162. Lazarian G, et al. 2021. Cancer Cell. 39(3):380-393.e8. PubMed
  163. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  164. Olson CA, et al. 2021. Cell Host Microbe. 29:1378. PubMed
  165. Li K, et al. 2020. Nat Commun. 4.844444444. PubMed
  166. Hering L, et al. 2020. Front Immunol. 1.747222222. PubMed
  167. Yoshida S, et al. 2022. PLoS One. 17:e0264317. PubMed
  168. Zhong C, et al. 2021. J Virol. 95:e0092521. PubMed
  169. Kelley WJ, et al. 2022. JCI Insight. 7: . PubMed
  170. Wang Y, et al. 2021. Cell Reports. 36(6):109516. PubMed
  171. Hidalgo San Jose L, et al. 2020. Cell Rep. 30:69. PubMed
  172. Hao L, et al. 2021. Br J Pharmacol. 178:4726. PubMed
  173. Lau P, et al. 2022. Cell Mol Immunol. :. PubMed
  174. Arora S, et al. 2021. Med (N Y). 2:938. PubMed
  175. Li H, et al. 2022. iScience. 25:104481. PubMed
  176. Gardenier J, et al. 2017. Nat Commun. 8:14345. PubMed
  177. Heyde A, et al. 2021. Cell. 184(5):1348-1361.e22. PubMed
  178. Zeng A, et al. 2020. Oncol Rep. . PubMed
  179. Das A, et al. 2020. J Bone Miner Res. 36:199. PubMed
  180. Agelidis A, et al. 2017. Cell Rep. 10.1016/j.celrep.2017.06.041. PubMed
  181. Sartorius R, et al. 2018. Front Immunol. 1.413888889. PubMed
  182. Hong Y, et al. 2019. J Extracell Vesicles. 8:1670893. PubMed
  183. Lightman SM, et al. 2020. Cell Reports. 1.086805556. PubMed
  184. Kujur W, et al. 2020. PLoS Pathog. 16:e1009132. PubMed
  185. Wang X, et al. 2021. Sci Transl Med. 13:. PubMed
  186. Rappe JCF, et al. 2021. J Exp Med. 218:. PubMed
  187. Lee A, et al. 2022. Nat Commun. 13:549. PubMed
  188. Tripathi D, et al. 2016. Nat Commun. 7:13896. PubMed
  189. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  190. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  191. Akhtar MN, et al. 2020. PLoS Pathog. 16:e1009136. PubMed
  192. Zhang J, et al. 2021. Stem Cell Res Ther. 12:579. PubMed
  193. Chang MH, et al. 2021. Cell Rep. 37:109902. PubMed
  194. Xie Z, et al. 2020. Light Sci Appl. 9:161. PubMed
  195. Lake CM, et al. 2021. Cell Death Dis. 12:400. PubMed
  196. Koyama M, et al. 2015. J Exp Med. 212: 1303 - 1321. PubMed
  197. Morse M, et al. 2016. Lupus. 25: 81 - 87. PubMed
  198. Calabrese DR, et al. 2020. J Clin Invest. . PubMed
  199. Bergmann CA, et al. 2022. Cells. 11:. PubMed
  200. Akhtar MN, et al. 2022. MBio. 13:e0330921. PubMed
  201. Balakrishnan PB, et al. 2022. Nano Res. 15:2300. PubMed
  202. Shi X, et al. 2022. Proc Natl Acad Sci U S A. 119:e2208506119. PubMed
  203. Ho HM, et al. 2022. Pharmaceutics. 14:. PubMed
  204. Sparbier CE, et al. 2023. Nat Cell Biol. 25:258. PubMed
  205. Pan Y, et al. 2023. Adv Sci (Weinh). 10:e2206792. PubMed
  206. Wang X, et al. 2023. J Immunother Cancer. 11:. PubMed
  207. Liu N, et al. 2023. Cell Death Dis. 14:170. PubMed
  208. Gupta T, et al. 2023. Front Immunol. 14:1044703. PubMed
  209. Mabire M, et al. 2023. Nat Commun. 14:1830. PubMed
  210. Fu S, et al. 2023. Nat Commun. 14:2248. PubMed
  211. Li T, et al. 2023. Nat Commun. 14:2498. PubMed
  212. Zhang Z, et al. 2023. Aging Dis. 14:966. PubMed
  213. Bhaskar A, et al. 2023. iScience. 26:106644. PubMed
  214. Changsheng H, et al. 2023. Sci Adv. 9:eade4186. PubMed
  215. Cansever D, et al. 2023. Nat Immunol. . PubMed
  216. Hou X, et al. 2020. Cell Reports. 28(1):172-189.e7.. PubMed
  217. Liu J, et al. 2019. Immunity. 50:600. PubMed
  218. Rivas MA, et al. 2021. Nat Immunol. 22:240. PubMed
  219. Xiang G, et al. 2022. Cell Death Dis. 13:451. PubMed
  220. Pani F, et al. 2021. Endocrinology. 162:. PubMed
  221. Hilfenhaus G, et al. 2021. Cancer Res. 81:619. PubMed
  222. Denny L, et al. 2021. Clin Transl Immunology. 10:e1234. PubMed
  223. Ramos SA, et al. 2022. J Allergy Clin Immunol. 149:767. PubMed
  224. Zhou Y, et al. 2021. Methods Mol Biol. 2388:35. PubMed
  225. Sugiura A, et al. 2022. Immunity. 55:65. PubMed
  226. Alam A, et al. 2022. Cancer Cell. 40:153. PubMed
  227. Cautivo KM, et al. 2022. Immunity. 55:254. PubMed
  228. Qi X, et al. 2022. FASEB J. 36:e22250. PubMed
  229. van Dierendonck XAMH, et al. 2022. Proc Natl Acad Sci U S A. 119:e2114739119. PubMed
  230. Corral D, et al. 2022. Cell Rep. 39:110715. PubMed
  231. Tu J, et al. 2022. Cancer Sci. 113:2496. PubMed
  232. Dolfi B, et al. 2022. Cell Rep. 39:110949. PubMed
  233. Du M, et al. 2022. Cancer Sci. 113:2974. PubMed
  234. Tessaro FHG, et al. 2022. Cell Rep. 39:110977. PubMed
  235. Grégoire C, et al. 2022. Immunity. 55:1216. PubMed
  236. Zhu J, et al. 2022. Research (Wash D C). 2022:9816272. PubMed
  237. Zhang Z, et al. 2022. Integr Cancer Ther. 21:15347354221138534. PubMed
  238. Miró L, et al. 2022. Cancers (Basel). 14: . PubMed
  239. An HW, et al. 2022. Cell Rep. 41:111878. PubMed
  240. Jin SM, et al. 2023. Nat Nanotechnol. :. PubMed
  241. Lin J, et al. 2023. Nat Commun. 14:224. PubMed
  242. Kang J, et al. 2023. JCI Insight. 8: . PubMed
  243. Chen Y, et al. 2023. Stem Cells Int. 2023:7482546. PubMed
  244. Li X, et al. 2022. Cell. 185:1709. PubMed
  245. Naito Y, et al. 2019. American Journal of Physiology-Renal Physiology. 318(1):F238-F247. PubMed
  246. Yang H, et al. 2019. Mol Metab. 23:24. PubMed
  247. Gabriely G, et al. 2021. iScience. 24:103347. PubMed
  248. Delvecchio FR, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:1543. PubMed
  249. Kim D, et al. 2021. Nanomicro Lett. 13:31. PubMed
  250. Sano T, et al. 2021. Cell Reports. 36:109608. PubMed
  251. Wilson RP, et al. 2019. PLoS Pathog. 15:e1007745. PubMed
  252. Yu VWC et al. 2016. Cell. 167(5):1310-1322 . PubMed
  253. Huang X, et al. 2019. Cancer Immunol Res. 1.388888889. PubMed
  254. Gupta SS, et al. 2019. Cell Rep. 29:1862. PubMed
  255. Fu X, et al. 2020. J Immunol. 205:2066. PubMed
  256. Song J, et al. 2021. J Am Heart Assoc. 10:e017329. PubMed
  257. Baram T, et al. 2021. Cells. 10:. PubMed
  258. Luo R, et al. 2021. Theranostics. 11:117. PubMed
  259. Pessoa Rodrigues C, et al. 2021. Sci Adv. 7:. PubMed
  260. Zhang S, et al. 2022. Cell Death Dis. 13:844. PubMed
  261. Forte E, et al. 2020. J Cell Mol Med. . PubMed
  262. Haque M, et al. 2021. STAR Protoc. 2:100264. PubMed
  263. Gruber T, et al. 2020. JCI Insight. 5:00. PubMed
  264. Yamamoto R et al. 2018. Cell stem cell. 22(4):600-607 . PubMed
  265. Greenberg J, et al. 2022. JCI Insight. Online ahead of print. PubMed
  266. Kremenovic M, et al. 2022. J Immunother Cancer. 10:. PubMed
  267. Peng Z, et al. 2021. STAR Protocols. 2(2):100595. PubMed
  268. Wang X, et al. 2021. Front Cell Dev Biol. 632805:9. PubMed
  269. Swidergall M, et al. 2019. Cell Rep. 28:423. PubMed
  270. Tsuchiya N, et al. 2020. Cell Reports. 29(1):162-175.e9.. PubMed
  271. Fujino T, et al. 2021. Nat Commun. 12:1826. PubMed
  272. Shi S, et al. 2020. Clin Cancer Res. 26:5990. PubMed
  273. Almutairi F, et al. 2021. Front Immunol. 12:772288. PubMed
  274. Magod P, et al. 2021. Cell Reports. 36(5):109480. PubMed
  275. Yoshimi A, et al. 2019. Nature. 574:273. PubMed
  276. Thomas S, et al. 2019. J Immunother Cancer. 7:214. PubMed
  277. Uchimura T et al. 2018. Immunity. 49(6):1049-1061 . PubMed
  278. Zhang X, et al. 2022. Pharmaceutics. 14:. PubMed
  279. Tang D, et al. 2020. Br J Haematol. 191:906. PubMed
  280. van Elsas MJ, et al. 2022. Int J Mol Sci. 23:. PubMed
  281. Francian A, et al. 2021. J Drug Target. 29:754. PubMed
  282. Antunes KH, et al. 2022. Front Immunol. 13:867022. PubMed
  283. Mastandrea I, et al. 2022. STAR Protoc. 3:101106. PubMed
  284. Wu G, et al. 2020. Br J Pharmacol. 177:5063. PubMed
  285. Zhang Z, et al. 2021. Oncoimmunology. 10:1912472. PubMed
  286. Parada-Kusz M, et al. 2018. Dis Model Mech. 11:. PubMed
  287. Zhang F, et al. 2019. Immunity. 50:738. PubMed
  288. Liu H, et al. 2020. Cancer Cell. 37(3):324-339. PubMed
  289. Li X, et al. 2020. Mol Ther. 28:2430. PubMed
  290. Guo W, et al. 2022. J Immunother Cancer. 10:. PubMed
  291. Ren HZ, et al. 2022. J Clin Transl Hepatol. 10:1138. PubMed
  292. Utley A, et al. 2020. Cell Rep. 31:107815. PubMed
  293. Utz B, et al. 2020. Sci Rep. 10:18733. PubMed
  294. Hiramoto T, et al. 2018. Mol Ther. 26:1255. PubMed
  295. Yu VWC, et al. 2017. Cell. 168:944. PubMed
  296. Wang GZ, et al. 2019. Nat Commun. 10:1125. PubMed
  297. Chen X et al. 2017. Cell stem cell. 21(6):747-760 . PubMed
  298. Wang W, et al. 2022. Aging Cell. 21:e13630. PubMed
  299. Xie Z, et al. 2020. Light Sci Appl. 0.486805556. PubMed
  300. Court AC, et al. 2020. EMBO Rep. 21:e48052. PubMed
  301. Venturutti L, et al. 2020. Cell. 182(2):297-316.e27. PubMed
  302. Zhang W, et al. 2019. Oncol Lett. 17:815. PubMed
  303. Schadt L, et al. 2020. Cell Reports. 29(5):1236-1248.e7.. PubMed
  304. Hu Q, et al. 2018. Nat Biomed Eng. 0.660416667. PubMed
  305. Suryawanshi RK, et al. 2021. Nat Commun. 12:6020. PubMed
  306. Du Y, et al. 2022. Nat Commun. 13:231. PubMed
  307. Chauveau A, et al. 2020. Immunity. 52:794. PubMed
  308. Haikala HM, et al. 2019. Nat Commun. 10:620. PubMed
  309. Zhao X, et al. 2022. Nat Protoc. 17:2240. PubMed
  310. Zuo W, et al. 2022. Cell Death Discov. 8:257. PubMed
  311. Reinfeld BI, et al. 2021. Nature. 593:282. PubMed
  312. Kruta M, et al. 2021. Cell Stem Cell. :. PubMed
  313. Liu Y, et al. 2017. Oncogene. 10.1038/onc.2017.209. PubMed
  314. Hu J, et al. 2019. Mol Ther Nucleic Acids. 16:650. PubMed
  315. Burr ML, et al. 2019. Cancer Cell. 36:385. PubMed
  316. Liang J, et al. 2020. Sci Adv. 6:eabc3646. PubMed
  317. Huang Z, et al. 2021. Nat Commun. 12:145. PubMed
  318. Zhu Y, et al. 2021. EMBO J. 40:e105320. PubMed
  319. Wang Y, et al. 2021. Front Microbiol. 12:701566. PubMed
  320. Zheng D, et al. 2022. Acta Pharm Sin B. 12:2740. PubMed
  321. Tomala J, et al. 2020. Methods Mol Biol. 2111:101. PubMed
  322. Wen M, et al. 2022. JCI Insight. Online ahead of print. PubMed
  323. Stirling ER, et al. 2022. J Immunother Cancer. 10:. PubMed
  324. Li H, et al. 2021. Adv Sci (Weinh). 2001596:8. PubMed
  325. Tomay F, et al. 2019. J Transl Med. 17:237. PubMed
  326. Xiong W, et al. 2022. Adv Sci (Weinh). 9:e2103029. PubMed
  327. Xiao L, et al. 2021. Clin Cancer Res. 27:4338. PubMed
  328. Huang L, et al. 2021. Breast Cancer Res Treat. Online ahead of print. PubMed
  329. Han F, et al. 2020. Invest Ophthalmol Vis Sci. 61:24. PubMed
  330. Wang X, et al. 2020. Nat Commun. 4.505555556. PubMed
  331. Johnson DC, et al. 2020. Cell Death Dis. 0.894444444. PubMed
  332. Evgin L, et al. 2020. Nat Commun. 2.671527778. PubMed
  333. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  334. Xu P, et al. 2020. Cancer Immunol Res. 8:1193. PubMed
  335. Xi‐Zhi J Guo et al. 2018. Immunity. 49(3):531-544 . PubMed
  336. Subramanian K, et al. 2019. Nat Microbiol. 4:62. PubMed
  337. Yu H, et al. 2021. Front Oncol. 11:736882. PubMed
  338. Chen C, et al. 2021. J Virol. 95:e0082921. PubMed
  339. Martinez-Turtos A, et al. 2022. Oncoimmunology. 11:2116844. PubMed
  340. Zeng Q, et al. 2022. iScience. 25:105151. PubMed
  341. Adnan-Awad S, et al. 2020. Leukemia. . PubMed
  342. Liu Y, et al. 2020. Oncol Lett. 2369:20. PubMed
  343. Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
  344. Cianciaruso C, et al. 2020. Cell Reports. 27(10):3062-3080.e11.. PubMed
  345. Zhang J, et al. 2018. Nature. 553:91. PubMed
  346. Pascual-Pasto G, et al. 2022. J Immunother Cancer. 10:. PubMed
  347. Li Z, et al. 2022. Nat Commun. 13:6321. PubMed
  348. Olivo Pimentel V, et al. 2021. J Immunother Cancer. 9:. PubMed
  349. Li M, et al. 2021. Cancers (Basel). 13:. PubMed
  350. Jiang L, et al. 2020. Cell. 183(5):1219-1233.e18. PubMed
  351. Yu M, et al. 2021. Molecular Cell. 81(6):1216-1230.e9. PubMed
  352. Liu P, et al. 2020. Mol Cell. 748:77. PubMed
  353. Nechama M, et al. 2018. Nat Commun. 9:1603. PubMed
  354. Liu YG, et al. 2019. FASEB J. 33:5018. PubMed
  355. Siddique SM, et al. 2019. Sci Rep. 9:13977. PubMed
  356. Kim S, et al. 2020. Autophagy. :1. PubMed
  357. Lazarian G, et al. 2021. Cancer Cell. 39(3):380-393.e8. PubMed
  358. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  359. Olson CA, et al. 2021. Cell Host Microbe. 29:1378. PubMed
  360. Li K, et al. 2020. Nat Commun. 4.844444444. PubMed
  361. Hering L, et al. 2020. Front Immunol. 1.747222222. PubMed
  362. Yoshida S, et al. 2022. PLoS One. 17:e0264317. PubMed
  363. Zhong C, et al. 2021. J Virol. 95:e0092521. PubMed
  364. Kelley WJ, et al. 2022. JCI Insight. 7: . PubMed
  365. Wang Y, et al. 2021. Cell Reports. 36(6):109516. PubMed
  366. Hidalgo San Jose L, et al. 2020. Cell Rep. 30:69. PubMed
  367. Hao L, et al. 2021. Br J Pharmacol. 178:4726. PubMed
  368. Lau P, et al. 2022. Cell Mol Immunol. :. PubMed
  369. Arora S, et al. 2021. Med (N Y). 2:938. PubMed
  370. Li H, et al. 2022. iScience. 25:104481. PubMed
  371. Gardenier J, et al. 2017. Nat Commun. 8:14345. PubMed
  372. Heyde A, et al. 2021. Cell. 184(5):1348-1361.e22. PubMed
  373. Zeng A, et al. 2020. Oncol Rep. . PubMed
  374. Das A, et al. 2020. J Bone Miner Res. 36:199. PubMed
  375. Agelidis A, et al. 2017. Cell Rep. 10.1016/j.celrep.2017.06.041. PubMed
  376. Sartorius R, et al. 2018. Front Immunol. 1.413888889. PubMed
  377. Hong Y, et al. 2019. J Extracell Vesicles. 8:1670893. PubMed
  378. Lightman SM, et al. 2020. Cell Reports. 1.086805556. PubMed
  379. Kujur W, et al. 2020. PLoS Pathog. 16:e1009132. PubMed
  380. Wang X, et al. 2021. Sci Transl Med. 13:. PubMed
  381. Rappe JCF, et al. 2021. J Exp Med. 218:. PubMed
  382. Lee A, et al. 2022. Nat Commun. 13:549. PubMed
  383. Tripathi D, et al. 2016. Nat Commun. 7:13896. PubMed
  384. Pessoa Rodrigues C, et al. 2020. Sci Adv. 6:eaaz4815. PubMed
  385. Song X, et al. 2022. Transl Oncol. 15:101306. PubMed
  386. Akhtar MN, et al. 2020. PLoS Pathog. 16:e1009136. PubMed
  387. Zhang J, et al. 2021. Stem Cell Res Ther. 12:579. PubMed
  388. Chang MH, et al. 2021. Cell Rep. 37:109902. PubMed
  389. Xie Z, et al. 2020. Light Sci Appl. 9:161. PubMed
  390. Lake CM, et al. 2021. Cell Death Dis. 12:400. PubMed
RRID
AB_2561455 (BioLegend Cat. No. 100235)
AB_2561456 (BioLegend Cat. No. 100236)

Antigen Details

Structure
Ig superfamily, CD3/TCR, 20 kD
Distribution

Thymocytes (differentiation dependent), mature T cells, NK-T cells

Function
Antigen recognition, TCR signal transduction, T cell activation
Ligand/Receptor
Peptide antigen/MHC-complex
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Davis MM. 1990. Annu. Rev. Biochem. 59:475.
3. Weiss A, et al. 1994. Cell 76:263.

Gene ID
12502 View all products for this Gene ID
UniProt
View information about CD3 on UniProt.org

Other Formats

View All CD3 Reagents Request Custom Conjugation
Description Clone Applications
Brilliant Violet 711™ anti-mouse CD3 17A2 FC
Biotin anti-mouse CD3 17A2 FC,IHC-F
PE/Dazzle™ 594 anti-mouse CD3 17A2 FC
APC/Fire™ 750 anti-mouse CD3 17A2 FC
Brilliant Violet 750™ anti-mouse CD3 17A2 FC
TotalSeq™-A0182 anti-mouse CD3 17A2 PG
TotalSeq™-B0182 anti-mouse CD3 17A2 PG
Spark Blue™ 550 anti-mouse CD3 17A2 FC
Spark NIR™ 685 anti-mouse CD3 17A2 FC
TotalSeq™-C0182 anti-mouse CD3 17A2 PG
APC/Fire™ 810 anti-mouse CD3 17A2 FC
PE/Fire™ 640 anti-mouse CD3 17A2 FC
Spark YG™ 570 anti-mouse CD3 17A2 IHC-F
PE/Fire™ 700 anti-mouse CD3 17A2 FC
Test 17A2 5 17A2
FITC anti-mouse CD3 17A2 FC
PE anti-mouse CD3 17A2 FC
Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Alexa Fluor® 647 anti-mouse CD3 17A2 FC,IHC-F,3D IHC,SB
Alexa Fluor® 488 anti-mouse CD3 17A2 FC,IHC-F,3D IHC
Pacific Blue™ anti-mouse CD3 17A2 FC
Alexa Fluor® 700 anti-mouse CD3 17A2 FC
PerCP/Cyanine5.5 anti-mouse CD3 17A2 FC
PE/Cyanine7 anti-mouse CD3 17A2 FC
APC/Cyanine7 anti-mouse CD3 17A2 FC
Brilliant Violet 421™ anti-mouse CD3 17A2 FC,ICC
Brilliant Violet 570™ anti-mouse CD3 17A2 FC
Brilliant Violet 650™ anti-mouse CD3 17A2 FC
Brilliant Violet 785™ anti-mouse CD3 17A2 FC
Brilliant Violet 510™ anti-mouse CD3 17A2 FC
APC anti-mouse CD3 17A2 FC
Ultra-LEAF™ Purified anti-mouse CD3 17A2 FC,IHC-F,IP,ICC
Brilliant Violet 605™ anti-mouse CD3 17A2 FC
Alexa Fluor® 594 anti-mouse CD3 17A2 IHC-F,FC,3D IHC,SB
PE/Cyanine5 anti-mouse CD3 17A2 FC
Spark Blue™ 574 anti-mouse CD3 Antibody 17A2 FC
Spark Violet™ 423 anti-mouse CD3 17A2 FC
PE/Fire™ 810 anti-mouse CD3 17A2 FC
Spark Red™ 718 anti-mouse CD3 17A2 FC
Spark UV™ 387 anti-mouse CD3 17A2 FC
PerCP/Fire™ 780 anti-mouse CD3 Antibody 17A2 FC
PerCP anti-mouse CD3 Antibody 17A2 FC
Spark YG™ 581 anti-mouse CD3 (Flexi-Fluor™) 17A2 FC
Spark YG™ 593 anti-mouse CD3 (Flexi-Fluor™) Antibody 17A2 FC
Spark PLUS B488™ anti-mouse CD3 17A2 FC
Go To Top Version: 1    Revision Date: 11-30-2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account